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Items: 1 to 20 of 41

1.
mTOR and S6K1 drive polycystic kidney by the control of Afadin-dependent oriented cell division
Martina Bonucci, Nicolas Kuperwasser, Serena Barbe, Vonda Koka, Delphine de Villeneuve, Chi Zhang, Nishit Srivastava, Xiaoying Jia, Matthew P. Stokes, Frank Bienaimé, Virginie Verkarre, Jean Baptiste Lopez, Fanny Jaulin, Marco Pontoglio, Fabiola Terzi, Benedicte Delaval, Matthieu Piel, Mario Pende
Nat Commun. 2020; 11: 3200. Published online 2020 Jun 24. doi: 10.1038/s41467-020-16978-z
PMCID:
PMC7314806
AbstractArticlePDF–6.6M
2.
Balanced mTORC1 Activity in Oligodendrocytes Is Required for Accurate CNS Myelination
Frédéric Lebrun-Julien, Lea Bachmann, Camilla Norrmén, Martin Trötzmüller, Harald Köfeler, Markus A. Rüegg, Michael N. Hall, Ueli Suter
J Neurosci. 2014 Jun 18; 34(25): 8432–8448. doi: 10.1523/JNEUROSCI.1105-14.2014
PMCID:
PMC6608214
AbstractArticlePDF–6.0M
3.
PKA-Dependent Phosphorylation of Ribosomal Protein S6 Does Not Correlate with Translation Efficiency in Striatonigral and Striatopallidal Medium-Sized Spiny Neurons
Anne Biever, Emma Puighermanal, Akinori Nishi, Alexandre David, Claire Panciatici, Sophie Longueville, Dimitris Xirodimas, Giuseppe Gangarossa, Oded Meyuhas, Denis Hervé, Jean-Antoine Girault, Emmanuel Valjent
J Neurosci. 2015 Mar 11; 35(10): 4113–4130. doi: 10.1523/JNEUROSCI.3288-14.2015
PMCID:
PMC6605295
AbstractArticlePDF–8.4M
4.
mTOR regulates metabolic adaptation of APCs in the lung and controls the outcome of allergic inflammation
Charles Sinclair, Gayathri Bommakanti, Luiz Gardinassi, Jens Loebbermann, Matthew Joseph Johnson, Paul Hakimpour, Thomas Hagan, Lydia Benitez, Andrei Todor, Deepa Machiah, Timothy Oriss, Anuradha Ray, Steven Bosinger, Rajesh Ravindran, Shuzhao Li, Bali Pulendran
Science. Author manuscript; available in PMC 2018 Sep 8.
Published in final edited form as: Science. 2017 Sep 8; 357(6355): 1014–1021. Published online 2017 Aug 10. doi: 10.1126/science.aaj2155
PMCID:
PMC5746055
AbstractArticlePDF–1.8M
5.
Epiregulin and EGFR interactions are involved in pain processing
Loren J. Martin, Shad B. Smith, Arkady Khoutorsky, Claire A. Magnussen, Alexander Samoshkin, Robert E. Sorge, Chulmin Cho, Noosha Yosefpour, Sivaani Sivaselvachandran, Sarasa Tohyama, Tiffany Cole, Thang M. Khuong, Ellen Mir, Dustin G. Gibson, Jeffrey S. Wieskopf, Susana G. Sotocinal, Jean Sebastien Austin, Carolina B. Meloto, Joseph H. Gitt, Christos Gkogkas, Nahum Sonenberg, Joel D. Greenspan, Roger B. Fillingim, Richard Ohrbach, Gary D. Slade, Charles Knott, Ronald Dubner, Andrea G. Nackley, Alfredo Ribeiro-da-Silva, G. Gregory Neely, William Maixner, Dmitri V. Zaykin, Jeffrey S. Mogil, Luda Diatchenko
J Clin Invest. 2017 Sep 1; 127(9): 3353–3366. Published online 2017 Aug 7. doi: 10.1172/JCI87406
PMCID:
PMC5669538
AbstractArticlePDF–1.3M
6.
ZRF1 is a novel S6 kinase substrate that drives the senescence programme
Manuela Barilari, Gregory Bonfils, Caroline Treins, Vonda Koka, Delphine De Villeneuve, Sylvie Fabrega, Mario Pende
EMBO J. 2017 Mar 15; 36(6): 736–750. Published online 2017 Feb 27. doi: 10.15252/embj.201694966
PMCID:
PMC5350561
AbstractArticlePDF–2.2M
7.
Unique and Redundant Functions of p70 Ribosomal S6 Kinase Isoforms Regulate Mesenchymal Cell Proliferation and Migration in Pulmonary Fibrosis
Satish K. Madala, Vishwaraj Sontake, Ramakrishna Edukulla, Cynthia R. Davidson, Stephanie Schmidt, William D. Hardie
Am J Respir Cell Mol Biol. 2016 Dec; 55(6): 792–803. doi: 10.1165/rcmb.2016-0090OC
PMCID:
PMC5248954
AbstractArticlePDF–1.9M
8.
Context-specific function of S6K2 in helper T cell differentiation
Christine Pai, Craig M. Walsh, David A. Fruman
J Immunol. Author manuscript; available in PMC 2017 Oct 15.
Published in final edited form as: J Immunol. 2016 Oct 15; 197(8): 3049–3058. Published online 2016 Sep 9. doi: 10.4049/jimmunol.1600167
PMCID:
PMC5101169
AbstractArticlePDF–1.8M
9.
The 4E-BP–eIF4E axis promotes rapamycin-sensitive growth and proliferation in lymphocytes
Lomon So, Jongdae Lee, Miguel Palafox, Sharmila Mallya, Chaz G. Woxland, Meztli Arguello, Morgan L. Truitt, Nahum Sonenberg, Davide Ruggero, David A. Fruman
Sci Signal. Author manuscript; available in PMC 2016 Nov 30.
Published in final edited form as: Sci Signal. 2016; 9(430): ra57. Published online 2016 May 31. doi: 10.1126/scisignal.aad8463
PMCID:
PMC4924540
AbstractArticlePDF–1.0M
10.
S6K-STING interaction regulates cytosolic DNA-mediated activation of the transcription factor IRF3
Fuan Wang, Tommy Alain, Kristy J. Szretter, Kyle Stephenson, Jonathan G. Pol, Matthew J. Atherton, Huy-Dung Hoang, Bruno D. Fonseca, Chadi Zakaria, Lan Chen, Zainab Rangwala, Adam Hesch, Eva Sin Yan Chan, Carly Tuinman, Mehul S. Suthar, Zhaozhao Jiang, Ali A. Ashkar, George Thomas, Sara C. Kozma, Michael Gale, Jr, Katherine A. Fitzgerald, Michael S. Diamond, Karen Mossman, Nahum Sonenberg, Yonghong Wan, Brian D. Lichty
Nat Immunol. Author manuscript; available in PMC 2017 May 1.
Published in final edited form as: Nat Immunol. 2016 May; 17(5): 514–522. Published online 2016 Apr 4. doi: 10.1038/ni.3433
PMCID:
PMC4917298
AbstractArticlePDF–2.9M
11.
Analysis of a lung defect in autophagy-deficient mouse strains
Heesun Cheong, Junmin Wu, Linda K Gonzales, Susan H Guttentag, Craig B Thompson, Tullia Lindsten
Autophagy. 2014 Jan 1; 10(1): 45–56. Published online 2013 Nov 11. doi: 10.4161/auto.26505
PMCID:
PMC4028323
AbstractArticlePDF–2.9M
12.
Toll-like receptor–mediated induction of type I interferon in plasmacytoid dendritic cells requires the rapamycin-sensitive PI(3)K-mTOR-p70S6K pathway
Weiping Cao, Santhakumar Manicassamy, Hua Tang, Sudhir Pai Kasturi, Ali Pirani, Niren Murthy, Bali Pulendran
Nat Immunol. Author manuscript; available in PMC 2013 Aug 3.
Published in final edited form as: Nat Immunol. 2008 Oct; 9(10): 1157–1164. Published online 2008 Aug 31. doi: 10.1038/ni.1645
PMCID:
PMC3732485
AbstractArticlePDF–2.6M
13.
The mTOR pathway negatively controls ATM by up-regulating miRNAs
Changxian Shen, Peter J. Houghton
Proc Natl Acad Sci U S A. 2013 Jul 16; 110(29): 11869–11874. Published online 2013 Jul 1. doi: 10.1073/pnas.1220898110
PMCID:
PMC3718104
AbstractArticlePDF–603K
14.
Dysregulation of Multiple Facets of Glycogen Metabolism in a Murine Model of Pompe Disease
Kristin M. Taylor, Elizabeth Meyers, Michael Phipps, Priya S. Kishnani, Seng H. Cheng, Ronald K. Scheule, Rodney J. Moreland
PLoS One. 2013; 8(2): e56181. Published online 2013 Feb 14. doi: 10.1371/journal.pone.0056181
PMCID:
PMC3572993
AbstractArticlePDF–1.0M
15.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
16.
Regulatory Effects of Programmed Cell Death 4 (PDCD4) Protein in Interferon (IFN)-Stimulated Gene Expression and Generation of Type I IFN Responses
Barbara Kroczynska, Bhumika Sharma, Elizabeth A. Eklund, Eleanor N. Fish, Leonidas C. Platanias
Mol Cell Biol. 2012 Jul; 32(14): 2809–2822. doi: 10.1128/MCB.00310-12
Correction in:
Mol Cell Biol. 2012 Sep; 32(17): 3608.
PMCID:
PMC3416205
AbstractArticlePDF–2.2M
17.
Follistatin-mediated skeletal muscle hypertrophy is regulated by Smad3 and mTOR independently of myostatin
Catherine E. Winbanks, Kate L. Weeks, Rachel E. Thomson, Patricio V. Sepulveda, Claudia Beyer, Hongwei Qian, Justin L. Chen, James M. Allen, Graeme I. Lancaster, Mark A. Febbraio, Craig A. Harrison, Julie R. McMullen, Jeffrey S. Chamberlain, Paul Gregorevic
J Cell Biol. 2012 Jun 25; 197(7): 997–1008. doi: 10.1083/jcb.201109091
PMCID:
PMC3384410
AbstractArticlePDF–2.4M
18.
Metabolic Control by S6 Kinases Depends on Dietary Lipids
Tamara R. Castañeda, William Abplanalp, Sung Hee Um, Paul T. Pfluger, Brigitte Schrott, Kimberly Brown, Erin Grant, Larissa Carnevalli, Stephen C. Benoit, Donald A. Morgan, Dean Gilham, David Y. Hui, Kamal Rahmouni, George Thomas, Sara C. Kozma, Deborah J. Clegg, Matthias H. Tschöp
PLoS One. 2012; 7(3): e32631. Published online 2012 Mar 7. doi: 10.1371/journal.pone.0032631
PMCID:
PMC3296718
AbstractArticlePDF–802K
19.
S6 kinase 1 is required for rapamycin-sensitive liver proliferation after mouse hepatectomy
Catherine Espeillac, Claudia Mitchell, Séverine Celton-Morizur, Céline Chauvin, Vonda Koka, Cynthia Gillet, Jeffrey H. Albrecht, Chantal Desdouets, Mario Pende
J Clin Invest. 2011 Jul 1; 121(7): 2821–2832. Published online 2011 Jun 1. doi: 10.1172/JCI44203
PMCID:
PMC3223822
AbstractArticlePDF–3.5M
20.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M

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