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Select item 72896001.

Signaling diversity enabled by Rap1-regulated plasma membrane ERK with distinct temporal dynamics

Jeremiah Keyes, Ambhighainath Ganesan, Olivia Molinar-Inglis, Archer Hamidzadeh, Jinfan Zhang, Megan Ling, JoAnn Trejo, Andre Levchenko, Jin Zhang

eLife. 2020; 9: e57410. Published online 2020 May 26. doi: 10.7554/eLife.57410

PMCID:: PMC7289600

Abstract Article PDF–1.5M

Select item 66056272.

Rap1 regulates hepatic stellate cell migration through the modulation of RhoA activity in response to TGF-β1

Mi-Young Moon, Hee-Jun Kim, Mo-Jong Kim, Sunho Uhm, Ji-Won Park, Ki-Tae Suk, Jae-Bong Park, Dong-Jun Kim, Sung-Eun Kim

Int J Mol Med. 2019 Aug; 44(2): 491–502. Published online 2019 May 30. doi: 10.3892/ijmm.2019.4215

PMCID:: PMC6605627

Abstract Article PDF–1.3M

Select item 45873273.

Sequential Elution Interactome Analysis of the Mind Bomb 1 Ubiquitin Ligase Reveals a Novel Role in Dendritic Spine Outgrowth

Joseph Mertz, Haiyan Tan, Vishwajeeth Pagala, Bing Bai, Ping-Chung Chen, Yuxin Li, Ji-Hoon Cho, Timothy Shaw, Xusheng Wang, Junmin Peng

Mol Cell Proteomics. 2015 Jul; 14(7): 1898–1910. Published online 2015 Apr 30. doi: 10.1074/mcp.M114.045898

PMCID:: PMC4587327

Abstract Article PDF–2.6M

Select item 43352304.

Phosphorylation of Synaptic GTPase-activating Protein (synGAP) by Ca²⁺/Calmodulin-dependent Protein Kinase II (CaMKII) and Cyclin-dependent Kinase 5 (CDK5) Alters the Ratio of Its GAP Activity toward Ras and Rap GTPases

Ward G. Walkup, IV, Lorraine Washburn, Michael J. Sweredoski, Holly J. Carlisle, Robert L. Graham, Sonja Hess, Mary B. Kennedy

J Biol Chem. 2015 Feb 20; 290(8): 4908–4927. Published online 2014 Dec 22. doi: 10.1074/jbc.M114.614420

PMCID:: PMC4335230

Abstract Article PDF–3.0M

Select item 41143465.

Cyclic nucleotide phosphodiesterase 1A: a key regulator of cardiac fibroblast activation and extracellular matrix remodeling in the heart

Clint L. Miller, Yujun Cai, Masayoshi Oikawa, Tamlyn Thomas, Wolfgang R. Dostmann, Manuela Zaccolo, Keigi Fujiwara, Chen Yan

Basic Res Cardiol. Author manuscript; available in PMC 2014 Jul 29.

Published in final edited form as: Basic Res Cardiol. 2011 Nov; 106(6): 1023–1039. Published online 2011 Oct 20. doi: 10.1007/s00395-011-0228-2

PMCID:: PMC4114346

Abstract Article PDF–2.0M

Select item 39537476.

Interactome analysis of AMP-activated protein kinase (AMPK)-α1 and -β1 in INS-1 pancreatic beta-cells by affinity purification-mass spectrometry

Sungyoon Moon, Dohyun Han, Yikwon Kim, Jonghwa Jin, Won-Kyung Ho, Youngsoo Kim

Sci Rep. 2014; 4: 4376. Published online 2014 Mar 14. doi: 10.1038/srep04376

PMCID:: PMC3953747

Abstract Article PDF–1.4M

Select item 36577277.

Rap1 Signaling Prevents L-Type Calcium Channel-Dependent Neurotransmitter Release

Jaichandar Subramanian, Louis Dye, Alexei Morozov

J Neurosci. 2013 Apr 24; 33(17): 7245–7252. doi: 10.1523/JNEUROSCI.5963-11.2013

PMCID:: PMC3657727

Abstract Article PDF–3.1M

Select item 36286968.

Analysis of oxygen/glucose-deprivation-induced changes in SUMO3 conjugation using SILAC-based quantitative proteomics

Wei Yang, J. Will Thompson, Zhengfeng Wang, Liangli Wang, Huaxin Sheng, Matthew W. Foster, M. Arthur Moseley, Wulf Paschen

J Proteome Res. Author manuscript; available in PMC 2013 Apr 17.

Published in final edited form as: J Proteome Res. 2012 Feb 3; 11(2): 1108–1117. Published online 2011 Dec 1. doi: 10.1021/pr200834f

PMCID:: PMC3628696

Abstract Article PDF–1.3M

Select item 35182199.

KIF14 negatively regulates Rap1a–Radil signaling during breast cancer progression

Syed M. Ahmed, Brigitte L. Thériault, Maruti Uppalapati, Catherine W.N. Chiu, Brenda L. Gallie, Sachdev S. Sidhu, Stéphane Angers

J Cell Biol. 2012 Dec 10; 199(6): 951–967. doi: 10.1083/jcb.201206051

PMCID:: PMC3518219

Abstract Article PDF–3.7M

Select item 347302310.

Apocynin-Treatment Reverses Hyperoxaluria Induced Changes in NADPH Oxidase System Expression in Rat Kidneys: A Transcriptional Study

Sunil Joshi, Benjamin T. Saylor, Wei Wang, Ammon B. Peck, Saeed R. Khan

PLoS One. 2012; 7(10): e47738. Published online 2012 Oct 16. doi: 10.1371/journal.pone.0047738

PMCID:: PMC3473023

Abstract Article PDF–779K

Select item 321030011.

Rap1GAP impairs cell-matrix adhesion in the absence of effects on cell-cell adhesion

Lisa A Vuchak, Oxana M Tsygankova, Judy L Meinkoth

Cell Adh Migr. 2011 Jul-Aug; 5(4): 323–331. Published online 2011 Jul 1. doi: 10.4161/cam.5.4.17041

PMCID:: PMC3210300

Abstract Article PDF–1.3M

Select item 317805912.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 308951013.

The cAMP-responsive Rap1 Guanine Nucleotide Exchange Factor, Epac, Induces Smooth Muscle Relaxation by Down-regulation of RhoA Activity

Bartosz J. Zieba, Mykhaylo V. Artamonov, Li Jin, Ko Momotani, Ruoya Ho, Aaron S. Franke, Ronald L. Neppl, Andra S. Stevenson, Alexander S. Khromov, Magdalena Chrzanowska-Wodnicka, Avril V. Somlyo

J Biol Chem. 2011 May 13; 286(19): 16681–16692. Published online 2011 Mar 25. doi: 10.1074/jbc.M110.205062

PMCID:: PMC3089510

Abstract Article PDF–1.9M

Select item 307755714.

Rap1 Activation Is Required for Fcγ Receptor-Dependent Phagocytosis

Jooho Chung, Carlos H. Serezani, Steven K. Huang, Joel N. H. Stern, Derin B. Keskin, Rajesh Jagirdar, Thomas G. Brock, David M. Aronoff, Marc Peters-Golden

J Immunol. Author manuscript; available in PMC 2011 Apr 15.

Published in final edited form as: J Immunol. 2008 Oct 15; 181(8): 5501–5509. doi: 10.4049/jimmunol.181.8.5501

PMCID:: PMC3077557

Abstract Article PDF–1016K

Select item 306973615.

New targets of urocortin-mediated cardioprotection

Seán P Barry, Kevin M Lawrence, James McCormick, Surinder M Soond, Mike Hubank, Simon Eaton, Ahila Sivarajah, Tiziano M Scarabelli, Richard A Knight, Christoph Thiemermann, David S Latchman, Paul A Townsend, Anastasis Stephanou

J Mol Endocrinol. 2010 Aug; 45(2): 69–85. Prepublished online 2010 May 25. doi: 10.1677/JME-09-0148

PMCID:: PMC3069736

Abstract Article PDF–317K

Select item 287144516.

Rap1 Promotes Multiple Pancreatic Islet Cell Functions and Signals through Mammalian Target of Rapamycin Complex 1 to Enhance Proliferation

Patrick Kelly, Candice L. Bailey, Patrick T. Fueger, Christopher B. Newgard, Patrick J. Casey, Michelle E. Kimple

J Biol Chem. 2010 May 21; 285(21): 15777–15785. Published online 2010 Mar 25. doi: 10.1074/jbc.M109.069112

PMCID:: PMC2871445

Abstract Article PDF–1.3M

Select item 267610117.

Proteolipid Protein Is Required for Transport of Sirtuin 2 into CNS Myelin

Hauke B. Werner, Katja Kuhlmann, Siming Shen, Marina Uecker, Anke Schardt, Kalina Dimova, Foteini Orfaniotou, Ajit Dhaunchak, Bastian G. Brinkmann, Wiebke Möbius, Lenny Guarente, Patrizia Casaccia-Bonnefil, Olaf Jahn, Klaus-Armin Nave

J Neurosci. 2007 Jul 18; 27(29): 7717–7730. doi: 10.1523/JNEUROSCI.1254-07.2007