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Select item 110787621.

Astrocytic β-catenin signaling via TCF7L2 regulates synapse development and social behavior

Lukasz Mateusz Szewczyk, Marcin Andrzej Lipiec, Ewa Liszewska, Ksenia Meyza, Joanna Urban-Ciecko, Ludwika Kondrakiewicz, Anna Goncerzewicz, Kamil Rafalko, Tomasz Grzegorz Krawczyk, Karolina Bogaj, Ilia Davidovich Vainchtein, Hiromi Nakao-Inoue, Alicja Puscian, Ewelina Knapska, Stephan J. Sanders, Tomasz Jan Nowakowski, Anna Victoria Molofsky, Marta Barbara Wisniewska

Mol Psychiatry. 2024; 29(1): 57–73. Published online 2023 Oct 5. doi: 10.1038/s41380-023-02281-y

PMCID:: PMC11078762

Abstract Article PDF–7.9M

Select item 109176602.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 108534533.

Dbx1 is a dorsal midbrain-specific determinant of GABAergic neuron fate and regulates differentiation of the dorsal midbrain into the inferior and superior colliculi

Hong-Nhung Tran, Quy-Hoai Nguyen, Yongsu Jeong

Front Cell Dev Biol. 2024; 12: 1336308. Published online 2024 Jan 26. doi: 10.3389/fcell.2024.1336308

PMCID:: PMC10853453

Abstract Article PDF–8.4M

Select item 102536674.

The Midbrain Preisthmus: A Poorly Known Effect of the Isthmic Organizer

Luis Puelles, Matias Hidalgo-Sánchez

Int J Mol Sci. 2023 Jun; 24(11): 9769. Published online 2023 Jun 5. doi: 10.3390/ijms24119769

PMCID:: PMC10253667

Abstract Article PDF–6.8M

Select item 102443745.

The embryonic patterning gene Dbx1 governs the survival of the auditory midbrain via Tcf7l2-Ap2δ transcriptional cascade

Hong-Nhung Tran, Quy-Hoai Nguyen, Ji-eun Jeong, Duc-Linh Loi, Youn Hee Nam, Tong Ho Kang, Jaeseung Yoon, Kwanghee Baek, Yongsu Jeong

Cell Death Differ. 2023 Jun; 30(6): 1563–1574. Published online 2023 Apr 20. doi: 10.1038/s41418-023-01165-6

PMCID:: PMC10244374

Abstract Article PDF–4.8M

Select item 102089756.

TCF7L2 acts as a molecular switch in midbrain to control mammal vocalization through its DNA binding domain but not transcription activation domain

Huihui Qi, Li Luo, Caijing Lu, Runze Chen, Xianyao Zhou, Xiaohui Zhang, Yichang Jia

Mol Psychiatry. 2023; 28(4): 1703–1717. Published online 2023 Feb 13. doi: 10.1038/s41380-023-01993-5

Correction in:: Mol Psychiatry. 2023; 28(4): 1718.

PMCID:: PMC10208975

Abstract Article PDF–3.4M

Select item 101087077.

Canonical Wnt signaling regulates soft palate development by mediating ciliary homeostasis

Eva Janečková, Jifan Feng, Tingwei Guo, Xia Han, Aileen Ghobadi, Angelita Araujo-Villalba, Md Shaifur Rahman, Heliya Ziaei, Thach-Vu Ho, Siddhika Pareek, Jasmine Alvarez, Yang Chai

Development. 2023 Mar 1; 150(5): dev201189. Published online 2023 Mar 9. doi: 10.1242/dev.201189

PMCID:: PMC10108707

Abstract Article

Select item 100362878.

Tcf7l2 in hepatocytes regulates de novo lipogenesis in diet-induced non-alcoholic fatty liver disease in mice

Da Som Lee, Tae Hyeon An, Hyunmi Kim, Eunsun Jung, Gyeonghun Kim, Seung Yeon Oh, Jun Seok Kim, Hye Jin Chun, Jaeeun Jung, Eun-Woo Lee, Baek-Soo Han, Dai Hoon Han, Yong-Ho Lee, Tae-Su Han, Keun Hur, Chul-Ho Lee, Dae-Soo Kim, Won Kon Kim, Jun Won Park, Seung-Hoi Koo, Je Kyung Seong, Sang Chul Lee, Hail Kim, Kwang-Hee Bae, Kyoung-Jin Oh

Diabetologia. 2023; 66(5): 931–954. Published online 2023 Feb 10. doi: 10.1007/s00125-023-05878-8

PMCID:: PMC10036287

Abstract Article PDF–13M

Select item 98513889.

Habenular Tcf7l2 links nicotine addiction to diabetes

Alexander Duncan, Mary P. Heyer, Masago Ishikawa, Stephanie P. B. Caligiuri, Xin-an Liu, Zuxin Chen, Maria Vittoria di Bonaventura, Karim Elayouby, Jessica L. Ables, William M. Howe, Purva Bali, Clementine Fillinger, Maya Williams, Richard O’Connor, Zichen Wang, Qun Lu, Theodore M. Kamenecka, Avi Ma’ayan, Heidi C. O’Neill, Ines Ibanez-Tallon, Aron M. Geurts, Paul J. Kenny

Nature. Author manuscript; available in PMC 2023 Jan 19.

Published in final edited form as: Nature. 2019 Oct; 574(7778): 372–377. Published online 2019 Oct 16. doi: 10.1038/s41586-019-1653-x

PMCID:: PMC9851388

Abstract Article PDF–2.1M

Select item 977207010.

TCF7l2, a nuclear marker that labels premyelinating oligodendrocytes and promotes oligodendroglial lineage progression

Fuzheng Guo, Yan Wang

Glia. Author manuscript; available in PMC 2023 Feb 1.

Published in final edited form as: Glia. 2023 Feb; 71(2): 143–154. Published online 2022 Jul 16. doi: 10.1002/glia.24249

PMCID:: PMC9772070

Abstract Article PDF–2.7M

Select item 972067211.

Dentate gyrus morphogenesis is regulated by β-catenin function in hem-derived fimbrial glia

Arpan Parichha, Debarpita Datta, Varun Suresh, Mallika Chatterjee, Michael J. Holtzman, Shubha Tole

Development. 2022 Nov 1; 149(21): dev200953. Published online 2022 Oct 23. doi: 10.1242/dev.200953

PMCID:: PMC9720672

Abstract Article

Select item 968719612.

FGF9 Promotes Expression of HAS2 in Palatal Elevation via the Wnt/β-Catenin/TCF7L2 Pathway

Yidan Sun, Xiyu Ying, Ruomei Li, Mengjia Weng, Jiajun Shi, Zhenqi Chen

Biomolecules. 2022 Nov; 12(11): 1639. Published online 2022 Nov 4. doi: 10.3390/biom12111639

PMCID:: PMC9687196

Abstract Article PDF–2.4M

Select item 962437413.

TCF7L2 transcriptionally regulates Fgf15 to maintain bile acid and lipid homeostasis through gut-liver crosstalk

Neha Bhat, Fatemehsadat Esteghamat, Bal Krishna Chaube, Kushan Gunawardhana, Mitra Mani, Clay Thames, Dhanpat Jain, Henry N. Ginsberg, Carlos Fernandes-Hernando, Arya Mani

FASEB J. Author manuscript; available in PMC 2023 Mar 1.

Published in final edited form as: FASEB J. 2022 Mar; 36(3): e22185. doi: 10.1096/fj.202101607R

Correction in:: FASEB J. 2022 Mar; 36(3): e22217.

PMCID:: PMC9624374

Abstract Article PDF–4.1M

Select item 948196914.

Integrated analysis of Wnt signalling system component gene expression

Paula Murphy, Chris Armit, Bill Hill, Shanmugasundaram Venkataraman, Patrick Frankel, Richard A. Baldock, Duncan R. Davidson

Development. 2022 Aug 15; 149(16): dev200312. Published online 2022 Aug 15. doi: 10.1242/dev.200312

PMCID:: PMC9481969

Abstract Article

Select item 933435315.

Aberrant androgen action in prostatic progenitor cells induces oncogenesis and tumor development through IGF1 and Wnt axes

Won Kyung Kim, Adam W. Olson, Jiaqi Mi, Jinhui Wang, Dong-Hoon Lee, Vien Le, Alex Hiroto, Joseph Aldahl, Christian H. Nenninger, Alyssa J. Buckley, Robert Cardiff, Sungyong You, Zijie Sun

Nat Commun. 2022; 13: 4364. Published online 2022 Jul 28. doi: 10.1038/s41467-022-32119-0

PMCID:: PMC9334353

Abstract Article PDF–13M

Select item 929827716.

Olanzapine Promotes the Occurrence of Metabolic Disorders in Conditional TCF7L2-Knockout Mice

Ye Yang, Manjun Shen, Li Li, Yujun Long, Lu Wang, Bing Lang, Renrong Wu

Front Cell Dev Biol. 2022; 10: 890472. Published online 2022 Jul 6. doi: 10.3389/fcell.2022.890472

PMCID:: PMC9298277

Abstract Article PDF–2.5M

Select item 929666617.

A brain precursor atlas reveals the acquisition of developmental-like states in adult cerebral tumours

Akram A. Hamed, Daniel J. Kunz, Ibrahim El-Hamamy, Quang M. Trinh, Omar D. Subedar, Laura M. Richards, Warren Foltz, Garrett Bullivant, Matthaeus Ware, Maria C. Vladoiu, Jiao Zhang, Antony M. Raj, Trevor J. Pugh, Michael D. Taylor, Sarah A. Teichmann, Lincoln D. Stein, Benjamin D. Simons, Peter B. Dirks

Nat Commun. 2022; 13: 4178. Published online 2022 Jul 19. doi: 10.1038/s41467-022-31408-y

PMCID:: PMC9296666

Abstract Article PDF–11M

Select item 922607518.

hnRNPH1 recruits PTBP2 and SRSF3 to modulate alternative splicing in germ cells

Shenglei Feng, Jinmei Li, Hui Wen, Kuan Liu, Yiqian Gui, Yujiao Wen, Xiaoli Wang, Shuiqiao Yuan

Nat Commun. 2022; 13: 3588. Published online 2022 Jun 23. doi: 10.1038/s41467-022-31364-7

PMCID:: PMC9226075

Abstract Article PDF–9.8M

Select item 916982519.

T-cell factor 7L2 is a novel regulator of osteoblast functions that acts in part by modulation of hypoxia signaling

Subburaman Mohan, Chandrasekhar Kesavan

Am J Physiol Endocrinol Metab. 2022 Jun 1; 322(6): E528–E539. Published online 2022 Apr 25. doi: 10.1152/ajpendo.00035.2022

PMCID:: PMC9169825

Abstract Article

Select item 878360920.

HOXA5 protein expression and genetic fate mapping show lineage restriction in the developing musculoskeletal system

Miriam A. Holzman, Jenna M. Bergmann, Maya Feldman, Kim Landry-Truchon, Lucie Jeannotte, Jennifer H. Mansfield

Int J Dev Biol. Author manuscript; available in PMC 2022 Jan 22.

Published in final edited form as: Int J Dev Biol. 2018; 62(11-12): 785–796. doi: 10.1387/ijdb.180214jm

PMCID:: PMC8783609

Abstract Article PDF–3.3M

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