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Items: 1 to 20 of 98

1.
Antagonistic roles of canonical and alternative-RPA in disease-associated tandem CAG repeat instability
Terence Gall-Duncan, Jennifer Luo, Carla-Marie Jurkovic, Laura A. Fischer, Kyota Fujita, Amit L. Deshmukh, Rachel J. Harding, Stephanie Tran, Mustafa Mehkary, Vanessa Li, David E. Leib, Ran Chen, Hikari Tanaka, Amanda G. Mason, Dominique Lévesque, Mahreen Khan, Mortezaali Razzaghi, Tanya Prasolava, Stella Lanni, Nozomu Sato, Marie-Christine Caron, Gagan B. Panigrahi, Peixiang Wang, Rachel Lau, Arturo López Castel, Jean-Yves Masson, Lynette Tippett, Clinton Turner, Maria Spies, Albert R. La Spada, Eric I. Campos, Maurice A. Curtis, François-Michel Boisvert, Richard L.M. Faull, Beverly L. Davidson, Masayuki Nakamori, Hitoshi Okazawa, Marc S. Wold, Christopher E. Pearson
Cell. Author manuscript; available in PMC 2024 Oct 26.
Published in final edited form as: Cell. 2023 Oct 26; 186(22): 4898–4919.e25. Published online 2023 Oct 11. doi: 10.1016/j.cell.2023.09.008
PMCID:
PMC11209935
AbstractArticlePDF–3.0M
2.
HBO1 determines SMAD action in pluripotency and mesendoderm specification
Cong Zhang, Yongli Shan, Huaisong Lin, Yanqi Zhang, Qi Xing, Jinmin Zhu, Tiancheng Zhou, Aiping Lin, Qianyu Chen, Junwei Wang, Guangjin Pan
Nucleic Acids Res. 2024 May 22; 52(9): 4935–4949. Published online 2024 Feb 29. doi: 10.1093/nar/gkae158
PMCID:
PMC11109972
AbstractArticlePDF–4.1M
3.
Deciphering structure, function and mechanism of lysine acetyltransferase HBO1 in protein acetylation, transcription regulation, DNA replication and its oncogenic properties in cancer
Rongfeng Lan, Qianqian Wang
Cell Mol Life Sci. 2020 Feb; 77(4): 637–649. Published online 2019 Sep 18. doi: 10.1007/s00018-019-03296-x
PMCID:
PMC11104888
AbstractArticlePDF–3.8M
4.
Histone acetylation by HBO1 (KAT7) activates Wnt/β-catenin signaling to promote leukemogenesis in B-cell acute lymphoblastic leukemia
Hao Wang, Yingqi Qiu, Honghao Zhang, Ning Chang, Yuxing Hu, Jianyu Chen, Rong Hu, Peiyun Liao, Zhongwei Li, Yulu Yang, Qingyan Cen, Xiangyang Ding, Meifang Li, Xiaoling Xie, Yuhua Li
Cell Death Dis. 2023 Aug; 14(8): 498. Published online 2023 Aug 4. doi: 10.1038/s41419-023-06019-0
PMCID:
PMC10403501
AbstractArticlePDF–6.1M
5.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M
6.
Cross-linking mass spectrometry discovers, evaluates, and corroborates structures and protein–protein interactions in the human cell
Tara K. Bartolec, Xabier Vázquez-Campos, Alexander Norman, Clement Luong, Marcus Johnson, Richard J. Payne, Marc R. Wilkins, Joel P. Mackay, Jason K. K. Low
Proc Natl Acad Sci U S A. 2023 Apr 25; 120(17): e2219418120. Published online 2023 Apr 18. doi: 10.1073/pnas.2219418120
PMCID:
PMC10151615
AbstractArticlePDF–2.9M
7.
Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity
Martin Golkowski, Andrea Lius, Tanmay Sapre, Ho-Tak Lau, Taylor Moreno, Dustin J. Maly, Shao-En Ong
Mol Cell. Author manuscript; available in PMC 2023 Apr 4.
Published in final edited form as: Mol Cell. 2023 Mar 2; 83(5): 803–818.e8. Published online 2023 Feb 2. doi: 10.1016/j.molcel.2023.01.015
PMCID:
PMC10072906
AbstractArticlePDF–4.2M
8.
KAT7 promotes radioresistance through upregulating PI3K/AKT signaling in breast cancer
Yan Ma, Xiaohua Chen, Ting Ding, Hanqun Zhang, Qiuning Zhang, Huanyu Dai, Haibo Zhang, Jianming Tang, Xiaohu Wang
J Radiat Res. 2023 Mar; 64(2): 448–456. Published online 2023 Feb 1. doi: 10.1093/jrr/rrac107
Correction in:
J Radiat Res. 2023 May; 64(3): 632.
PMCID:
PMC10036104
AbstractArticlePDF–1.0M
9.
KAT7-mediated CANX (calnexin) crotonylation regulates leucine-stimulated MTORC1 activity
Guokai Yan, Xiuzhi Li, Zilong Zheng, Weihua Gao, Changqing Chen, Xinkai Wang, Zhongyi Cheng, Jie Yu, Geng Zou, Muhammad Zahid Farooq, Xiaoyan Zhu, Weiyun Zhu, Qing Zhong, Xianghua Yan
Autophagy. 2022; 18(12): 2799–2816. Published online 2022 Mar 10. doi: 10.1080/15548627.2022.2047481
PMCID:
PMC9673962
AbstractArticlePDF–19M
10.
The in vivo Interaction Landscape of Histones H3.1 and H3.3
Robert Siddaway, Scott Milos, Étienne Coyaud, Hwa Young Yun, Shahir M. Morcos, Sanja Pajovic, Eric I. Campos, Brian Raught, Cynthia Hawkins
Mol Cell Proteomics. 2022 Oct; 21(10): 100411. Published online 2022 Sep 9. doi: 10.1016/j.mcpro.2022.100411
PMCID:
PMC9540345
AbstractArticlePDF–3.9M
11.
Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer
Annamaria Salvati, Viola Melone, Assunta Sellitto, Francesca Rizzo, Roberta Tarallo, Tuula A. Nyman, Giorgio Giurato, Giovanni Nassa, Alessandro Weisz
Breast Cancer Res. 2022; 24: 52. Published online 2022 Jul 18. doi: 10.1186/s13058-022-01547-7
PMCID:
PMC9290241
AbstractArticlePDF–8.2M
12.
HBO1 induces histone acetylation and is important for non-small cell lung cancer cell growth
Teng-fei Chen, Hui-fei Hao, Yan Zhang, Xiao-yu Chen, Hua-si Zhao, Rui Yang, Ping Li, Ling-xiao Qiu, Yong-hua Sang, Chun Xu, Shao-xia Liu
Int J Biol Sci. 2022; 18(8): 3313–3323. Published online 2022 May 9. doi: 10.7150/ijbs.72526
PMCID:
PMC9134900
AbstractArticlePDF–2.7M
13.
OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization
Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti
Science. Author manuscript; available in PMC 2022 Sep 11.
Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983
PMCID:
PMC9119736
AbstractArticlePDF–3.3M
14.
Transcription Factor Protein Interactomes Reveal Genetic Determinants in Heart Disease
Barbara Gonzalez-Teran, Maureen Pittman, Franco Felix, Reuben Thomas, Desmond Richmond-Buccola, Ruth Hüttenhain, Krishna Choudhary, Elisabetta Moroni, Mauro W. Costa, Yu Huang, Arun Padmanabhan, Michael Alexanian, Clara Youngna Lee, Bonnie E. J. Maven, Kaitlen Samse-Knapp, Sarah U. Morton, Michael McGregor, Casey A. Gifford, J. G. Seidman, Christine E. Seidman, Bruce D. Gelb, Giorgio Colombo, Bruce R. Conklin, Brian L. Black, Benoit G. Bruneau, Nevan J. Krogan, Katherine S. Pollard, Deepak Srivastava
Cell. Author manuscript; available in PMC 2023 Mar 3.
Published in final edited form as: Cell. 2022 Mar 3; 185(5): 794–814.e30. Published online 2022 Feb 18. doi: 10.1016/j.cell.2022.01.021
PMCID:
PMC8923057
AbstractArticlePDF–2.5M
15.
HBO1 is a versatile histone acyltransferase critical for promoter histone acylations
Yanhui Xiao, Wenjing Li, Hui Yang, Lulu Pan, Liwei Zhang, Lu Lu, Jiwei Chen, Wei Wei, Jie Ye, Jiwen Li, Guohong Li, Yong Zhang, Minjia Tan, Jianping Ding, Jiemin Wong
Nucleic Acids Res. 2021 Aug 20; 49(14): 8037–8059. Published online 2021 Jul 14. doi: 10.1093/nar/gkab607
PMCID:
PMC8661427
AbstractArticlePDF–8.0M
16.
HBO1-MLL interaction promotes AF4/ENL/P-TEFb-mediated leukemogenesis
Satoshi Takahashi, Akinori Kanai, Hiroshi Okuda, Ryo Miyamoto, Yosuke Komata, Takeshi Kawamura, Hirotaka Matsui, Toshiya Inaba, Akifumi Takaori-Kondo, Akihiko Yokoyama
eLife. 2021; 10: e65872. Published online 2021 Aug 25. doi: 10.7554/eLife.65872
PMCID:
PMC8387021
AbstractArticlePDF–2.4M
17.
Integrative oncogene-dependency mapping identifies RIT1 vulnerabilities and synergies in lung cancer
Athea Vichas, Amanda K. Riley, Naomi T. Nkinsi, Shriya Kamlapurkar, Phoebe C. R. Parrish, April Lo, Fujiko Duke, Jennifer Chen, Iris Fung, Jacqueline Watson, Matthew Rees, Austin M. Gabel, James D. Thomas, Robert K. Bradley, John K. Lee, Emily M. Hatch, Marina K. Baine, Natasha Rekhtman, Marc Ladanyi, Federica Piccioni, Alice H. Berger
Nat Commun. 2021; 12: 4789. Published online 2021 Aug 9. doi: 10.1038/s41467-021-24841-y
PMCID:
PMC8352964
AbstractArticlePDF–4.5M
18.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
19.
The histone acetyltransferase HBO1 functions as a novel oncogenic gene in osteosarcoma
Yan-yang Gao, Zhuo-yan Ling, Yun-Rong Zhu, Ce Shi, Yin Wang, Xiang-yang Zhang, Zhi-qing Zhang, Qin Jiang, Min-Bin Chen, Shuofei Yang, Cong Cao
Theranostics. 2021; 11(10): 4599–4615. Published online 2021 Mar 4. doi: 10.7150/thno.55655
PMCID:
PMC7978299
AbstractArticlePDF–4.2M
20.
FBW7 suppresses ovarian cancer development by targeting the N6-methyladenosine binding protein YTHDF2
Fei Xu, Jiajia Li, Mengdong Ni, Jingyi Cheng, Haiyun Zhao, Shanshan Wang, Xiang Zhou, Xiaohua Wu
Mol Cancer. 2021; 20: 45. Published online 2021 Mar 3. doi: 10.1186/s12943-021-01340-8
PMCID:
PMC7927415
AbstractArticlePDF–2.9M

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