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Items: 1 to 20 of 246

1.
Beta2 adrenergic receptor–mediated abnormal myelopoiesis drives neuroinflammation in aged patients with traumatic brain injury
Rui Jiang, Zhichao Lu, Chenxing Wang, Jun Xiao, Qianqian Liu, Xide Xu, Jinlong Shi, Jianhong Shen, Xingjia Zhu, Peipei Gong, Qian-Xing Zhuang, Kaibin Shi, Wei Shi
Sci Adv. 2024 Jul 19; 10(29): eadp5239. Published online 2024 Jul 19. doi: 10.1126/sciadv.adp5239
PMCID:
PMC11259178
AbstractArticlePDF–8.6M
2.
Myeloid-derived suppressor cell mitochondrial fitness governs chemotherapeutic efficacy in hematologic malignancies
Saeed Daneshmandi, Jee Eun Choi, Qi Yan, Cameron R. MacDonald, Manu Pandey, Mounika Goruganthu, Nathan Roberts, Prashant K. Singh, Richard M. Higashi, Andrew N. Lane, Teresa W-M. Fan, Jianmin Wang, Philip L. McCarthy, Elizabeth A. Repasky, Hemn Mohammadpour
Nat Commun. 2024; 15: 2803. Published online 2024 Mar 30. doi: 10.1038/s41467-024-47096-9
PMCID:
PMC10981707
AbstractArticlePDF–3.0M
3.
Chronic stress promotes gastric cancer progression via the adrenoceptor beta 2/PlexinA1 pathway
Yanjie Lu, Die Cheng, Jiayu Pang, Yuqiao Peng, Shunkang Jin, Xinyu Zhang, Yuhong Li, Yanzhen Zuo
Cell Stress Chaperones. 2024 Feb; 29(1): 201–215. Published online 2024 Feb 6. doi: 10.1016/j.cstres.2024.02.001
PMCID:
PMC10939071
AbstractArticlePDF–12M
4.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
5.
Epinephrine inhibits PI3Kα via the Hippo kinases
Ting-Yu Lin, Shakti Ramsamooj, Tiffany Perrier, Katarina Liberatore, Louise Lantier, Neil Vasan, Kannan Karukurichi, Seo-Kyoung Hwang, Edward A. Kesicki, Edward R. Kastenhuber, Thorsten Wiederhold, Tomer M. Yaron, Emily M. Huntsman, Mengmeng Zhu, Yilun Ma, Marcia N. Paddock, Guoan Zhang, Benjamin D. Hopkins, Owen McGuinness, Robert E. Schwartz, Baran A. Ersoy, Lewis C. Cantley, Jared L. Johnson, Marcus D. Goncalves
Cell Rep. Author manuscript; available in PMC 2024 Jan 25.
Published in final edited form as: Cell Rep. 2023 Dec 26; 42(12): 113535. Published online 2023 Dec 4. doi: 10.1016/j.celrep.2023.113535
PMCID:
PMC10809223
AbstractArticlePDF–2.3M
6.
Identification and characterization of novel candidate compounds targeting 6- and 7-transmembrane μ-opioid receptor isoforms
Arjun Muralidharan, Alexander Samoshkin, Marino Convertino, Marjo Hannele Piltonen, Pavel Gris, Jian Wang, Changyu Jiang, Richard Klares, III, Alexander Linton, Ru-Rong Ji, William Maixner, Nikolay V. Dokholyan, Jeffrey S. Mogil, Luda Diatchenko
Br J Pharmacol. Author manuscript; available in PMC 2023 Dec 5.
Published in final edited form as: Br J Pharmacol. 2021 Jul; 178(13): 2709–2726. Published online 2021 Apr 30. doi: 10.1111/bph.15463
PMCID:
PMC10697213
AbstractArticlePDF–2.1M
7.
VMHdm/cSF-1 neuronal circuits regulate skeletal muscle PGC1-α via the sympathoadrenal drive
Takuya Yoshida, Mina Fujitani, Scotlynn Farmer, Ami Harada, Zhen Shi, Jenny J. Lee, Arely Tinajero, Ashish K. Singha, Teppei Fujikawa
Mol Metab. 2023 Nov; 77: 101792. Published online 2023 Aug 24. doi: 10.1016/j.molmet.2023.101792
PMCID:
PMC10491730
AbstractArticlePDF–2.6M
8.
Region-specific sympatho-adrenergic regulation of specialized vasculature in bone homeostasis and regeneration
Hao-Kun Xu, Jie-Xi Liu, Chen-Xi Zheng, Lu Liu, Chao Ma, Jiong-Yi Tian, Yuan Yuan, Yuan Cao, Shu-Juan Xing, Si-Ying Liu, Qiang Li, Ya-Juan Zhao, Liang Kong, Yong-Jin Chen, Bing-Dong Sui
iScience. 2023 Sep 15; 26(9): 107455. Published online 2023 Jul 22. doi: 10.1016/j.isci.2023.107455
PMCID:
PMC10481296
AbstractArticlePDF–7.8M
9.
GDF15 promotes weight loss by enhancing energy expenditure in muscle
Dongdong Wang, Logan K. Townsend, Geneviève J. DesOrmeaux, Sara M. Frangos, Battsetseg Batchuluun, Lauralyne Dumont, Rune Ehrenreich Kuhre, Elham Ahmadi, Sumei Hu, Irena A. Rebalka, Jaya Gautam, Maria Joy Therese Jabile, Chantal A. Pileggi, Sonia Rehal, Eric M. Desjardins, Evangelia E. Tsakiridis, James S. V. Lally, Emma Sara Juracic, A. Russell Tupling, Hertzel C. Gerstein, Guillaume Paré, Theodoros Tsakiridis, Mary-Ellen Harper, Thomas J. Hawke, John R. Speakman, Denis P. Blondin, Graham P. Holloway, Sebastian Beck Jørgensen, Gregory R. Steinberg
Nature. 2023; 619(7968): 143–150. Published online 2023 Jun 28. doi: 10.1038/s41586-023-06249-4
PMCID:
PMC10322716
AbstractArticlePDF–26M
10.
Neutrophil-derived catecholamines mediate negative stress effects on bone
Miriam E. A. Tschaffon-Müller, Elena Kempter, Lena Steppe, Sandra Kupfer, Melanie R. Kuhn, Florian Gebhard, Carlos Pankratz, Miriam Kalbitz, Konrad Schütze, Harald Gündel, Nele Kaleck, Gudrun Strauß, Jean Vacher, Hiroshi Ichinose, Katja Weimer, Anita Ignatius, Melanie Haffner-Luntzer, Stefan O. Reber
Nat Commun. 2023; 14: 3262. Published online 2023 Jun 5. doi: 10.1038/s41467-023-38616-0
PMCID:
PMC10241819
AbstractArticlePDF–3.1M
11.
Chronic stress promotes colorectal cancer progression by enhancing glycolysis through β2-AR/CREB1 signal pathway
Yunfeng Guan, Wang Yao, Hao Yu, Ying Feng, Yiyang Zhao, Xiangyang Zhan, Yan Wang
Int J Biol Sci. 2023; 19(7): 2006–2019. Published online 2023 Apr 2. doi: 10.7150/ijbs.79583
PMCID:
PMC10158030
AbstractArticlePDF–5.8M
12.
Occlusion preconditioned mice are resilient to hypobaric hypoxia-induced myocarditis and arrhythmias due to enhanced immunomodulation, metabolic homeostasis, and antioxidants defense
Gabriel Komla Adzika, Richard Mprah, Ruqayya Rizvi, Adebayo Oluwafemi Adekunle, Marie Louise Ndzie Noah, Prosperl Ivette Wowui, Seyram Yao Adzraku, Joseph Adu-Amankwaah, Fengli Wang, Yuwen Lin, Lu Fu, Xiaomei Liu, Jie Xiang, Hong Sun
Front Immunol. 2023; 14: 1124649. Published online 2023 Feb 15. doi: 10.3389/fimmu.2023.1124649
PMCID:
PMC9975755
AbstractArticlePDF–32M
13.
Catecholamine induces Kupffer cell apoptosis via growth differentiation factor 15 in alcohol-associated liver disease
Hee-Hoon Kim, Young-Ri Shim, Sung Eun Choi, Myung-Ho Kim, Giljae Lee, Hyun Ju You, Won-Mook Choi, Keungmo Yang, Tom Ryu, Kyurae Kim, Min Jeong Kim, Chaerin Woo, Katherine Po Sin Chung, Song Hwa Hong, Hyuk Soo Eun, Seok-Hwan Kim, GwangPyo Ko, Jong-Eun Park, Bin Gao, Won Kim, Won-Il Jeong
Exp Mol Med. 2023 Jan; 55(1): 158–170. Published online 2023 Jan 11. doi: 10.1038/s12276-022-00921-x
PMCID:
PMC9898237
AbstractArticlePDF–8.9M
14.
Activation of β2-Adrenergic Receptors in Microglia Alleviates Neuropathic Hypersensitivity in Mice
Elisa Damo, Amit Agarwal, Manuela Simonetti
Cells. 2023 Jan; 12(2): 284. Published online 2023 Jan 11. doi: 10.3390/cells12020284
PMCID:
PMC9856373
AbstractArticlePDF–9.2M
15.
Brain motor and fear circuits regulate leukocytes during acute stress
Wolfram C. Poller, Jeffrey Downey, Agnes A. Mooslechner, Nargis Khan, Long Li, Christopher T. Chan, Cameron S. McAlpine, Chunliang Xu, Florian Kahles, Shun He, Henrike Janssen, John E. Mindur, Sumnima Singh, Máté G. Kiss, Laura Alonso-Herranz, Yoshiko Iwamoto, Rainer H. Kohler, Lai Ping Wong, Kashish Chetal, Scott J. Russo, Ruslan I. Sadreyev, Ralph Weissleder, Matthias Nahrendorf, Paul S. Frenette, Maziar Divangahi, Filip K. Swirski
Nature. Author manuscript; available in PMC 2022 Dec 29.
Published in final edited form as: Nature. 2022 Jul; 607(7919): 578–584. Published online 2022 May 30. doi: 10.1038/s41586-022-04890-z
PMCID:
PMC9798885
AbstractArticlePDF–4.5M
16.
Noradrenergic signaling mediates cortical early tagging and storage of remote memory
Xiaocen Fan, Jiachen Song, Chaonan Ma, Yanbo Lv, Feifei Wang, Lan Ma, Xing Liu
Nat Commun. 2022; 13: 7623. Published online 2022 Dec 9. doi: 10.1038/s41467-022-35342-x
PMCID:
PMC9734098
AbstractArticlePDF–6.2M
17.
S-nitrosylation is required for β2AR desensitization and experimental asthma
Fabio V. Fonseca, Thomas M. Raffay, Kunhong Xiao, Precious J. McLaughlin, Zhaoxia Qian, Zachary W. Grimmett, Naoko Adachi, Benlian Wang, Alfred Hausladen, Brian A. Cobb, Rongli Zhang, Douglas T. Hess, Benjamin Gaston, Nevin A. Lambert, James D. Reynolds, Richard T. Premont, Jonathan S. Stamler
Mol Cell. Author manuscript; available in PMC 2023 Aug 18.
Published in final edited form as: Mol Cell. 2022 Aug 18; 82(16): 3089–3102.e7. Published online 2022 Aug 4. doi: 10.1016/j.molcel.2022.06.033
PMCID:
PMC9391322
AbstractArticlePDF–3.3M
18.
Adrenergic signaling controls early transcriptional programs during CD8+ T cell responses to viral infection
Leonardo D. Estrada, Didem Ağaç Çobanoğlu, Aaron Wise, Robert W. Maples, Murat Can Çobanoğlu, J. David Farrar
PLoS One. 2022; 17(8): e0272017. Published online 2022 Aug 9. doi: 10.1371/journal.pone.0272017
PMCID:
PMC9362915
AbstractArticlePDF–2.1M
19.
A functional circuit formed by the autonomic nerves and myofibroblasts controls mammalian alveolar formation for gas exchange
Kuan Zhang, Erica Yao, Shao-An Wang, Ethan Chuang, Julia Wong, Liliana Minichiello, Andrew Schroeder, Walter Eckalbar, Paul J. Wolters, Pao-Tien Chuang
Dev Cell. Author manuscript; available in PMC 2023 Jul 11.
Published in final edited form as: Dev Cell. 2022 Jul 11; 57(13): 1566–1581.e7. Published online 2022 Jun 16. doi: 10.1016/j.devcel.2022.05.021
PMCID:
PMC9308505
AbstractArticlePDF–5.9M
20.
Brown adipocyte ATF4 activation improves thermoregulation and systemic metabolism
Esther Paulo, Yun Zhang, Ruchi Masand, Tony L. Huynh, Youngho Seo, Danielle L. Swaney, Margaret Soucheray, Erica Stevenson, David Jimenez-Morales, Nevan J. Krogan, Biao Wang
Cell Rep. Author manuscript; available in PMC 2022 Jun 16.
Published in final edited form as: Cell Rep. 2021 Sep 21; 36(12): 109742. doi: 10.1016/j.celrep.2021.109742
PMCID:
PMC9202523
AbstractArticlePDF–4.2M

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