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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 79387702.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 76869153.

Twinfilin bypasses assembly conditions and actin filament aging to drive barbed end depolymerization

Shashank Shekhar, Gregory J. Hoeprich, Jeff Gelles, Bruce L. Goode

J Cell Biol. 2021 Jan 4; 220(1): e202006022. Published online 2020 Nov 23. doi: 10.1083/jcb.202006022

PMCID:: PMC7686915

Abstract Article PDF–2.7M

Select item 72525394.

Actin/microtubule crosstalk during platelet biogenesis in mice is critically regulated by Twinfilin1 and Cofilin1

Isabelle C. Becker, Inga Scheller, Lou M. Wackerbarth, Sarah Beck, Tobias Heib, Katja Aurbach, Georgi Manukjan, Carina Gross, Markus Spindler, Zoltan Nagy, Walter Witke, Pekka Lappalainen, Markus Bender, Harald Schulze, Irina Pleines, Bernhard Nieswandt

Blood Adv. 2020 May 26; 4(10): 2124–2134. Published online 2020 May 14. doi: 10.1182/bloodadvances.2019001303

PMCID:: PMC7252539

Abstract Article PDF–2.0M

Select item 64595105.

Mouse screen reveals multiple new genes underlying mouse and human hearing loss

Neil J. Ingham, Selina A. Pearson, Valerie E. Vancollie, Victoria Rook, Morag A. Lewis, Jing Chen, Annalisa Buniello, Elisa Martelletti, Lorenzo Preite, Chi Chung Lam, Felix D. Weiss, Zӧe Powis, Pim Suwannarat, Christopher J. Lelliott, Sally J. Dawson, Jacqueline K. White, Karen P. Steel

PLoS Biol. 2019 Apr; 17(4): e3000194. Published online 2019 Apr 11. doi: 10.1371/journal.pbio.3000194

PMCID:: PMC6459510

Abstract Article PDF–5.1M

Select item 63334606.

ATG5 is required for B cell polarization and presentation of particulate antigens

Florent Arbogast, Johan Arnold, Philippe Hammann, Lauriane Kuhn, Johana Chicher, Diane Murera, Justine Weishaar, Sylviane Muller, Jean-Daniel Fauny, Frédéric Gros

Autophagy. 2019; 15(2): 280–294. Published online 2018 Sep 22. doi: 10.1080/15548627.2018.1516327

PMCID:: PMC6333460

Abstract Article PDF–2.7M

Select item 62627777.

LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow

Hui-yuan Tseng, Anna V. Samarelli, Patricia Kammerer, Sarah Scholze, Tilman Ziegler, Roland Immler, Roy Zent, Markus Sperandio, Charles R. Sanders, Reinhard Fässler, Ralph T. Böttcher

J Cell Sci. 2018 Nov 15; 131(22): jcs218214. Published online 2018 Nov 21. doi: 10.1242/jcs.218214

PMCID:: PMC6262777

Abstract Article

Select item 62490028.

A novel mode of capping protein-regulation by twinfilin

Adam B Johnston, Denise M Hilton, Patrick McConnell, Britney Johnson, Meghan T Harris, Avital Simone, Gaya K Amarasinghe, John A Cooper, Bruce L Goode

eLife. 2018; 7: e41313. Published online 2018 Oct 23. doi: 10.7554/eLife.41313

PMCID:: PMC6249002

Abstract Article PDF–5.4M

Select item 62441839.

Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells

Sunyuan Zhang, Nicholas A. Williamson, Marie A. Bogoyevitch

Sci Data. 2018; 5: 180262. Published online 2018 Nov 20. doi: 10.1038/sdata.2018.262

PMCID:: PMC6244183

Abstract Article PDF–753K

Select item 588012210.

Molecular mechanism for inhibition of twinfilin by phosphoinositides

Markku Hakala, Maria Kalimeri, Giray Enkavi, Ilpo Vattulainen, Pekka Lappalainen

J Biol Chem. 2018 Mar 30; 293(13): 4818–4829. Published online 2018 Feb 7. doi: 10.1074/jbc.RA117.000484

PMCID:: PMC5880122

Abstract Article PDF–1.5M

Select item 564508211.

Spatio-temporal profile of postynaptic interactomes integrates components of complex brain disorders

Jing Li, Wangshu Zhang, Hui Yang, Daniel P. Howrigan, Brent Wilkinson, Tade Souaiaia, Oleg V. Evgrafov, Giulio Genovese, Veronica A. Clementel, Jennifer C. Tudor, Ted Abel, James A. Knowles, Benjamin M. Neale, Kai Wang, Fengzhu Sun, Marcelo P. Coba

Nat Neurosci. Author manuscript; available in PMC 2018 Aug 1.

Published in final edited form as: Nat Neurosci. 2017 Aug; 20(8): 1150–1161. Published online 2017 Jun 26. doi: 10.1038/nn.4594

PMCID:: PMC5645082

Abstract Article PDF–2.3M

Select item 433099912.

Spontaneous development of hepatocellular carcinoma with cancer stem cell properties in PR-SET7-deficient livers

Kostas C Nikolaou, Panagiotis Moulos, George Chalepakis, Pantelis Hatzis, Hisanobu Oda, Danny Reinberg, Iannis Talianidis

EMBO J. 2015 Feb 12; 34(4): 430–447. Published online 2014 Dec 16. doi: 10.15252/embj.201489279

PMCID:: PMC4330999

Abstract Article PDF–4.8M

Select item 399589413.

Fibroblast Growth Factor signaling regulates the expansion of A6-expressing hepatocytes in association with AKT-dependent β-catenin activation

Sarah Utley, David James, Nirmala Mavila, Marie V. Nguyen, Christopher Vendryes, S. Michael Salisbury, Jennifer Phan, Kasper S. Wang

J Hepatol. Author manuscript; available in PMC 2015 May 1.

Published in final edited form as: J Hepatol. 2014 May; 60(5): 1002–1009. Published online 2013 Dec 21. doi: 10.1016/j.jhep.2013.12.017

PMCID:: PMC3995894

Abstract Article PDF–2.2M

Select item 374561014.

Molecular Characterization of Mutant Mouse Strains Generated from the EUCOMM/KOMP-CSD ES Cell Resource

Edward Ryder, Diane Gleeson, Debarati Sethi, Sapna Vyas, Evelina Miklejewska, Priya Dalvi, Bishoy Habib, Ross Cook, Matthew Hardy, Kalpesh Jhaveri, Joanna Bottomley, Hannah Wardle-Jones, James N. Bussell, Richard Houghton, Jennifer Salisbury, William C. Skarnes, Sanger Mouse Genetics Project, Ramiro Ramirez-Solis

Mamm Genome. 2013; 24(7): 286–294. Published online 2013 Aug 4. doi: 10.1007/s00335-013-9467-x

PMCID:: PMC3745610

Abstract Article PDF–353K

Select item 357241015.

A conditional knockout resource for the genome–wide study of mouse gene function

William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley

Nature. Author manuscript; available in PMC 2013 Feb 14.

Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163

PMCID:: PMC3572410

Abstract Article PDF–1.1M

Select item 317805916.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 312173517.

Deterministic and Stochastic Allele Specific Gene Expression in Single Mouse Blastomeres

Fuchou Tang, Catalin Barbacioru, Ellen Nordman, Siqin Bao, Caroline Lee, Xiaohui Wang, Brian B. Tuch, Edith Heard, Kaiqin Lao, M. Azim Surani

PLoS One. 2011; 6(6): e21208. Published online 2011 Jun 23. doi: 10.1371/journal.pone.0021208

PMCID:: PMC3121735

Abstract Article PDF–1.0M

Select item 302253418.

A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo

Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio

PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582

PMCID:: PMC3022534

Abstract Article PDF–3.8M

Select item 244789519.

Structure of the actin-depolymerizing factor homology domain in complex with actin

Ville O. Paavilainen, Esko Oksanen, Adrian Goldman, Pekka Lappalainen

J Cell Biol. 2008 Jul 14; 182(1): 51–59. doi: 10.1083/jcb.200803100

PMCID:: PMC2447895

Abstract Article PDF–3.0M

Select item 219883120.

Interactions with PIP₂, ADP-actin monomers, and capping protein regulate the activity and localization of yeast twinfilin

Sandra Palmgren, Pauli J. Ojala, Martin A. Wear, John A. Cooper, Pekka Lappalainen

J Cell Biol. 2001 Oct 15; 155(2): 251–260. doi: 10.1083/jcb.200106157

PMCID:: PMC2198831

Abstract Article PDF–204K

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