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Items: 1 to 20 of 136

1.
MST1 knockdown inhibits osteoarthritis progression through Parkin‐mediated mitophagy and Nrf2/NF‐κB signalling pathway
Hantao Ye, Tingwen Cai, Yang Shen, Lin Zhao, Haojie Zhang, Jianxin Yang, Feida Li, Jiaoxiang Chen, Xiaolong Shui
J Cell Mol Med. 2024 Jun; 28(11): e18476. Published online 2024 Jun 6. doi: 10.1111/jcmm.18476
PMCID:
PMC11154837
AbstractArticlePDF–31M
2.
The Mst1/2-BNIP3 axis is required for mitophagy induction and neuronal viability under mitochondrial stress
Dae Jin Jeong, Jee-Hyun Um, Young Yeon Kim, Dong Jin Shin, Sangwoo Im, Kang-Min Lee, Yun-Hee Lee, Dae-sik Lim, Donghoon Kim, Jeanho Yun
Exp Mol Med. 2024 Mar; 56(3): 674–685. Published online 2024 Mar 5. doi: 10.1038/s12276-024-01198-y
PMCID:
PMC10984967
AbstractArticlePDF–4.8M
3.
Smurf1 polyubiquitinates on K285/K282 of the kinases Mst1/2 to attenuate their tumor-suppressor functions
Yana Xu, Meiyu Qu, Yangxun He, Qiangqiang He, Tingyu Shen, Jiahao Luo, Dan Tan, Hangyang Bao, Chengyun Xu, Xing Ji, Xinhua Hu, Muhammad Qasim Barkat, Ling-Hui Zeng, Ximei Wu
J Biol Chem. 2023 Dec; 299(12): 105395. Published online 2023 Oct 27. doi: 10.1016/j.jbc.2023.105395
PMCID:
PMC10696403
AbstractArticlePDF–5.4M
4.
STK4 is a prognostic biomarker correlated with immune infiltrates in clear cell renal cell carcinoma
Zi-Yuan Bai, Lu-Shan Peng, Run-Qi Li, Xianchu Peng, Zhe Yang
Aging (Albany NY) 2023 Oct 31; 15(20): 11286–11297. Published online 2023 Oct 20. doi: 10.18632/aging.205127
PMCID:
PMC10637789
AbstractArticlePDF–1.6M
5.
Mapping the MOB proteins’ proximity network reveals a unique interaction between human MOB3C and the RNase P complex
Islam E. Elkholi, Jonathan Boulais, Marie-Pier Thibault, Hong-Duc Phan, Amélie Robert, Lien B. Lai, Denis Faubert, Matthew J. Smith, Venkat Gopalan, Jean-Franҫois Côté
J Biol Chem. 2023 Sep; 299(9): 105123. Published online 2023 Aug 1. doi: 10.1016/j.jbc.2023.105123
PMCID:
PMC10480535
AbstractArticlePDF–2.4M
6.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M
7.
Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity
Martin Golkowski, Andrea Lius, Tanmay Sapre, Ho-Tak Lau, Taylor Moreno, Dustin J. Maly, Shao-En Ong
Mol Cell. Author manuscript; available in PMC 2023 Apr 4.
Published in final edited form as: Mol Cell. 2023 Mar 2; 83(5): 803–818.e8. Published online 2023 Feb 2. doi: 10.1016/j.molcel.2023.01.015
PMCID:
PMC10072906
AbstractArticlePDF–4.2M
8.
CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment
Daphne J. Smits, Jordy Dekker, Rachel Schot, Brahim Tabarki, Amal Alhashem, Jeroen A. A. Demmers, Dick H. W. Dekkers, Antonio Romito, Peter J. van der Spek, Tjakko J. van Ham, Aida M. Bertoli-Avella, Grazia M. S. Mancini
Hum Genet. 2023; 142(3): 379–397. Published online 2022 Dec 20. doi: 10.1007/s00439-022-02511-3
PMCID:
PMC9950183
AbstractArticlePDF–2.4M
9.
LncRNA GAS5 enhances tumor stem cell-like medicated sensitivity of paclitaxel and inhibits epithelial-to-mesenchymal transition by targeting the miR-18a-5p/STK4 pathway in prostate cancer
Ting-Ting Lu, Xia Tao, Hua-Lei Li, Ling Gai, Hua Huang, Feng Li
Asian J Androl. 2022 Nov-Dec; 24(6): 643–652. Published online 2022 Mar 15. doi: 10.4103/aja2021117
PMCID:
PMC9809493
AbstractArticlePDF–3.2M
10.
A whole genome CRISPR screen identifies AHR loss as a mechanism of resistance to a PARP7 inhibitor
Huadong Chen, Morgan E. Diolaiti, Patrick C. O’Leary, Ajda Rojc, Nevan J. Krogan, Minkyu Kim, Alan Ashworth
Mol Cancer Ther. Author manuscript; available in PMC 2023 Jan 5.
Published in final edited form as: Mol Cancer Ther. 2022 Jul 5; 21(7): 1076–1089. doi: 10.1158/1535-7163.MCT-21-0841
PMCID:
PMC9769698
AbstractArticlePDF–2.7M
11.
Crosstalk between the Hippo Pathway and the Wnt Pathway in Huntington’s Disease and Other Neurodegenerative Disorders
Pasquale Sileo, Clémence Simonin, Patricia Melnyk, Marie-Christine Chartier-Harlin, Philippe Cotelle
Cells. 2022 Nov; 11(22): 3631. Published online 2022 Nov 16. doi: 10.3390/cells11223631
PMCID:
PMC9688160
AbstractArticlePDF–1.8M
12.
Deficiency of MST1 in endometriosis related peritoneal macrophages promoted the autophagy of ectopic endometrial stromal cells by IL-10
Yufei Huang, Shumin Yan, Xiaoyu Dong, Xue Jiao, Shuang Wang, Dong Li, Guoyun Wang
Front Immunol. 2022; 13: 993788. Published online 2022 Oct 3. doi: 10.3389/fimmu.2022.993788
PMCID:
PMC9575673
AbstractArticlePDF–10M
13.
Regulation of MST complexes and activity via SARAH domain modifications
Sofiia Karchugina, Dorothy Benton, Jonathan Chernoff
Biochem Soc Trans. Author manuscript; available in PMC 2022 Oct 7.
Published in final edited form as: Biochem Soc Trans. 2021 Apr 30; 49(2): 675–683. doi: 10.1042/BST20200559
PMCID:
PMC9540434
AbstractArticlePDF–485K
14.
ALS-linked loss of Cyclin-F function affects HSP90
Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends
Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359
PMCID:
PMC9481933
AbstractArticlePDF–3.5M
15.
Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery
Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili
Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z
PMCID:
PMC9279285
AbstractArticlePDF–2.5M
16.
OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization
Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti
Science. Author manuscript; available in PMC 2022 Sep 11.
Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983
PMCID:
PMC9119736
AbstractArticlePDF–3.3M
17.
The involvement of Parkin-dependent mitophagy in the anti-cancer activity of Ginsenoside
Xin Sun, Yeting Hong, Yuhan Shu, Caixia Wu, Guiqin Ye, Hanxiao Chen, Hongying Zhou, Ruilan Gao, Jianbin Zhang
J Ginseng Res. 2022 Mar; 46(2): 266–274. Published online 2021 Jul 8. doi: 10.1016/j.jgr.2021.06.009
PMCID:
PMC9058836
AbstractArticlePDF–2.9M
18.
The Hippo pathway kinases LATS1 and 2 attenuate cellular responses to heavy metals through phosphorylating MTF1
Han Han, Hiroki J Nakaoka, Line Hofmann, Jeff Jiajing Zhou, Clinton Yu, Lisha Zeng, Junyu Nan, Gayoung Seo, Rebecca Elizabeth Vargas, Bing Yang, Ruxi Qi, Lee Bardwell, Dmitry A. Fishman, Ken W.Y. Cho, Lan Huang, Ray Luo, Rahul Warrior, Wenqi Wang
Nat Cell Biol. Author manuscript; available in PMC 2022 Jul 13.
Published in final edited form as: Nat Cell Biol. 2022 Jan; 24(1): 74–87. Published online 2022 Jan 13. doi: 10.1038/s41556-021-00813-8
PMCID:
PMC9022944
AbstractArticlePDF–8.9M
19.
Circular RNA_0057209 Acts as ceRNA to Inhibit Thyroid Cancer Progression by Promoting the STK4-Mediated Hippo Pathway via Sponging MicroRNA-183
Xinzhi Peng, Yue Zhu, Shaojian Lin, Weiming Yu, Cheng Zhang, Langping Tan, Miaoyun Long, Dingyuan Luo, Chengcheng Ji
Oxid Med Cell Longev. 2022; 2022: 9974639. Published online 2022 Mar 11. doi: 10.1155/2022/9974639
PMCID:
PMC8933075
AbstractArticlePDF–3.1M
20.
Histone deacetylase inhibitors inhibit cervical cancer growth through Parkin acetylation-mediated mitophagy
Xin Sun, Yuhan Shu, Guiqin Ye, Caixia Wu, Mengting Xu, Ruilan Gao, Dongsheng Huang, Jianbin Zhang
Acta Pharm Sin B. 2022 Feb; 12(2): 838–852. Published online 2021 Jul 21. doi: 10.1016/j.apsb.2021.07.003
PMCID:
PMC8897022
AbstractArticlePDF–3.0M

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