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Select item 96885971.

LTB4R Promotes the Occurrence and Progression of Clear Cell Renal Cell Carcinoma (ccRCC) by Regulating the AKT/mTOR Signaling Pathway

Xiao Zhang, Huahui Wu, Xin Yan, Jiajun Ma, Zhao Chen

Cells. 2022 Nov; 11(22): 3606. Published online 2022 Nov 15. doi: 10.3390/cells11223606

PMCID:: PMC9688597

Abstract Article PDF–6.6M

Select item 90109812.

白三烯B4受体在急性髓系白血病中的预后价值和功能富集分析

张晓宁, 张晓瑜, 刘鹏, 刘阔, 李文文, 陈倩倩, 马万山

Nan Fang Yi Ke Da Xue Xue Bao. 2022 Mar 20; 42(3): 309–320. Chinese. doi: 10.12122/j.issn.1673-4254.2022.03.01

PMCID:: PMC9010981

Abstract Article PDF–6.0M

Select item 85692143.

Leukotriene B4 receptor-2 contributes to KRAS-driven lung tumor formation by promoting interleukin-6-mediated inflammation

Jae-Hyun Jang, Donghwan Park, Guen-soo Park, Dong-Wook Kwak, JaeIn Park, Dae-Yeul Yu, Hye Jin You, Jae-Hong Kim

Exp Mol Med. 2021 Oct; 53(10): 1559–1568. Published online 2021 Oct 11. doi: 10.1038/s12276-021-00682-z

PMCID:: PMC8569214

Abstract Article PDF–4.1M

Select item 66800884.

DNA methylation and inflammation marker profiles associated with a history of depression

Bethany Crawford, Zoe Craig, Georgina Mansell, Isobel White, Adam Smith, Steve Spaull, Jennifer Imm, Eilis Hannon, Andrew Wood, Hanieh Yaghootkar, Yingjie Ji, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Niamh Mullins, Cathryn M Lewis, Jonathan Mill, Therese M Murphy

Hum Mol Genet. 2018 Aug 15; 27(16): 2840–2850. Published online 2018 May 22. doi: 10.1093/hmg/ddy199

PMCID:: PMC6680088

Abstract Article PDF–690K

Select item 61308345.

BLT2, a leukotriene B₄ receptor 2, as a novel prognostic biomarker of triple-negative breast cancer

JaeIn Park, Jae-Hyun Jang, Geun-Soo Park, Yunro Chung, Hye Jin You, Jae-Hong Kim

BMB Rep. 2018 Aug; 51(8): 373–377. Published online 2018 Aug 31. doi: 10.5483/BMBRep.2018.51.8.127

PMCID:: PMC6130834

Abstract Article PDF–1.1M

Select item 57758896.

Supernatants and Lipids from Stored RBCs Activate Pulmonary Microvascular Endothelium through the BLT2 Receptor and Protein Kinase C Activation

Christopher C. Silliman, Marguerite R. Kelher, Samina Y. Khan, F. Bernadette West, Nathan J. D. McLaughlin, David J. Elzi, Kelly J. England, Jason Bjornsen, Susan A. Kuldanek, Anirban Banerjee

Transfusion. Author manuscript; available in PMC 2018 Nov 1.

Published in final edited form as: Transfusion. 2017 Nov; 57(11): 2690–2700. Published online 2017 Sep 6. doi: 10.1111/trf.14271

PMCID:: PMC5775889

Abstract Article PDF–2.8M

Select item 57041947.

Leukotriene B₄ receptor 2 gene polymorphism (rs1950504, Asp196Gly) leads to enhanced cell motility under low-dose ligand stimulation

Jae-Hyun Jang, Jun-Dong Wei, Minsup Kim, Joo-Young Kim, Art E Cho, Jae-Hong Kim

Exp Mol Med. 2017 Nov; 49(11): e402. Published online 2017 Nov 24. doi: 10.1038/emm.2017.192

PMCID:: PMC5704194

Abstract Article PDF–1.6M

Select item 56785818.

RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination

Nila Roy Choudhury, Gregory Heikel, Maryia Trubitsyna, Peter Kubik, Jakub Stanislaw Nowak, Shaun Webb, Sander Granneman, Christos Spanos, Juri Rappsilber, Alfredo Castello, Gracjan Michlewski

BMC Biol. 2017; 15: 105. Published online 2017 Nov 8. doi: 10.1186/s12915-017-0444-9

PMCID:: PMC5678581

Abstract Article PDF–3.2M

Select item 53717309.

Systematic protein–protein interaction mapping for clinically relevant human GPCRs

Kate Sokolina, Saranya Kittanakom, Jamie Snider, Max Kotlyar, Pascal Maurice, Jorge Gandía, Abla Benleulmi‐Chaachoua, Kenjiro Tadagaki, Atsuro Oishi, Victoria Wong, Ramy H Malty, Viktor Deineko, Hiroyuki Aoki, Shahreen Amin, Zhong Yao, Xavier Morató, David Otasek, Hiroyuki Kobayashi, Javier Menendez, Daniel Auerbach, Stephane Angers, Natasa Pržulj, Michel Bouvier, Mohan Babu, Francisco Ciruela, Ralf Jockers, Igor Jurisica, Igor Stagljar

Mol Syst Biol. 2017 Mar; 13(3): 918. Published online 2017 Mar 15. doi: 10.15252/msb.20167430

PMCID:: PMC5371730

Abstract Article PDF–4.1M

Select item 505052310.

Leukotriene B₄ receptor type 2 protects against pneumolysin-dependent acute lung injury

Misako Shigematsu, Tomoaki Koga, Ayako Ishimori, Kazuko Saeki, Yumiko Ishii, Yoshitaka Taketomi, Mai Ohba, Airi Jo-Watanabe, Toshiaki Okuno, Norihiro Harada, Takeshi Harayama, Hideo Shindou, Jian-Dong Li, Makoto Murakami, Sumio Hoka, Takehiko Yokomizo

Sci Rep. 2016; 6: 34560. Published online 2016 Oct 5. doi: 10.1038/srep34560

PMCID:: PMC5050523

Abstract Article PDF–990K

Select item 446739911.

Myeloid differentiation primary response gene 88-leukotriene B4 receptor 2 cascade mediates lipopolysaccharide-potentiated invasiveness of breast cancer cells

Geun-Soo Park, Jae-Hong Kim

Oncotarget. 2015 Mar 20; 6(8): 5749–5759. Published online 2015 Jan 21. doi: 10.18632/oncotarget.3304

PMCID:: PMC4467399

Abstract Article PDF–4.3M

Select item 413922812.

Ras Promotes Transforming Growth Factor-β (TGF-β)-induced Epithelial-Mesenchymal Transition via a Leukotriene B₄ Receptor-2-linked Cascade in Mammary Epithelial Cells

Hyunju Kim, Jung-A Choi, Jae-Hong Kim

J Biol Chem. 2014 Aug 8; 289(32): 22151–22160. Published online 2014 Jul 2. doi: 10.1074/jbc.M114.556126

PMCID:: PMC4139228

Abstract Article PDF–1.9M

Select item 379847413.

Activation of the Leukotriene B₄ Receptor 2-Reactive Oxygen Species (BLT2-ROS) Cascade following Detachment Confers Anoikis Resistance in Prostate Cancer Cells

Jin-Wook Lee, Jae-Hong Kim

J Biol Chem. 2013 Oct 18; 288(42): 30054–30063. Published online 2013 Aug 28. doi: 10.1074/jbc.M113.481283

PMCID:: PMC3798474

Abstract Article PDF–1.9M

Select item 377222114.

RanBPM Protein Acts as a Negative Regulator of BLT2 Receptor to Attenuate BLT2-mediated Cell Motility

Jun-Dong Wei, Joo-Young Kim, Ae-Kyoung Kim, Sung Key Jang, Jae-Hong Kim

J Biol Chem. 2013 Sep 13; 288(37): 26753–26763. Published online 2013 Aug 8. doi: 10.1074/jbc.M113.470260

PMCID:: PMC3772221

Abstract Article PDF–1.7M

Select item 372139815.

A leukotriene B₄ receptor-2 is associated with paclitaxel resistance in MCF-7/DOX breast cancer cells

H Kim, G-S Park, J E Lee, J-H Kim

Br J Cancer. 2013 Jul 23; 109(2): 351–359. Published online 2013 Jun 25. doi: 10.1038/bjc.2013.333

PMCID:: PMC3721398

Abstract Article PDF–1.3M

Select item 364719016.

Cigarette smoke increases BLT2 receptor functions in bronchial epithelial cells: in vitro and ex vivo evidence

Elisabetta Pace, Maria Ferraro, Serena Di Vincenzo, Andreina Bruno, Antonino Giarratano, Valeria Scafidi, Luana Lipari, Denise Valentina Di Benedetto, Serafina Sciarrino, Mark Gjomarkaj

Immunology. 2013 Jun; 139(2): 245–255. Published online 2013 Apr 23. doi: 10.1111/imm.12077