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Select item 83802141.

GABA_A receptors: structure, function, pharmacology, and related disorders

Amr Ghit, Dina Assal, Ahmed S. Al-Shami, Diaa Eldin E. Hussein

J Genet Eng Biotechnol. 2021 Dec; 19: 123. Published online 2021 Aug 21. doi: 10.1186/s43141-021-00224-0

PMCID:: PMC8380214

Abstract Article PDF–1016K

Select item 82568842.

Intrasubunit and Intersubunit Steroid Binding Sites Independently and Additively Mediate α1β2γ2L GABA_A Receptor Potentiation by the Endogenous Neurosteroid Allopregnanolone

Allison L. Germann, Spencer R. Pierce, Hiroki Tateiwa, Yusuke Sugasawa, David E. Reichert, Alex S. Evers, Joe Henry Steinbach, Gustav Akk

Mol Pharmacol. 2021 Jul; 100(1): 19–31. Published online 2021 Jul. doi: 10.1124/molpharm.121.000268

PMCID:: PMC8256884

Abstract Article PDF–1.7M

Select item 74866243.

Local miRNA-Dependent Translational Control of GABA_AR Synthesis during Inhibitory Long-Term Potentiation

Dipen Rajgor, Alicia M. Purkey, Jennifer L. Sanderson, Theresa M. Welle, Joshua D. Garcia, Mark L. Dell’Acqua, Katharine R. Smith

Cell Rep. Author manuscript; available in PMC 2020 Sep 12.

Published in final edited form as: Cell Rep. 2020 Jun 23; 31(12): 107785. doi: 10.1016/j.celrep.2020.107785

PMCID:: PMC7486624

Abstract Article PDF–3.1M

Select item 67953084.

α₁F64 Residue at GABA_A Receptor Binding Site Is Involved in Gating by Influencing the Receptor Flipping Transitions

Marcin Szczot, Magdalena Kisiel, Marta M. Czyzewska, Jerzy W. Mozrzymas

J Neurosci. 2014 Feb 26; 34(9): 3193–3209. doi: 10.1523/JNEUROSCI.2533-13.2014

Correction in:: J Neurosci. 2016 Feb 10; 36(6): 2074.

PMCID:: PMC6795308

Abstract Article PDF–3.7M

Select item 67926115.

Segregation of Different GABA_A Receptors to Synaptic and Extrasynaptic Membranes of Cerebellar Granule Cells

Zoltan Nusser, Werner Sieghart, Peter Somogyi

J Neurosci. 1998 Mar 1; 18(5): 1693–1703. doi: 10.1523/JNEUROSCI.18-05-01693.1998

PMCID:: PMC6792611

Abstract Article PDF–1.4M

Select item 67419016.

Interaction of Calcineurin and Type-A GABA Receptor γ₂ Subunits Produces Long-Term Depression at CA1 Inhibitory Synapses

Jian Wang, ShuHong Liu, Ursula Haditsch, WeiHong Tu, Kimberley Cochrane, Gholamreza Ahmadian, Linda Tran, Jadine Paw, YuTian Wang, Isabelle Mansuy, Michael M. Salter, YouMing Lu

J Neurosci. 2003 Feb 1; 23(3): 826–836. doi: 10.1523/JNEUROSCI.23-03-00826.2003

PMCID:: PMC6741901

Abstract Article PDF–571K

Select item 67297127.

Slow Actions of Neuroactive Steroids at GABA_A Receptors

Hong-Jin Shu, Lawrence N. Eisenman, Deepani Jinadasa, Douglas F. Covey, Charles F. Zorumski, Steven Mennerick

J Neurosci. 2004 Jul 28; 24(30): 6667–6675. doi: 10.1523/JNEUROSCI.1399-04.2004

PMCID:: PMC6729712

Abstract Article PDF–268K

Select item 66735148.

GABA_A Receptor γ2 Subunit Mutations Linked to Human Epileptic Syndromes Differentially Affect Phasic and Tonic Inhibition

Emmanuel Eugène, Christel Depienne, Stéphanie Baulac, Michel Baulac, Jean Marc Fritschy, Eric Le Guern, Richard Miles, Jean Christophe Poncer

J Neurosci. 2007 Dec 19; 27(51): 14108–14116. doi: 10.1523/JNEUROSCI.2618-07.2007

PMCID:: PMC6673514

Abstract Article PDF–434K

Select item 66732539.

Mechanisms of Reversible GABA_A Receptor Plasticity after Ethanol Intoxication

Jing Liang, Asha Suryanarayanan, Alana Abriam, Bradley Snyder, Richard W. Olsen, Igor Spigelman

J Neurosci. 2007 Nov 7; 27(45): 12367–12377. doi: 10.1523/JNEUROSCI.2786-07.2007

PMCID:: PMC6673253

Abstract Article PDF–9.4M

Select item 657605910.

The distribution of 13 GABAA receptor subunit mRNAs in the rat brain. I. Telencephalon, diencephalon, mesencephalon

W Wisden, DJ Laurie, H Monyer, PH Seeburg

J Neurosci. 1992 Mar 1; 12(3): 1040–1062. doi: 10.1523/JNEUROSCI.12-03-01040.1992

PMCID:: PMC6576059

Abstract PDF–6.5M

Select item 657604011.

The distribution of 13 GABAA receptor subunit mRNAs in the rat brain. II. Olfactory bulb and cerebellum

DJ Laurie, PH Seeburg, W Wisden

J Neurosci. 1992 Mar 1; 12(3): 1063–1076. doi: 10.1523/JNEUROSCI.12-03-01063.1992

PMCID:: PMC6576040

Abstract PDF–3.7M

Select item 657036512.

Functional characteristics and sites of gene expression of the alpha 1, beta 1, gamma 2-isoform of the rat GABAA receptor

P Malherbe, E Sigel, R Baur, E Persohn, JG Richards, H Mohler

J Neurosci. 1990 Jul 1; 10(7): 2330–2337. doi: 10.1523/JNEUROSCI.10-07-02330.1990

PMCID:: PMC6570365

Abstract PDF–1.1M

Select item 636480713.

Cryo-EM structure of the human α1β3γ2 GABA_A receptor in a lipid bilayer

Duncan Laverty, Rooma Desai, Tomasz Uchański, Simonas Masiulis, Wojciech J. Stec, Tomas Malinauskas, Jasenko Zivanov, Els Pardon, Jan Steyaert, Keith W. Miller, A. Radu Aricescu

Nature. Author manuscript; available in PMC 2019 Jul 2.

Published in final edited form as: Nature. 2019 Jan 2 : 10.1038/s41586-018-0833-4. doi: 10.1038/s41586-018-0833-4

PMCID:: PMC6364807

Abstract Article PDF–7.2M

Select item 622070814.

Structure of a human synaptic GABA-A receptor

Shaotong Zhu, Colleen M. Noviello, Jinfeng Teng, Richard M. Walsh, Jr., Jeong Joo Kim, Ryan E. Hibbs

Nature. Author manuscript; available in PMC 2018 Dec 27.

Published in final edited form as: Nature. 2018 Jul; 559(7712): 67–72. Published online 2018 Jun 27. doi: 10.1038/s41586-018-0255-3

PMCID:: PMC6220708

Abstract Article PDF–6.8M

Select item 574362015.

Examining the Effects of Alcohol on GABA_A Receptor mRNA Expression and Function in Neural Cultures Generated from Control and Alcohol Dependent Donor Induced Pluripotent Stem Cells

Richard Lieberman, Henry R. Kranzler, Eric S. Levine, Jonathan Covault

Alcohol. Author manuscript; available in PMC 2019 Feb 1.

Published in final edited form as: Alcohol. 2018 Feb; 66: 45–53. Published online 2017 Aug 12. doi: 10.1016/j.alcohol.2017.08.005

PMCID:: PMC5743620

Abstract Article PDF–705K

Select item 534747316.

GARLH family proteins stabilize GABA_A receptors at synapses

Tokiwa Yamasaki, Erika Hoyos-Ramirez, James S. Martenson, Megumi Morimoto-Tomita, Susumu Tomita

Neuron. Author manuscript; available in PMC 2018 Mar 8.

Published in final edited form as: Neuron. 2017 Mar 8; 93(5): 1138–1152.e6. doi: 10.1016/j.neuron.2017.02.023

PMCID:: PMC5347473

Abstract Article PDF–2.3M

Select item 493315417.

γ-Aminobutyric Acid Type A (GABA_A) Receptor Subunits Play a Direct Structural Role in Synaptic Contact Formation via Their N-terminal Extracellular Domains

Laura E. Brown, Martin W. Nicholson, Jessica E. Arama, Audrey Mercer, Alex M. Thomson, Jasmina N. Jovanovic

J Biol Chem. 2016 Jul 1; 291(27): 13926–13942. Published online 2016 Apr 20. doi: 10.1074/jbc.M116.714790

PMCID:: PMC4933154

Abstract Article PDF–3.1M

Select item 455901818.

Downregulation of Gabra4 expression during alcohol withdrawal is mediated by specific microRNAs in cultured mouse cortical neurons

Rola A Bekdash, Neil L Harrison

Brain Behav. 2015 Aug; 5(8): e00355. Published online 2015 Jun 2. doi: 10.1002/brb3.355

PMCID:: PMC4559018

Abstract Article PDF–2.4M

Select item 435409819.

Inhibitory Synapse Formation in a Co-culture Model Incorporating GABAergic Medium Spiny Neurons and HEK293 Cells Stably Expressing GABA_A Receptors

Laura E. Brown, Celine Fuchs, Martin W. Nicholson, F. Anne Stephenson, Alex M. Thomson, Jasmina N. Jovanovic

J Vis Exp. 2014; (93): 52115. Published online 2014 Nov 14. doi: 10.3791/52115

PMCID:: PMC4354098

Abstract Article PDF–1.0M

Select item 431607420.

Expression of gamma-aminobutyric acid A receptor subunits α₁, β₁, γ₂ mRNA in rats with hepatic encephalopathy

Xiao-Qing Li, Lei Dong, Zhong-Hua Liu, Jin-Yan Luo

World J Gastroenterol. 2005 Jun 7; 11(21): 3319–3322. Published online 2005 Jun 7. doi: 10.3748/wjg.v11.i21.3319

PMCID:: PMC4316074

Abstract Article PDF–587K

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