PMC Links for GEO Profiles (Select 28823145) - PMC

Select item 64418681.

POH1 contributes to hyperactivation of TGF-β signaling and facilitates hepatocellular carcinoma metastasis through deubiquitinating TGF-β receptors and caveolin-1

Boshi Wang, Xiaoli Xu, Zhaojuan Yang, Li Zhang, Yun Liu, Aihui Ma, Guiqin Xu, Ming Tang, Tiantian Jing, Lin Wu, Yongzhong Liu

EBioMedicine. 2019 Mar; 41: 320–332. Published online 2019 Feb 7. doi: 10.1016/j.ebiom.2019.01.058

PMCID:: PMC6441868

Abstract Article PDF–7.0M

Select item 50988332.

Are TMCs the Mechanotransduction Channels of Vertebrate Hair Cells?

David P. Corey, Jeffrey R. Holt

J Neurosci. 2016 Oct 26; 36(43): 10921–10926. doi: 10.1523/JNEUROSCI.1148-16.2016

PMCID:: PMC5098833

Abstract Article PDF–141K

Select item 42826243.

Transmembrane channel-like (TMC) genes are required for auditory and vestibular mechanosensation

Yoshiyuki Kawashima, Kiyoto Kurima, Bifeng Pan, Andrew J. Griffith, Jeffrey R. Holt

Pflugers Arch. Author manuscript; available in PMC 2016 Jan 1.

Published in final edited form as: Pflugers Arch. 2015 Jan; 467(1): 85–94. Published online 2014 Jul 31. doi: 10.1007/s00424-014-1582-3

PMCID:: PMC4282624

Abstract Article PDF–2.4M

Select item 41567174.

Tip-link protein protocadherin 15 interacts with transmembrane channel-like proteins TMC1 and TMC2

Reo Maeda, Katie S. Kindt, Weike Mo, Clive P. Morgan, Timothy Erickson, Hongyu Zhao, Rachel Clemens-Grisham, Peter G. Barr-Gillespie, Teresa Nicolson

Proc Natl Acad Sci U S A. 2014 Sep 2; 111(35): 12907–12912. Published online 2014 Aug 11. doi: 10.1073/pnas.1402152111

PMCID:: PMC4156717

Abstract Article PDF–1.1M

Select item 40960765.

TMC function in hair cell transduction

Jeffrey R. Holt, Bifeng Pan, Mounir A. Koussa, Yukako Asai

Hear Res. Author manuscript; available in PMC 2015 May 1.

Published in final edited form as: Hear Res. 2014 May; 0: 17–24. Published online 2014 Jan 11. doi: 10.1016/j.heares.2014.01.001

PMCID:: PMC4096076

Abstract Article PDF–629K

Select item 40765206.

Conductance and block of hair-cell mechanotransducer channels in transmembrane channel–like protein mutants

Maryline Beurg, Kyunghee X. Kim, Robert Fettiplace

J Gen Physiol. 2014 Jul; 144(1): 55–69. doi: 10.1085/jgp.201411173

PMCID:: PMC4076520

Abstract Article PDF–2.3M

Select item 38277267.

TMC1 and TMC2 are components of the mechanotransduction channel in hair cells of the mammalian inner ear

Bifeng Pan, Gwenaelle S. Géléoc, Yukako Asai, Geoffrey C. Horwitz, Kiyoto Kurima, Kotaro Ishikawa, Yoshiyuki Kawashima, Andrew J. Griffith, Jeffrey R. Holt

Neuron. Author manuscript; available in PMC 2014 Aug 7.

Published in final edited form as: Neuron. 2013 Aug 7; 79(3): 10.1016/j.neuron.2013.06.019. Published online 2013 Jul 18. doi: 10.1016/j.neuron.2013.06.019

PMCID:: PMC3827726

Abstract Article PDF–2.9M

Select item 38133858.

The role of transmembrane channel–like proteins in the operation of hair cell mechanotransducer channels

Kyunghee X. Kim, Maryline Beurg, Carole M. Hackney, David N. Furness, Shanthini Mahendrasingam, Robert Fettiplace

J Gen Physiol. 2013 Nov; 142(5): 493–505. doi: 10.1085/jgp.201311068

PMCID:: PMC3813385

Abstract Article PDF–1.8M

Select item 35225879.

Novel Genetic Loci Identified for the Pathophysiology of Childhood Obesity in the Hispanic Population

Anthony G. Comuzzie, Shelley A. Cole, Sandra L. Laston, V. Saroja Voruganti, Karin Haack, Richard A. Gibbs, Nancy F. Butte

PLoS One. 2012; 7(12): e51954. Published online 2012 Dec 14. doi: 10.1371/journal.pone.0051954

PMCID:: PMC3522587

Abstract Article PDF–130K

Select item 322634310.

Perception of sound and gravity by TMC1 and TMC2

Xi Lin

J Clin Invest. 2011 Dec 1; 121(12): 4633–4636. Published online 2011 Nov 21. doi: 10.1172/JCI61167

PMCID:: PMC3226343

Abstract Article PDF–933K

Select item 317805911.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 304837112.

Differential Genetic Associations for Systemic Lupus Erythematosus Based on Anti–dsDNA Autoantibody Production

Sharon A. Chung, Kimberly E. Taylor, Robert R. Graham, Joanne Nititham, Annette T. Lee, Ward A. Ortmann, Chaim O. Jacob, Marta E. Alarcón-Riquelme, Betty P. Tsao, John B. Harley, Patrick M. Gaffney, Kathy L. Moser, SLEGEN, Michelle Petri, F. Yesim Demirci, M. Ilyas Kamboh, Susan Manzi, Peter K. Gregersen, Carl D. Langefeld, Timothy W. Behrens, Lindsey A. Criswell

PLoS Genet. 2011 Mar; 7(3): e1001323. Published online 2011 Mar 3. doi: 10.1371/journal.pgen.1001323

PMCID:: PMC3048371

Abstract Article PDF–622K

Select item 135612913.

Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes

Kouichi Kimura, Ai Wakamatsu, Yutaka Suzuki, Toshio Ota, Tetsuo Nishikawa, Riu Yamashita, Jun-ichi Yamamoto, Mitsuo Sekine, Katsuki Tsuritani, Hiroyuki Wakaguri, Shizuko Ishii, Tomoyasu Sugiyama, Kaoru Saito, Yuko Isono, Ryotaro Irie, Norihiro Kushida, Takahiro Yoneyama, Rie Otsuka, Katsuhiro Kanda, Takahide Yokoi, Hiroshi Kondo, Masako Wagatsuma, Katsuji Murakawa, Shinichi Ishida, Tadashi Ishibashi, Asako Takahashi-Fujii, Tomoo Tanase, Keiichi Nagai, Hisashi Kikuchi, Kenta Nakai, Takao Isogai, Sumio Sugano

Genome Res. 2006 Jan; 16(1): 55–65. doi: 10.1101/gr.4039406

PMCID:: PMC1356129

Abstract Article PDF–438K

Select item 40369714.

The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment

Hilary F. Clark, Austin L. Gurney, Evangeline Abaya, Kevin Baker, Daryl Baldwin, Jennifer Brush, Jian Chen, Bernard Chow, Clarissa Chui, Craig Crowley, Bridget Currell, Bethanne Deuel, Patrick Dowd, Dan Eaton, Jessica Foster, Christopher Grimaldi, Qimin Gu, Philip E. Hass, Sherry Heldens, Arthur Huang, Hok Seon Kim, Laura Klimowski, Yisheng Jin, Stephanie Johnson, James Lee, Lhney Lewis, Dongzhou Liao, Melanie Mark, Edward Robbie, Celina Sanchez, Jill Schoenfeld, Somasekar Seshagiri, Laura Simmons, Jennifer Singh, Victoria Smith, Jeremy Stinson, Alicia Vagts, Richard Vandlen, Colin Watanabe, David Wieand, Kathryn Woods, Ming-Hong Xie, Daniel Yansura, Sothy Yi, Guoying Yu, Jean Yuan, Min Zhang, Zemin Zhang, Audrey Goddard, William I. Wood, Paul Godowski

Genome Res. 2003 Oct; 13(10): 2265–2270. doi: 10.1101/gr.1293003