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Select item 108764401.

IFT88 maintains sensory function by localising signalling proteins along Drosophila cilia

Sascha Werner, Pilar Okenve-Ramos, Philip Hehlert, Sihem Zitouni, Pranjali Priya, Susana Mendonça, Anje Sporbert, Christian Spalthoff, Martin C Göpfert, Swadhin Chandra Jana, Mónica Bettencourt-Dias

Life Sci Alliance. 2024 May; 7(5): e202302289. Published online 2024 Feb 19. doi: 10.26508/lsa.202302289

PMCID:: PMC10876440

Abstract Article PDF–2.8M

Select item 103486742.

Structural basis for the ubiquitination of G protein βγ subunits by KCTD5/Cullin3 E3 ligase

Wentong Jiang, Wei Wang, Yinfei Kong, Sanduo Zheng

Sci Adv. 2023 Jul; 9(28): eadg8369. Published online 2023 Jul 14. doi: 10.1126/sciadv.adg8369

PMCID:: PMC10348674

Abstract Article PDF–2.3M

Select item 92877403.

Pre-adult exposure to three heavy metals leads to changes in the head transcriptome of adult flies

Kenton R Felmlee, Stuart J Macdonald, Elizabeth R Everman

MicroPubl Biol. 2022; 2022: 10.17912/micropub.biology.000591. Published online 2022 Jul 2. doi: 10.17912/micropub.biology.000591

PMCID:: PMC9287740

Abstract Article PDF–1.0M

Select item 87105504.

cGMP signaling pathway that modulates NF-κB activation in innate immune responses

Hirotaka Kanoh, Shinzo Iwashita, Takayuki Kuraishi, Akira Goto, Naoyuki Fuse, Haruna Ueno, Mariko Nimura, Tomohito Oyama, Chang Tang, Ryo Watanabe, Aki Hori, Yoshiki Momiuchi, Hiroki Ishikawa, Hiroaki Suzuki, Kumiko Nabe, Takeshi Takagaki, Masataka Fukuzaki, Li-Li Tong, Sinya Yamada, Yoshiteru Oshima, Toshiro Aigaki, Julian A.T. Dow, Shireen-Anne Davies, Shoichiro Kurata

iScience. 2021 Dec 17; 24(12): 103473. Published online 2021 Nov 18. doi: 10.1016/j.isci.2021.103473

PMCID:: PMC8710550

Abstract Article PDF–2.6M

Select item 86644865.

Genome-wide phenotypic RNAi screen in the Drosophila wing: phenotypic description of functional classes

Ana López-Varea, Patricia Vega-Cuesta, Ana Ruiz-Gómez, Cristina M Ostalé, Cristina Molnar, Covadonga F Hevia, Mercedes Martín, Maria F Organista, Jesus de Celis, Joaquín Culí, Nuria Esteban, Jose F de Celis

G3 (Bethesda) 2021 Dec; 11(12): jkab349. Published online 2021 Oct 2. doi: 10.1093/g3journal/jkab349

PMCID:: PMC8664486

Abstract Article PDF–3.1M

Select item 69990896.

A Receptor Guanylate Cyclase, Gyc76C, Mediates Humoral, and Cellular Responses in Distinct Ways in Drosophila Immunity

Shinzo Iwashita, Hiroaki Suzuki, Akira Goto, Tomohito Oyama, Hirotaka Kanoh, Takayuki Kuraishi, Naoyuki Fuse, Tamaki Yano, Yoshiteru Oshima, Julian A. T. Dow, Shireen-Anne Davies, Shoichiro Kurata

Front Immunol. 2020; 11: 35. Published online 2020 Jan 28. doi: 10.3389/fimmu.2020.00035

PMCID:: PMC6999089

Abstract Article PDF–1.2M

Select item 69615787.

CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans

Ping Wei, Wen Xue, Yun Zhao, Guang Ning, Jiwu Wang

Genome Res. 2020 Jan; 30(1): 95–106. doi: 10.1101/gr.250811.119

PMCID:: PMC6961578

Abstract Article PDF–3.6M

Select item 67297158.

The Drosophila Receptor Guanylyl Cyclase Gyc76C Is Required for Semaphorin-1a-Plexin A-Mediated Axonal Repulsion

Joseph C. Ayoob, Hung-Hsiang Yu, Jonathan R. Terman, Alex L. Kolodkin

J Neurosci. 2004 Jul 28; 24(30): 6639–6649. doi: 10.1523/JNEUROSCI.1104-04.2004

PMCID:: PMC6729715

Abstract Article PDF–997K

Select item 61905939.

Immunity in Drosophila melanogaster — from microbial recognition to whole- organism physiology

Nicolas Buchon, Neal Silverman, Sara Cherry

Nat Rev Immunol. Author manuscript; available in PMC 2018 Oct 16.

Published in final edited form as: Nat Rev Immunol. 2014 Dec; 14(12): 796–810. doi: 10.1038/nri3763

PMCID:: PMC6190593

Abstract Article PDF–1.0M

Select item 593136910.

A Whole Animal Platform to Advance A Clinical Kinase Inhibitor Into New Disease Space

Masahiro Sonoshita, Alex P. Scopton, Peter M-U. Ung, Matthew A. Murray, Lisa Silber, Andres Y. Maldonado, Alexander Real, Avner Schlessinger, Ross L. Cagan, Arvin C. Dar

Nat Chem Biol. Author manuscript; available in PMC 2018 Jul 22.

Published in final edited form as: Nat Chem Biol. 2018 Mar; 14(3): 291–298. Published online 2018 Jan 22. doi: 10.1038/nchembio.2556

PMCID:: PMC5931369

Abstract Article PDF–2.9M

Select item 570780511.

Landscape and evolution of tissue-specific alternative polyadenylation across Drosophila species

Piero Sanfilippo, Jiayu Wen, Eric C. Lai

Genome Biol. 2017; 18: 229. Published online 2017 Nov 30. doi: 10.1186/s13059-017-1358-0

PMCID:: PMC5707805

Abstract Article PDF–3.2M

Select item 568900212.

Transcription elongation rate has a tissue-specific impact on alternative cleavage and polyadenylation in Drosophila melanogaster

Xiaochuan Liu, Jaime Freitas, Dinghai Zheng, Marta S. Oliveira, Mainul Hoque, Torcato Martins, Telmo Henriques, Bin Tian, Alexandra Moreira

RNA. 2017 Dec; 23(12): 1807–1816. doi: 10.1261/rna.062661.117

PMCID:: PMC5689002

Abstract Article PDF–4.0M

Select item 502801713.

Receptor-Type Guanylyl Cyclase at 76C (Gyc76C) Regulates De Novo Lumen Formation during Drosophila Tracheal Development

Monn Monn Myat, Unisha Patel

PLoS One. 2016; 11(9): e0161865. Published online 2016 Sep 19. doi: 10.1371/journal.pone.0161865

PMCID:: PMC5028017

Abstract Article PDF–2.6M

Select item 492804714.

Cold acclimation wholly reorganizes the Drosophila melanogaster transcriptome and metabolome

Heath A. MacMillan, Jose M. Knee, Alice B. Dennis, Hiroko Udaka, Katie E. Marshall, Thomas J. S. Merritt, Brent J. Sinclair

Sci Rep. 2016; 6: 28999. Published online 2016 Jun 30. doi: 10.1038/srep28999

PMCID:: PMC4928047

Abstract Article PDF–3.1M

Select item 459508615.

The Gyc76C Receptor Guanylyl Cyclase and the Foraging cGMP-Dependent Kinase Regulate Extracellular Matrix Organization and BMP Signaling in the Developing Wing of Drosophila melanogaster

Justin Schleede, Seth S. Blair

PLoS Genet. 2015 Oct; 11(10): e1005576. Published online 2015 Oct 6. doi: 10.1371/journal.pgen.1005576

PMCID:: PMC4595086

Abstract Article PDF–22M

Select item 457069716.

Putative synaptic genes defined from a Drosophila whole body developmental transcriptome by a machine learning approach

Flavio Pazos Obregón, Cecilia Papalardo, Sebastián Castro, Gustavo Guerberoff, Rafael Cantera

BMC Genomics. 2015; 16(1): 694. Published online 2015 Sep 15. doi: 10.1186/s12864-015-1888-3

PMCID:: PMC4570697

Abstract Article PDF–2.0M

Select item 452833017.

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders

Madeline A. Crosby, L. Sian Gramates, Gilberto dos Santos, Beverley B. Matthews, Susan E. St. Pierre, Pinglei Zhou, Andrew J. Schroeder, Kathleen Falls, David B. Emmert, Susan M. Russo, William M. Gelbart, the FlyBase Consortium

G3 (Bethesda) 2015 Aug; 5(8): 1737–1749. Published online 2015 Jun 24. doi: 10.1534/g3.115.018937

PMCID:: PMC4528330

Abstract Article PDF–2.2M

Select item 452832918.

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data

Beverley B. Matthews, Gilberto dos Santos, Madeline A. Crosby, David B. Emmert, Susan E. St. Pierre, L. Sian Gramates, Pinglei Zhou, Andrew J. Schroeder, Kathleen Falls, Victor Strelets, Susan M. Russo, William M. Gelbart, the FlyBase Consortium

G3 (Bethesda) 2015 Aug; 5(8): 1721–1736. Published online 2015 Jun 24. doi: 10.1534/g3.115.018929