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Select item 105803621.

Upregulation of lysine‐specific demethylase 6B aggravates inflammatory pain through H3K27me3 demethylation‐dependent production of TNF‐α in the dorsal root ganglia and spinal dorsal horn in rats

Yiming Qiao, Liren Li, Liying Bai, Yan Gao, Yin Yang, Li Wang, Xueli Wang, Zongyi Liang, Ji‐Tian Xu

CNS Neurosci Ther. 2023 Nov; 29(11): 3479–3492. Published online 2023 Jun 8. doi: 10.1111/cns.14281

PMCID:: PMC10580362

Abstract Article PDF–8.7M

Select item 103419662.

KDM6B Negatively Regulates the Neurogenesis Potential of Apical Papilla Stem Cells via HES1

Chen Zhang, Weilong Ye, Mengyao Zhao, Lujue Long, Dengsheng Xia, Zhipeng Fan

Int J Mol Sci. 2023 Jul; 24(13): 10608. Published online 2023 Jun 25. doi: 10.3390/ijms241310608

PMCID:: PMC10341966

Abstract Article PDF–6.4M

Select item 88879993.

Lysine demethylase KDM6B regulates HIF-1α-mediated systemic and cellular responses to intermittent hypoxia

Jayasri Nanduri, Ning Wang, Benjamin L. Wang, Nanduri R. Prabhakar

Physiol Genomics. 2021 Sep 1; 53(9): 385–394. Published online 2021 Jul 23. doi: 10.1152/physiolgenomics.00045.2021

PMCID:: PMC8887999

Abstract Article

Select item 87079174.

Jmjd3 Mediates Neuropathic Pain by Inducing Macrophage Infiltration and Activation in Lumbar Spinal Stenosis Animal Model

Jeeyoun Lee, Haeyoung Choi, Chansol Park, Sangryong Jeon, Taeyoung Yune

Int J Mol Sci. 2021 Dec; 22(24): 13426. Published online 2021 Dec 14. doi: 10.3390/ijms222413426

PMCID:: PMC8707917

Abstract Article PDF–2.5M

Select item 78199955.

Polycomb represses a gene network controlling puberty via modulation of histone demethylase Kdm6b expression

Hollis Wright, Carlos F. Aylwin, Carlos A. Toro, Sergio R. Ojeda, Alejandro Lomniczi

Sci Rep. 2021; 11: 1996. Published online 2021 Jan 21. doi: 10.1038/s41598-021-81689-4

PMCID:: PMC7819995

Abstract Article PDF–5.5M

Select item 78064806.

Histone demethylase JMJD3 protects against renal fibrosis by suppressing TGFβ and Notch signaling and preserving PTEN expression

Chao Yu, Chongxiang Xiong, Jinhua Tang, Xiying Hou, Na Liu, George Bayliss, Shougang Zhuang

Theranostics. 2021; 11(6): 2706–2721. Published online 2021 Jan 1. doi: 10.7150/thno.48679

PMCID:: PMC7806480

Abstract Article PDF–4.0M

Select item 76810857.

Histone H3K27 methyltransferase EZH2 and demethylase JMJD3 regulate hepatic stellate cells activation and liver fibrosis

Yan Jiang, Chan Xiang, Fan Zhong, Yang Zhang, Liyan Wang, Yuanyuan Zhao, Jiucun Wang, Chen Ding, Li Jin, Fuchu He, Haijian Wang

Theranostics. 2021; 11(1): 361–378. Published online 2021 Jan 1. doi: 10.7150/thno.46360

PMCID:: PMC7681085

Abstract Article PDF–4.4M

Select item 71043148.

IL-4 Alleviates Ischaemia-Reperfusion Injury by Inducing Kupffer Cells M2 Polarization via STAT6-JMJD3 Pathway after Rat Liver Transplantation

Minghua Deng, Jingyuan Wang, Hao Wu, Menghao Wang, Ding Cao, Jinzheng Li, Yakun Wu, Jianping Gong

Biomed Res Int. 2020; 2020: 2953068. Published online 2020 Mar 18. doi: 10.1155/2020/2953068

PMCID:: PMC7104314

Abstract Article PDF–4.8M

Select item 53617379.

Potent and Selective KDM5 Inhibitor Stops Cellular Demethylation of H3K4me3 at Transcription Start Sites and Proliferation of MM1S Myeloma Cells

Anthony Tumber, Andrea Nuzzi, Edward S. Hookway, Stephanie B. Hatch, Srikannathasan Velupillai, Catrine Johansson, Akane Kawamura, Pavel Savitsky, Clarence Yapp, Aleksandra Szykowska, Na Wu, Chas Bountra, Claire Strain-Damerell, Nicola A. Burgess-Brown, Gian Filippo Ruda, Oleg Fedorov, Shonagh Munro, Katherine S. England, Radoslaw P. Nowak, Christopher J. Schofield, Nicholas B. La Thangue, Charlotte Pawlyn, Faith Davies, Gareth Morgan, Nick Athanasou, Susanne Müller, Udo Oppermann, Paul E. Brennan

Cell Chem Biol. 2017 Mar 16; 24(3): 371–380. Published online 2017 Mar 16. doi: 10.1016/j.chembiol.2017.02.006

PMCID:: PMC5361737

Abstract Article PDF–2.6M

Select item 482084210.

Neuronal activity controls Bdnf expression via Polycomb de-repression and CREB/CBP/JMJD3 activation in mature neurons

Ernest Palomer, Javier Carretero, Stefano Benvegnù, Carlos G. Dotti, Mauricio G. Martin

Nat Commun. 2016; 7: 11081. Published online 2016 Mar 24. doi: 10.1038/ncomms11081

PMCID:: PMC4820842

Abstract Article PDF–816K

Select item 467947811.

Jmjd3-mediated H3K27me3 dynamics orchestrate brown fat development and regulate white fat plasticity

Dongning Pan, Lei Huang, Lihua J. Zhu, Tie Zou, Jianhong Ou, William Zhou, Yong-Xu Wang

Dev Cell. Author manuscript; available in PMC 2016 Dec 7.

Published in final edited form as: Dev Cell. 2015 Dec 7; 35(5): 568–583. Published online 2015 Nov 25. doi: 10.1016/j.devcel.2015.11.002

PMCID:: PMC4679478

Abstract Article PDF–1.8M

Select item 394085712.

The signal transducers Stat1 and Stat3 and their novel target Jmjd3 drive the expression of inflammatory genes in microglia

Piotr Przanowski, Michal Dabrowski, Aleksandra Ellert-Miklaszewska, Michal Kloss, Jakub Mieczkowski, Beata Kaza, Anna Ronowicz, Feng Hu, Arkadiusz Piotrowski, Helmut Kettenmann, Jan Komorowski, Bozena Kaminska

J Mol Med (Berl) 2014; 92(3): 239–254. Published online 2013 Oct 6. doi: 10.1007/s00109-013-1090-5

PMCID:: PMC3940857

Abstract Article PDF–1.1M

Select item 386105813.

Histone Lysine Methylation Dynamics: Establishment, Regulation, and Biological Impact

Joshua C. Black, Capucine Van Rechem, Johnathan R. Whetstine

Mol Cell. Author manuscript; available in PMC 2013 Dec 12.

Published in final edited form as: Mol Cell. 2012 Nov 30; 48(4): 10.1016/j.molcel.2012.11.006. doi: 10.1016/j.molcel.2012.11.006

PMCID:: PMC3861058

Abstract Article PDF–2.1M

Select item 353176414.

Histone Demethylase KDM6B Promotes Epithelial-Mesenchymal Transition

Sivakumar Ramadoss, Xiaohong Chen, Cun-Yu Wang

J Biol Chem. 2012 Dec 28; 287(53): 44508–44517. Published online 2012 Nov 14. doi: 10.1074/jbc.M112.424903

Correction in:: J Biol Chem. 2020 May 8; 295(19): 6781.

PMCID:: PMC3531764

Abstract Article PDF–2.3M

Select item 352086815.

Expression and significance of histone H3K27 demethylases in renal cell carcinoma

Yongqing Shen, Xiaoqiang Guo, Yuejia Wang, Wei Qiu, Yanzhong Chang, Aili Zhang, Xianglin Duan

BMC Cancer. 2012; 12: 470. Published online 2012 Oct 12. doi: 10.1186/1471-2407-12-470

PMCID:: PMC3520868

Abstract Article PDF–1.5M

Select item 331957016.

Coexpression of Nuclear Receptors and Histone Methylation Modifying Genes in the Testis: Implications for Endocrine Disruptor Modes of Action

Alison M. Anderson, Kim W. Carter, Denise Anderson, Michael J. Wise

PLoS One. 2012; 7(4): e34158. Published online 2012 Apr 4. doi: 10.1371/journal.pone.0034158

PMCID:: PMC3319570

Abstract Article PDF–1.3M

Select item 317805917.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 303226618.

Jmjd3 and UTX play a demethylase-independent role in chromatin remodeling to regulate T-box family member-dependent gene expression

Sara A. Miller, Sarah E. Mohn, Amy S. Weinmann

Mol Cell. Author manuscript; available in PMC 2011 Nov 24.

Published in final edited form as: Mol Cell. 2010 Nov 24; 40(4): 594–605. doi: 10.1016/j.molcel.2010.10.028

PMCID:: PMC3032266

Abstract Article PDF–1.7M

Select item 292743719.

A Novel Zinc Finger Protein Zfp277 Mediates Transcriptional Repression of the Ink4a/Arf Locus through Polycomb Repressive Complex 1

Masamitsu Negishi, Atsunori Saraya, Shinobu Mochizuki, Kristian Helin, Haruhiko Koseki, Atsushi Iwama

PLoS One. 2010; 5(8): e12373. Published online 2010 Aug 24. doi: 10.1371/journal.pone.0012373

PMCID:: PMC2927437

Abstract Article PDF–1.2M

Select item 280223420.

Rat hd Mutation Reveals an Essential Role of Centrobin in Spermatid Head Shaping and Assembly of the Head-Tail Coupling Apparatus

František Liška, Claudia Gosele, Eugene Rivkin, Laura Tres, M. Cristina Cardoso, Petra Domaing, Eliška Krejčí, Pavel Šnajdr, Min Ae Lee-Kirsch, Dirk G. de Rooij, Vladimír Křen, Drahomíra Křenová, Abraham L. Kierszenbaum, Norbert Hubner

Biol Reprod. 2009 Dec; 81(6): 1196–1205. Published online 2009 Aug 26. doi: 10.1095/biolreprod.109.078980

Correction in:: Biol Reprod. 2010 Apr 1; 82(4): 804.

PMCID:: PMC2802234

Abstract Article PDF–4.3M

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