U.S. flag

An official website of the United States government

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Links from GEO Profiles

Items: 1 to 20 of 38

1.
EYA2 tyrosine phosphatase inhibition reduces MYC and prevents medulloblastoma progression
Arthur R Wolin, Melanie Y Vincent, Taylor Hotz, Stephen C Purdy, Sheera R Rosenbaum, Connor J Hughes, Jessica Y Hsu, Michael U J Oliphant, Brock Armstrong, Veronica Wessells, Marileila Varella-Garcia, Matthew D Galbraith, Angela Pierce, Dong Wang, Sujatha Venkataraman, Etienne Danis, Bethany Veo, Natalie Serkova, Joaquin M Espinosa, Daniel L Gustafson, Rajeev Vibhakar, Heide L Ford
Neuro Oncol. 2023 Dec; 25(12): 2287–2301. Published online 2023 Jul 24. doi: 10.1093/neuonc/noad128
PMCID:
PMC10708924
AbstractArticlePDF–25M
2.
LncRNA ZNNT1 induces p53 degradation by interfering with the interaction between p53 and the SART3-USP15 complex
Kenzui Taniue, Takeaki Oda, Tomoatsu Hayashi, Yuki Kamoshida, Yasuko Takeda, Anzu Sugawara, Yuki Shimoura, Lumi Negishi, Takeshi Nagashima, Mariko Okada-Hatakeyama, Yoshifumi Kawamura, Naoki Goshima, Nobuyoshi Akimitsu, Tetsu Akiyama
PNAS Nexus. 2023 Jul; 2(7): pgad220. Published online 2023 Jul 4. doi: 10.1093/pnasnexus/pgad220
PMCID:
PMC10337854
AbstractArticlePDF–851K
3.
Structure–activity relationship studies of allosteric inhibitors of EYA2 tyrosine phosphatase
Jothi Anantharajan, Nithya Baburajendran, Grace Lin, Yong Yao Loh, Weijun Xu, Nur Huda Binte Ahmad, Shuang Liu, Anna E. Jansson, John Wee Liang Kuan, Elizabeth Yihui Ng, Yee Khoon Yeo, Alvin W. Hung, Joma Joy, Jeffrey Hill, Heide L. Ford, Rui Zhao, Thomas H. Keller, CongBao Kang
Protein Sci. 2022 Feb; 31(2): 422–431. Published online 2021 Nov 18. doi: 10.1002/pro.4234
PMCID:
PMC8819961
AbstractArticlePDF–2.7M
4.
Targeting EYA2 tyrosine phosphatase activity in glioblastoma stem cells induces mitotic catastrophe
Guoxin Zhang, Zhen Dong, Ryan C. Gimple, Arthur Wolin, Qiulian Wu, Zhixin Qiu, Lisa M. Wood, Jia Z. Shen, Li Jiang, Linjie Zhao, Deguan Lv, Briana C. Prager, Leo J.Y. Kim, Xiuxing Wang, Lingdi Zhang, Ryan L. Anderson, Jeffrey K. Moore, Shideng Bao, Thomas H. Keller, Grace Lin, Congbao Kang, Petra Hamerlik, Rui Zhao, Heide L. Ford, Jeremy N. Rich
J Exp Med. 2021 Nov 1; 218(11): e20202669. Published online 2021 Oct 7. doi: 10.1084/jem.20202669
PMCID:
PMC8504185
AbstractArticlePDF–12M
5.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
6.
EYA2 suppresses the progression of hepatocellular carcinoma via SOCS3-mediated blockade of JAK/STAT signaling
Ze-Kun Liu, Can Li, Ren-Yu Zhang, Ding Wei, Yu-Kui Shang, Yu-Le Yong, Ling-Min Kong, Nai-Shan Zheng, Ke Liu, Meng Lu, Man Liu, Cai-Xia Hu, Xiao-Zhen Yang, Zhi-Nan Chen, Huijie Bian
Mol Cancer. 2021; 20: 79. Published online 2021 May 27. doi: 10.1186/s12943-021-01377-9
PMCID:
PMC8157759
AbstractArticlePDF–4.8M
7.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
8.
Eya2 Is Overexpressed in Human Prostate Cancer and Regulates Docetaxel Sensitivity and Mitochondrial Membrane Potential through AKT/Bcl-2 Signaling
Zhongyuan Liu, Long Zhao, Yongsheng Song
Biomed Res Int. 2019; 2019: 3808432. Published online 2019 Jun 16. doi: 10.1155/2019/3808432
PMCID:
PMC6601494
AbstractArticlePDF–2.4M
9.
A Global Analysis of The Receptor Tyrosine Kinase – Protein Phosphatase Interactome
Zhong Yao, Katelyn Darowski, Nicole St-Denis, Victoria Wong, Fabian Offensperger, Annabel Villedieu, Shahreen Amin, Ramy Malty, Hiroyuki Aoki, Hongbo Guo, Yang Xu, Caterina Iorio, Max Kotlyar, Andrew Emili, Igor Jurisica, Benjamin G Neel, Mohan Babu, Anne-Claude Gingras, Igor Stagljar
Mol Cell. Author manuscript; available in PMC 2017 Oct 31.
Published in final edited form as: Mol Cell. 2017 Jan 19; 65(2): 347–360. Published online 2017 Jan 5. doi: 10.1016/j.molcel.2016.12.004
PMCID:
PMC5663465
AbstractArticlePDF–2.1M
10.
Eya2 overexpression promotes the invasion of human astrocytoma through the regulation of ERK/MMP9 signaling
Zhifeng Wen, Chuansheng Liang, Qichen Pan, Yunjie Wang
Int J Mol Med. 2017 Nov; 40(5): 1315–1322. Published online 2017 Sep 13. doi: 10.3892/ijmm.2017.3132
PMCID:
PMC5627874
AbstractArticlePDF–1020K
11.
The EGFR/miR-338-3p/EYA2 axis controls breast tumor growth and lung metastasis
Yingchun Liang, Xiaojie Xu, Tao Wang, Ying Li, Wenye You, Jing Fu, Yang Liu, Shuai Jin, Quanbo Ji, Wei Zhao, Qi Song, Ling Li, Tian Hong, Junjian Huang, Zhaohui Lyu, Qinong Ye
Cell Death Dis. 2017 Jul; 8(7): e2928. Published online 2017 Jul 13. doi: 10.1038/cddis.2017.325
PMCID:
PMC5550870
AbstractArticlePDF–4.4M
12.
A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling
Parveen Kumar, Prathyusha Munnangi, KVS Rammohan Chowdary, Varun J. Shah, Swapnil R. Shinde, Nanci R. Kolli, Rachita R. Halehalli, Hampapathalu A. Nagarajaram, Subbareddy Maddika
J Proteome Res. 2017 Aug 4; 16(8): 2789–2801. Published online 2017 Jul 4. doi: 10.1021/acs.jproteome.7b00065
PMCID:
PMC5548413
AbstractArticlePDF–5.2M
13.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
14.
Eya2, a Target Activated by Plzf, Is Critical for PLZF-RARA-Induced Leukemogenesis
Ryoichi Ono, Masahiro Masuya, Satomi Ishii, Naoyuki Katayama, Tetsuya Nosaka
Mol Cell Biol. 2017 Jul 1; 37(13): e00585-16. Prepublished online 2017 Apr 17. Published online 2017 Jun 15. doi: 10.1128/MCB.00585-16
PMCID:
PMC5472835
AbstractArticlePDF–5.9M
15.
Defining the Protein-Protein Interaction Network of the Human Protein Tyrosine Phosphatase Family
Xu Li, Kim My Tran, Kathryn E. Aziz, Alexey V. Sorokin, Junjie Chen, Wenqi Wang
Mol Cell Proteomics. 2016 Sep; 15(9): 3030–3044. Published online 2016 Jul 18. doi: 10.1074/mcp.M116.060277
PMCID:
PMC5013315
AbstractArticlePDF–3.2M
16.
Overexpression of miR-30a in lung adenocarcinoma A549 cell line inhibits migration and invasion via targeting EYA2
Yuncang Yuan, Shangyong Zheng, Qian Li, Xudong Xiang, Tangxin Gao, Pengzhan Ran, Lijuan Sun, Qionglin Huang, Fei Xie, Jing Du, Chunjie Xiao
Acta Biochim Biophys Sin (Shanghai) 2016 Mar; 48(3): 220–228. Published online 2016 Feb 1. doi: 10.1093/abbs/gmv139
PMCID:
PMC4885132
AbstractArticlePDF–828K
17.
The SIX1-EYA transcriptional complex as a therapeutic target in cancer
Melanie A Blevins, Christina Garlington Towers, Aaron N. Patrick, Rui Zhao, Heide L. Ford
Expert Opin Ther Targets. Author manuscript; available in PMC 2016 Feb 1.
Published in final edited form as: Expert Opin Ther Targets. 2015 Feb; 19(2): 213–225. Published online 2015 Jan 2. doi: 10.1517/14728222.2014.978860
PMCID:
PMC4336540
AbstractArticlePDF–543K
18.
Epigenetic silencing of EYA2 in pancreatic adenocarcinomas promotes tumor growth
Audrey Vincent, Seung-Mo Hong, Chaoxin Hu, Noriyuki Omura, Angela Young, Haeryoung Kim, Jun Yu, Spencer Knight, Michael Ayars, Margaret Griffith, Isabelle Van Seuningen, Anirban Maitra, Michael Goggins
Oncotarget. 2014 May; 5(9): 2575–2587. Published online 2014 Mar 22. doi: 10.18632/oncotarget.1842
PMCID:
PMC4058028
AbstractArticlePDF–4.6M
19.
Crystal structure of ED-Eya2: insight into dual roles as a protein tyrosine phosphatase and a transcription factor
Suk-Kyeong Jung, Dae Gwin Jeong, Sang J. Chung, Jae Hoon Kim, Byoung Chul Park, Nicholas K. Tonks, Seong Eon Ryu, Seung Jun Kim
FASEB J. 2010 Feb; 24(2): 560–569. doi: 10.1096/fj.09-143891
PMCID:
PMC4048942
AbstractArticle
20.
CDK6 binds and promotes the degradation of the EYA2 protein
Dawn Kohrt, Jennifer Crary, Marc Zimmer, Aaron N Patrick, Heide L Ford, Philip W Hinds, Martha J Grossel
Cell Cycle. 2014 Jan 1; 13(1): 62–71. Published online 2013 Oct 12. doi: 10.4161/cc.26755
PMCID:
PMC3925736
AbstractArticlePDF–1.2M

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Filter your results:

Find related data

Recent activity

Clear Turn Off Turn On

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
You are here: NCBI > Literature > PubMed Central (PMC)
Support Center