PMC Links for GEO Profiles (Select 28824740) - PMC

Athea Vichas, Amanda K. Riley, Naomi T. Nkinsi, Shriya Kamlapurkar, Phoebe C. R. Parrish, April Lo, Fujiko Duke, Jennifer Chen, Iris Fung, Jacqueline Watson, Matthew Rees, Austin M. Gabel, James D. Thomas, Robert K. Bradley, John K. Lee, Emily M. Hatch, Marina K. Baine, Natasha Rekhtman, Marc Ladanyi, Federica Piccioni, Alice H. Berger

Nat Commun. 2021; 12: 4789. Published online 2021 Aug 9. doi: 10.1038/s41467-021-24841-y

PMCID:: PMC8352964

Abstract Article PDF–4.5M

Select item 77580504.

In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators

Jennifer L. Franks, Raquel C. Martinez-Chacin, Xianxi Wang, Rochelle L. Tiedemann, Thomas Bonacci, Rajarshi Choudhury, Derek L. Bolhuis, Taylor P. Enrico, Ryan D. Mouery, Jeffrey S. Damrauer, Feng Yan, Joseph S. Harrison, M. Ben Major, Katherine A. Hoadley, Aussie Suzuki, Scott B. Rothbart, Nicholas G. Brown, Michael J. Emanuele

PLoS Biol. 2020 Dec; 18(12): e3000975. Published online 2020 Dec 11. doi: 10.1371/journal.pbio.3000975

PMCID:: PMC7758050

Abstract Article PDF–4.2M

Select item 75826415.

What Role Does COA6 Play in Cytochrome C Oxidase Biogenesis: A Metallochaperone or Thiol Oxidoreductase, or Both?

Shadi Maghool, Michael T. Ryan, Megan J. Maher

Int J Mol Sci. 2020 Oct; 21(19): 6983. Published online 2020 Sep 23. doi: 10.3390/ijms21196983

PMCID:: PMC7582641

Abstract Article PDF–1.5M

Select item 75668816.

Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism

Michael Aregger, Keith A. Lawson, Maximillian Billmann, Michael Costanzo, Amy H. Y. Tong, Katherine Chan, Mahfuzur Rahman, Kevin R. Brown, Catherine Ross, Matej Usaj, Lucy Nedyalkova, Olga Sizova, Andrea Habsid, Judy Pawling, Zhen-Yuan Lin, Hala Abdouni, Cassandra J. Wong, Alexander Weiss, Patricia Mero, James W. Dennis, Anne-Claude Gingras, Chad L. Myers, Brenda J. Andrews, Charles Boone, Jason Moffat

Nat Metab. Author manuscript; available in PMC 2020 Dec 1.

Published in final edited form as: Nat Metab. 2020 Jun; 2(6): 499–513. Published online 2020 Jun 1. doi: 10.1038/s42255-020-0211-z

PMCID:: PMC7566881

Abstract Article PDF–4.8M

Select item 74847597.

CHIP ubiquitylates NOXA and induces its lysosomal degradation in response to DNA damage

Marie-Christine Albert, Kerstin Brinkmann, Wojciech Pokrzywa, Saskia Diana Günther, Martin Krönke, Thorsten Hoppe, Hamid Kashkar

Cell Death Dis. 2020 Sep; 11(9): 740. Published online 2020 Sep 10. doi: 10.1038/s41419-020-02923-x

PMCID:: PMC7484759

Abstract Article PDF–2.6M

Select item 72540628.

COA6 Facilitates Cytochrome c Oxidase Biogenesis as Thiol-reductase for Copper Metallochaperones in Mitochondria

David Pacheu-Grau, Michał Wasilewski, Silke Oeljeklaus, Christine Silvia Gibhardt, Abhishek Aich, Margarita Chudenkova, Sven Dennerlein, Markus Deckers, Ivan Bogeski, Bettina Warscheid, Agnieszka Chacinska, Peter Rehling

J Mol Biol. 2020 Mar 27; 432(7): 2067–2079. doi: 10.1016/j.jmb.2020.01.036

PMCID:: PMC7254062

Abstract Article

Select item 71699839.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 694659710.

COA6 Is Structurally Tuned to Function as a Thiol-Disulfide Oxidoreductase in Copper Delivery to Mitochondrial Cytochrome c Oxidase

Shivatheja Soma, Marcos N. Morgada, Mandar T. Naik, Aren Boulet, Anna A. Roesler, Nathaniel Dziuba, Alok Ghosh, Qinhong Yu, Paul A. Lindahl, James B. Ames, Scot C. Leary, Alejandro J. Vila, Vishal M. Gohil

Cell Rep. Author manuscript; available in PMC 2020 Jan 7.

Published in final edited form as: Cell Rep. 2019 Dec 17; 29(12): 4114–4126.e5. doi: 10.1016/j.celrep.2019.11.054

PMCID:: PMC6946597

Abstract Article PDF–1.9M

Select item 683185111.

Rewiring of the Human Mitochondrial Interactome during Neuronal Reprogramming Reveals Regulators of the Respirasome and Neurogenesis

Mohamed Taha Moutaoufik, Ramy Malty, Shahreen Amin, Qingzhou Zhang, Sadhna Phanse, Alla Gagarinova, Mara Zilocchi, Larissa Hoell, Zoran Minic, Maria Gagarinova, Hiroyuki Aoki, Jocelyn Stockwell, Matthew Jessulat, Florian Goebels, Kirsten Broderick, Nichollas E. Scott, James Vlasblom, Gabriel Musso, Bhanu Prasad, Eleonora Lamantea, Barbara Garavaglia, Alex Rajput, Kei Murayama, Yasushi Okazaki, Leonard J. Foster, Gary D. Bader, Francisco S. Cayabyab, Mohan Babu

iScience. 2019 Sep 27; 19: 1114–1132. Published online 2019 Sep 4. doi: 10.1016/j.isci.2019.08.057

PMCID:: PMC6831851

Abstract Article PDF–9.8M

Select item 674306512.

Structural and functional characterization of the mitochondrial complex IV assembly factor Coa6

Shadi Maghool, N Dinesha G Cooray, David A Stroud, David Aragão, Michael T Ryan, Megan J Maher

Life Sci Alliance. 2019 Oct; 2(5): e201900458. Published online 2019 Sep 12. doi: 10.26508/lsa.201900458

PMCID:: PMC6743065

Abstract Article PDF–1.7M

Select item 596587213.

Alterations in the brain interactome of the intrinsically disordered N-terminal domain of the cellular prion protein (PrP^C) in Alzheimer’s disease

Sarah Ulbrich, Petra Janning, Ralf Seidel, Jakob Matschke, Anika Gonsberg, Sebastian Jung, Markus Glatzel, Martin Engelhard, Konstanze F. Winklhofer, Jörg Tatzelt

PLoS One. 2018; 13(5): e0197659. Published online 2018 May 23. doi: 10.1371/journal.pone.0197659

PMCID:: PMC5965872

Abstract Article PDF–2.4M

Select item 586483214.

An AP-MS- and BioID-compatible MAC-tag enables comprehensive mapping of protein interactions and subcellular localizations

Xiaonan Liu, Kari Salokas, Fitsum Tamene, Yaming Jiu, Rigbe G. Weldatsadik, Tiina Öhman, Markku Varjosalo

Nat Commun. 2018; 9: 1188. Published online 2018 Mar 22. doi: 10.1038/s41467-018-03523-2

PMCID:: PMC5864832

Abstract Article PDF–4.5M

Select item 580914415.

COX16 promotes COX2 metallation and assembly during respiratory complex IV biogenesis

Abhishek Aich, Cong Wang, Arpita Chowdhury, Christin Ronsör, David Pacheu-Grau, Ricarda Richter-Dennerlein, Sven Dennerlein, Peter Rehling

eLife. 2018; 7: e32572. Published online 2018 Jan 30. doi: 10.7554/eLife.32572

PMCID:: PMC5809144

Abstract Article PDF–3.5M

Select item 576422616.

The mitochondrial TMEM177 associates with COX20 during COX2 biogenesis

Isotta Lorenzi, Silke Oeljeklaus, Abhishek Aich, Christin Ronsör, Sylvie Callegari, Jan Dudek, Bettina Warscheid, Sven Dennerlein, Peter Rehling

Biochim Biophys Acta. 2018 Feb; 1865(2): 323–333. doi: 10.1016/j.bbamcr.2017.11.010

PMCID:: PMC5764226

Abstract Article

Select item 542725917.

Human mitochondrial cytochrome c oxidase assembly factor COX18 acts transiently as a membrane insertase within the subunit 2 maturation module

Myriam Bourens, Antoni Barrientos

J Biol Chem. 2017 May 12; 292(19): 7774–7783. Published online 2017 Mar 22. doi: 10.1074/jbc.M117.778514

PMCID:: PMC5427259

Abstract Article PDF–1.5M

Select item 528638018.

The pseudophosphatase STYX targets the F‐box of FBXW7 and inhibits SCF^FBXW7 function

Veronika Reiterer, Cristina Figueras‐Puig, Francois Le Guerroue, Stefano Confalonieri, Manuela Vecchi, Dasaradha Jalapothu, Sandip M Kanse, Raymond J Deshaies, Pier Paolo Di Fiore, Christian Behrends, Hesso Farhan

EMBO J. 2017 Feb 1; 36(3): 260–273. Published online 2016 Dec 22. doi: 10.15252/embj.201694795

Correction in:: EMBO J. 2018 Mar 15; 37(6): e99170.

PMCID:: PMC5286380

Abstract Article PDF–2.4M

Select item 404931119.

Copper supplementation restores cytochrome c oxidase assembly defect in a mitochondrial disease model of COA6 deficiency

Alok Ghosh, Prachi P. Trivedi, Shrishiv A. Timbalia, Aaron T. Griffin, Jennifer J. Rahn, Sherine S. L. Chan, Vishal M. Gohil

Hum Mol Genet. 2014 Jul 1; 23(13): 3596–3606. Published online 2014 Feb 18. doi: 10.1093/hmg/ddu069

PMCID:: PMC4049311

Abstract Article PDF–770K

Select item 352380520.

Molecular Diagnosis of Infantile Mitochondrial Disease with Targeted Next-Generation Sequencing

Sarah E. Calvo, Alison G. Compton, Steven G. Hershman, Sze Chern Lim, Daniel S. Lieber, Elena J. Tucker, Adrienne Laskowski, Caterina Garone, Shangtao Liu, David B. Jaffe, John Christodoulou, Janice M. Fletcher, Damien L Bruno, Jack Goldblatt, Salvatore DiMauro, David R. Thorburn, Vamsi K. Mootha

Sci Transl Med. Author manuscript; available in PMC 2012 Dec 17.

Published in final edited form as: Sci Transl Med. 2012 Jan 25; 4(118): 118ra10. doi: 10.1126/scitranslmed.3003310

PMCID:: PMC3523805

Abstract Article PDF–1.7M

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