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Select item 81158901.

α3* Nicotinic Acetylcholine Receptors in the Habenula-Interpeduncular Nucleus Circuit Regulate Nicotine Intake

Karim S. Elayouby, Masago Ishikawa, Angeline J. Dukes, Alexander C. W. Smith, Qun Lu, Christie D. Fowler, Paul J. Kenny

J Neurosci. 2021 Feb 24; 41(8): 1779–1787. doi: 10.1523/JNEUROSCI.0127-19.2020

PMCID:: PMC8115890

Abstract Article PDF–1.5M

Select item 77806422.

UBXN2A regulates nicotinic receptor degradation by modulating the E3 ligase activity of CHIP

Yanfen Teng, Khosrow Rezvani, Mariella De Biasi

Biochem Pharmacol. Author manuscript; available in PMC 2021 Jan 4.

Published in final edited form as: Biochem Pharmacol. 2015 Oct 15; 97(4): 518–530. Published online 2015 Aug 8. doi: 10.1016/j.bcp.2015.08.084

PMCID:: PMC7780642

Abstract Article PDF–1.5M

Select item 67728513.

Mice Lacking Specific Nicotinic Acetylcholine Receptor Subunits Exhibit Dramatically Altered Spontaneous Activity Patterns and Reveal a Limited Role for Retinal Waves in Forming ON and OFF Circuits in the Inner Retina

Anu Bansal, Joshua H. Singer, Bryan J. Hwang, Wei Xu, Art Beaudet, Marla B. Feller

J Neurosci. 2000 Oct 15; 20(20): 7672–7681. doi: 10.1523/JNEUROSCI.20-20-07672.2000

PMCID:: PMC6772851

Abstract Article PDF–773K

Select item 67583024.

Involvement of the α3 Subunit in Central Nicotinic Binding Populations

Paul Whiteaker, Cyrus G. Peterson, Wei Xu, J. Michael McIntosh, Richard Paylor, Arthur L. Beaudet, Allan C. Collins, Michael J. Marks

J Neurosci. 2002 Apr 1; 22(7): 2522–2529. doi: 10.1523/JNEUROSCI.22-07-02522.2002

PMCID:: PMC6758302

Abstract Article PDF–620K

Select item 67256605.

A Null Mutation for the α3 Nicotinic Acetylcholine (ACh) Receptor Gene Abolishes Fast Synaptic Activity in Sympathetic Ganglia and Reveals That ACh Output from Developing Preganglionic Terminals Is Regulated in an Activity-Dependent Retrograde Manner

Siamak Rassadi, Arjun Krishnaswamy, Brigitte Pié, Russell McConnell, Michele H. Jacob, Ellis Cooper

J Neurosci. 2005 Sep 14; 25(37): 8555–8566. doi: 10.1523/JNEUROSCI.1983-05.2005

PMCID:: PMC6725660

Abstract Article PDF–819K

Select item 59686256.

A Novel Tobacco Use Phenotype Suggests the 15q25 and 19q13 Loci May be Differentially Associated With Cigarettes per Day and Tobacco-Related Problems

Leah S. Richmond-Rakerd, Jacqueline M. Otto, Wendy S. Slutske, Cindy L. Ehlers, Kirk C. Wilhelmsen, Ian R. Gizer

Nicotine Tob Res. 2017 Apr 1; 19(4): 426–434. Published online 2016 Oct 17. doi: 10.1093/ntr/ntw260

PMCID:: PMC5968625

Abstract Article PDF–184K

Select item 57886517.

Study on polymorphisms in CHRNA5/CHRNA3/CHRNB4 gene cluster and the associated with the risk of non-small cell lung cancer

Yiting Sun, Jiaye Li, Chang Zheng, Baosen Zhou

Oncotarget. 2018 Jan 5; 9(2): 2435–2444. Published online 2017 Dec 20. doi: 10.18632/oncotarget.23459

PMCID:: PMC5788651

Abstract Article PDF–1.5M

Select item 54298598.

Down-regulation of cholinergic signaling in the habenula induces anhedonia-like behavior

Seungrie Han, Soo Hyun Yang, Jin Yong Kim, Seojung Mo, Esther Yang, Ki Myung Song, Byung-Joo Ham, Naguib Mechawar, Gustavo Turecki, Hyun Woo Lee, Hyun Kim

Sci Rep. 2017; 7: 900. Published online 2017 Apr 18. doi: 10.1038/s41598-017-01088-6

Correction in:: Sci Rep. 2017; 7: 17090.

PMCID:: PMC5429859

Abstract Article PDF–5.1M

Select item 45860819.

Functional Contribution of α3L8′ to the Neuronal Nicotinic α3 Receptor

Madeline Nieves-Cintrón, Daniel Caballero-Rivera, Walter I. Silva, Manuel F. Navedo, José A. Lasalde-Dominicci

J Neurosci Res. Author manuscript; available in PMC 2015 Sep 28.

Published in final edited form as: J Neurosci Res. 2008 Oct; 86(13): 2884–2894. doi: 10.1002/jnr.21749

PMCID:: PMC4586081

Abstract Article PDF–2.4M

Select item 426841010.

Inflammation-induced increase in nicotinic acetylcholine receptor current in cutaneous nociceptive DRG neurons from the adult rat

Xiulin Zhang, Kathryn M. Albers, Michael S. Gold

Neuroscience. Author manuscript; available in PMC 2016 Jan 22.

Published in final edited form as: Neuroscience. 2015 Jan 22; 0: 483–499. Published online 2014 Oct 18. doi: 10.1016/j.neuroscience.2014.10.018

PMCID:: PMC4268410

Abstract Article PDF–2.7M

Select item 416941011.

Role of Nicotine Dependence on the Relationship between Variants in the Nicotinic Receptor Genes and Risk of Lung Adenocarcinoma

Tung-Sung Tseng, Jong Y. Park, Jovanny Zabaleta, Sarah Moody-Thomas, Melinda S. Sothern, Ted Chen, David E. Evans, Hui-Yi Lin

PLoS One. 2014; 9(9): e107268. Published online 2014 Sep 18. doi: 10.1371/journal.pone.0107268

PMCID:: PMC4169410

Abstract Article PDF–452K

Select item 411989212.

Expression of Acetylcholine Receptors by Experimental Rat Renal Allografts

Marion Meixner, Srebrena Atanasova, Winfried Padberg, Veronika Grau

Biomed Res Int. 2014; 2014: 289656. Published online 2014 Jul 9. doi: 10.1155/2014/289656

PMCID:: PMC4119892

Abstract Article PDF–2.3M

Select item 401357413.

CHRNA3 Polymorphism Modifies Lung Adenocarcinoma Risk in the Chinese Han Population

Ping He, Xue-Xi Yang, Xuan-Qiu He, Jun Chen, Fen-Xia Li, Xia Gu, Ju-Hong Jiang, Hui-Ying Liang, Guang-Yu Yao, Jian-Xing He

Int J Mol Sci. 2014 Apr; 15(4): 5446–5457. Published online 2014 Mar 28. doi: 10.3390/ijms15045446

PMCID:: PMC4013574

Abstract Article PDF–1.0M

Select item 396301514.

A novel α4/7-conotoxin LvIA from Conus lividus that selectively blocks α3β2 vs. α6/α3β2β3 nicotinic acetylcholine receptors

Sulan Luo, Dongting Zhangsun, Christina I. Schroeder, Xiaopeng Zhu, Yuanyan Hu, Yong Wu, Maegan M. Weltzin, Spencer Eberhard, Quentin Kaas, David J. Craik, J. Michael McIntosh, Paul Whiteaker

FASEB J. 2014 Apr; 28(4): 1842–1853. doi: 10.1096/fj.13-244103

PMCID:: PMC3963015

Abstract Article

Select item 388826315.

Rare missense variants in CHRNB3 and CHRNA3 are associated with risk of alcohol and cocaine dependence

Gabe Haller, Manav Kapoor, John Budde, Xiaoling Xuei, Howard Edenberg, John Nurnberger, John Kramer, Andy Brooks, Jay Tischfield, Laura Almasy, Arpana Agrawal, Kathleen Bucholz, John Rice, Nancy Saccone, Laura Bierut, Alison Goate

Hum Mol Genet. 2014 Feb 1; 23(3): 810–819. Published online 2013 Sep 20. doi: 10.1093/hmg/ddt463

PMCID:: PMC3888263

Abstract Article PDF–216K

Select item 375720516.

Positional Scanning Mutagenesis of α-Conotoxin PeIA Identifies Critical Residues That Confer Potency and Selectivity for α6/α3β2β3 and α3β2 Nicotinic Acetylcholine Receptors

Arik J. Hone, Miguel Ruiz, Mick'l Scadden, Sean Christensen, Joanna Gajewiak, Layla Azam, J. Michael McIntosh

J Biol Chem. 2013 Aug 30; 288(35): 25428–25439. Published online 2013 Jul 11. doi: 10.1074/jbc.M113.482059

PMCID:: PMC3757205

Abstract Article PDF–3.9M

Select item 346359417.

Functional Polymorphisms of CHRNA3 Predict Risks of Chronic Obstructive Pulmonary Disease and Lung Cancer in Chinese

Lei Yang, Fuman Qiu, Xiaoxiao Lu, Dongsheng Huang, Guanpei Ma, Yuan Guo, Min Hu, Yumin Zhou, Mingan Pan, Yigang Tan, Haibo Zhong, Weidong Ji, Qingyi Wei, Pixin Ran, Nanshan Zhong, Yifeng Zhou, Jiachun Lu

PLoS One. 2012; 7(10): e46071. Published online 2012 Oct 3. doi: 10.1371/journal.pone.0046071

PMCID:: PMC3463594

Abstract Article PDF–275K

Select item 334150118.

New associations of the genetic polymorphisms in nicotinic receptor genes with the risk of lung cancer

Anna Chikova, Hans-Ulrich Bernard, Igor B. Shchepotin, Sergei A. Grando

Life Sci. Author manuscript; available in PMC 2013 Nov 27.

Published in final edited form as: Life Sci. 2012 Nov 27; 91(21-22): 1103–1108. Published online 2012 Jan 17. doi: 10.1016/j.lfs.2011.12.023

PMCID:: PMC3341501

Abstract Article PDF–302K

Select item 326394719.

Specificity Determinants of Allosteric Modulation in the Neuronal Nicotinic Acetylcholine Receptor: a Fine Line between Inhibition and Potentiation

Laura C. Cesa, Colin A. Higgins, Steven R. Sando, Dennis W. Kuo, Mark M. Levandoski

Mol Pharmacol. 2012 Feb; 81(2): 239–249. doi: 10.1124/mol.111.076059

PMCID:: PMC3263947

Abstract Article PDF–958K

Select item 325901620.

Rare missense variants in CHRNB4 are associated with reduced risk of nicotine dependence

Gabe Haller, Todd Druley, Francesco L. Vallania, Robi D. Mitra, Ping Li, Gustav Akk, Joe Henry Steinbach, Naomi Breslau, Eric Johnson, Dorothy Hatsukami, Jerry Stitzel, Laura J. Bierut, Alison M. Goate

Hum Mol Genet. 2012 Feb 1; 21(3): 647–655. Published online 2011 Oct 31. doi: 10.1093/hmg/ddr498