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Select item 112528031.

Wnt/Wingless signaling promotes lipid mobilization through signal-induced transcriptional repression

Mengmeng Liu, Rajitha-Udakara-Sampath Hemba-Waduge, Xiao Li, Xiahe Huang, Tzu-Hao Liu, Xianlin Han, Yingchun Wang, Jun-Yuan Ji

Proc Natl Acad Sci U S A. 2024 Jul 9; 121(28): e2322066121. Published online 2024 Jul 5. doi: 10.1073/pnas.2322066121

PMCID:: PMC11252803

Abstract Article PDF–11M

Select item 111689352.

Senescent glia link mitochondrial dysfunction and lipid accumulation

China N. Byrns, Alexandra E. Perlegos, Karl N. Miller, Zhecheng Jin, Faith R. Carranza, Palak Manchandra, Connor H. Beveridge, Caitlin E. Randolph, V. Sai Chaluvadi, Shirley L. Zhang, Ananth R. Srinivasan, F. C. Bennett, Amita Sehgal, Peter D. Adams, Gaurav Chopra, Nancy M. Bonini

Nature. 2024; 630(8016): 475–483. Published online 2024 Jun 5. doi: 10.1038/s41586-024-07516-8

Correction in:: Nature. 2024; 632(8026): E8.

PMCID:: PMC11168935

Abstract Article PDF–17M

Select item 109681193.

Tricarboxylic Acid Cycle Intermediates and Individual Ageing

Natalia Kurhaluk

Biomolecules. 2024 Mar; 14(3): 260. Published online 2024 Feb 22. doi: 10.3390/biom14030260

PMCID:: PMC10968119

Abstract Article PDF–2.6M

Select item 109650834.

A fatty acid anabolic pathway in specialized-cells sustains a remote signal that controls egg activation in Drosophila

Mickael Poidevin, Nicolas Mazuras, Gwénaëlle Bontonou, Pierre Delamotte, Béatrice Denis, Maëlle Devilliers, Perla Akiki, Delphine Petit, Laura de Luca, Priscilla Soulie, Cynthia Gillet, Claude Wicker-Thomas, Jacques Montagne

PLoS Genet. 2024 Mar; 20(3): e1011186. Published online 2024 Mar 14. doi: 10.1371/journal.pgen.1011186

PMCID:: PMC10965083

Abstract Article PDF–3.7M

Select item 107635465.

Finishing the egg

Celeste Berg, Matthew Sieber, Jianjun Sun

Genetics. 2024 Jan; 226(1): iyad183. Published online 2023 Nov 24. doi: 10.1093/genetics/iyad183

PMCID:: PMC10763546

Abstract Article PDF–1.6M

Select item 107231346.

Late-life shift in caloric intake affects fly metabolism and longevity

Michael Li, Jacob Macro, Kali Meadows, Dushyant Mishra, Dominique Martin, Sara Olson, Billy Joe Huggins, Brenton R. Graveley, James Y. H. Li, Blanka Rogina

Proc Natl Acad Sci U S A. 2023 Dec 12; 120(50): e2311019120. Published online 2023 Dec 8. doi: 10.1073/pnas.2311019120

Correction in:: Proc Natl Acad Sci U S A. 2024 Mar 12; 121(11): e2402651121.

PMCID:: PMC10723134

Abstract Article PDF–2.6M

Select item 106717677.

Yeast Hydrolysate Inhibits Lipid Accumulation via Regulation of Lipid Accumulation-Related Genes in a Drosophila Model of High-Sugar Diet-Induced Obesity

Nari Kim, Yejin Ahn, Kayoung Ko, Boyun Kim, Kisoo Han, Hyung Joo Suh, Jewon Jung, Ki-Bae Hong

Int J Mol Sci. 2023 Nov; 24(22): 16302. Published online 2023 Nov 14. doi: 10.3390/ijms242216302

PMCID:: PMC10671767

Abstract Article PDF–2.7M

Select item 106506358.

Regular Exercise Modulates the dfoxo/dsrebp Pathway to Alleviate High-Fat-Diet-Induced Obesity and Cardiac Dysfunction in Drosophila

Hanhui Yan, Meng Ding, Tianhang Peng, Ping Zhang, Rui Tian, Lan Zheng

Int J Mol Sci. 2023 Nov; 24(21): 15562. Published online 2023 Oct 25. doi: 10.3390/ijms242115562

PMCID:: PMC10650635

Abstract Article PDF–12M

Select item 104951099.

Fat body-specific reduction of CTPS alleviates HFD-induced obesity

Jingnan Liu, Yuanbing Zhang, Qiao-Qi Wang, Youfang Zhou, Ji-Long Liu

eLife. 2023; 12: e85293. Published online 2023 Sep 11. doi: 10.7554/eLife.85293

PMCID:: PMC10495109

Abstract Article PDF–13M

Select item 1010573610.

Next-generation large-scale binary protein interaction network for Drosophila melanogaster

Hong-Wen Tang, Kerstin Spirohn, Yanhui Hu, Tong Hao, István A. Kovács, Yue Gao, Richard Binari, Donghui Yang-Zhou, Kenneth H. Wan, Joel S. Bader, Dawit Balcha, Wenting Bian, Benjamin W. Booth, Atina G. Coté, Steffi de Rouck, Alice Desbuleux, Kah Yong Goh, Dae-Kyum Kim, Jennifer J. Knapp, Wen Xing Lee, Irma Lemmens, Cathleen Li, Mian Li, Roujia Li, Hyobin Julianne Lim, Yifang Liu, Katja Luck, Dylan Markey, Carl Pollis, Sudharshan Rangarajan, Jonathan Rodiger, Sadie Schlabach, Yun Shen, Dayag Sheykhkarimli, Bridget TeeKing, Frederick P. Roth, Jan Tavernier, Michael A. Calderwood, David E. Hill, Susan E. Celniker, Marc Vidal, Norbert Perrimon, Stephanie E. Mohr

Nat Commun. 2023; 14: 2162. Published online 2023 Apr 15. doi: 10.1038/s41467-023-37876-0

PMCID:: PMC10105736

Abstract Article PDF–3.2M

Select item 997493611.

From Worms to Humans: Understanding Intestinal Lipid Metabolism via Model Organisms

Darby W. Kozan, Joshua T. Derrick, William B. Ludington, Steven A. Farber

Biochim Biophys Acta Mol Cell Biol Lipids. Author manuscript; available in PMC 2024 Apr 1.

Published in final edited form as: Biochim Biophys Acta Mol Cell Biol Lipids. 2023 Apr; 1868(4): 159290. Published online 2023 Feb 3. doi: 10.1016/j.bbalip.2023.159290

PMCID:: PMC9974936

Abstract Article PDF–1.5M

Select item 994113512.

SREBP modulates the NADP⁺/NADPH cycle to control night sleep in Drosophila

Vittoria Mariano, Alexandros K. Kanellopoulos, Giuseppe Aiello, Adrian C. Lo, Eric Legius, Tilmann Achsel, Claudia Bagni

Nat Commun. 2023; 14: 763. Published online 2023 Feb 20. doi: 10.1038/s41467-022-35577-8

PMCID:: PMC9941135

Abstract Article PDF–2.9M

Select item 986580813.

Regular Exercise in Drosophila Prevents Age-Related Cardiac Dysfunction Caused by High Fat and Heart-Specific Knockdown of skd

Yurou Cao, Shiyi He, Meng Ding, Wenzhi Gu, Tongquan Wang, Shihu Zhang, Jiadong Feng, Qiufang Li, Lan Zheng

Int J Mol Sci. 2023 Jan; 24(2): 1216. Published online 2023 Jan 7. doi: 10.3390/ijms24021216

PMCID:: PMC9865808

Abstract Article PDF–11M

Select item 970254014.

Cdk8 attenuates lipogenesis by inhibiting SREBP-dependent transcription in Drosophila

Xiao Li, Meng Zhang, Mengmeng Liu, Tzu-Hao Liu, Rajitha-Udakara-Sampath Hemba-Waduge, Jun-Yuan Ji

Dis Model Mech. 2022 Nov 1; 15(11): dmm049650. Published online 2022 Nov 14. doi: 10.1242/dmm.049650

PMCID:: PMC9702540

Abstract Article

Select item 952157115.

Ameliorative effect of bayberry leaves proanthocyanidins on high sugar diet induced Drosophila melanogaster

Mengting Wang, Haiguang Mao, Jianchu Chen, Lili Qi, Jinbo Wang

Front Pharmacol. 2022; 13: 1008580. Published online 2022 Sep 15. doi: 10.3389/fphar.2022.1008580

PMCID:: PMC9521571

Abstract Article PDF–2.5M

Select item 950287816.

Drosophila Keap1 xenobiotic response factor regulates developmental transcription through binding to chromatin

Jennifer Carlson, Lindsey Price, Isabel Cook, Huai Deng

Dev Biol. Author manuscript; available in PMC 2023 Jan 1.

Published in final edited form as: Dev Biol. 2022 Jan; 481: 139–147. Published online 2021 Oct 15. doi: 10.1016/j.ydbio.2021.10.003

PMCID:: PMC9502878

Abstract Article PDF–1021K

Select item 923968017.

An expanded toolkit for Drosophila gene tagging using synthesized homology donor constructs for CRISPR-mediated homologous recombination

Oguz Kanca, Jonathan Zirin, Yanhui Hu, Burak Tepe, Debdeep Dutta, Wen-Wen Lin, Liwen Ma, Ming Ge, Zhongyuan Zuo, Lu-Ping Liu, Robert W Levis, Norbert Perrimon, Hugo J Bellen

eLife. 2022; 11: e76077. Published online 2022 Jun 20. doi: 10.7554/eLife.76077

PMCID:: PMC9239680

Abstract Article PDF–1.2M

Select item 892618918.

Gut-derived peptidoglycan remotely inhibits bacteria dependent activation of SREBP by Drosophila adipocytes

Bernard Charroux, Julien Royet

PLoS Genet. 2022 Mar; 18(3): e1010098. Published online 2022 Mar 4. doi: 10.1371/journal.pgen.1010098

PMCID:: PMC8926189

Abstract Article PDF–3.9M

Select item 885445319.

Recent insights into the role of glia and oxidative stress in Alzheimer’s disease gained from Drosophila.

Lindsey D. Goodman, Hugo J. Bellen

Curr Opin Neurobiol. Author manuscript; available in PMC 2023 Feb 1.

Published in final edited form as: Curr Opin Neurobiol. 2022 Feb; 72: 32–38. Published online 2021 Aug 18. doi: 10.1016/j.conb.2021.07.012

PMCID:: PMC8854453

Abstract Article PDF–571K

Select item 877747820.

Management of altered metabolic activity in Drosophila model of Huntington’s disease by curcumin

Kumari Aditi, Akanksha Singh, Mallikarjun N Shakarad, Namita Agrawal

Exp Biol Med (Maywood) 2022 Jan; 247(2): 152–164. Published online 2021 Nov 7. doi: 10.1177/15353702211046927

PMCID:: PMC8777478

Abstract Article PDF–1.2M

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