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Items: 1 to 20 of 29

1.
Topoisomerase I Inhibition Radiosensitizing Hepatocellular Carcinoma by RNF144A-mediated DNA-PKcs Ubiquitination and Natural Killer Cell Cytotoxicity
Chiao-Ling Tsai, Po-Sheng Yang, Feng-Ming Hsu, Ann-Lii Cheng, Wan-Ni Yu, Jason Chia-Hsien Cheng
J Clin Transl Hepatol. 2023 Jun 28; 11(3): 614–625. Published online 2023 Jan 4. doi: 10.14218/JCTH.2022.00271
PMCID:
PMC10037509
AbstractArticlePDF–10M
2.
RNF144A Deficiency Promotes PD-L1 Protein Stabilization and Carcinogen-Induced Bladder Tumorigenesis
Shiuh-Rong Ho, Yu-Cheng Lee, Michael M. Ittmann, Fang-Tsyr Lin, Keith Syson Chan, Weei-Chin Lin
Cancer Lett. Author manuscript; available in PMC 2022 Nov 1.
Published in final edited form as: Cancer Lett. 2021 Nov 1; 520: 344–360. Published online 2021 Aug 13. doi: 10.1016/j.canlet.2021.08.008
PMCID:
PMC9420248
AbstractArticlePDF–3.4M
3.
RNF144A exerts tumor suppressor function in breast cancer through targeting YY1 for proteasomal degradation to downregulate GMFG expression
Yin-Ling Zhang, Jin-Ling Cao, Ye Zhang, Li Liao, Ling Deng, Shao-Ying Yang, Shu-Yuan Hu, Yan Ning, Fang-Lin Zhang, Da-Qiang Li
Med Oncol. 2022; 39(4): 48. Published online 2022 Feb 1. doi: 10.1007/s12032-021-01631-6
PMCID:
PMC8807444
AbstractArticlePDF–4.8M
4.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
5.
Solution structure of the zinc finger domain of human RNF144A ubiquitin ligase
Kazuhide Miyamoto, Kaori Migita, Kazuki Saito
Protein Sci. 2020 Aug; 29(8): 1836–1842. Published online 2020 Jul 13. doi: 10.1002/pro.3903
PMCID:
PMC7380669
AbstractArticlePDF–1.4M
6.
RNF144A functions as a tumor suppressor in breast cancer through ubiquitin ligase activity-dependent regulation of stability and oncogenic functions of HSPA2
Yin-Long Yang, Ye Zhang, Dou-Dou Li, Fang-Lin Zhang, Hong-Yi Liu, Xiao-Hong Liao, Hong-Yan Xie, Qin Lu, Lin Zhang, Qi Hong, Wen-Jie Dong, Da-Qiang Li, Zhi-Min Shao
Cell Death Differ. 2020 Mar; 27(3): 1105–1118. Published online 2019 Aug 13. doi: 10.1038/s41418-019-0400-z
PMCID:
PMC7205990
AbstractArticlePDF–4.1M
7.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
8.
DHHC protein family targets different subsets of glioma stem cells in specific niches
Xueran Chen, Lei Hu, Haoran Yang, Huihui Ma, Kaiqin Ye, Chenggang Zhao, Zhiyang Zhao, Haiming Dai, Hongzhi Wang, Zhiyou Fang
J Exp Clin Cancer Res. 2019; 38: 25. Published online 2019 Jan 18. doi: 10.1186/s13046-019-1033-2
PMCID:
PMC6339410
AbstractArticlePDF–8.1M
9.
RNF144A sustains EGFR signaling to promote EGF-dependent cell proliferation
Shiuh-Rong Ho, Weei-Chin Lin
J Biol Chem. 2018 Oct 19; 293(42): 16307–16323. Published online 2018 Aug 31. doi: 10.1074/jbc.RA118.002887
PMCID:
PMC6200932
AbstractArticlePDF–6.2M
10.
Epigenetic silencing of RNF144A expression in breast cancer cells through promoter hypermethylation and MBD4
Ye Zhang, Yin‐Long Yang, Fang‐Lin Zhang, Xiao‐Hong Liao, Zhi‐Min Shao, Da‐Qiang Li
Cancer Med. 2018 Apr; 7(4): 1317–1325. Published online 2018 Feb 23. doi: 10.1002/cam4.1324
PMCID:
PMC5911569
AbstractArticlePDF–349K
11.
Determinants of E2-ubiquitin conjugate recognition by RBR E3 ligases
Luigi Martino, Nicholas R. Brown, Laura Masino, Diego Esposito, Katrin Rittinger
Sci Rep. 2018; 8: 68. Published online 2018 Jan 8. doi: 10.1038/s41598-017-18513-5
PMCID:
PMC5758712
AbstractArticlePDF–5.1M
12.
RBR-type E3 ubiquitin ligase RNF144A targets PARP1 for ubiquitin-dependent degradation and regulates PARP inhibitor sensitivity in breast cancer cells
Ye Zhang, Xiao-Hong Liao, Hong-Yan Xie, Zhi-Min Shao, Da-Qiang Li
Oncotarget. 2017 Nov 7; 8(55): 94505–94518. Published online 2017 Oct 10. doi: 10.18632/oncotarget.21784
PMCID:
PMC5706891
AbstractArticlePDF–3.1M
13.
Ubiquitin Linkage-Specific Affimers Reveal Insights into K6-Linked Ubiquitin Signaling
Martin A. Michel, Kirby N. Swatek, Manuela K. Hospenthal, David Komander
Mol Cell. 2017 Oct 5; 68(1): 233–246.e5. doi: 10.1016/j.molcel.2017.08.020
PMCID:
PMC5640506
AbstractArticle
14.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
15.
Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing
Teng Fei, Yiwen Chen, Tengfei Xiao, Wei Li, Laura Cato, Peng Zhang, Maura B. Cotter, Michaela Bowden, Rosina T. Lis, Shuang G. Zhao, Qiu Wu, Felix Y. Feng, Massimo Loda, Housheng Hansen He, X. Shirley Liu, Myles Brown
Proc Natl Acad Sci U S A. 2017 Jun 27; 114(26): E5207–E5215. Published online 2017 Jun 13. doi: 10.1073/pnas.1617467114
PMCID:
PMC5495225
AbstractArticlePDF–1.3M
16.
Systematic protein–protein interaction mapping for clinically relevant human GPCRs
Kate Sokolina, Saranya Kittanakom, Jamie Snider, Max Kotlyar, Pascal Maurice, Jorge Gandía, Abla Benleulmi‐Chaachoua, Kenjiro Tadagaki, Atsuro Oishi, Victoria Wong, Ramy H Malty, Viktor Deineko, Hiroyuki Aoki, Shahreen Amin, Zhong Yao, Xavier Morató, David Otasek, Hiroyuki Kobayashi, Javier Menendez, Daniel Auerbach, Stephane Angers, Natasa Pržulj, Michel Bouvier, Mohan Babu, Francisco Ciruela, Ralf Jockers, Igor Jurisica, Igor Stagljar
Mol Syst Biol. 2017 Mar; 13(3): 918. Published online 2017 Mar 15. doi: 10.15252/msb.20167430
PMCID:
PMC5371730
AbstractArticlePDF–4.1M
17.
Molecular insights into RBR E3 ligase ubiquitin transfer mechanisms
Katja K Dove, Benjamin Stieglitz, Emily D Duncan, Katrin Rittinger, Rachel E Klevit
EMBO Rep. 2016 Aug; 17(8): 1221–1235. Published online 2016 Jun 16. doi: 10.15252/embr.201642641
PMCID:
PMC4967960
AbstractArticlePDF–3.2M
18.
Regulation of RNF144A E3 Ubiquitin Ligase Activity by Self-association through Its Transmembrane Domain
Shiuh-Rong Ho, Yu-Ju Lee, Weei-Chin Lin
J Biol Chem. 2015 Sep 18; 290(38): 23026–23038. Published online 2015 Jul 27. doi: 10.1074/jbc.M115.645499
PMCID:
PMC4645615
AbstractArticlePDF–3.6M
19.
The BioPlex Network: A Systematic Exploration of the Human Interactome
Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2016 Jul 16.
Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043
PMCID:
PMC4617211
AbstractArticlePDF–2.2M
20.
RNF144A, an E3 ubiquitin ligase for DNA-PKcs, promotes apoptosis during DNA damage
Shiuh-Rong Ho, Christina S. Mahanic, Yu-Ju Lee, Weei-Chin Lin
Proc Natl Acad Sci U S A. 2014 Jul 1; 111(26): E2646–E2655. Published online 2014 Jun 16. doi: 10.1073/pnas.1323107111
PMCID:
PMC4084471
AbstractArticlePDF–1.8M

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