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Items: 1 to 20 of 40

1.
Regulation of ClC-2 Chloride Channel Proteostasis by Molecular Chaperones: Correction of Leukodystrophy-Associated Defect
Ssu-Ju Fu, Meng-Chun Hu, Cheng-Tsung Hsiao, An-Ting Cheng, Tsung-Yu Chen, Chung-Jiuan Jeng, Chih-Yung Tang
Int J Mol Sci. 2021 Jun; 22(11): 5859. Published online 2021 May 30. doi: 10.3390/ijms22115859
PMCID:
PMC8197790
AbstractArticlePDF–5.7M
2.
Cellular basis of ClC-2 Cl− channel–related brain and testis pathologies
Corinna Göppner, Audrey H. Soria, Maja B. Hoegg-Beiler, Thomas J. Jentsch
J Biol Chem. 2021 Jan-Jun; 296: 100074. Published online 2020 Nov 23. doi: 10.1074/jbc.RA120.016031
PMCID:
PMC7949093
AbstractArticlePDF–5.4M
3.
Short Chain Fatty Acids Effect on Chloride Channel ClC-2 as a Possible Mechanism for Lubiprostone Intestinal Action
Marcelo A. Catalán, Francisca Julio-Kalajzić, María Isabel Niemeyer, Luis Pablo Cid, Francisco V. Sepúlveda
Cells. 2020 Aug; 9(8): 1781. Published online 2020 Jul 26. doi: 10.3390/cells9081781
PMCID:
PMC7464869
AbstractArticlePDF–1.4M
4.
CUL4-DDB1-CRBN E3 Ubiquitin Ligase Regulates Proteostasis of ClC-2 Chloride Channels: Implication for Aldosteronism and Leukodystrophy
Ssu-Ju Fu, Meng-Chun Hu, Yi-Jheng Peng, Hsin-Yu Fang, Cheng-Tsung Hsiao, Tsung-Yu Chen, Chung-Jiuan Jeng, Chih-Yung Tang
Cells. 2020 Jun; 9(6): 1332. Published online 2020 May 26. doi: 10.3390/cells9061332
PMCID:
PMC7348978
AbstractArticlePDF–5.6M
5.
Mouse Models of Inherited Retinal Degeneration with Photoreceptor Cell Loss
Gayle B. Collin, Navdeep Gogna, Bo Chang, Nattaya Damkham, Jai Pinkney, Lillian F. Hyde, Lisa Stone, Jürgen K. Naggert, Patsy M. Nishina, Mark P. Krebs
Cells. 2020 Apr; 9(4): 931. Published online 2020 Apr 10. doi: 10.3390/cells9040931
PMCID:
PMC7227028
AbstractArticlePDF–5.4M
6.
Elevated aldosterone and blood pressure in a mouse model of familial hyperaldosteronism with ClC-2 mutation
Julia Schewe, Eric Seidel, Sofia Forslund, Lajos Marko, Jörg Peters, Dominik N. Muller, Christoph Fahlke, Gabriel Stölting, Ute Scholl
Nat Commun. 2019; 10: 5155. Published online 2019 Nov 14. doi: 10.1038/s41467-019-13033-4
Correction in:
Nat Commun. 2022; 13: 3066.
PMCID:
PMC6856192
AbstractArticlePDF–2.2M
7.
Pathogenesis of hypertension in a mouse model for human CLCN2 related hyperaldosteronism
Corinna Göppner, Ian J. Orozco, Maja B. Hoegg-Beiler, Audrey H. Soria, Christian A. Hübner, Fabio L. Fernandes-Rosa, Sheerazed Boulkroun, Maria-Christina Zennaro, Thomas J. Jentsch
Nat Commun. 2019; 10: 4678. Published online 2019 Oct 15. doi: 10.1038/s41467-019-12113-9
PMCID:
PMC6794291
AbstractArticlePDF–1.8M
8.
Leukoencephalopathy upon Disruption of the Chloride Channel ClC-2
Judith Blanz, Michaela Schweizer, Muriel Auberson, Hannes Maier, Adrian Muenscher, Christian A. Hübner, Thomas J. Jentsch
J Neurosci. 2007 Jun 13; 27(24): 6581–6589. doi: 10.1523/JNEUROSCI.0338-07.2007
PMCID:
PMC6672451
AbstractArticlePDF–724K
9.
ClC-2 Voltage-Gated Channels Constitute Part of the Background Conductance and Assist Chloride Extrusion
Ilka Rinke, Judith Artmann, Valentin Stein
J Neurosci. 2010 Mar 31; 30(13): 4776–4786. doi: 10.1523/JNEUROSCI.6299-09.2010
PMCID:
PMC6632307
AbstractArticlePDF–1.2M
10.
Knockout of ClC-2 reveals critical functions of adherens junctions in colonic homeostasis and tumorigenicity
Younggeon Jin, Dina Ibrahim, Scott T. Magness, Anthony T. Blikslager
Am J Physiol Gastrointest Liver Physiol. 2018 Dec 1; 315(6): G966–G979. Published online 2018 Oct 4. doi: 10.1152/ajpgi.00087.2018
PMCID:
PMC6336945
AbstractArticle
11.
Mouse models of human ocular disease for translational research
Mark P. Krebs, Gayle B. Collin, Wanda L. Hicks, Minzhong Yu, Jeremy R. Charette, Lan Ying Shi, Jieping Wang, Jürgen K. Naggert, Neal S. Peachey, Patsy M. Nishina
PLoS One. 2017; 12(8): e0183837. Published online 2017 Aug 31. doi: 10.1371/journal.pone.0183837
PMCID:
PMC5578669
AbstractArticlePDF–26M
12.
Regulation of CLC-1 chloride channel biosynthesis by FKBP8 and Hsp90β
Yi-Jheng Peng, Jing-Jia Huang, Hao-Han Wu, Hsin-Ying Hsieh, Chia-Ying Wu, Shu-Ching Chen, Tsung-Yu Chen, Chih-Yung Tang
Sci Rep. 2016; 6: 32444. Published online 2016 Sep 1. doi: 10.1038/srep32444
PMCID:
PMC5007535
AbstractArticlePDF–3.0M
13.
Genetic Ablation of the ClC-2 Cl- Channel Disrupts Mouse Gastric Parietal Cell Acid Secretion
Meghali P. Nighot, Prashant K. Nighot, Thomas Y. Ma, Danuta H. Malinowska, Gary E. Shull, John Cuppoletti, Anthony T. Blikslager
PLoS One. 2015; 10(9): e0138174. Published online 2015 Sep 17. doi: 10.1371/journal.pone.0138174
PMCID:
PMC4574764
AbstractArticlePDF–15M
14.
Ion Channel Expression in the Developing Enteric Nervous System
Caroline S. Hirst, Jaime P. P. Foong, Lincon A. Stamp, Emily Fegan, Stephan Dent, Edward C. Cooper, Alan E. Lomax, Colin R. Anderson, Joel C. Bornstein, Heather M. Young, Sonja J. McKeown
PLoS One. 2015; 10(3): e0123436. Published online 2015 Mar 23. doi: 10.1371/journal.pone.0123436
PMCID:
PMC4370736
AbstractArticlePDF–9.5M
15.
A fluid secretion pathway unmasked by acinar-specific Tmem16A gene ablation in the adult mouse salivary gland
Marcelo A. Catalán, Yusuke Kondo, Gaspar Peña-Munzenmayer, Yasna Jaramillo, Frances Liu, Sooji Choi, Edward Crandall, Zea Borok, Per Flodby, Gary E. Shull, James E. Melvin
Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7): 2263–2268. Published online 2015 Feb 2. doi: 10.1073/pnas.1415739112
PMCID:
PMC4343136
AbstractArticlePDF–1.2M
16.
Chloride Channel ClC-2 is a Key Factor in the Development of DSS-Induced Murine Colitis
Prashant Nighot, Karen Young, Meghali Nighot, Manmeet Rawat, Eui J. Sung, Nitsan Maharshak, Scott E. Plevy, Thomas Ma, Anthony Blikslager
Inflamm Bowel Dis. Author manuscript; available in PMC 2014 Dec 1.
Published in final edited form as: Inflamm Bowel Dis. 2013 Dec; 19(13): 10.1097/MIB.0b013e3182a82ae9. doi: 10.1097/MIB.0b013e3182a82ae9
PMCID:
PMC3880115
AbstractArticlePDF–3.3M
17.
Dual activation of CFTR and CLCN2 by lubiprostone in murine nasal epithelia
Eric S. Schiffhauer, Neeraj Vij, Olga Kovbasnjuk, Po Wei Kang, Doug Walker, Seakwoo Lee, Pamela L. Zeitlin
Am J Physiol Lung Cell Mol Physiol. 2013 Mar 1; 304(5): L324–L331. Published online 2013 Jan 11. doi: 10.1152/ajplung.00277.2012
PMCID:
PMC3602739
AbstractArticle
18.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
19.
Sequential interaction of chloride and proton ions with the fast gate steer the voltage-dependent gating in ClC-2 chloride channels
Jorge E Sánchez-Rodríguez, José A De Santiago-Castillo, Juan Antonio Contreras-Vite, Pablo G Nieto-Delgado, Alejandra Castro-Chong, Jorge Arreola
J Physiol. 2012 Sep 1; 590(Pt 17): 4239–4253. Published online 2012 Jul 2. doi: 10.1113/jphysiol.2012.232660
PMCID:
PMC3473282
AbstractArticlePDF–1.5M
20.
GlialCAM, a Protein Defective in a Leukodystrophy, Serves as a ClC-2 Cl− Channel Auxiliary Subunit
Elena Jeworutzki, Tania López-Hernández, Xavier Capdevila-Nortes, Sònia Sirisi, Luiza Bengtsson, Marisol Montolio, Giovanni Zifarelli, Tanit Arnedo, Catrin S. Müller, Uwe Schulte, Virginia Nunes, Albert Martínez, Thomas J. Jentsch, Xavier Gasull, Michael Pusch, Raúl Estévez
Neuron. 2012 Mar 8; 73(5): 951–961. doi: 10.1016/j.neuron.2011.12.039
PMCID:
PMC3334819
AbstractArticle

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