PMC Links for GEO Profiles (Select 25020021) - PMC

Noreen McBrearty, Christina Cho, Jinyun Chen, Farima Zahedi, Amy R. Peck, Enrico Radaelli, Charles-Antoine Assenmacher, Clarice Pavlak, Anne Devine, Pengfei Yu, Zhen Lu, Hongru Zhang, Jinyang Li, Jason R. Pitarresi, Igor Astsaturov, Edna Cukierman, Anil K. Rustgi, Ben Z. Stanger, Hallgeir Rui, Serge Y. Fuchs

Mol Cancer Res. Author manuscript; available in PMC 2023 Sep 1.

Published in final edited form as: Mol Cancer Res. 2023 Mar 1; 21(3): 228–239. doi: 10.1158/1541-7786.MCR-22-0602

PMCID:: PMC9992122

Abstract Article PDF–1.9M

Select item 77493314.

Cholesterol 25-hydroxylase suppresses SARS-CoV-2 replication by blocking membrane fusion

Ruochen Zang, James Brett Case, Eylan Yutuc, Xiucui Ma, Sheng Shen, Maria Florencia Gomez Castro, Zhuoming Liu, Qiru Zeng, Haiyan Zhao, Juhee Son, Paul W. Rothlauf, Alex J. B. Kreutzberger, Gaopeng Hou, Hu Zhang, Sayantan Bose, Xin Wang, Michael D. Vahey, Kartik Mani, William J. Griffiths, Tom Kirchhausen, Daved H. Fremont, Haitao Guo, Abhinav Diwan, Yuqin Wang, Michael S. Diamond, Sean P. J. Whelan, Siyuan Ding

Proc Natl Acad Sci U S A. 2020 Dec 15; 117(50): 32105–32113. Published online 2020 Nov 25. doi: 10.1073/pnas.2012197117

PMCID:: PMC7749331

Abstract Article PDF–1.4M

Select item 75370455.

Cholesterol 25‐Hydroxylase inhibits SARS‐CoV‐2 and other coronaviruses by depleting membrane cholesterol

Shaobo Wang, Wanyu Li, Hui Hui, Shashi Kant Tiwari, Qiong Zhang, Ben A Croker, Stephen Rawlings, Davey Smith, Aaron F Carlin, Tariq M Rana

EMBO J. 2020 Nov 2; 39(21): e106057. Published online 2020 Oct 5. doi: 10.15252/embj.2020106057

PMCID:: PMC7537045

Abstract Article PDF–3.1M

Select item 72677356.

Cholesterol 25-hydroxylase (CH25H) as a promoter of adipose tissue inflammation in obesity and diabetes

Lucia Russo, Lindsey Muir, Lynn Geletka, Jennifer Delproposto, Nicki Baker, Carmen Flesher, Robert O'Rourke, Carey N. Lumeng

Mol Metab. 2020 Sep; 39: 100983. Published online 2020 Mar 27. doi: 10.1016/j.molmet.2020.100983

PMCID:: PMC7267735

Abstract Article PDF–3.6M

Select item 71699837.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 67794488.

IL-1β/TNF-α/IL-6 inflammatory cytokines promote STAT1-dependent induction of CH25H in Zika virus–infected human macrophages

Tshifhiwa Magoro, Aditya Dandekar, Lucas T. Jennelle, Rohan Bajaj, Gabriel Lipkowitz, Angelina R. Angelucci, Pascal O. Bessong, Young S. Hahn

J Biol Chem. 2019 Oct 4; 294(40): 14591–14602. Published online 2019 Aug 2. doi: 10.1074/jbc.RA119.007555

PMCID:: PMC6779448

Abstract Article PDF–1.6M

Select item 63361149.

An interferon-driven oxysterol-based defense against tumor-derived extracellular vesicles

Angelica Ortiz, Jun Gui, Farima Zahedi, Pengfei Yu, Christina Cho, Sabyasachi Bhattacharya, Christopher J. Carbone, Qiujing Yu, Kanstantsin V. Katlinski, Yuliya V. Katlinskaya, Simran Handa, Victor Haas, Susan W. Volk, Angela K. Brice, Kim Wals, Nicholas J. Matheson, Robin Antrobus, Sonja Ludwig, Theresa L. Whiteside, Cindy Sander, Ahmad A. Tarhini, John M. Kirkwood, Paul J. Lehner, Wei Guo, Hallgeir Rui, Andy J. Minn, Constantinos Koumenis, J. Alan Diehl, Serge Y. Fuchs

Cancer Cell. Author manuscript; available in PMC 2020 Jan 14.

Published in final edited form as: Cancer Cell. 2019 Jan 14; 35(1): 33–45.e6. doi: 10.1016/j.ccell.2018.12.001

PMCID:: PMC6336114

Abstract Article PDF–2.6M

Select item 614669410.

25-Hydroxycholesterol Production by the Cholesterol-25-Hydroxylase Interferon-Stimulated Gene Restricts Mammalian Reovirus Infection

Alexandra Doms, Tatiana Sanabria, Jeanne N. Hansen, Nihal Altan-Bonnet, Geoffrey H. Holm

J Virol. 2018 Sep 15; 92(18): e01047-18. Prepublished online 2018 Jun 27. Published online 2018 Aug 29. doi: 10.1128/JVI.01047-18

PMCID:: PMC6146694

Abstract Article PDF–1.6M

Select item 537173011.

Systematic protein–protein interaction mapping for clinically relevant human GPCRs

Kate Sokolina, Saranya Kittanakom, Jamie Snider, Max Kotlyar, Pascal Maurice, Jorge Gandía, Abla Benleulmi‐Chaachoua, Kenjiro Tadagaki, Atsuro Oishi, Victoria Wong, Ramy H Malty, Viktor Deineko, Hiroyuki Aoki, Shahreen Amin, Zhong Yao, Xavier Morató, David Otasek, Hiroyuki Kobayashi, Javier Menendez, Daniel Auerbach, Stephane Angers, Natasa Pržulj, Michel Bouvier, Mohan Babu, Francisco Ciruela, Ralf Jockers, Igor Jurisica, Igor Stagljar

Mol Syst Biol. 2017 Mar; 13(3): 918. Published online 2017 Mar 15. doi: 10.15252/msb.20167430

PMCID:: PMC5371730

Abstract Article PDF–4.1M

Select item 513366312.

Mass spectrometry profiling of oxysterols in human sperm identifies 25-hydroxycholesterol as a marker of sperm function

Chiara Zerbinati, Luisa Caponecchia, Rosa Puca, Marco Ciacciarelli, Pietro Salacone, Annalisa Sebastianelli, Antonio Pastore, Giovanni Palleschi, Vincenzo Petrozza, Natale Porta, Rocco Rago, Antonio Carbone, Luigi Iuliano

Redox Biol. 2017 Apr; 11: 111–117. Published online 2016 Nov 22. doi: 10.1016/j.redox.2016.11.008

PMCID:: PMC5133663

Abstract Article PDF–702K

Select item 509216013.

Analysis of CH25H in multiple sclerosis and neuromyelitis optica

Amanda L Forwell, Cecily Q Bernales, Jay P Ross, Irene M Yee, Mary Encarnacion, Joshua D Lee, A Dessa Sadovnick, Anthony L Traboulsee, Carles Vilariño-Güell

J Neuroimmunol. Author manuscript; available in PMC 2016 Nov 2.

Published in final edited form as: J Neuroimmunol. 2016 Feb 15; 291: 70–72. Published online 2015 Dec 31. doi: 10.1016/j.jneuroim.2015.12.014

PMCID:: PMC5092160

Article PDF–189K

Select item 460681114.

The HIV matrix protein p17 induces hepatic lipid accumulation via modulation of nuclear receptor transcriptoma

Barbara Renga, Daniela Francisci, Adriana Carino, Silvia Marchianò, Sabrina Cipriani, Maria Chiara Monti, Rachele Del Sordo, Elisabetta Schiaroli, Eleonora Distrutti, Franco Baldelli, Stefano Fiorucci

Sci Rep. 2015; 5: 15403. Published online 2015 Oct 15. doi: 10.1038/srep15403

PMCID:: PMC4606811

Abstract Article PDF–1.3M

Select item 446847915.

Identification of Cholesterol 25-Hydroxylase as a Novel Host Restriction Factor and a Part of the Primary Innate Immune Responses against Hepatitis C Virus Infection

Yu Xiang, Jing-Jie Tang, Wanyin Tao, Xuezhi Cao, Bao-Liang Song, Jin Zhong

J Virol. 2015 Jul 1; 89(13): 6805–6816. Published online 2015 Apr 22. doi: 10.1128/JVI.00587-15

PMCID:: PMC4468479

Abstract Article PDF–2.6M

Select item 405025016.

Differential effects of Tat proteins derived from HIV-1 subtypes B and recombinant CRF02_AG on human brain microvascular endothelial cells: implications for blood–brain barrier dysfunction

Shawna M Woollard, Biju Bhargavan, Fang Yu, Georgette D Kanmogne

J Cereb Blood Flow Metab. 2014 Jun; 34(6): 1047–1059. Published online 2014 Mar 26. doi: 10.1038/jcbfm.2014.54

PMCID:: PMC4050250

Abstract Article PDF–932K

Select item 317805917.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 302569518.

The Association of Genome-Wide Variation with the Risk of Incident Heart Failure in Adults of European and African Ancestry: A Prospective Meta-Analysis from the CHARGE Consortium

Nicholas L. Smith, Janine F. Felix, Alanna C. Morrison, Serkalem Demissie, Nicole L. Glazer, Laura R. Loehr, L. Adrienne Cupples, Abbas Dehghan, Thomas Lumley, Wayne D. Rosamond, Wolfgang Lieb, Fernando Rivadeneira, Joshua C. Bis, Aaron R. Folsom, Emelia Benjamin, Yurii S. Aulchenko, Talin Haritunians, David Couper, Joanne Murabito, Ying A. Wang, Bruno H. Stricker, John S. Gottdiener, Patricia P. Chang, Thomas J. Wang, Kenneth M. Rice, Albert Hofman, Susan R. Heckbert, Ervin R. Fox, Christopher J. O’Donnell, Andre G. Uitterlinden, Jerome I. Rotter, James T. Willerson, Daniel Levy, Cornelia M. van Duijn, Bruce M. Psaty, Jacqueline C. M. Witteman, Eric Boerwinkle, Ramachandran S. Vasan

Circ Cardiovasc Genet. Author manuscript; available in PMC 2011 Jun 1.

Published in final edited form as: Circ Cardiovasc Genet. 2010 Jun 1; 3(3): 256–266. Published online 2010 May 5. doi: 10.1161/CIRCGENETICS.109.895763

PMCID:: PMC3025695

Abstract Article PDF–602K

Select item 299689919.

Cholesterol 25-hydroxylase production by dendritic cells and macrophages is regulated by type I interferons

Kiwon Park, Alan L. Scott

J Leukoc Biol. 2010 Dec; 88(6): 1081–1087. doi: 10.1189/jlb.0610318

PMCID:: PMC2996899

Abstract Article

Select item 299160920.

Identification of Genomic Predictors of Atrioventricular Conduction: Using Electronic Medical Records as a Tool for Genome Science

Joshua C. Denny, Marylyn D. Ritchie, Dana C. Crawford, Jonathan S. Schildcrout, Andrea H. Ramirez, Jill M. Pulley, Melissa A. Basford, Daniel R. Masys, Jonathan L. Haines, Dan M. Roden

Circulation. Author manuscript; available in PMC 2011 Nov 16.

Published in final edited form as: Circulation. 2010 Nov 16; 122(20): 2016–2021. Published online 2010 Nov 1. doi: 10.1161/CIRCULATIONAHA.110.948828

PMCID:: PMC2991609

Abstract Article PDF–361K

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