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Items: 1 to 20 of 23

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Loss of Ptpmt1 limits mitochondrial utilization of carbohydrates and leads to muscle atrophy and heart failure in tissue-specific knockout mice
Hong Zheng, Qianjin Li, Shanhu Li, Zhiguo Li, Marco Brotto, Daiana Weiss, Domenick Prosdocimo, Chunhui Xu, Ashruth Reddy, Michelle Puchowicz, Xinyang Zhao, M Neale Weitzmann, Mukesh K Jain, Cheng-Kui Qu
eLife. 2023; 12: RP86944. Published online 2023 Sep 6. doi: 10.7554/eLife.86944
PMCID:
PMC10482430
AbstractArticlePDF–7.5M
3.
DELE1 is protective for mitochondrial cardiomyopathy
Helen Huynh, Siting Zhu, Sharon Lee, Yutong Bao, Jing Pang, Anh Nguyen, Yusu Gu, Chao Chen, Kunfu Ouyang, Sylvia M. Evans, Xi Fang
J Mol Cell Cardiol. Author manuscript; available in PMC 2023 Jul 30.
Published in final edited form as: J Mol Cell Cardiol. 2023 Feb; 175: 44–48. Published online 2022 Dec 17. doi: 10.1016/j.yjmcc.2022.12.003
PMCID:
PMC10387237
AbstractArticlePDF–661K
4.
Mitochondrial stress induces an HRI-eIF2α pathway protective for cardiomyopathy
Siting Zhu, Anh Nguyen, Jing Pang, Jun Zhao, Ze’e Chen, Zhengyu Liang, Yusu Gu, Helen Huynh, Yutong Bao, Sharon Lee, Yuval Kluger, Kunfu Ouyang, Sylvia M Evans, Xi Fang
Circulation. Author manuscript; available in PMC 2023 Sep 27.
Published in final edited form as: Circulation. 2022 Sep 27; 146(13): 1028–1031. Published online 2022 Sep 26. doi: 10.1161/CIRCULATIONAHA.122.059594
PMCID:
PMC9523491
ArticlePDF–1016K
5.
PTPMT1 is required for embryonic cardiac cardiolipin biosynthesis to regulate mitochondrial morphogenesis and heart development
Ze’e Chen, Siting Zhu, Hong Wang, Li Wang, Jianlin Zhang, Yusu Gu, Changming Tan, Mehul Dhanani, Eric Wever, Xinru Wang, Boyu Xie, Shijia Wang, Lei Huang, Antoine H.C. van Kampen, Jie Liu, Zhen Han, Hemal H. Patel, Frédéric M. Vaz, Xi Fang, Ju Chen, Kunfu Ouyang
Circulation. Author manuscript; available in PMC 2022 Aug 3.
Published in final edited form as: Circulation. 2021 Aug 3; 144(5): 403–406. Published online 2021 Aug 2. doi: 10.1161/CIRCULATIONAHA.121.054768
PMCID:
PMC8340985
ArticlePDF–1.0M
6.
Dynamic Cardiolipin Synthesis Is Required for CD8+ T Cell Immunity
Mauro Corrado, Joy Edwards-Hicks, Matteo Villa, Lea J. Flachsmann, David E. Sanin, Maaike Jacobs, Francesc Baixauli, Michal Stanczak, Eve Anderson, Mai Azuma, Andrea Quintana, Jonathan D. Curtis, Thomas Clapes, Katarzyna M. Grzes, Agnieszka M. Kabat, Ryan Kyle, Annette E. Patterson, Ramon Klein Geltink, Borko Amulic, Colin G. Steward, Douglas Strathdee, Eirini Trompouki, David O’Sullivan, Edward J. Pearce, Erika L. Pearce
Cell Metab. 2020 Dec 1; 32(6): 981–995.e7. doi: 10.1016/j.cmet.2020.11.003
PMCID:
PMC7721104
AbstractArticle
7.
Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors
Hyeonwoo Kim, Christiane D. Wrann, Mark Jedrychowski, Sara Vidoni, Yukiko Kitase, Kenichi Nagano, Chenhe Zhou, Joshua Chou, Virginia-Jeni A. Parkman, Scott J. Novick, Timothy S. Strutzenberg, Bruce D. Pascal, Phuong T. Le, Daniel J. Brooks, Alexander M. Roche, Kaitlyn K. Gerber, Laura Mattheis, Wenjing Chen, Hua Tu, Mary L. Bouxsein, Patrick R. Griffin, Roland Baron, Clifford J. Rosen, Lynda F. Bonewald, Bruce M. Spiegelman
Cell. Author manuscript; available in PMC 2019 Dec 13.
Published in final edited form as: Cell. 2018 Dec 13; 175(7): 1756–1768.e17. doi: 10.1016/j.cell.2018.10.025
Correction in:
Cell. 2019 Jul 11; 178(2): 507–508.
PMCID:
PMC6298040
AbstractArticlePDF–1.2M
8.
Mitochondrial oxidation of the carbohydrate fuel is required for neural precursor/stem cell function and postnatal cerebellar development
Hong Zheng, Wen-Mei Yu, Jinhua Shen, Sumin Kang, Dolores Hambardzumyan, James Y. Li, Yuxian Shen, Anna M. Kenney, Jing Chen, Cheng-Kui Qu
Sci Adv. 2018 Oct; 4(10): eaat2681. Published online 2018 Oct 10. doi: 10.1126/sciadv.aat2681
PMCID:
PMC6191298
AbstractArticlePDF–3.6M
9.
High-throughput discovery of novel developmental phenotypes
Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M. Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R. Horner, Chih-wei Hsu, Sara J. Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M.J. Nutter, Kevin A. Peterson, Ramiro Ramirez-Solis, Douglas J. Rowland, Edward Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Daniel G. MacArthur, Glauco P. Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen E. Parkinson, Mark Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R. Mark Henkelman, Steve D.M. Brown, David J. Adams, K.C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bucan, Stephen A. Murray
Nature. Author manuscript; available in PMC 2017 Mar 14.
Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 508–514. Published online 2016 Sep 14. doi: 10.1038/nature19356
Correction in:
Nature. 2017 Nov 16; 551(7680): 398.
PMCID:
PMC5295821
AbstractArticlePDF–3.0M
10.
The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data
Gautier Koscielny, Gagarine Yaikhom, Vivek Iyer, Terrence F. Meehan, Hugh Morgan, Julian Atienza-Herrero, Andrew Blake, Chao-Kung Chen, Richard Easty, Armida Di Fenza, Tanja Fiegel, Mark Grifiths, Alan Horne, Natasha A. Karp, Natalja Kurbatova, Jeremy C. Mason, Peter Matthews, Darren J. Oakley, Asfand Qazi, Jack Regnart, Ahmad Retha, Luis A. Santos, Duncan J. Sneddon, Jonathan Warren, Henrik Westerberg, Robert J. Wilson, David G. Melvin, Damian Smedley, Steve D. M. Brown, Paul Flicek, William C. Skarnes, Ann-Marie Mallon, Helen Parkinson
Nucleic Acids Res. 2014 Jan 1; 42(Database issue): D802–D809. Published online 2013 Nov 3. doi: 10.1093/nar/gkt977
PMCID:
PMC3964955
AbstractArticlePDF–5.7M
11.
Metabolic Regulation by the Mitochondrial Phosphatase PTPMT1 Is Required for Hematopoietic Stem Cell Differentiation
Wen-Mei Yu, Xia Liu, Jinhua Shen, Olga Jovanovic, Elena E. Pohl, Stanton L. Gerson, Toren Finkel, Hal E. Broxmeyer, Cheng-Kui Qu
Cell Stem Cell. Author manuscript; available in PMC 2014 Jan 3.
Published in final edited form as: Cell Stem Cell. 2013 Jan 3; 12(1): 62–74. doi: 10.1016/j.stem.2012.11.022
PMCID:
PMC3632072
AbstractArticlePDF–3.5M
12.
A Critical Role of Mitochondrial Phosphatase Ptpmt1 in Embryogenesis Reveals a Mitochondrial Metabolic Stress-Induced Differentiation Checkpoint in Embryonic Stem Cells
Jinhua Shen, Xia Liu, Wen-Mei Yu, Jie Liu, Milou Groot Nibbelink, Caiying Guo, Toren Finkel, Cheng-Kui Qu
Mol Cell Biol. 2011 Dec; 31(24): 4902–4916. doi: 10.1128/MCB.05629-11
PMCID:
PMC3233018
AbstractArticlePDF–3.6M
13.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
14.
Mitochondrial Phosphatase PTPMT1 is essential for cardiolipin biosynthesis
Ji Zhang, Ziqiang Guan, Anne N. Murphy, Sandra E. Wiley, Guy A. Perkins, Carolyn A. Worby, James L. Engel, Philip Heacock, Oanh Kim Nguyen, Jonathan H. Wang, Christian R.H. Raetz, William Dowhan, Jack E. Dixon
Cell Metab. Author manuscript; available in PMC 2012 Jun 8.
Published in final edited form as: Cell Metab. 2011 Jun 8; 13(6): 690–700. doi: 10.1016/j.cmet.2011.04.007
PMCID:
PMC3119201
AbstractArticlePDF–3.2M
15.
A mitochondrial protein compendium elucidates complex I disease biology
David J. Pagliarini, Sarah E. Calvo, Betty Chang, Sunil A. Sheth, Scott B. Vafai, Shao-En Ong, Geoffrey A. Walford, Canny Sugiana, Avihu Boneh, William K. Chen, David E. Hill, Marc Vidal, James G. Evans, David R. Thorburn, Steven A. Carr, Vamsi K. Mootha
Cell. Author manuscript; available in PMC 2009 Nov 18.
Published in final edited form as: Cell. 2008 Jul 11; 134(1): 112–123. doi: 10.1016/j.cell.2008.06.016
PMCID:
PMC2778844
AbstractArticlePDF–1.2M
16.
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells
Gwenn M. Hansen, Diane C. Markesich, Michael B. Burnett, Qichao Zhu, Karen M. Dionne, Lizabeth J. Richter, Richard H. Finnell, Arthur T. Sands, Brian P. Zambrowicz, Alejandro Abuin
Genome Res. 2008 Oct; 18(10): 1670–1679. doi: 10.1101/gr.078352.108
PMCID:
PMC2556270
AbstractArticlePDF–493K
17.
Dual Specificity Phosphatases 18 and 21 Target to Opposing Sides of the Mitochondrial Inner Membrane
Matthew J. Rardin, Sandra E. Wiley, Anne N. Murphy, David J. Pagliarini, Jack E. Dixon
J Biol Chem. 2008 May 30; 283(22): 15440–15450. doi: 10.1074/jbc.M709547200
PMCID:
PMC2397459
AbstractArticlePDF–1.9M
18.
MitoNEET is an iron-containing outer mitochondrial membrane protein that regulates oxidative capacity
Sandra E. Wiley, Anne N. Murphy, Stuart A. Ross, Peter van der Geer, Jack E. Dixon
Proc Natl Acad Sci U S A. 2007 Mar 27; 104(13): 5318–5323. Published online 2007 Mar 21. doi: 10.1073/pnas.0701078104
PMCID:
PMC1838440
AbstractArticlePDF–1.6M
19.
The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)
Genome Res. 2004 Oct; 14(10b): 2121–2127. doi: 10.1101/gr.2596504
Correction in:
Genome Res. 2006 Jun; 16(6): 804.
PMCID:
PMC528928
AbstractArticlePDF–140K
20.
RIKEN Integrated Sequence Analysis (RISA) System—384-Format Sequencing Pipeline with 384 Multicapillary Sequencer
Kazuhiro Shibata, Masayoshi Itoh, Katsunori Aizawa, Sumiharu Nagaoka, Nobuya Sasaki, Piero Carninci, Hideaki Konno, Junichi Akiyama, Katsuo Nishi, Tokuji Kitsunai, Hideo Tashiro, Mari Itoh, Noriko Sumi, Yoshiyuki Ishii, Shin Nakamura, Makoto Hazama, Tsutomu Nishine, Akira Harada, Rintaro Yamamoto, Hiroyuki Matsumoto, Sumito Sakaguchi, Takashi Ikegami, Katsuya Kashiwagi, Syuji Fujiwake, Kouji Inoue, Yoshiyuki Togawa, Masaki Izawa, Eiji Ohara, Masanori Watahiki, Yuko Yoneda, Tomokazu Ishikawa, Kaori Ozawa, Takumi Tanaka, Shuji Matsuura, Jun Kawai, Yasushi Okazaki, Masami Muramatsu, Yorinao Inoue, Akira Kira, Yoshihide Hayashizaki
Genome Res. 2000 Nov; 10(11): 1757–1771. doi: 10.1101/gr.152600
PMCID:
PMC310992
AbstractArticlePDF–3.4M

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