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Select item 113735991.

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway

Elena Prosdocimi, Veronica Carpanese, Luca Matteo Todesca, Tatiana Varanita, Magdalena Bachmann, Margherita Festa, Daniele Bonesso, Mireia Perez-Verdaguer, Andrea Carrer, Angelo Velle, Roberta Peruzzo, Silvia Muccioli, Davide Doni, Luigi Leanza, Paola Costantini, Frank Stein, Mandy Rettel, Antonio Felipe, Michael J. Edwards, Erich Gulbins, Laura Cendron, Chiara Romualdi, Vanessa Checchetto, Ildiko Szabo

Sci Adv. 2024 Sep 6; 10(36): eadn9361. Published online 2024 Sep 4. doi: 10.1126/sciadv.adn9361

PMCID:: PMC11373599

Abstract Article PDF–11M

Select item 112099352.

Antagonistic roles of canonical and alternative-RPA in disease-associated tandem CAG repeat instability

Terence Gall-Duncan, Jennifer Luo, Carla-Marie Jurkovic, Laura A. Fischer, Kyota Fujita, Amit L. Deshmukh, Rachel J. Harding, Stephanie Tran, Mustafa Mehkary, Vanessa Li, David E. Leib, Ran Chen, Hikari Tanaka, Amanda G. Mason, Dominique Lévesque, Mahreen Khan, Mortezaali Razzaghi, Tanya Prasolava, Stella Lanni, Nozomu Sato, Marie-Christine Caron, Gagan B. Panigrahi, Peixiang Wang, Rachel Lau, Arturo López Castel, Jean-Yves Masson, Lynette Tippett, Clinton Turner, Maria Spies, Albert R. La Spada, Eric I. Campos, Maurice A. Curtis, François-Michel Boisvert, Richard L.M. Faull, Beverly L. Davidson, Masayuki Nakamori, Hitoshi Okazawa, Marc S. Wold, Christopher E. Pearson

Cell. Author manuscript; available in PMC 2024 Oct 26.

Published in final edited form as: Cell. 2023 Oct 26; 186(22): 4898–4919.e25. Published online 2023 Oct 11. doi: 10.1016/j.cell.2023.09.008

PMCID:: PMC11209935

Abstract Article PDF–3.0M

Select item 109902773.

ER-export and ARFRP1/AP-1–dependent delivery of SARS-CoV-2 Envelope to lysosomes controls late stages of viral replication

Guy J. Pearson, Harriet V. Mears, Malgorzata Broncel, Ambrosius P. Snijders, David L. V. Bauer, Jeremy G. Carlton

Sci Adv. 2024 Apr 5; 10(14): eadl5012. Published online 2024 Apr 3. doi: 10.1126/sciadv.adl5012

PMCID:: PMC10990277

Abstract Article PDF–3.9M

Select item 107597194.

Identification and validation of voltage‐dependent anion channel 1‐related genes and immune cell infiltration in diabetic nephropathy

Jiaqun Lin, Mengjie Weng, Jing Zheng, Kun Nie, Siyi Rao, Yongjie Zhuo, Jianxin Wan

J Diabetes Investig. 2024 Jan; 15(1): 87–105. Published online 2023 Sep 22. doi: 10.1111/jdi.14087

PMCID:: PMC10759719

Abstract Article PDF–11M

Select item 107096375.

Phospholipids are imported into mitochondria by VDAC, a dimeric beta barrel scramblase

Helene Jahn, Ladislav Bartoš, Grace I. Dearden, Jeremy S. Dittman, Joost C. M. Holthuis, Robert Vácha, Anant K. Menon

Nat Commun. 2023; 14: 8115. Published online 2023 Dec 8. doi: 10.1038/s41467-023-43570-y

PMCID:: PMC10709637

Abstract Article PDF–2.4M

Select item 106176736.

The midnolin-proteasome pathway catches proteins for ubiquitination-independent degradation

Xin Gu, Christopher Nardone, Nolan Kamitaki, Aoyue Mao, Stephen J. Elledge, Michael E. Greenberg

Science. Author manuscript; available in PMC 2023 Oct 31.

Published in final edited form as: Science. 2023 Aug 25; 381(6660): eadh5021. Published online 2023 Aug 25. doi: 10.1126/science.adh5021

PMCID:: PMC10617673

Abstract Article PDF–3.6M

Select item 105658767.

Pulse-SILAC and Interactomics Reveal Distinct DDB1-CUL4–Associated Factors, Cellular Functions, and Protein Substrates

Jennifer Raisch, Marie-Line Dubois, Marika Groleau, Dominique Lévesque, Thomas Burger, Carla-Marie Jurkovic, Romain Brailly, Gwendoline Marbach, Alyson McKenna, Catherine Barrette, Pierre-Étienne Jacques, François-Michel Boisvert

Mol Cell Proteomics. 2023 Oct; 22(10): 100644. Published online 2023 Sep 7. doi: 10.1016/j.mcpro.2023.100644

PMCID:: PMC10565876

Abstract Article PDF–3.7M

Select item 105140818.

HSP90 C-terminal domain inhibition promotes VDAC1 oligomerization via decreasing K274 mono-ubiquitination in Hepatocellular Carcinoma

Jinxin Zhang, Lixia Liu, Yan Li, Yaling Huang, Senbo Xiao, Zihao Deng, Zhenming Zheng, Jieyou Li, Manfeng Liang, Guantai Xie, Xiao Chen, Yaotang Deng, Wenchong Tan, Hairou Su, Guibing Wu, Chunqing Cai, Xuemei Chen, Fei Zou

Neoplasia. 2023 Oct; 44: 100935. Published online 2023 Sep 15. doi: 10.1016/j.neo.2023.100935

PMCID:: PMC10514081

Abstract Article PDF–14M

Select item 103986609.

C9orf72 protein quality control by UBR5‐mediated heterotypic ubiquitin chains

Julia Jülg, Dieter Edbauer, Christian Behrends

EMBO Rep. 2023 Aug; 24(8): e55895. Published online 2023 Jun 15. doi: 10.15252/embr.202255895

PMCID:: PMC10398660

Abstract Article PDF–2.4M

Select item 1039715510.

Evaluation of copper-induced biomolecular changes in different porin mutants of Escherichia coli W3110 by infrared spectroscopy

Gulcin Cetin Kilicaslan, Rafig Gurbanov, Cihan Darcan

J Biol Phys. 2023 Sep; 49(3): 309–327. Published online 2023 Apr 3. doi: 10.1007/s10867-023-09632-4

PMCID:: PMC10397155

Abstract Article PDF–3.6M

Select item 1039273211.

Hypoxia-induced GPCPD1 depalmitoylation triggers mitophagy via regulating PRKN-mediated ubiquitination of VDAC1

Ying Liu, Hanwen Zhang, Yiwei Liu, Siyue Zhang, Peng Su, Lijuan Wang, Yaming Li, Yiran Liang, Xiaolong Wang, Weijing Zhao, Bing Chen, Dan Luo, Ning Zhang, Qifeng Yang

Autophagy. 2023; 19(9): 2443–2463. Published online 2023 Mar 1. doi: 10.1080/15548627.2023.2182482

PMCID:: PMC10392732

Abstract Article PDF–10M

Select item 1030836512.

A mitochondrial SCF‐FBXL4 ubiquitin E3 ligase complex degrades BNIP3 and NIX to restrain mitophagy and prevent mitochondrial disease

Yu Cao, Jing Zheng, Huayun Wan, Yuqiu Sun, Song Fu, Shanshan Liu, Baiyu He, Gaihong Cai, Yang Cao, Huanwei Huang, Qi Li, Yan Ma, She Chen, Fengchao Wang, Hui Jiang

EMBO J. 2023 Jul; 42(13): e113033. Published online 2023 Mar 10. doi: 10.15252/embj.2022113033

PMCID:: PMC10308365

Abstract Article PDF–5.2M

Select item 1028411713.

Exploring an Alternative Cysteine-Reactive Chemistry to Enable Proteome-Wide PPI Analysis by Cross-Linking Mass Spectrometry

Fenglong Jiao, Leah J. Salituro, Clinton Yu, Craig B. Gutierrez, Scott D. Rychnovsky, Lan Huang

Anal Chem. Author manuscript; available in PMC 2023 Jun 21.

Published in final edited form as: Anal Chem. 2023 Jan 31; 95(4): 2532–2539. Published online 2023 Jan 18. doi: 10.1021/acs.analchem.2c04986

PMCID:: PMC10284117

Abstract Article PDF–2.5M

Select item 1025678614.

HNF4A-BAP31-VDAC1 axis synchronously regulates cell proliferation and ferroptosis in gastric cancer

Qingqing Zhou, Tengfei Liu, Wenjing Qian, Jun Ji, Qu Cai, Yangbing Jin, Jinling Jiang, Jun Zhang

Cell Death Dis. 2023 Jun; 14(6): 356. Published online 2023 Jun 9. doi: 10.1038/s41419-023-05868-z

PMCID:: PMC10256786

Abstract Article PDF–7.6M

Select item 1024339815.

Evolution of Mycobacterium abscessus in the human lung: Cumulative mutations and genomic rearrangement of porin genes in patient isolates

Shamira J. Shallom, Hervé Tettelin, Prabha Chandrasekaran, In Kwon Park, Sonia Agrawal, Kriti Arora, Lisa Sadzewicz, Aaron M. Milstone, Moira L. Aitken, Barbara A. Brown-Elliott, Richard J. Wallace, Jr, Elizabeth P. Sampaio, Michael Niederweis, Kenneth N. Olivier, Steven M. Holland, Adrian M. Zelazny

Virulence. 2023; 14(1): 2215602. Published online 2023 Jun 4. doi: 10.1080/21505594.2023.2215602

PMCID:: PMC10243398

Abstract Article PDF–1.8M

Select item 1023742216.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233