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Items: 1 to 20 of 31

1.
Mining cholesterol genes from thousands of mouse livers identifies aldolase C as a regulator of cholesterol biosynthesis
James A. Votava, Steven V. John, Zhonggang Li, Shuyang Chen, Jing Fan, Brian W. Parks
J Lipid Res. 2024 Mar; 65(3): 100525. Published online 2024 Feb 28. doi: 10.1016/j.jlr.2024.100525
PMCID:
PMC10965479
AbstractArticlePDF–2.3M
2.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
3.
Dysregulation of the Wnt/β-catenin signaling pathway via Rnf146 upregulation in a VPA-induced mouse model of autism spectrum disorder
Gaeun Park, Wooyoung Eric Jang, Seoyeon Kim, Edson Luck Gonzales, Jungeun Ji, Seunghwan Choi, Yujin Kim, Ji Hwan Park, Hazara Begum Mohammad, Geul Bang, Minkyung Kang, Soobin Kim, Se Jin Jeon, Jin Young Kim, Kwang Pyo Kim, Chan Young Shin, Joon-Yong An, Min-Sik Kim, Yong-Seok Lee
Exp Mol Med. 2023 Aug; 55(8): 1783–1794. Published online 2023 Aug 1. doi: 10.1038/s12276-023-01065-2
PMCID:
PMC10474298
AbstractArticlePDF–4.0M
4.
ECHDC1 knockout mice accumulate ethyl-branched lipids and excrete abnormal intermediates of branched-chain fatty acid metabolism
Joseph P. Dewulf, Stéphanie Paquay, Etienne Marbaix, Younès Achouri, Emile Van Schaftingen, Guido T. Bommer
J Biol Chem. 2021 Oct; 297(4): 101083. Published online 2021 Aug 19. doi: 10.1016/j.jbc.2021.101083
PMCID:
PMC8473548
AbstractArticlePDF–1.6M
5.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
6.
Telencephalic Embryonic Subtractive Sequences: A Unique Collection of Neurodevelopmental Genes
Alessandro Bulfone, Pietro Carotenuto, Andrea Faedo, Veruska Aglio, Livia Garzia, Anna Maria Bello, Andrea Basile, Alessandra Andrè, Massimo Cocchia, Ombretta Guardiola, Andrea Ballabio, John L. R. Rubenstein, Massimo Zollo
J Neurosci. 2005 Aug 17; 25(33): 7586–7600. doi: 10.1523/JNEUROSCI.0522-05.2005
PMCID:
PMC6725394
AbstractArticlePDF–682K
7.
New roles for the de-ubiquitylating enzyme OTUD4 in an RNA–protein network and RNA granules
Richa Das, Lukas Schwintzer, Stanislav Vinopal, Eva Aguado Roca, Marc Sylvester, Ana-Maria Oprisoreanu, Susanne Schoch, Frank Bradke, Meike Broemer
J Cell Sci. 2019 Jun 15; 132(12): jcs229252. Published online 2019 Jun 17. doi: 10.1242/jcs.229252
PMCID:
PMC6602300
AbstractArticle
8.
Rhododendrin-Induced RNF146 Expression via Estrogen Receptor β Activation is Cytoprotective Against 6-OHDA-Induced Oxidative Stress
Hyojung Kim, Jisoo Park, HyunHee Leem, MyoungLae Cho, Jin-Ha Yoon, Han-Joo Maeng, Yunjong Lee
Int J Mol Sci. 2019 Apr; 20(7): 1772. Published online 2019 Apr 10. doi: 10.3390/ijms20071772
PMCID:
PMC6479468
AbstractArticlePDF–4.8M
9.
An FBXW7-ZEB2 axis links EMT and tumour microenvironment to promote colorectal cancer stem cells and chemoresistance
Ningning Li, Roya Babaei-Jadidi, Federica Lorenzi, Bradley Spencer-Dene, Philip Clarke, Enric Domingo, Eugene Tulchinsky, Robert G. J. Vries, David Kerr, Yihang Pan, Yulong He, David O. Bates, Ian Tomlinson, Hans Clevers, Abdolrahman S. Nateri
Oncogenesis. 2019 Mar; 8(3): 13. Published online 2019 Feb 19. doi: 10.1038/s41389-019-0125-3
PMCID:
PMC6381143
AbstractArticlePDF–10M
10.
Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors
Hyeonwoo Kim, Christiane D. Wrann, Mark Jedrychowski, Sara Vidoni, Yukiko Kitase, Kenichi Nagano, Chenhe Zhou, Joshua Chou, Virginia-Jeni A. Parkman, Scott J. Novick, Timothy S. Strutzenberg, Bruce D. Pascal, Phuong T. Le, Daniel J. Brooks, Alexander M. Roche, Kaitlyn K. Gerber, Laura Mattheis, Wenjing Chen, Hua Tu, Mary L. Bouxsein, Patrick R. Griffin, Roland Baron, Clifford J. Rosen, Lynda F. Bonewald, Bruce M. Spiegelman
Cell. Author manuscript; available in PMC 2019 Dec 13.
Published in final edited form as: Cell. 2018 Dec 13; 175(7): 1756–1768.e17. doi: 10.1016/j.cell.2018.10.025
Correction in:
Cell. 2019 Jul 11; 178(2): 507–508.
PMCID:
PMC6298040
AbstractArticlePDF–1.2M
11.
Ubiquitin ligase RNF146 coordinates bone dynamics and energy metabolism
Yoshinori Matsumoto, Jose La Rose, Melissa Lim, Hibret A. Adissu, Napoleon Law, Xiaohong Mao, Feng Cong, Paula Mera, Gerard Karsenty, David Goltzman, Adele Changoor, Lucia Zhang, Megan Stajkowski, Marc D. Grynpas, Carsten Bergmann, Robert Rottapel
J Clin Invest. 2017 Jun 30; 127(7): 2612–2625. Published online 2017 Jun 5. doi: 10.1172/JCI92233
PMCID:
PMC5490759
AbstractArticlePDF–5.2M
12.
RANKL coordinates multiple osteoclastogenic pathways by regulating expression of ubiquitin ligase RNF146
Yoshinori Matsumoto, Jose Larose, Oliver A. Kent, Melissa Lim, Adele Changoor, Lucia Zhang, Yaryna Storozhuk, Xiaohong Mao, Marc D. Grynpas, Feng Cong, Robert Rottapel
J Clin Invest. 2017 Apr 3; 127(4): 1303–1315. Published online 2017 Mar 13. doi: 10.1172/JCI90527
PMCID:
PMC5373870
AbstractArticlePDF–3.6M
13.
Allosteric Activation of the RNF146 Ubiquitin Ligase by a Poly(ADP-ribosyl)ation Signal
Paul A. DaRosa, Zhizhi Wang, Xiaomo Jiang, Jonathan N. Pruneda, Feng Cong, Rachel E. Klevit, Wenqing Xu
Nature. Author manuscript; available in PMC 2015 Jul 8.
Published in final edited form as: Nature. 2015 Jan 8; 517(7533): 223–226. Published online 2014 Oct 19. doi: 10.1038/nature13826
PMCID:
PMC4289021
AbstractArticlePDF–4.0M
14.
Modulation of Poly(ADP-Ribose) Polymerase-1 (PARP-1)-Mediated Oxidative Cell Injury by Ring Finger Protein 146 (RNF146) in Cardiac Myocytes
Domokos Gerö, Petra Szoleczky, Athanasia Chatzianastasiou, Andreas Papapetropoulos, Csaba Szabo
Mol Med. 2014; 20(1): 313–328. Prepublished online 2014 May 14. Published online 2014 Jul 31. doi: 10.2119/molmed.2014.00102
PMCID:
PMC4153837
AbstractArticlePDF–29M
15.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
16.
A Genome-Wide Screen to Identify Transcription Factors Expressed in Pelvic Ganglia of the Lower Urinary Tract
Carrie B. Wiese, Sara Ireland, Nicole L. Fleming, Jing Yu, M. Todd Valerius, Kylie Georgas, Han Sheng Chiu, Jane Brennan, Jane Armstrong, Melissa H. Little, Andrew P. McMahon, E. Michelle Southard-Smith
Front Neurosci. 2012; 6: 130. Published online 2012 Sep 12. doi: 10.3389/fnins.2012.00130
PMCID:
PMC3439845
AbstractArticlePDF–1.4M
17.
Global Gene Expression Analysis of Murine Limb Development
Leila Taher, Nicole M. Collette, Deepa Murugesh, Evan Maxwell, Ivan Ovcharenko, Gabriela G. Loots
PLoS One. 2011; 6(12): e28358. Published online 2011 Dec 9. doi: 10.1371/journal.pone.0028358
PMCID:
PMC3235105
AbstractArticlePDF–4.5M
18.
Ethylmalonyl-CoA Decarboxylase, a New Enzyme Involved in Metabolite Proofreading
Carole L. Linster, Gaëtane Noël, Vincent Stroobant, Didier Vertommen, Marie-Françoise Vincent, Guido T. Bommer, Maria Veiga-da-Cunha, Emile Van Schaftingen
J Biol Chem. 2011 Dec 16; 286(50): 42992–43003. Published online 2011 Oct 20. doi: 10.1074/jbc.M111.281527
PMCID:
PMC3234807
AbstractArticlePDF–2.5M
19.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
20.
Iduna is a poly(ADP-ribose) (PAR)-dependent E3 ubiquitin ligase that regulates DNA damage
Ho Chul Kang, Yun-Il Lee, Joo-Ho Shin, Shaida A. Andrabi, Zhikai Chi, Jean-Philippe Gagné, Yunjong Lee, Han Seok Ko, Byoung Dae Lee, Guy G. Poirier, Valina L. Dawson, Ted M. Dawson
Proc Natl Acad Sci U S A. 2011 Aug 23; 108(34): 14103-14108. Published online 2011 Aug 8. doi: 10.1073/pnas.1108799108
PMCID:
PMC3161609
AbstractArticlePDF–1.5M

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