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Select item 112311401.

CircCDC42-encoded CDC42-165aa regulates macrophage pyroptosis in Klebsiella pneumoniae infection through Pyrin inflammasome activation

Nana Xu, Jiebang Jiang, Fei Jiang, Guokai Dong, Li Meng, Meng Wang, Jing Chen, Cong Li, Yongping Shi, Sisi He, Rongpeng Li

Nat Commun. 2024; 15: 5730. Published online 2024 Jul 8. doi: 10.1038/s41467-024-50154-x

PMCID:: PMC11231140

Abstract Article PDF–3.0M

Select item 110478012.

Myeloid Deletion of Cdc42 Protects Liver From Hepatic Ischemia-Reperfusion Injury via Inhibiting Macrophage-Mediated Inflammation in Mice

Jing He, Meng-Yu Tang, Li-Xin Liu, Chen-Xian Kong, Wen Chen, Lu Wang, Shao-Bin Zhi, Hong-Wei Sun, Yu-Chun Huang, Guo-Yu Chen, Hong-Bo Xin, Ke-Yu Deng

Cell Mol Gastroenterol Hepatol. 2024; 17(6): 965–981. Published online 2024 Feb 9. doi: 10.1016/j.jcmgh.2024.01.023

PMCID:: PMC11047801

Abstract Article PDF–7.7M

Select item 110146573.

A BMP-controlled metabolic/epigenetic signaling cascade directs midfacial morphogenesis

Jingwen Yang, Lingxin Zhu, Haichun Pan, Hiroki Ueharu, Masako Toda, Qian Yang, Shawn A. Hallett, Lorin E. Olson, Yuji Mishina

J Clin Invest. 2024 Apr 15; 134(8): e165787. Published online 2024 Mar 11. doi: 10.1172/JCI165787

PMCID:: PMC11014657

Abstract Article PDF–16M

Select item 109176604.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 107693505.

Identification of new ciliary signaling pathways in the brain and insights into neurological disorders

Abdelhalim Loukil, Emma Ebright, Akiyoshi Uezu, Yudong Gao, Scott H Soderling, Sarah C. Goetz

Version 1. bioRxiv. Preprint. 2023 Dec 21. doi: 10.1101/2023.12.20.572700

PMCID:: PMC10769350

Abstract Article PDF–11M

Select item 107434766.

Loss of Cdc42 in Exocrine Acini Decreases Saliva Secretion but Increases Tear Secretion—A Potential Model of Exocrine Gland Senescence

Haruna Nagase, Akiko Shitara, Yuta Ohno, Keitaro Satoh, Masanori Kashimata

Int J Mol Sci. 2023 Dec; 24(24): 17220. Published online 2023 Dec 7. doi: 10.3390/ijms242417220

PMCID:: PMC10743476

Abstract Article PDF–12M

Select item 104878987.

TRIM67 Implicates in Regulating the Homeostasis and Synaptic Development of Mitral Cells in the Olfactory Bulb

Chunyu Cai, Qihui Luo, Lanlan Jia, Yu Xia, Xinting Lan, Xiaoli Wei, Shuai Shi, Yucong Liu, Yao Wang, Zongliang Xiong, Riyi Shi, Chao Huang, Zhengli Chen

Int J Mol Sci. 2023 Sep; 24(17): 13439. Published online 2023 Aug 30. doi: 10.3390/ijms241713439

PMCID:: PMC10487898

Abstract Article PDF–7.5M

Select item 100659608.

Biophysical forces mediated by respiration maintain lung alveolar epithelial cell fate

Kazushige Shiraishi, Parisha P. Shah, Michael P. Morley, Claudia Loebel, Garrett T. Santini, Jeremy Katzen, Maria C. Basil, Susan M. Lin, Joseph D. Planer, Edward Cantu, Dakota L. Jones, Ana N. Nottingham, Shanru Li, Fabian L. Cardenas-Diaz, Su Zhou, Jason A. Burdick, Rajan Jain, Edward E. Morrisey

Cell. Author manuscript; available in PMC 2024 Mar 30.

Published in final edited form as: Cell. 2023 Mar 30; 186(7): 1478–1492.e15. Published online 2023 Mar 3. doi: 10.1016/j.cell.2023.02.010

PMCID:: PMC10065960

Abstract Article PDF–3.1M

Select item 99382169.

Rescue of neuropsychiatric phenotypes in a mouse model of 16p11.2 duplication syndrome by genetic correction of an epilepsy network hub

Marc P. Forrest, Marc Dos Santos, Nicolas H. Piguel, Yi-Zhi Wang, Nicole A. Hawkins, Vikram A. Bagchi, Leonardo E. Dionisio, Sehyoun Yoon, Dina Simkin, Maria Dolores Martin-de-Saavedra, Ruoqi Gao, Katherine E. Horan, Alfred L. George, Jr., Mark S. LeDoux, Jennifer A. Kearney, Jeffrey N. Savas, Peter Penzes

Nat Commun. 2023; 14: 825. Published online 2023 Feb 17. doi: 10.1038/s41467-023-36087-x

PMCID:: PMC9938216

Abstract Article PDF–5.3M

Select item 948193310.

ALS-linked loss of Cyclin-F function affects HSP90

Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends

Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359

PMCID:: PMC9481933

Abstract Article PDF–3.5M

Select item 944002611.

CDC42 governs normal oviduct multiciliogenesis through activating AKT to ensure timely embryo transport

Ruiwei Jiang, Xiaofang Tang, Jiale Pan, Gaizhen Li, Ningjie Yang, Yedong Tang, Shilei Bi, Han Cai, Qionghua Chen, Dunjin Chen, Haibin Wang, Shuangbo Kong

Cell Death Dis. 2022 Sep; 13(9): 757. Published online 2022 Sep 2. doi: 10.1038/s41419-022-05184-y

PMCID:: PMC9440026

Abstract Article PDF–7.5M

Select item 939985412.

Cdc42 upregulation under high glucose induces podocyte apoptosis and impairs β-cell insulin secretion

Shan Jiang, Chun-mei Xu, Shuai Yao, Rui Zhang, Xian-zhi Li, Ru-zhen Zhang, Tian-yue Xie, Yi-qian Xing, Qian Zhang, Xiao-jun Zhou, Lin Liao, Jian-jun Dong

Front Endocrinol (Lausanne) 2022; 13: 905703. Published online 2022 Aug 10. doi: 10.3389/fendo.2022.905703

PMCID:: PMC9399854

Abstract Article PDF–4.2M

Select item 928970913.

TRIM27 cooperates with STK38L to inhibit ULK1‐mediated autophagy and promote tumorigenesis

Yi Yang, Yifu Zhu, Shuai Zhou, Peipei Tang, Ran Xu, Yuwei Zhang, Dongping Wei, Jian Wen, Rick F Thorne, Xu Dong Zhang, Jun‐Lin Guan, Lianxin Liu, Mian Wu, Song Chen

EMBO J. 2022 Jul; 41(14): e109777. Published online 2022 Jun 7. doi: 10.15252/embj.2021109777

PMCID:: PMC9289709

Abstract Article PDF–2.3M

Select item 923958014.

Bcar1/p130Cas is essential for ventricular development and neural crest cell remodelling of the cardiac outflow tract

Marwa Mahmoud, Ian Evans, Laura Wisniewski, Yuen Tam, Claire Walsh, Simon Walker-Samuel, Paul Frankel, Peter Scambler, Ian Zachary

Cardiovasc Res. 2022 May; 118(8): 1993–2005. Published online 2021 Jul 16. doi: 10.1093/cvr/cvab242

PMCID:: PMC9239580

Abstract Article PDF–1.9M

Select item 919001715.

Palmitoylation of the small GTPase Cdc42 by DHHC5 modulates spine formation and gene transcription

Alexander Wirth, Josephine Labus, Dalia Abdel Galil, Yvonne Schill, Silke Schmidt, Tania Bunke, Nataliya Gorinski, Norihiko Yokoi, Masaki Fukata, Evgeni Ponimaskin

J Biol Chem. 2022 Jun; 298(6): 102048. Published online 2022 May 18. doi: 10.1016/j.jbc.2022.102048

PMCID:: PMC9190017

Abstract Article PDF–1.6M

Select item 912430016.

Regulation of Cdc42 signaling by the dopamine D2 receptor in a mouse model of Parkinson’s disease

Li Ying, Jinlan Zhao, Yingshan Ye, Yutong Liu, Bin Xiao, Tao Xue, Hangfei Zhu, Yue Wu, Jing He, Sifei Qin, Yong Jiang, Fukun Guo, Lin Zhang, Nuyun Liu, Lu Zhang

Aging Cell. 2022 May; 21(5): e13588. Published online 2022 Apr 12. doi: 10.1111/acel.13588

PMCID:: PMC9124300

Abstract Article PDF–6.5M

Select item 901474717.

Inactivating Celsr2 promotes motor axon fasciculation and regeneration in mouse and human

Quan Wen, Huandi Weng, Tao Liu, Lingtai Yu, Tianyun Zhao, Jingwen Qin, Si Li, Qingfeng Wu, Fadel Tissir, Yibo Qu, Libing Zhou

Brain. 2022 Feb; 145(2): 670–683. Published online 2022 Jan 4. doi: 10.1093/brain/awab317

PMCID:: PMC9014747

Abstract Article PDF–2.3M

Select item 882649318.

CDC42 controlled apical-basal polarity regulates intestinal stem cell to transit amplifying cell fate transition via YAP-EGF-mTOR signaling

Zheng Zhang, Feng Zhang, Ashley Kuenzi Davis, Mei Xin, Gerd Walz, Weidong Tian, Yi Zheng

Cell Rep. Author manuscript; available in PMC 2022 Feb 9.

Published in final edited form as: Cell Rep. 2022 Jan 11; 38(2): 110009. doi: 10.1016/j.celrep.2021.110009

PMCID:: PMC8826493

Abstract Article PDF–3.6M

Select item 864714419.

Cdc42‐Borg4‐Septin7 axis regulates HSC polarity and function

Ravinder Kandi, Katharina Senger, Ani Grigoryan, Karin Soller, Vadim Sakk, Tanja Schuster, Karina Eiwen, Manoj B Menon, Matthias Gaestel, Yi Zheng, Maria Carolina Florian, Hartmut Geiger

EMBO Rep. 2021 Dec 6; 22(12): e52931. Published online 2021 Oct 18. doi: 10.15252/embr.202152931

PMCID:: PMC8647144

Abstract Article PDF–3.0M

Select item 860408120.

Cdc42 activity in Sertoli cells is essential for maintenance of spermatogenesis

Anna Heinrich, Bidur Bhandary, Sarah J. Potter, Nancy Ratner, Tony DeFalco

Cell Rep. Author manuscript; available in PMC 2021 Nov 19.

Published in final edited form as: Cell Rep. 2021 Oct 26; 37(4): 109885. doi: 10.1016/j.celrep.2021.109885

PMCID:: PMC8604081

Abstract Article PDF–2.2M

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