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Items: 1 to 20 of 408

1.
Jag1/2 maintain esophageal homeostasis and suppress foregut tumorigenesis by restricting the basal progenitor cell pool
Haidi Huang, Yu Jiang, Jiangying Liu, Dan Luo, Jianghong Yuan, Rongzi Mu, Xiang Yu, Donglei Sun, Jihong Lin, Qiyue Chen, Xinjing Li, Ming Jiang, Jianming Xu, Bo Chu, Chengqian Yin, Lei Zhang, Youqiong Ye, Bo Cao, Qiong Wang, Yongchun Zhang
Nat Commun. 2024; 15: 4124. Published online 2024 May 15. doi: 10.1038/s41467-024-48347-5
PMCID:
PMC11096375
AbstractArticlePDF–9.5M
2.
Endothelial Jagged1 levels and distribution are post-transcriptionally controlled by ZFP36 decay proteins
Hannah L. Sunshine, Andrew C. Cicchetto, Karolina Elżbieta Kaczor-Urbanowicz, Feiyang Ma, Danielle Pi, Chloe Symons, Martin Turner, Vipul Shukla, Heather R. Christofk, Thomas A. Vallim, M. Luisa Iruela-Arispe
Cell Rep. Author manuscript; available in PMC 2024 Feb 23.
Published in final edited form as: Cell Rep. 2024 Jan 23; 43(1): 113627. Published online 2023 Dec 28. doi: 10.1016/j.celrep.2023.113627
PMCID:
PMC10884959
AbstractArticlePDF–4.0M
3.
Cis inhibition of NOTCH1 through JAGGED1 sustains embryonic hematopoietic stem cell fate
Roshana Thambyrajah, Maria Maqueda, Wen Hao Neo, Kathleen Imbach, Yolanda Guillén, Daniela Grases, Zaki Fadlullah, Stefano Gambera, Francesca Matteini, Xiaonan Wang, Fernando J. Calero-Nieto, Manel Esteller, Maria Carolina Florian, Eduard Porta, Rui Benedito, Berthold Göttgens, Georges Lacaud, Lluis Espinosa, Anna Bigas
Nat Commun. 2024; 15: 1604. Published online 2024 Feb 21. doi: 10.1038/s41467-024-45716-y
PMCID:
PMC10882055
AbstractArticlePDF–6.6M
4.
β-cell Jagged1 is sufficient but not necessary for islet Notch activity and insulin secretory defects in obese mice
Nina Suda, Alberto Bartolomé, Jiani Liang, Jinsook Son, Yoko Yagishita, Christian Siebel, Domenico Accili, Hongxu Ding, Utpal B. Pajvani
Mol Metab. 2024 Mar; 81: 101894. Published online 2024 Feb 3. doi: 10.1016/j.molmet.2024.101894
PMCID:
PMC10877406
AbstractArticlePDF–1.4M
5.
PIBF1 regulates trophoblast syncytialization and promotes cardiovascular development
Jong Geol Lee, Jung-Min Yon, Globinna Kim, Seul-Gi Lee, C-Yoon Kim, Seung-A Cheong, Hyun-Yi Kim, Jiyoung Yu, Kyunggon Kim, Young Hoon Sung, Hyun Ju Yoo, Dong-Cheol Woo, Jin Kyung Rho, Chang Hoon Ha, Chan-Gi Pack, Seak Hee Oh, Joon Seo Lim, Yu Mi Han, Eui-Ju Hong, Je Kyung Seong, Han-Woong Lee, Sang-Wook Lee, Ki-Up Lee, Chong Jai Kim, Sang-Yoon Nam, You Sook Cho, In-Jeoung Baek
Nat Commun. 2024; 15: 1487. Published online 2024 Feb 19. doi: 10.1038/s41467-024-45647-8
PMCID:
PMC10876648
AbstractArticlePDF–10M
6.
eNOS plays essential roles in the developing heart and aorta linked to disruption of Notch signalling
Lorraine Eley, Rachel V. Richardson, Ahlam Alqahtani, Bill Chaudhry, Deborah J. Henderson
Dis Model Mech. 2024 Jan 1; 17(1): dmm050265. Published online 2024 Jan 22. doi: 10.1242/dmm.050265
PMCID:
PMC10846539
AbstractArticle
7.
Jagged-1 Reduces Th2 Inflammation and Memory Cell Expansion in Allergic Airway Disease
Soichiro Kimura, Zadia Dupee, Felipe Lima, Ronald Allen, Soha Kazmi, Nickolas Diodati, Nicholas W. Lukacs, Steven L. Kunkel, Matthew Schaller
Immunohorizons. 2023 Feb 1; 7(2): 168–176. Published online 2023 Feb 2. doi: 10.4049/immunohorizons.2300001
PMCID:
PMC10563391
AbstractArticlePDF–1.6M
8.
Smarca4 deficiency induces Pttg1 oncogene upregulation and hyperproliferation of tubular and interstitial cells during kidney development
Jinshu Xu, Xianxiao Zhou, Ting Zhang, Bin Zhang, Pin-Xian Xu
Front Cell Dev Biol. 2023; 11: 1233317. Published online 2023 Sep 4. doi: 10.3389/fcell.2023.1233317
PMCID:
PMC10506413
AbstractArticlePDF–7.2M
9.
Innervation of the developing kidney in vivo and in vitro
Julia Tarnick, Mona Elhendawi, Ian Holland, Ziyuan Chang, Jamie A. Davies
Biol Open. 2023 Aug 15; 12(8): bio060001. Published online 2023 Jul 31. doi: 10.1242/bio.060001
PMCID:
PMC10411870
AbstractArticlePDF–5.7M
10.
Lrrn1 Regulates Medial Boundary Formation in the Developing Mouse Organ of Corti
Helen R. Maunsell, Kathryn Ellis, Matthew W. Kelley, Elizabeth Carroll Driver
J Neurosci. 2023 Jul 19; 43(29): 5305–5318. doi: 10.1523/JNEUROSCI.2141-22.2023
PMCID:
PMC10359035
AbstractArticlePDF–7.2M
11.
Molecular determinants of epithelial mesenchymal transition in mouse placenta and trophoblast stem cell
Shipra Kanti Jena, Shreya Das, Shreeta Chakraborty, Rupasri Ain
Sci Rep. 2023; 13: 10978. Published online 2023 Jul 6. doi: 10.1038/s41598-023-37977-2
PMCID:
PMC10325982
AbstractArticlePDF–7.1M
12.
Early radial positional information in the cochlea is optimized by a precise linear BMP gradient and enhanced by SOX2
Matthew J. Thompson, Caryl A. Young, Vidhya Munnamalai, David M. Umulis
Sci Rep. 2023; 13: 8567. Published online 2023 May 26. doi: 10.1038/s41598-023-34725-4
PMCID:
PMC10219982
AbstractArticlePDF–3.1M
13.
Notch1 and Notch4 core binding domain peptibodies exhibit distinct ligand-binding and anti-angiogenic properties
Timothy Sargis, Seock-Won Youn, Krishna Thakkar, L. A. Naiche, Na Yoon Paik, Kostandin V. Pajcini, Jan K. Kitajewski
Angiogenesis. 2023; 26(2): 249–263. Published online 2022 Nov 15. doi: 10.1007/s10456-022-09861-6
PMCID:
PMC10119233
AbstractArticlePDF–5.8M
14.
Tet2- and Tet3-Mediated Cytosine Hydroxymethylation in Six2 Progenitor Cells in Mice Is Critical for Nephron Progenitor Differentiation and Nephron Endowment
Xiujie Liang, Tamas Aranyi, Jianfu Zhou, Yuting Guan, Hailong Hu, Hongbo Liu, Katalin Susztak
J Am Soc Nephrol. 2023 Apr; 34(4): 572–589. Published online 2022 Dec 15. doi: 10.1681/ASN.2022040460
PMCID:
PMC10103262
AbstractArticle
15.
Notch Signaling Pathway in Tooth Shape Variations throughout Evolution
Thimios A. Mitsiadis, Pierfrancesco Pagella, Helder Gomes Rodrigues, Alexander Tsouknidas, Liza L. Ramenzoni, Freddy Radtke, Albert Mehl, Laurent Viriot
Cells. 2023 Mar; 12(5): 761. Published online 2023 Feb 27. doi: 10.3390/cells12050761
PMCID:
PMC10000876
AbstractArticlePDF–5.9M
16.
ZEB2 controls kidney stromal progenitor differentiation and inhibits abnormal myofibroblast expansion and kidney fibrosis
Sudhir Kumar, Xueping Fan, Hila Milo Rasouly, Richa Sharma, David J. Salant, Weining Lu
JCI Insight. 2023 Jan 10; 8(1): e158418. Published online 2023 Jan 10. doi: 10.1172/jci.insight.158418
PMCID:
PMC9870089
AbstractArticlePDF–8.1M
17.
Jag1-Notch cis-interaction determines cell fate segregation in pancreatic development
Xiaochan Xu, Philip Allan Seymour, Kim Sneppen, Ala Trusina, Anuska la Rosa Egeskov-Madsen, Mette Christine Jørgensen, Mogens Høgh Jensen, Palle Serup
Nat Commun. 2023; 14: 348. Published online 2023 Jan 21. doi: 10.1038/s41467-023-35963-w
PMCID:
PMC9867774
AbstractArticlePDF–4.4M
18.
Endocardium-to-coronary artery differentiation during heart development and regeneration involves sequential roles of Bmp2 and Cxcl12/Cxcr4
Gaetano D’Amato, Ragini Phansalkar, Jeffrey A. Naftaly, Xiaochen Fan, Zhainib A. Amir, Pamela E. Rios Coronado, Dale O. Cowley, Kelsey E. Quinn, Bikram Sharma, Kathleen M. Caron, Alessandra Vigilante, Kristy Red-Horse
Dev Cell. Author manuscript; available in PMC 2023 Nov 21.
Published in final edited form as: Dev Cell. 2022 Nov 21; 57(22): 2517–2532.e6. Published online 2022 Nov 7. doi: 10.1016/j.devcel.2022.10.007
PMCID:
PMC9833645
AbstractArticlePDF–3.0M
19.
PRDM16 expression and function in mammalian cochlear development
Michael Ebeid, Kathy Barnas, Hongji Zhang, Amal Yaghmour, Gabriele Noreikaite, Bryan C. Bjork
Dev Dyn. 2022 Oct; 251(10): 1666–1683. Published online 2022 May 7. doi: 10.1002/dvdy.480
PMCID:
PMC9790675
AbstractArticlePDF–17M
20.
Sex differences and risk factors for bleeding in Alagille syndrome
Simona Hankeova, Noemi Van Hul, Jakub Laznovsky, Elisabeth Verboven, Katrin Mangold, Naomi Hensens, Csaba Adori, Elvira Verhoef, Tomas Zikmund, Feven Dawit, Michaela Kavkova, Jakub Salplachta, Marika Sjöqvist, Bengt R Johansson, Mohamed G Hassan, Linda Fredriksson, Karsten Baumgärtel, Vitezslav Bryja, Urban Lendahl, Andrew Jheon, Florian Alten, Kristina Teär Fahnehjelm, Björn Fischler, Jozef Kaiser, Emma R Andersson
EMBO Mol Med. 2022 Dec; 14(12): e15809. Published online 2022 Nov 8. doi: 10.15252/emmm.202215809
PMCID:
PMC9728057
AbstractArticlePDF–12M

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