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Items: 1 to 20 of 37

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
The Preventive Effects of Salubrinal against Pyrethroid-Induced Disruption of Adult Hippocampal Neurogenesis in Mice
Abigail C. Toltin, Abdelmadjid Belkadi, Laura M. Gamba, Muhammad M. Hossain
Int J Mol Sci. 2023 Nov; 24(21): 15614. Published online 2023 Oct 26. doi: 10.3390/ijms242115614
PMCID:
PMC10648946
AbstractArticlePDF–7.5M
3.
The Role of Caspase-12 in Retinal Bystander Cell Death and Innate Immune Responses against MCMV Retinitis
Xinyan Zhang, Jinxian Xu, Brendan Marshall, Zheng Dong, Sylvia B. Smith, Ming Zhang
Int J Mol Sci. 2021 Aug; 22(15): 8135. Published online 2021 Jul 29. doi: 10.3390/ijms22158135
PMCID:
PMC8348425
AbstractArticlePDF–6.8M
4.
Caspase-12 Is Present During Craniofacial Development and Participates in Regulation of Osteogenic Markers
Barbora Vesela, Adela Kratochvilova, Eva Svandova, Petr Benes, Kamila Rihova, Anne Poliard, Eva Matalova
Front Cell Dev Biol. 2020; 8: 589136. Published online 2020 Oct 15. doi: 10.3389/fcell.2020.589136
PMCID:
PMC7593616
AbstractArticlePDF–5.4M
5.
Inhibiting Caspase-12 Mediated Inflammasome Activation protects against Oxygen-Glucose Deprivation Injury in Primary Astrocytes
Lu Liu, Manli Chen, Kun Lin, Xuwu Xiang, Yueying Zheng, Shengmei Zhu
Int J Med Sci. 2020; 17(13): 1936–1945. Published online 2020 Jul 19. doi: 10.7150/ijms.44330
PMCID:
PMC7415396
AbstractArticlePDF–1.8M
6.
Characterisation of mice lacking the inflammatory caspases-1/11/12 reveals no contribution of caspase-12 to cell death and sepsis
Ranja Salvamoser, Kerstin Brinkmann, Lorraine A. O’Reilly, Lachlan Whitehead, Andreas Strasser, Marco J. Herold
Cell Death Differ. 2019 Jun; 26(6): 1124–1137. Published online 2018 Aug 28. doi: 10.1038/s41418-018-0188-2
PMCID:
PMC6748106
AbstractArticlePDF–3.0M
7.
Mouse screen reveals multiple new genes underlying mouse and human hearing loss
Neil J. Ingham, Selina A. Pearson, Valerie E. Vancollie, Victoria Rook, Morag A. Lewis, Jing Chen, Annalisa Buniello, Elisa Martelletti, Lorenzo Preite, Chi Chung Lam, Felix D. Weiss, Zӧe Powis, Pim Suwannarat, Christopher J. Lelliott, Sally J. Dawson, Jacqueline K. White, Karen P. Steel
PLoS Biol. 2019 Apr; 17(4): e3000194. Published online 2019 Apr 11. doi: 10.1371/journal.pbio.3000194
PMCID:
PMC6459510
AbstractArticlePDF–5.1M
8.
Caspase-12, but not caspase-11, inhibits obesity and insulin resistance
Alexander M. Skeldon, Alexandre Morizot, Todd Douglas, Nicola Santoro, Romy Kursawe, Julia Kozlitina, Sonia Caprio, Wajahat Z. Mehal, Maya Saleh
J Immunol. Author manuscript; available in PMC 2017 Sep 12.
Published in final edited form as: J Immunol. 2016 Jan 1; 196(1): 437–447. Published online 2015 Nov 18. doi: 10.4049/jimmunol.1501529
PMCID:
PMC5594569
AbstractArticlePDF–3.3M
9.
IKKα controls ATG16L1 degradation to prevent ER stress during inflammation
Michaela A. Diamanti, Jalaj Gupta, Moritz Bennecke, Tiago De Oliveira, Mallika Ramakrishnan, Anne K. Braczynski, Benjamin Richter, Petra Beli, Yinling Hu, Maya Saleh, Michel Mittelbronn, Ivan Dikic, Florian R. Greten
J Exp Med. 2017 Feb; 214(2): 423–437. doi: 10.1084/jem.20161867
PMCID:
PMC5294863
AbstractArticlePDF–2.7M
10.
Enhancing Autophagy with Drugs or Lung-directed Gene Therapy Reverses the Pathological Effects of Respiratory Epithelial Cell Proteinopathy
Tunda Hidvegi, Donna B. Stolz, John F. Alcorn, Samuel A. Yousem, Jieru Wang, Adriana S. Leme, A. McGarry Houghton, Pamela Hale, Michael Ewing, Houming Cai, Evelyn Akpadock Garchar, Nunzia Pastore, Patrizia Annunziata, Naftali Kaminski, Joseph Pilewski, Steven D. Shapiro, Stephen C. Pak, Gary A. Silverman, Nicola Brunetti-Pierri, David H. Perlmutter
J Biol Chem. 2015 Dec 11; 290(50): 29742–29757. Published online 2015 Oct 22. doi: 10.1074/jbc.M115.691253
PMCID:
PMC4705969
AbstractArticlePDF–3.5M
11.
Minimal role for caspase 12 in the unfolded protein response in oligodendrocytes in vivo
Ramaswamy Sharma, Alexander Gow
J Neurochem. Author manuscript; available in PMC 2015 Oct 15.
Published in final edited form as: J Neurochem. 2007 May; 101(4): 889–897. Published online 2007 Mar 30. doi: 10.1111/j.1471-4159.2007.04541.x
PMCID:
PMC4607047
AbstractArticlePDF–1.1M
12.
Targeting Caspase-12 to Preserve Vision in Mice With Inherited Retinal Degeneration
Yogesh Bhootada, Shreyasi Choudhury, Clark Gully, Marina Gorbatyuk
Invest Ophthalmol Vis Sci. 2015 Jul; 56(8): 4725–4733. Published online 2015 Jul 23. doi: 10.1167/iovs.15-16924
PMCID:
PMC4516015
AbstractArticlePDF–1.3M
13.
Preparation of anti-mouse caspase-12 mRNA hammerhead ribozyme and identification of its activity in vitro
Shan Jiang, Qing Xie, Wei Zhang, Xia-Qiu Zhou, You-Xin Jin
World J Gastroenterol. 2005 Jul 14; 11(26): 4094–4097. Published online 2005 Jul 14. doi: 10.3748/wjg.v11.i26.4094
PMCID:
PMC4502108
AbstractArticlePDF–575K
14.
Caspase-12 mediates carbon tetrachloride-induced hepatocyte apoptosis in mice
Hua Liu, Zhe Wang, Michael J Nowicki
World J Gastroenterol. 2014 Dec 28; 20(48): 18189–18198. Published online 2014 Dec 28. doi: 10.3748/wjg.v20.i48.18189
PMCID:
PMC4277956
AbstractArticlePDF–2.4M
15.
Caspase-12 ablation preserves muscle function in the mdx mouse
Catherine Moorwood, Elisabeth R. Barton
Hum Mol Genet. 2014 Oct 15; 23(20): 5325–5341. Published online 2014 May 30. doi: 10.1093/hmg/ddu249
PMCID:
PMC4168821
AbstractArticlePDF–1.7M
16.
Caspase-12 controls West Nile virus infection via the viral RNA receptor RIG-I
Penghua Wang, Alvaro Arjona, Yue Zhang, Hameeda Sultana, Jianfeng Dai, Long Yang, Philippe M LeBlanc, Karine Doiron, Maya Saleh, Erol Fikrig
Nat Immunol. Author manuscript; available in PMC 2013 Jul 16.
Published in final edited form as: Nat Immunol. 2010 Oct; 11(10): 912–919. Published online 2010 Sep 5. doi: 10.1038/ni.1933
PMCID:
PMC3712356
AbstractArticlePDF–3.9M
17.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
18.
Pharmacological Modulation of the Retinal Unfolded Protein Response in Bardet-Biedl Syndrome Reduces Apoptosis and Preserves Light Detection Ability
Anais Mockel, Cathy Obringer, Theodorus B. M. Hakvoort, Mathias Seeliger, Wouter H. Lamers, Corinne Stoetzel, Hélène Dollfus, Vincent Marion
J Biol Chem. 2012 Oct 26; 287(44): 37483–37494. Published online 2012 Aug 6. doi: 10.1074/jbc.M112.386821
PMCID:
PMC3481343
AbstractArticlePDF–4.0M
19.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
20.
No death without life: vital functions of apoptotic effectors
L Galluzzi, N Joza, E Tasdemir, MC Maiuri, M Hengartner, JM Abrams, N Tavernarakis, J Penninger, F Madeo, G Kroemer
Cell Death Differ. Author manuscript; available in PMC 2010 Aug 9.
Published in final edited form as: Cell Death Differ. 2008 Jul; 15(7): 1113–1123. Published online 2008 Feb 29. doi: 10.1038/cdd.2008.28
PMCID:
PMC2917777
AbstractArticlePDF–347K

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