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Select item 97469161.

HIF1 inhibitor acriflavine rescues early-onset preeclampsia phenotype in mice lacking placental prolyl hydroxylase domain protein 2

Julien Sallais, Chanho Park, Sruthi Alahari, Tyler Porter, Ruizhe Liu, Merve Kurt, Abby Farrell, Martin Post, Isabella Caniggia

JCI Insight. 2022 Dec 8; 7(23): e158908. Published online 2022 Dec 8. doi: 10.1172/jci.insight.158908

PMCID:: PMC9746916

Abstract Article PDF–7.1M

Select item 96211422.

CD69 expression on regulatory T cells protects from immune damage after myocardial infarction

Rafael Blanco-Domínguez, Hortensia de la Fuente, Cristina Rodríguez, Laura Martín-Aguado, Raquel Sánchez-Díaz, Rosa Jiménez-Alejandre, Iker Rodríguez-Arabaolaza, Andrea Curtabbi, Marcos M. García-Guimaraes, Alberto Vera, Fernando Rivero, Javier Cuesta, Luis J. Jiménez-Borreguero, Alberto Cecconi, Albert Duran-Cambra, Manel Taurón, Judith Alonso, Héctor Bueno, María Villalba-Orero, Jose Antonio Enríquez, Simon C. Robson, Fernando Alfonso, Francisco Sánchez-Madrid, José Martínez-González, Pilar Martín

J Clin Invest. 2022 Nov 1; 132(21): e152418. Published online 2022 Nov 1. doi: 10.1172/JCI152418

PMCID:: PMC9621142

Abstract Article PDF–3.7M

Select item 66057483.

Sphingosine-1-phosphate receptor 2 restrains egress of γδ T cells from the skin

Brian J. Laidlaw, Elizabeth E. Gray, Yang Zhang, Francisco Ramírez-Valle, Jason G. Cyster

J Exp Med. 2019 Jul 1; 216(7): 1487–1496. Published online 2019 Jun 3. doi: 10.1084/jem.20190114

PMCID:: PMC6605748

Abstract Article PDF–1.9M

Select item 61387394.

CD69 prevents PLZF^hi innate precursors from prematurely exiting the thymus and aborting NKT2 cell differentiation

Motoko Y. Kimura, Akemi Igi, Koji Hayashizaki, Yukiyoshi Mita, Miho Shinzawa, Tejas Kadakia, Yukihiro Endo, Satomi Ogawa, Ryoji Yagi, Shinichiro Motohashi, Alfred Singer, Toshinori Nakayama

Nat Commun. 2018; 9: 3749. Published online 2018 Sep 14. doi: 10.1038/s41467-018-06283-1

PMCID:: PMC6138739

Abstract Article PDF–2.5M

Select item 61255845.

CD69 enhances immunosuppressive function of regulatory T-cells and attenuates colitis by prompting IL-10 production

Lei Yu, Fei Yang, Fanghui Zhang, Danfeng Guo, Ling Li, Xian Wang, Tingbo Liang, Jianli Wang, Zhijian Cai, Hongchuan Jin

Cell Death Dis. 2018 Sep; 9(9): 905. Published online 2018 Sep 5. doi: 10.1038/s41419-018-0927-9

PMCID:: PMC6125584

Abstract Article PDF–2.6M

Select item 56750206.

Lymph node S1P gradients position natural killer cells and regulate their interferon-γ response

Victoria Fang, V. Sai Chaluvadi, Willy D. Ramos-Perez, Alejandra Mendoza, Audrey Baeyens, Richard Rivera, Jerold Chun, Michael Cammer, Susan R. Schwab

Nat Immunol. Author manuscript; available in PMC 2017 Nov 7.

Published in final edited form as: Nat Immunol. 2017 Jan; 18(1): 15–25. Published online 2016 Nov 14. doi: 10.1038/ni.3619

PMCID:: PMC5675020

Abstract Article PDF–1.5M

Select item 54768047.

VCAM1 acts in parallel with CD69 and is required for the initiation of oligodendrocyte myelination

Yuki Miyamoto, Tomohiro Torii, Akito Tanoue, Junji Yamauchi

Nat Commun. 2016; 7: 13478. Published online 2016 Nov 23. doi: 10.1038/ncomms13478

PMCID:: PMC5476804

Abstract Article PDF–9.1M

Select item 53942768.

Thymus-Derived Regulatory T Cell Development Is Regulated by C-Type Lectin-Mediated BIC/MicroRNA 155 Expression

Raquel Sánchez-Díaz, Rafael Blanco-Dominguez, Sandra Lasarte, Katerina Tsilingiri, Enrique Martín-Gayo, Beatriz Linillos-Pradillo, Hortensia de la Fuente, Francisco Sánchez-Madrid, Rinako Nakagawa, María L. Toribio, Pilar Martín

Mol Cell Biol. 2017 May 1; 37(9): e00341-16. Prepublished online 2017 Feb 6. Published online 2017 Apr 14. doi: 10.1128/MCB.00341-16

PMCID:: PMC5394276

Abstract Article PDF–3.4M

Select item 51597069.

DR3 signaling modulates the function of Foxp3⁺ regulatory T cells and the severity of acute graft-versus-host disease

Hidekazu Nishikii, Byung-Su Kim, Yasuhisa Yokoyama, Yan Chen, Jeanette Baker, Antonio Pierini, Maite Alvarez, Melissa Mavers, Kristina Maas-Bauer, Yuqiong Pan, Shigeru Chiba, Robert S. Negrin

Blood. 2016 Dec 15; 128(24): 2846–2858. Prepublished online 2016 Oct 19. doi: 10.1182/blood-2016-06-723783

PMCID:: PMC5159706

Abstract Article

Select item 515494610.

Specific niches for lung-resident memory CD8⁺ T cells at the site of tissue regeneration enable CD69-independent maintenance

Shiki Takamura, Hideki Yagi, Yoshiyuki Hakata, Chihiro Motozono, Sean R. McMaster, Tomoko Masumoto, Makoto Fujisawa, Tomomi Chikaishi, Junko Komeda, Jun Itoh, Miki Umemura, Ami Kyusai, Michio Tomura, Toshinori Nakayama, David L. Woodland, Jacob E. Kohlmeier, Masaaki Miyazawa

J Exp Med. 2016 Dec 12; 213(13): 3057–3073. doi: 10.1084/jem.20160938

PMCID:: PMC5154946

Abstract Article PDF–3.5M

Select item 514664011.

CD69 controls L-Trp uptake through LAT1-CD98 and AhR-dependent IL-22 secretion in psoriasis

Danay Cibrián Vera, María Laura Saiz, Hortensia de la Fuente, Raquel Sánchez-Díaz, Olga Moreno-Gonzalo, Inmaculada Jorge Cerrudo, Alessia Ferrarini, Jesús Vázquez, Carmen Punzón, Manuel Fresno, Miguel Vicente-Manzanares, Esteban Daudén Tello, Pedro M. Fernández-Salguero, Pilar Martín, Francisco Sánchez-Madrid

Nat Immunol. Author manuscript; available in PMC 2017 Feb 1.

Published in final edited form as: Nat Immunol. 2016 Aug; 17(8): 985–996. Published online 2016 Jul 4. doi: 10.1038/ni.3504

Correction in:: Nat Immunol. 2016 Sep 20; 17(10): 1235.

PMCID:: PMC5146640

Abstract Article PDF–3.5M

Select item 511847712.

Immune-Regulatory Molecule CD69 Controls Peritoneal Fibrosis

Georgios Liappas, Guadalupe Tirma González-Mateo, Raquel Sánchez-Díaz, Juan José Lazcano, Sandra Lasarte, Adela Matesanz-Marín, Rafal Zur, Evelina Ferrantelli, Laura García Ramírez, Abelardo Aguilera, Elena Fernández-Ruiz, Robert H.J. Beelen, Rafael Selgas, Francisco Sánchez-Madrid, Pilar Martín, Manuel López-Cabrera

J Am Soc Nephrol. 2016 Dec; 27(12): 3561–3576. Published online 2016 May 5. doi: 10.1681/ASN.2015080909

PMCID:: PMC5118477

Abstract Article

Select item 498209613.

IL‐18‐induced expression of high‐affinity IL‐2R on murine NK cells is essential for NK‐cell IFN‐γ production during murine Plasmodium yoelii infection

Kerstin A. Stegmann, J. Brian De Souza, Eleanor M. Riley

Eur J Immunol. 2015 Dec; 45(12): 3431–3440. Published online 2015 Oct 21. doi: 10.1002/eji.201546018

PMCID:: PMC4982096

Abstract Article PDF–1.4M

Select item 493612414.

CD69 Deficiency Enhances the Host Response to Vaccinia Virus Infection through Altered NK Cell Homeostasis

Laura Notario, Elisenda Alari-Pahissa, Antonio de Molina, Pilar Lauzurica

J Virol. 2016 Jul 15; 90(14): 6464–6474. Prepublished online 2016 May 4. Published online 2016 Jun 24. doi: 10.1128/JVI.00550-16

PMCID:: PMC4936124

Abstract Article PDF–3.5M

Select item 469047215.

A map of sphingosine 1-phosphate distribution in the spleen

Willy D. Ramos-Perez, Victoria Fang, Diana Escalante-Alcalde, Michael Cammer, Susan R. Schwab

Nat Immunol. Author manuscript; available in PMC 2016 May 18.

Published in final edited form as: Nat Immunol. 2015 Dec; 16(12): 1245–1252. Published online 2015 Oct 26. doi: 10.1038/ni.3296

PMCID:: PMC4690472

Abstract Article PDF–1.5M

Select item 462561016.

Maintenance of immune tolerance by Foxp3⁺ regulatory T cells requires CD69 expression

José R. Cortés, Raquel Sánchez-Díaz, Elena R. Bovolenta, Olga Barreiro, Sandra Lasarte, Adela Matesanz-Marín, María L. Toribio, Francisco Sánchez-Madrid, Pilar Martín

J Autoimmun. Author manuscript; available in PMC 2015 Dec 1.

Published in final edited form as: J Autoimmun. 2014 Dec; 55: 51–62. Published online 2014 Jun 14. doi: 10.1016/j.jaut.2014.05.007

PMCID:: PMC4625610

Abstract Article PDF–2.5M

Select item 405430917.

The Leukocyte Activation Receptor CD69 Controls T Cell Differentiation through Its Interaction with Galectin-1

Hortensia de la Fuente, Aranzazu Cruz-Adalia, Gloria Martinez del Hoyo, Danay Cibrián-Vera, Pedro Bonay, Daniel Pérez-Hernández, Jesús Vázquez, Pilar Navarro, Ricardo Gutierrez-Gallego, Marta Ramirez-Huesca, Pilar Martín, Francisco Sánchez-Madrid

Mol Cell Biol. 2014 Jul; 34(13): 2479–2487. doi: 10.1128/MCB.00348-14

PMCID:: PMC4054309

Abstract Article PDF–1.9M

Select item 401309118.

Stabilization and Augmentation of Circulating AIM in Mice by Synthesized IgM-Fc

Toshihiro Kai, Tomoko Yamazaki, Satoko Arai, Toru Miyazaki

PLoS One. 2014; 9(5): e97037. Published online 2014 May 7. doi: 10.1371/journal.pone.0097037

PMCID:: PMC4013091

Abstract Article PDF–4.2M

Select item 395643219.

A ZAP-70 kinase domain variant prevents thymocyte-positive selection despite signalling CD69 induction

Owen M Siggs, Adèle L Yates, Susan Schlenner, Adrian Liston, Sylvie Lesage, Christopher C Goodnow

Immunology. 2014 Apr; 141(4): 587–595. Published online 2014 Mar 11. doi: 10.1111/imm.12220

PMCID:: PMC3956432

Abstract Article PDF–641K

Select item 368181620.

Crucial Role for CD69 in the Pathogenesis of Dextran Sulphate Sodium-Induced Colitis

Akihiro Hasegawa, Chiaki Iwamura, Masayuki Kitajima, Kahoko Hashimoto, Ken-ichiro Otsuyama, Hidetaka Ogino, Toshinori Nakayama, Mutsunori Shirai

PLoS One. 2013; 8(6): e65494. Published online 2013 Jun 13. doi: 10.1371/journal.pone.0065494

PMCID:: PMC3681816

Abstract Article PDF–6.0M

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