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Select item 92956351.

Structure and Function of the Retina of Low-density Lipoprotein Receptor-related Protein 5 (Lrp5)-deficient Rats

John L. Ubels, Cheng-Mao Lin, David A. Antonetti, Monica Diaz-Coranguez, Cassandra R. Diegel, Bart O. Williams

Exp Eye Res. Author manuscript; available in PMC 2023 Apr 1.

Published in final edited form as: Exp Eye Res. 2022 Apr; 217: 108977. Published online 2022 Feb 6. doi: 10.1016/j.exer.2022.108977

PMCID:: PMC9295635

Abstract Article PDF–2.9M

Select item 82350972.

LRP5 Regulates HIF-1α Stability via Interaction with PHD2 in Ischemic Myocardium

Sujin Ju, Leejin Lim, Kwanhwan Wi, Changwon Park, Young-Jae Ki, Dong-Hyun Choi, Heesang Song

Int J Mol Sci. 2021 Jun; 22(12): 6581. Published online 2021 Jun 19. doi: 10.3390/ijms22126581

PMCID:: PMC8235097

Abstract Article PDF–7.4M

Select item 48165253.

Critical Endothelial Regulation by LRP5 during Retinal Vascular Development

Wei Huang, Qing Li, Mahmood Amiry-Moghaddam, Madoka Hokama, Sylvia H. Sardi, Masashi Nagao, Matthew L. Warman, Bjorn R. Olsen

PLoS One. 2016; 11(3): e0152833. Published online 2016 Mar 31. doi: 10.1371/journal.pone.0152833

PMCID:: PMC4816525

Abstract Article PDF–3.2M

Select item 47839674.

miR-9-5p, miR-675-5p and miR-138-5p Damages the Strontium and LRP5-Mediated Skeletal Cell Proliferation, Differentiation, and Adhesion

Tianhao Sun, Frankie Leung, William W. Lu

Int J Mol Sci. 2016 Feb; 17(2): 236. Published online 2016 Feb 15. doi: 10.3390/ijms17020236

PMCID:: PMC4783967

Abstract Article PDF–1.9M

Select item 47172085.

LRP5 variants may contribute to ADPKD

Wybrich R Cnossen, René HM te Morsche, Alexander Hoischen, Christian Gilissen, Hanka Venselaar, Soufi Mehdi, Carsten Bergmann, Monique Losekoot, Martijn H Breuning, Dorien JM Peters, Joris A Veltman, Joost PH Drenth

Eur J Hum Genet. 2016 Feb; 24(2): 237–242. Published online 2015 Apr 29. doi: 10.1038/ejhg.2015.86

PMCID:: PMC4717208

Abstract Article PDF–1.0M

Select item 46405056.

Missense Mutations in LRP5 Associated with High Bone Mass Protect the Mouse Skeleton from Disuse- and Ovariectomy-Induced Osteopenia

Paul J. Niziolek, Whitney Bullock, Matthew L. Warman, Alexander G. Robling

PLoS One. 2015; 10(11): e0140775. Published online 2015 Nov 10. doi: 10.1371/journal.pone.0140775

PMCID:: PMC4640505

Abstract Article PDF–1.9M

Select item 42591467.

WNT7b mediates macrophage-induced programmed cell death in patterning of the vasculature

Ivan B. Lobov, Sujata Rao, Thomas J. Carroll, Jefferson E. Vallance, Masataka Ito, Jennifer K. Ondr, Savita Kurup, Donald A. Glass, Millan S. Patel, Weiguo Shu, Edward E. Morrisey, Andrew P. McMahon, Gerard Karsenty, Richard A. Lang

Nature. Author manuscript; available in PMC 2014 Dec 8.

Published in final edited form as: Nature. 2005 Sep 15; 437(7057): 417–421. doi: 10.1038/nature03928

PMCID:: PMC4259146

Abstract Article PDF–590K

Select item 41307968.

Targeting the LRP5 pathway improves bone properties in a mouse model of Osteogenesis Imperfecta

Christina M. Jacobsen, Lauren A. Barber, Ugur M. Ayturk, Heather J. Roberts, Lauren E. Deal, Marissa A. Schwartz, MaryAnn Weis, David Eyre, David Zurakowski, Alexander G. Robling, Matthew L. Warman

J Bone Miner Res. Author manuscript; available in PMC 2015 Oct 1.

Published in final edited form as: J Bone Miner Res. 2014 Oct; 29(10): 2297–2306. doi: 10.1002/jbmr.2198

PMCID:: PMC4130796

Abstract Article PDF–523K

Select item 39861199.

Whole-exome sequencing reveals LRP5 mutations and canonical Wnt signaling associated with hepatic cystogenesis

Wybrich R. Cnossen, René H. M. te Morsche, Alexander Hoischen, Christian Gilissen, Melissa Chrispijn, Hanka Venselaar, Soufi Mehdi, Carsten Bergmann, Joris A. Veltman, Joost P. H. Drenth

Proc Natl Acad Sci U S A. 2014 Apr 8; 111(14): 5343–5348. Published online 2014 Mar 24. doi: 10.1073/pnas.1309438111

PMCID:: PMC3986119

Abstract Article PDF–912K

Select item 395185110.

Human Degenerative Valve Disease Is Associated With Up-Regulation of Low-Density Lipoprotein Receptor-Related Protein 5 Receptor-Mediated Bone Formation

Frank C. Caira, Stuart R. Stock, Thomas G. Gleason, Edwin C. McGee, Jie Huang, Robert O. Bonow, Thomas C. Spelsberg, Patrick M. McCarthy, Shahbudin H. Rahimtoola, Nalini M. Rajamannan

J Am Coll Cardiol. Author manuscript; available in PMC 2014 Mar 13.

Published in final edited form as: J Am Coll Cardiol. 2006 Apr 18; 47(8): 1707–1712. Published online 2006 Mar 20. doi: 10.1016/j.jacc.2006.02.040

PMCID:: PMC3951851

Abstract Article PDF–5.2M

Select item 383132211.

Anabolic steroids reduce spinal cord injury-related bone loss in rats associated with increased Wnt signaling

Li Sun, Jiangping Pan, Yuanzhen Peng, Yong Wu, Jianghua Li, Xuan Liu, Yiwen Qin, William A. Bauman, Christopher Cardozo, Mone Zaidi, Weiping Qin

J Spinal Cord Med. 2013 Nov; 36(6): 616–622. doi: 10.1179/2045772312Y.0000000020

PMCID:: PMC3831322

Abstract Article PDF–333K

Select item 337489012.

Mutations in LRP5 cause primary osteoporosis without features of OI by reducing Wnt signaling activity

Johanna Korvala, Harald Jüppner, Outi Mäkitie, Etienne Sochett, Dirk Schnabel, Stefano Mora, Cynthia F Bartels, Matthew L Warman, Donald Deraska, William G Cole, Heini Hartikka, Leena Ala-Kokko, Minna Männikkö

BMC Med Genet. 2012; 13: 26. Published online 2012 Apr 10. doi: 10.1186/1471-2350-13-26

PMCID:: PMC3374890

Abstract Article PDF–706K

Select item 317805913.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 290229314.

A model for familial exudative vitreoretinopathy caused by LPR5 mutations

Chun-Hong Xia, Haiquan Liu, Debra Cheung, Meng Wang, Catherine Cheng, Xin Du, Bo Chang, Bruce Beutler, Xiaohua Gong

Hum Mol Genet. 2008 Jun 1; 17(11): 1605–1612. Published online 2008 Feb 9. doi: 10.1093/hmg/ddn047

PMCID:: PMC2902293

Abstract Article PDF–816K

Select item 283829715.

Mechano-transduction in Osteoblastic Cells Involves Strain-regulated Estrogen Receptor α-mediated Control of Insulin-like Growth Factor (IGF) I Receptor Sensitivity to Ambient IGF, Leading to Phosphatidylinositol 3-Kinase/AKT-dependent Wnt/LRP5 Receptor-independent Activation of β-Catenin Signaling

Andrew Sunters, Victoria J. Armstrong, Gul Zaman, Robert M. Kypta, Yoshiaki Kawano, Lance E. Lanyon, Joanna S. Price

J Biol Chem. 2010 Mar 19; 285(12): 8743–8758. Published online 2009 Dec 30. doi: 10.1074/jbc.M109.027086

PMCID:: PMC2838297

Abstract Article PDF–4.2M

Select item 277970716.

Norrin, Frizzled4, and Lrp5 signaling in endothelial cells controls a genetic program for retinal vascularization

Xin Ye, Yanshu Wang, Hugh Cahill, Minzhong Yu, Tudor C. Badea, Philip M. Smallwood, Neal S. Peachey, Jeremy Nathans

Cell. Author manuscript; available in PMC 2010 Apr 16.

Published in final edited form as: Cell. 2009 Oct 16; 139(2): 285–298. doi: 10.1016/j.cell.2009.07.047

PMCID:: PMC2779707

Abstract Article PDF–5.3M

Select item 274317317.

LRP4 serves as a co-receptor of agrin

Bin Zhang, Shiwen Luo, Qiang Wang, Tatsuo Suzuki, Wen C. Xiong, Lin Mei

Neuron. Author manuscript; available in PMC 2009 Oct 23.

Published in final edited form as: Neuron. 2008 Oct 23; 60(2): 285–297. doi: 10.1016/j.neuron.2008.10.006

PMCID:: PMC2743173

Abstract Article PDF–1.8M

Select item 272045018.

The Wnt Receptor, Lrp5, Is Expressed by Mouse Mammary Stem Cells and Is Required to Maintain the Basal Lineage

Nisha M. Badders, Shruti Goel, Rod J. Clark, Kristine S. Klos, Soyoung Kim, Anna Bafico, Charlotta Lindvall, Bart O. Williams, Caroline M. Alexander

PLoS One. 2009; 4(8): e6594. Published online 2009 Aug 12. doi: 10.1371/journal.pone.0006594

PMCID:: PMC2720450

Abstract Article PDF–1.3M

Select item 270979619.

Interaction of the apolipoprotein E receptors low density lipoprotein receptorrelated protein and sorLA/LR11

Robert Spoelgen, Kenneth W. Adams, Mirjam Koker, Anne V. Thomas, Olav M. Andersen, Penelope J. Hallett, Kathryn K. Bercury, Daniel F. Joyner, Meihua Deng, William H. Stoothoff, Dudley K. Strickland, Thomas E. Willnow, Bradley T. Hyman

Neuroscience. Author manuscript; available in PMC 2010 Feb 18.

Published in final edited form as: Neuroscience. 2009 Feb 18; 158(4): 1460–1468. Published online 2008 Nov 8. doi: 10.1016/j.neuroscience.2008.10.061