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Items: 1 to 20 of 31

1.
The positive feedback loop of the NAT10/Mybbp1a/p53 axis promotes cardiomyocyte ferroptosis to exacerbate cardiac I/R injury
Zhezhe Qu, Xiaochen Pang, Zhongting Mei, Ying Li, Yaozhi Zhang, Chuanhao Huang, Kuiwu Liu, Shuting Yu, Changhao Wang, Zhiyong Sun, Yingqi Liu, Xin Li, Yingqiong Jia, Yuechao Dong, Meixi Lu, Tiantian Ju, Fan Wu, Min Huang, Na Li, Shunkang Dou, Jianhao Jiang, Xianhui Dong, Yi Zhang, Wanhong Li, Baofeng Yang, Weijie Du
Redox Biol. 2024 Jun; 72: 103145. Published online 2024 Apr 2. doi: 10.1016/j.redox.2024.103145
PMCID:
PMC11002668
AbstractArticlePDF–11M
2.
NAT10‐mediated ac4C‐modified ANKZF1 promotes tumor progression and lymphangiogenesis in clear‐cell renal cell carcinoma by attenuating YWHAE‐driven cytoplasmic retention of YAP1
Daojia Miao, Jian Shi, Qingyang Lv, Diaoyi Tan, Chuanyi Zhao, Zhiyong Xiong, Xiaoping Zhang
Cancer Commun (Lond) 2024 Mar; 44(3): 361–383. Published online 2024 Feb 26. doi: 10.1002/cac2.12523
PMCID:
PMC10962679
AbstractArticlePDF–21M
3.
N-Acetyltransferase 10 represses Uqcr11 and Uqcrb independently of ac4C modification to promote heart regeneration
Wenya Ma, Yanan Tian, Leping Shi, Jing Liang, Qimeng Ouyang, Jianglong Li, Hongyang Chen, Hongyue Sun, Haoyu Ji, Xu Liu, Wei Huang, Xinlu Gao, Xiaoyan Jin, Xiuxiu Wang, Yining Liu, Yang Yu, Xiaofei Guo, Ye Tian, Fan Yang, Faqian Li, Ning Wang, Benzhi Cai
Nat Commun. 2024; 15: 2137. Published online 2024 Mar 8. doi: 10.1038/s41467-024-46458-7
PMCID:
PMC10923914
AbstractArticlePDF–20M
4.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
5.
Maternal NAT10 orchestrates oocyte meiotic cell-cycle progression and maturation in mice
Xue Jiang, Yu Cheng, Yuzhang Zhu, Caoling Xu, Qiaodan Li, Xuemei Xing, Wenqing Li, Jiaqi Zou, Lan Meng, Muhammad Azhar, Yuzhu Cao, Xianhong Tong, Weibing Qin, Xiaoli Zhu, Jianqiang Bao
Nat Commun. 2023; 14: 3729. Published online 2023 Jun 22. doi: 10.1038/s41467-023-39256-0
PMCID:
PMC10287700
AbstractArticlePDF–13M
6.
The Cytidine N-Acetyltransferase NAT10 Participates in Peripheral Nerve Injury-Induced Neuropathic Pain by Stabilizing SYT9 Expression in Primary Sensory Neurons
Ming Zhang, Kehui Yang, Qi-Hui Wang, Ling Xie, Qiaoqiao Liu, Runa Wei, Yang Tao, Hong-Li Zheng, Ninghua Lin, Hengjun Xu, Li Yang, Hongjun Wang, Tingruo Zhang, Zhouya Xue, Jun-Li Cao, Zhiqiang Pan
J Neurosci. 2023 Apr 26; 43(17): 3009–3027. doi: 10.1523/JNEUROSCI.2321-22.2023
PMCID:
PMC10146489
AbstractArticlePDF–6.0M
7.
NAT10-mediated N4-acetylcytidine modification is required for meiosis entry and progression in male germ cells
Lu Chen, Wen-Jing Wang, Qiang Liu, Yu-Ke Wu, Yun-Wen Wu, Yu Jiang, Xiu-Quan Liao, Fei Huang, Yang Li, Li Shen, Chao Yu, Song-Ying Zhang, Li-Ying Yan, Jie Qiao, Qian-Qian Sha, Heng-Yu Fan
Nucleic Acids Res. 2022 Oct 28; 50(19): 10896–10913. Published online 2022 Jul 8. doi: 10.1093/nar/gkac594
PMCID:
PMC9638909
AbstractArticlePDF–15M
8.
NAT10 regulates neutrophil pyroptosis in sepsis via acetylating ULK1 RNA and activating STING pathway
Hao Zhang, Zhaoyuan Chen, Ji’an Zhou, Jiahui Gu, Han Wu, Yi Jiang, Shenjia Gao, Yun Liao, Ruling Shen, Changhong Miao, Wankun Chen
Commun Biol. 2022; 5: 916. Published online 2022 Sep 6. doi: 10.1038/s42003-022-03868-x
Correction in:
Commun Biol. 2022; 5: 1091.
PMCID:
PMC9448771
AbstractArticlePDF–3.8M
9.
NAT10‐mediated mRNA N4‐acetylcytidine modification promotes bladder cancer progression
Ganping Wang, Ming Zhang, Yiming Zhang, Yanqi Xie, Jiepeng Zou, Jianye Zhong, Zhijia Zheng, Xianghui Zhou, Yuhang Zheng, Binshen Chen, Chunxiao Liu
Clin Transl Med. 2022 May; 12(5): e738. Published online 2022 May 6. doi: 10.1002/ctm2.738
PMCID:
PMC9076013
AbstractArticlePDF–11M
10.
Functional genomic landscape of cancer-intrinsic evasion of killing by T cells
Keith A. Lawson, Cristovão M. Sousa, Xiaoyu Zhang, Eiru Kim, Rummy Akthar, Joseph J. Caumanns, Yuxi Yao, Nicholas Mikolajewicz, Catherine Ross, Kevin R. Brown, Abdelrahman Abou Zid, Zi Peng Fan, Shirley Hui, Jordan A. Krall, Donald M. Simons, Chloe J. Slater, Victor De Jesus, Lujia Tang, Richa Singh, Joshua E. Goldford, Sarah Martin, Qian Huang, Elizabeth A. Francis, Andrea Habsid, Ryan Climie, David Tieu, Jiarun Wei, Ren Li, Amy Hin Yan Tong, Michael Aregger, Katherine S. Chan, Hong Han, Xiaowei Wang, Patricia Mero, John H. Brumell, Antonio Finelli, Laurie Ailles, Gary Bader, Gromoslaw A. Smolen, Gillian A. Kingsbury, Traver Hart, Charles Kung, Jason Moffat
Nature. Author manuscript; available in PMC 2022 Apr 18.
Published in final edited form as: Nature. 2020 Oct; 586(7827): 120–126. Published online 2020 Sep 23. doi: 10.1038/s41586-020-2746-2
PMCID:
PMC9014559
AbstractArticlePDF–6.6M
11.
RNA‐Binding Protein IGF2BP2/IMP2 is a Critical Maternal Activator in Early Zygotic Genome Activation
Hong‐Bin Liu, Tahir Muhammad, Yueshuai Guo, Meng‐Jing Li, Qian‐Qian Sha, Chuan‐Xin Zhang, Hui Liu, Shi‐Gang Zhao, Han Zhao, Hao Zhang, Yan‐Zhi Du, Kang Sun, Kui Liu, Gang Lu, Xue‐Jiang Guo, Jiahao Sha, Heng‐Yu Fan, Fei Gao, Zi‐Jiang Chen
Adv Sci (Weinh) 2019 Aug 7; 6(15): 1900295. Published online 2019 May 24. doi: 10.1002/advs.201900295
PMCID:
PMC6685478
AbstractArticlePDF–3.0M
12.
Mouse screen reveals multiple new genes underlying mouse and human hearing loss
Neil J. Ingham, Selina A. Pearson, Valerie E. Vancollie, Victoria Rook, Morag A. Lewis, Jing Chen, Annalisa Buniello, Elisa Martelletti, Lorenzo Preite, Chi Chung Lam, Felix D. Weiss, Zӧe Powis, Pim Suwannarat, Christopher J. Lelliott, Sally J. Dawson, Jacqueline K. White, Karen P. Steel
PLoS Biol. 2019 Apr; 17(4): e3000194. Published online 2019 Apr 11. doi: 10.1371/journal.pbio.3000194
PMCID:
PMC6459510
AbstractArticlePDF–5.1M
13.
Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells
Sunyuan Zhang, Nicholas A. Williamson, Marie A. Bogoyevitch
Sci Data. 2018; 5: 180262. Published online 2018 Nov 20. doi: 10.1038/sdata.2018.262
PMCID:
PMC6244183
AbstractArticlePDF–753K
14.
Targeting of NAT10 enhances healthspan in a mouse model of human accelerated aging syndrome
Gabriel Balmus, Delphine Larrieu, Ana C. Barros, Casey Collins, Monica Abrudan, Mukerrem Demir, Nicola J. Geisler, Christopher J. Lelliott, Jacqueline K. White, Natasha A. Karp, James Atkinson, Andrea Kirton, Matt Jacobsen, Dean Clift, Raphael Rodriguez, Sanger Mouse Genetics Project, David J. Adams, Stephen P. Jackson
Nat Commun. 2018; 9: 1700. Published online 2018 Apr 27. doi: 10.1038/s41467-018-03770-3
PMCID:
PMC5923383
AbstractArticlePDF–2.1M
15.
Spatio-temporal profile of postynaptic interactomes integrates components of complex brain disorders
Jing Li, Wangshu Zhang, Hui Yang, Daniel P. Howrigan, Brent Wilkinson, Tade Souaiaia, Oleg V. Evgrafov, Giulio Genovese, Veronica A. Clementel, Jennifer C. Tudor, Ted Abel, James A. Knowles, Benjamin M. Neale, Kai Wang, Fengzhu Sun, Marcelo P. Coba
Nat Neurosci. Author manuscript; available in PMC 2018 Aug 1.
Published in final edited form as: Nat Neurosci. 2017 Aug; 20(8): 1150–1161. Published online 2017 Jun 26. doi: 10.1038/nn.4594
PMCID:
PMC5645082
AbstractArticlePDF–2.3M
16.
Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function
Tingting Zhang, Wei Du, Andrew F. Wilson, Satoshi H. Namekawa, Paul R. Andreassen, Amom Ruhikanta Meetei, Qishen Pang
Sci Rep. 2017; 7: 45626. Published online 2017 Apr 5. doi: 10.1038/srep45626
PMCID:
PMC5381226
AbstractArticlePDF–1.4M
17.
The E3 Ubiquitin Ligases, HUWE1 and NEDD4-1, Are Involved in the Post-translational Regulation of the ABCG1 and ABCG4 Lipid Transporters
Shereen M. Aleidi, Vicky Howe, Laura J. Sharpe, Alryel Yang, Geetha Rao, Andrew J. Brown, Ingrid C. Gelissen
J Biol Chem. 2015 Oct 2; 290(40): 24604–24613. Published online 2015 Aug 20. doi: 10.1074/jbc.M115.675579
PMCID:
PMC4591838
AbstractArticlePDF–1.2M
18.
Pharmacological targeting of the Wdr5-MLL interaction in C/EBPa N-terminal leukemia
Florian Grebien, Masoud Vedadi, Matthäus Getlik, Roberto Giambruno, Amit Grover, Roberto Avellino, Anna Skucha, Sarah Vittori, Ekaterina Kuznetsova, David Smil, Dalia Barsyte-Lovejoy, Fengling Li, Gennadiy Poda, Matthieu Schapira, Hong Wu, Aiping Dong, Guillermo Senisterra, Alexey Stukalov, Kilian V. M. Huber, Andreas Schönegger, Richard Marcellus, Martin Bilban, Christoph Bock, Peter J. Brown, Johannes Zuber, Keiryn L. Bennett, Rima Al-awar, Ruud Delwel, Claus Nerlov, Cheryl H. Arrowsmith, Giulio Superti-Furga
Nat Chem Biol. Author manuscript; available in PMC 2016 Feb 1.
Published in final edited form as: Nat Chem Biol. 2015 Aug; 11(8): 571–578. Published online 2015 Jul 13. doi: 10.1038/nchembio.1859
PMCID:
PMC4511833
AbstractArticlePDF–2.2M
19.
The Central Role of EED in the Orchestration of Polycomb Group Complexes
Qi Cao, Xiaoju Wang, Meng Zhao, Rendong Yang, Rohit Malik, Yuanyuan Qiao, Anton Poliakov, Anastasia K. Yocum, Yong Li, Wei Chen, Xuhong Cao, Xia Jiang, Arun Dahiya, Clair Harris, Felix Y. Feng, Sundeep Kalantry, Zhaohui S. Qin, Saravana M. Dhanasekaran, Arul M. Chinnaiyan
Nat Commun. Author manuscript; available in PMC 2014 Jul 24.
Published in final edited form as: Nat Commun. 2014; 5: 3127. doi: 10.1038/ncomms4127
PMCID:
PMC4073494
AbstractArticlePDF–2.1M
20.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M

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