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Items: 1 to 20 of 24

1.
p53 inhibitor iASPP is an unexpected suppressor of KRAS and inflammation-driven pancreatic cancer
Paul Miller, Elliot H. Akama-Garren, Richard P. Owen, Constantinos Demetriou, Thomas M. Carroll, Elizabeth Slee, Khatoun Al Moussawi, Michael Ellis, Robert Goldin, Eric O’Neill, Xin Lu
Cell Death Differ. 2023 Jul; 30(7): 1619–1635. Published online 2023 Jun 3. doi: 10.1038/s41418-023-01168-3
PMCID:
PMC10307949
AbstractArticlePDF–6.6M
2.
iASPP regulates neurite development by interacting with Spectrin proteins
Junhao Wang, Chunhong Jia, Qiong Gao, Jiwen Zhang, Xi Gu
Front Mol Neurosci. 2023; 16: 1154770. Published online 2023 May 22. doi: 10.3389/fnmol.2023.1154770
PMCID:
PMC10240065
AbstractArticlePDF–9.6M
3.
Mutant Ras and inflammation-driven skin tumorigenesis is suppressed via a JNK-iASPP-AP1 axis
Khatoun Al Moussawi, Kathryn Chung, Thomas M. Carroll, Christian Osterburg, Artem Smirnov, Rebecca Lotz, Paul Miller, Zinaida Dedeić, Shan Zhong, Martin Oti, Evelyn N. Kouwenhoven, Ruth Asher, Robert Goldin, Michael Tellier, Shona Murphy, Huiqing Zhou, Volker Dötsch, Xin Lu
Cell Rep. 2022 Oct 18; 41(3): 111503. Published online 2022 Oct 18. doi: 10.1016/j.celrep.2022.111503
PMCID:
PMC9597577
AbstractArticlePDF–8.7M
4.
The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis
Shalini Menon, Dennis Goldfarb, Chris T. Ho, Erica W. Cloer, Nicholas P. Boyer, Christopher Hardie, Andrew J. Bock, Emma C. Johnson, Joel Anil, M. Ben Major, Stephanie L. Gupton
Mol Biol Cell. 2021 Feb 15; 32(4): 314–330. doi: 10.1091/mbc.E20-10-0622
PMCID:
PMC8098814
AbstractArticlePDF–7.7M
5.
Inhibitor of apoptosis-stimulating protein of p53 inhibits ferroptosis and alleviates intestinal ischemia/reperfusion-induced acute lung injury
Yingchuan Li, Yongmei Cao, Jian Xiao, Jiawei Shang, Qin Tan, Feng Ping, Weifeng Huang, Fang Wu, Haijun Zhang, Xiaoping Zhang
Cell Death Differ. 2020 Sep; 27(9): 2635–2650. Published online 2020 Mar 18. doi: 10.1038/s41418-020-0528-x
PMCID:
PMC7429834
AbstractArticlePDF–7.2M
6.
Rearrangement of the Protein Phosphatase 1 Interactome during Heart Failure Progression
David Y. Chiang, Katherina M. Alsina, Eleonora Corradini, Martin Fitzpatrick, Li Ni, Satadru K. Lahiri, Julia Reynolds, Xiaolu Pan, Larry Scott, Jr, Albert J.R. Heck, Xander H.T. Wehrens
Circulation. Author manuscript; available in PMC 2019 Oct 9.
Published in final edited form as: Circulation. 2018 Oct 9; 138(15): 1569–1581. doi: 10.1161/CIRCULATIONAHA.118.034361
PMCID:
PMC6193872
AbstractArticlePDF–2.4M
7.
Cell autonomous role of iASPP deficiency in causing cardiocutaneous disorders
Zinaida Dedeić, Gopinath Sutendra, Ying Hu, Kathryn Chung, Elizabeth A. Slee, Michael J. White, Felix Y. Zhou, Robert D. Goldin, David J. P. Ferguson, Debra McAndrew, Jurgen E. Schneider, Xin Lu
Cell Death Differ. 2018 Jul; 25(7): 1289–1303. Published online 2018 Jan 19. doi: 10.1038/s41418-017-0039-6
PMCID:
PMC6030222
AbstractArticlePDF–4.7M
8.
Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function
Tingting Zhang, Wei Du, Andrew F. Wilson, Satoshi H. Namekawa, Paul R. Andreassen, Amom Ruhikanta Meetei, Qishen Pang
Sci Rep. 2017; 7: 45626. Published online 2017 Apr 5. doi: 10.1038/srep45626
PMCID:
PMC5381226
AbstractArticlePDF–1.4M
9.
Sequence variation in PPP1R13L results in a novel form of cardio‐cutaneous syndrome
Tzipora C Falik‐Zaccai, Yiftah Barsheshet, Hanna Mandel, Meital Segev, Avraham Lorber, Shachaf Gelberg, Limor Kalfon, Shani Ben Haroush, Adel Shalata, Liat Gelernter‐Yaniv, Sarah Chaim, Dorith Raviv Shay, Morad Khayat, Michal Werbner, Inbar Levi, Yishay Shoval, Galit Tal, Stavit Shalev, Eli Reuveni, Emily Avitan‐Hersh, Eugene Vlodavsky, Liat Appl‐Sarid, Dorit Goldsher, Reuven Bergman, Zvi Segal, Ora Bitterman‐Deutsch, Orly Avni
EMBO Mol Med. 2017 Mar; 9(3): 319–336. Published online 2017 Jan 9. doi: 10.15252/emmm.201606523
Correction in:
EMBO Mol Med. 2017 Sep; 9(9): 1326.
PMCID:
PMC5331242
AbstractArticlePDF–2.8M
10.
Cardiac disease and arrhythmogenesis: Mechanistic insights from mouse models
Lois Choy, Jie Ming Yeo, Vivian Tse, Shing Po Chan, Gary Tse
Int J Cardiol Heart Vasc. 2016 Sep; 12: 1–10. Published online 2016 May 14. doi: 10.1016/j.ijcha.2016.05.005
PMCID:
PMC5064289
AbstractArticlePDF–1011K
11.
Nuclear iASPP may facilitate prostate cancer progression
E V Morris, L Cerundolo, M Lu, C Verrill, F Fritzsche, M J White, G N Thalmann, C S ten Donkelaar, I Ratnayaka, V Salter, F C Hamdy, X Lu, R J Bryant
Cell Death Dis. 2014 Oct; 5(10): e1492. Published online 2014 Oct 23. doi: 10.1038/cddis.2014.442
PMCID:
PMC4649527
AbstractArticlePDF–14M
12.
iASPP, a previously unidentified regulator of desmosomes, prevents arrhythmogenic right ventricular cardiomyopathy (ARVC)-induced sudden death
Mario Notari, Ying Hu, Gopinath Sutendra, Zinaida Dedeić, Min Lu, Laurent Dupays, Arash Yavari, Carolyn A. Carr, Shan Zhong, Aaisha Opel, Andrew Tinker, Kieran Clarke, Hugh Watkins, David J. P. Ferguson, David P. Kelsell, Sofia de Noronha, Mary N. Sheppard, Mike Hollinshead, Timothy J. Mohun, Xin Lu
Proc Natl Acad Sci U S A. 2015 Mar 3; 112(9): E973–E981. Published online 2015 Feb 17. doi: 10.1073/pnas.1408111112
PMCID:
PMC4352828
AbstractArticlePDF–2.2M
13.
Waved with open eyelids 2 (woe2) is a novel spontaneous mouse mutation in the protein phosphatase 1, regulatory (inhibitor) subunit 13 like (Ppp1r13l) gene
Joseph Toonen, Lina Liang, Duska J Sidjanin
BMC Genet. 2012; 13: 76. Published online 2012 Aug 28. doi: 10.1186/1471-2156-13-76
PMCID:
PMC3469352
AbstractArticlePDF–1.5M
14.
A distinct response to endogenous DNA damage in the development of Nbs1-deficient cortical neurons
Rui Li, Yun-Gui Yang, Yunzhou Gao, Zhao-Qi Wang, Wei-Min Tong
Cell Res. 2012 May; 22(5): 859–872. Published online 2012 Jan 3. doi: 10.1038/cr.2012.3
PMCID:
PMC3343649
AbstractArticlePDF–2.1M
15.
Enforced Expression of PPP1R13L Increases Tumorigenesis and Invasion Through p53-Dependent and p53-Independent Mechanisms
Magdalena J. Laska, Scott W. Lowe, Lars Zender, Stephen Hearn, Ulla Vogel, Uffe B. Jensen, Anka Bric, Bjørn A. Nexø
Mol Carcinog. Author manuscript; available in PMC 2012 Apr 17.
Published in final edited form as: Mol Carcinog. 2009 Sep; 48(9): 832–842. doi: 10.1002/mc.20528
PMCID:
PMC3328301
AbstractArticlePDF–6.7M
16.
iASPP/p63 autoregulatory feedback loop is required for the homeostasis of stratified epithelia
Anissa Chikh, Rubeta N H Matin, Valentina Senatore, Martin Hufbauer, Danielle Lavery, Claudio Raimondi, Paola Ostano, Maurizia Mello-Grand, Chiara Ghimenti, Adiam Bahta, Sahira Khalaf, Baki Akgül, Kristin M Braun, Giovanna Chiorino, Michael P Philpott, Catherine A Harwood, Daniele Bergamaschi
EMBO J. 2011 Oct 19; 30(20): 4261–4273. Published online 2011 Sep 6. doi: 10.1038/emboj.2011.302
PMCID:
PMC3199390
AbstractArticlePDF–2.0M
17.
Inhibitor of apoptosis-stimulating protein of p53 (iASPP) prevents senescence and is required for epithelial stratification
Mario Notari, Ying Hu, Sofia Koch, Min Lu, Indrika Ratnayaka, Shan Zhong, Caroline Baer, Anna Pagotto, Robert Goldin, Victoria Salter, Eleonora Candi, Gerry Melino, Xin Lu
Proc Natl Acad Sci U S A. 2011 Oct 4; 108(40): 16645–16650. Published online 2011 Sep 19. doi: 10.1073/pnas.1102292108
PMCID:
PMC3189025
AbstractArticlePDF–1.4M
18.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
19.
A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo
Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio
PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582
PMCID:
PMC3022534
AbstractArticlePDF–3.8M
20.
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells
Gwenn M. Hansen, Diane C. Markesich, Michael B. Burnett, Qichao Zhu, Karen M. Dionne, Lizabeth J. Richter, Richard H. Finnell, Arthur T. Sands, Brian P. Zambrowicz, Alejandro Abuin
Genome Res. 2008 Oct; 18(10): 1670–1679. doi: 10.1101/gr.078352.108
PMCID:
PMC2556270
AbstractArticlePDF–493K

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