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Select item 111155971.

The metazoan ATAC and SAGA coactivator HAT complexes regulate different sets of inducible target genes

Zita Nagy, Anne Riss, Sally Fujiyama, Arnaud Krebs, Meritxell Orpinell, Pascal Jansen, Adrian Cohen, Henk G. Stunnenberg, Shigeaki Kato, Làszlò Tora

Cell Mol Life Sci. 2010 Feb; 67(4): 611–628. Published online 2009 Nov 21. doi: 10.1007/s00018-009-0199-8

PMCID:: PMC11115597

Abstract Article PDF–816K

Select item 110911182.

GCN5 mediates DNA-PKcs crotonylation for DNA double-strand break repair and determining cancer radiosensitivity

Yang Han, Hongling Zhao, Gang Li, Jin Jia, Hejiang Guo, Jinpeng Tan, Xingyao Sun, Saiyu Li, Qian Ran, Chenjun Bai, Yongqing Gu, ZhongJun Li, Hua Guan, Shanshan Gao, Ping-Kun Zhou

Br J Cancer. 2024 Jun 1; 130(10): 1621–1634. Published online 2024 Apr 4. doi: 10.1038/s41416-024-02636-4

PMCID:: PMC11091118

Abstract Article PDF–3.0M

Select item 105918363.

ATAC and SAGA co-activator complexes utilize co-translational assembly, but their cellular localization properties and functions are distinct

Gizem Yayli, Andrea Bernardini, Paulina Karen Mendoza Sanchez, Elisabeth Scheer, Mylène Damilot, Karim Essabri, Bastien Morlet, Luc Negroni, Stéphane D. Vincent, H.T. Marc Timmers, László Tora

Cell Rep. Author manuscript; available in PMC 2023 Oct 23.

Published in final edited form as: Cell Rep. 2023 Sep 26; 42(9): 113099. Published online 2023 Sep 8. doi: 10.1016/j.celrep.2023.113099

PMCID:: PMC10591836

Abstract Article PDF–2.6M

Select item 102806144.

Regulatory mechanisms of GCN5 in osteogenic differentiation of MSCs in periodontitis

Wei Lu, Li Zhang, Kun Ji, Ling Ding, Guofeng Wu

Clin Exp Dent Res. 2023 Jun; 9(3): 464–471. Published online 2023 Apr 6. doi: 10.1002/cre2.695

PMCID:: PMC10280614

Abstract Article PDF–1.0M

Select item 96021695.

KAT2A/E2F1 Promotes Cell Proliferation and Migration via Upregulating the Expression of UBE2C in Pan-Cancer

Shudai Lin, Li Qiu, Keying Liang, Haibo Zhang, Mingjian Xian, Zixi Chen, Jinfen Wei, Shuying Fu, Xiaocheng Gong, Ke Ding, Zihao Zhang, Bowen Hu, Xiquan Zhang, Yuyou Duan, Hongli Du

Genes (Basel) 2022 Oct; 13(10): 1817. Published online 2022 Oct 8. doi: 10.3390/genes13101817

PMCID:: PMC9602169

Abstract Article PDF–5.1M

Select item 94540906.

The Acyl-CoA Specificity of Human Lysine Acetyltransferase KAT2A

Ananya Anmangandla, Yuxiang Ren, Qin Fu, Sheng Zhang, Hening Lin

Biochemistry. 2022 Sep 6; 61(17): 1874–1882. Published online 2022 Aug 22. doi: 10.1021/acs.biochem.2c00308

PMCID:: PMC9454090

Abstract Article PDF–6.6M

Select item 93576627.

H1.0 induces paclitaxel‐resistance genes expression in ovarian cancer cells by recruiting GCN5 and androgen receptor

Abhidha Kohli, Shang‐Lang Huang, Ting‐Chang Chang, Chuck C.‐K. Chao, Nian‐Kang Sun

Cancer Sci. 2022 Aug; 113(8): 2616–2626. Published online 2022 Jun 13. doi: 10.1111/cas.15448

PMCID:: PMC9357662

Abstract Article PDF–3.3M

Select item 92626148.

A dual-activity topoisomerase complex regulates mRNA translation and turnover

Shuaikun Su, Yutong Xue, Alexei Sharov, Yongqing Zhang, Seung Kyu Lee, Jennifer L Martindale, Wen Li, Wai Lim Ku, Keji Zhao, Supriyo De, Weiping Shen, Payel Sen, Myriam Gorospe, Dongyi Xu, Weidong Wang

Nucleic Acids Res. 2022 Jul 8; 50(12): 7013–7033. Published online 2022 Jun 24. doi: 10.1093/nar/gkac538

PMCID:: PMC9262614

Abstract Article PDF–3.6M

Select item 91754829.

LukS-PV inhibits hepatocellular carcinoma cells migration by downregulating HDAC6 expression

Xuexue Xu, Pengsheng Ding, Lan Shi, Gang Wu, Xiaoling Ma

BMC Cancer. 2022; 22: 630. Published online 2022 Jun 8. doi: 10.1186/s12885-022-09680-4

PMCID:: PMC9175482

Abstract Article PDF–15M

Select item 911973610.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 882889511.

Human transcription factor protein interaction networks

Helka Göös, Matias Kinnunen, Kari Salokas, Zenglai Tan, Xiaonan Liu, Leena Yadav, Qin Zhang, Gong-Hong Wei, Markku Varjosalo

Nat Commun. 2022; 13: 766. Published online 2022 Feb 9. doi: 10.1038/s41467-022-28341-5

PMCID:: PMC8828895

Abstract Article PDF–1.7M

Select item 875320712.

KAT2A complexes ATAC and SAGA play unique roles in cell maintenance and identity in hematopoiesis and leukemia

Liliana Arede, Elena Foerner, Selinde Wind, Rashmi Kulkarni, Ana Filipa Domingues, George Giotopoulos, Svenja Kleinwaechter, Maximilian Mollenhauer-Starkl, Holly Davison, Aditya Chandru, Ryan Asby, Ralph Samarista, Shikha Gupta, Dorian Forte, Antonio Curti, Elisabeth Scheer, Brian J. P. Huntly, Laszlo Tora, Cristina Pina

Blood Adv. 2022 Jan 11; 6(1): 165–180. Published online 2022 Jan 7. doi: 10.1182/bloodadvances.2020002842

PMCID:: PMC8753207

Abstract Article PDF–2.3M

Select item 869622013.

P300/CBP‐associated factor (PCAF)‐mediated acetylation of Fascin at lysine 471 inhibits its actin‐bundling activity and tumor metastasis in esophageal cancer

Yin‐Wei Cheng, Fa‐Min Zeng, Da‐Jia Li, Shao‐Hong Wang, Jian‐Zhong He, Zhen‐Chang Guo, Ping‐Juan Nie, Zhi‐Yong Wu, Wen‐Qi Shi, Bing Wen, Xiu‐E Xu, Lian‐Di Liao, Zhi‐Mao Li, Jian‐Yi Wu, Jun Zhan, Hong‐Quan Zhang, Zhi‐Jie Chang, Kai Zhang, Li‐Yan Xu, En‐Min Li

Cancer Commun (Lond) 2021 Dec; 41(12): 1398–1416. Published online 2021 Sep 23. doi: 10.1002/cac2.12221

PMCID:: PMC8696220

Abstract Article PDF–5.3M

Select item 855721114.

A preliminary study of KAT2A on cGAS-related immunity in inflammation amplification of systemic lupus erythematosus

Youzhou Tang, Xinyu Li, Yafang Wei, Yongchao Sun, Yeyi Yang, Xianming Zhang, Zhihao Gao, Jishi Liu, Quan Zhuang

Cell Death Dis. 2021 Nov; 12(11): 1036. Published online 2021 Oct 30. doi: 10.1038/s41419-021-04323-1

PMCID:: PMC8557211

Abstract Article PDF–4.5M

Select item 838659815.

Autophagic degradation of KAT2A/GCN5 promotes directional migration of vascular smooth muscle cells by reducing TUBA/α-tubulin acetylation

Changhan Ouyang, Jing Mu, Qiulun Lu, Jian Li, Huaiping Zhu, Qilong Wang, Ming-Hui Zou, Zhonglin Xie

Autophagy. 2020; 16(10): 1753–1770. Published online 2019 Dec 27. doi: 10.1080/15548627.2019.1707488

PMCID:: PMC8386598

Abstract Article PDF–8.2M

Select item 835791516.

KAT2A-mediated AR translocation into nucleus promotes abiraterone-resistance in castration-resistant prostate cancer

Dingheng Lu, Yarong Song, Ying Yu, Decai Wang, Bing Liu, Liang Chen, Xuexiang Li, Yunxue Li, Lulin Cheng, Fang Lv, Pu Zhang, Yifei Xing

Cell Death Dis. 2021 Aug; 12(8): 787. Published online 2021 Aug 12. doi: 10.1038/s41419-021-04077-w

PMCID:: PMC8357915

Abstract Article PDF–4.2M

Select item 822039117.

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα

Evelyn Ramberger, Valeria Sapozhnikova, Elisabeth Kowenz-Leutz, Karin Zimmermann, Nathalie Nicot, Petr V. Nazarov, Daniel Perez-Hernandez, Ulf Reimer, Philipp Mertins, Gunnar Dittmar, Achim Leutz

iScience. 2021 Jun 25; 24(6): 102686. Published online 2021 Jun 4. doi: 10.1016/j.isci.2021.102686

PMCID:: PMC8220391

Abstract Article PDF–4.4M

Select item 820839918.

GCN5 acetyltransferase inhibits PGC1α-induced hepatitis B virus biosynthesis

Xiaohui Tian, Fei Zhao, Zhikui Cheng, Ming Zhou, Xiaoguang Zhi, Jiafu Li, Kanghong Hu

Virol Sin. 2013 Aug; 28(4): 216–222. Published online 2013 Jul 2. doi: 10.1007/s12250-013-3344-3

PMCID:: PMC8208399

Abstract Article PDF–556K

Select item 816503019.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 810809320.

DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity

Rajat Gupta, Kumar Somyajit, Takeo Narita, Elina Maskey, Andre Stanlie, Magdalena Kremer, Dimitris Typas, Michael Lammers, Niels Mailand, Andre Nussenzweig, Jiri Lukas, Chunaram Choudhary

Cell. Author manuscript; available in PMC 2021 May 10.

Published in final edited form as: Cell. 2018 May 3; 173(4): 972–988.e23. Published online 2018 Apr 12. doi: 10.1016/j.cell.2018.03.050

PMCID:: PMC8108093

Abstract Article PDF–3.5M

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