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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 100388982.

A knockout-first model of H3f3a gene targeting leads to developmental lethality

Kelly Bush, Vanessa Cervantes, Jennifer Q. Yee, Rachel H. Klein, Paul S. Knoepfler

Genesis. Author manuscript; available in PMC 2023 Mar 25.

Published in final edited form as: Genesis. 2023 Mar; 61(1-2): e23507. Published online 2023 Jan 19. doi: 10.1002/dvg.23507

PMCID:: PMC10038898

Abstract Article PDF–968K

Select item 99768893.

PRC2-independent actions of H3.3K27M in embryonic stem cell differentiation

Lea R Z Cohen, Binyamin Kaffe, Eden Deri, Chen Leibson, Malka Nissim-Rafinia, Moria Maman, Nofar Harpaz, Guy Ron, Efrat Shema, Eran Meshorer

Nucleic Acids Res. 2023 Feb 28; 51(4): 1662–1673. Published online 2022 Sep 26. doi: 10.1093/nar/gkac800

Correction in:: Nucleic Acids Res. 2023 Feb 28; 51(4): 1996.

PMCID:: PMC9976889

Abstract Article PDF–3.9M

Select item 93717314.

Postmitotic accumulation of histone variant H3.3 in new cortical neurons establishes neuronal chromatin, transcriptome, and identity

Owen H. Funk, Yaman Qalieh, Daniel Z. Doyle, Mandy M. Lam, Kenneth Y. Kwan

Proc Natl Acad Sci U S A. 2022 Aug 9; 119(32): e2116956119. Published online 2022 Aug 5. doi: 10.1073/pnas.2116956119

PMCID:: PMC9371731

Abstract Article PDF–7.3M

Select item 93491745.

Histone H3K36me2 and H3K36me3 form a chromatin platform essential for DNMT3A-dependent DNA methylation in mouse oocytes

Seiichi Yano, Takashi Ishiuchi, Shusaku Abe, Satoshi H. Namekawa, Gang Huang, Yoshihiro Ogawa, Hiroyuki Sasaki

Nat Commun. 2022; 13: 4440. Published online 2022 Aug 3. doi: 10.1038/s41467-022-32141-2

PMCID:: PMC9349174

Abstract Article PDF–3.3M

Select item 93033866.

Dual role of histone variant H3.3B in spermatogenesis: positive regulation of piRNA transcription and implication in X-chromosome inactivation

Emeline Fontaine, Christophe Papin, Guillaume Martinez, Stéphanie Le Gras, Roland Abi Nahed, Patrick Héry, Thierry Buchou, Khalid Ouararhni, Bertrand Favier, Thierry Gautier, Jamal S M Sabir, Matthieu Gerard, Jan Bednar, Christophe Arnoult, Stefan Dimitrov, Ali Hamiche

Nucleic Acids Res. 2022 Jul 22; 50(13): 7350–7366. Published online 2022 Jun 29. doi: 10.1093/nar/gkac541

PMCID:: PMC9303386

Abstract Article PDF–8.5M

Select item 91669357.

Histone variant H3.3 maintains adult haematopoietic stem cell homeostasis by enforcing chromatin adaptability

Peipei Guo, Ying Liu, Fuqiang Geng, Andrew W. Daman, Xiaoyu Liu, Liangwen Zhong, Arjun Ravishankar, Raphael Lis, José Gabriel Barcia Durán, Tomer Itkin, Fanying Tang, Tuo Zhang, Jenny Xiang, Koji Shido, Bi-sen Ding, Duancheng Wen, Steven Z. Josefowicz, Shahin Rafii

Nat Cell Biol. Author manuscript; available in PMC 2022 Jun 4.

Published in final edited form as: Nat Cell Biol. 2022 Jan; 24(1): 99–111. Published online 2021 Dec 27. doi: 10.1038/s41556-021-00795-7

PMCID:: PMC9166935

Abstract Article PDF–7.7M

Select item 90714038.

Histone H3.3 phosphorylation promotes heterochromatin formation by inhibiting H3K9/K36 histone demethylase

Maheshi Udugama, Benjamin Vinod, F Lyn Chan, Linda Hii, Andrew Garvie, Philippe Collas, Paul Kalitsis, David Steer, Partha P Das, Pratibha Tripathi, Jeffrey R Mann, Hsiao P J Voon, Lee H Wong

Nucleic Acids Res. 2022 May 6; 50(8): 4500–4514. Published online 2022 Apr 22. doi: 10.1093/nar/gkac259

PMCID:: PMC9071403

Abstract Article PDF–17M

Select item 90185849.

Gag‐like proteins: Novel mediators of prenatal alcohol exposure in neural development

Marisa R. Pinson, Dae D. Chung, Amanda H. Mahnke, Nihal A. Salem, Daniel Osorio, Vijay Nair, Elizabeth A. Payne, Jonathan J. del Real, James J. Cai, Rajesh C. Miranda

Alcohol Clin Exp Res. 2022 Apr; 46(4): 556–569. Published online 2022 Mar 2. doi: 10.1111/acer.14796

PMCID:: PMC9018584

Abstract Article PDF–1.8M

Select item 851061310.

A histone H3.3K36M mutation in mice causes an imbalance of histone modifications and defects in chondrocyte differentiation

Shusaku Abe, Hiroaki Nagatomo, Hiroyuki Sasaki, Takashi Ishiuchi

Epigenetics. 2021; 16(10): 1123–1134. Published online 2020 Nov 16. doi: 10.1080/15592294.2020.1841873

PMCID:: PMC8510613

Abstract Article PDF–7.2M

Select item 831323911.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 795255212.

Profiling of three H3F3A-mutated and denosumab-treated giant cell tumors of bone points to diverging pathways during progression and malignant transformation

Marc Hasenfratz, Kevin Mellert, Ralf Marienfeld, Alexandra von Baer, Markus Schultheiss, P. D. Roitman, L. A. Aponte-Tinao, Burkhard Lehner, Peter Möller, Gunhild Mechtersheimer, Thomas F. E. Barth

Sci Rep. 2021; 11: 5709. Published online 2021 Mar 11. doi: 10.1038/s41598-021-85319-x

PMCID:: PMC7952552

Abstract Article PDF–2.1M

Select item 772242613.

Effects of H3.3G34V mutation on genomic H3K36 and H3K27 methylation patterns in isogenic pediatric glioma cells

Tina Yi-Ting Huang, Andrea Piunti, Jin Qi, Marc Morgan, Elizabeth Bartom, Ali Shilatifard, Amanda M. Saratsis

Acta Neuropathol Commun. 2020; 8: 219. Published online 2020 Dec 7. doi: 10.1186/s40478-020-01092-4

PMCID:: PMC7722426

Abstract Article PDF–3.0M

Select item 754708714.

An embryonic stem cell-specific heterochromatin state promotes core histone exchange in the absence of DNA accessibility

Carmen Navarro, Jing Lyu, Anna-Maria Katsori, Rozina Caridha, Simon J. Elsässer

Nat Commun. 2020; 11: 5095. Published online 2020 Oct 9. doi: 10.1038/s41467-020-18863-1

PMCID:: PMC7547087

Abstract Article PDF–5.2M

Select item 722439415.

Transcription factor TEAD1 is essential for vascular development by promoting vascular smooth muscle differentiation

Tong Wen, Jinhua Liu, Xiangqin He, Kunzhe Dong, Guoqing Hu, Luyi Yu, Qin Yin, Islam Osman, Jingtian Peng, Zeqi Zheng, Hongbo Xin, David Fulton, Quansheng Du, Wei Zhang, Jiliang Zhou

Cell Death Differ. 2019 Dec; 26(12): 2790–2806. Published online 2019 Apr 25. doi: 10.1038/s41418-019-0335-4

PMCID:: PMC7224394

Abstract Article PDF–6.5M

Select item 721203616.

KDM4A regulates the maternal-to-zygotic transition by protecting broad H3K4me3 domains from H3K9me3 invasion in oocytes

Aditya Sankar, Mads Lerdrup, Adeel Manaf, Jens Vilstrup Johansen, Javier Martin Gonzalez, Rehannah Borup, Robert Blanshard, Arne Klungland, Klaus Hansen, Claus Yding Andersen, John Arne Dahl, Kristian Helin, Eva R. Hoffmann

Nat Cell Biol. Author manuscript; available in PMC 2020 Sep 30.

Published in final edited form as: Nat Cell Biol. 2020 Apr 1; 22(4): 380–388. Published online 2020 Mar 30. doi: 10.1038/s41556-020-0494-z

PMCID:: PMC7212036

Abstract Article PDF–5.2M

Select item 672539417.

Telencephalic Embryonic Subtractive Sequences: A Unique Collection of Neurodevelopmental Genes

Alessandro Bulfone, Pietro Carotenuto, Andrea Faedo, Veruska Aglio, Livia Garzia, Anna Maria Bello, Andrea Basile, Alessandra Andrè, Massimo Cocchia, Ombretta Guardiola, Andrea Ballabio, John L. R. Rubenstein, Massimo Zollo

J Neurosci. 2005 Aug 17; 25(33): 7586–7600. doi: 10.1523/JNEUROSCI.0522-05.2005

PMCID:: PMC6725394

Abstract Article PDF–682K

Select item 661958618.

Nuclear Factor κB-Dependent Histone Acetylation is Specifically Involved in Persistent Forms of Memory

Noel Federman, Verónica de la Fuente, Gisela Zalcman, Nicoletta Corbi, Annalisa Onori, Claudio Passananti, Arturo Romano

J Neurosci. 2013 Apr 24; 33(17): 7603–7614. doi: 10.1523/JNEUROSCI.4181-12.2013

PMCID:: PMC6619586

Abstract Article PDF–3.4M

Select item 636930719.

A versatile mouse model of epitope-tagged histone H3.3 to study epigenome dynamics

Mahesh Bachu, Tomohiko Tamura, Chao Chen, Ankur Narain, Vishal Nehru, Naoyuki Sarai, Sukhendu B. Ghosh, Anu Ghosh, Raghuveer Kavarthapu, Maria L. Dufau, Keiko Ozato

J Biol Chem. 2019 Feb 8; 294(6): 1904–1914. Published online 2018 Dec 14. doi: 10.1074/jbc.RA118.005550

PMCID:: PMC6369307

Abstract Article PDF–6.2M

Select item 634668520.

Plasticity in the Glucagon Interactome Reveals Novel Proteins That Regulate Glucagon Secretion in α-TC1-6 Cells

Farzad Asadi, Savita Dhanvantari

Front Endocrinol (Lausanne) 2018; 9: 792. Published online 2019 Jan 18. doi: 10.3389/fendo.2018.00792

PMCID:: PMC6346685

Abstract Article PDF–3.6M

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