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Items: 1 to 20 of 50

1.
Large-language models facilitate discovery of the molecular signatures regulating sleep and activity
Di Peng, Liubin Zheng, Dan Liu, Cheng Han, Xin Wang, Yan Yang, Li Song, Miaoying Zhao, Yanfeng Wei, Jiayi Li, Xiaoxue Ye, Yuxiang Wei, Zihao Feng, Xinhe Huang, Miaomiao Chen, Yujie Gou, Yu Xue, Luoying Zhang
Nat Commun. 2024; 15: 3685. Published online 2024 May 1. doi: 10.1038/s41467-024-48005-w
PMCID:
PMC11063160
AbstractArticlePDF–2.7M
2.
Activation of Ca2+ phosphatase Calcineurin regulates Parkin translocation to mitochondria and mitophagy in flies
Elena Marchesan, Alice Nardin, Sofia Mauri, Greta Bernardo, Vivek Chander, Simone Di Paola, Monica Chinellato, Sophia von Stockum, Joy Chakraborty, Stephanie Herkenne, Valentina Basso, Emilie Schrepfer, Oriano Marin, Laura Cendron, Diego L. Medina, Luca Scorrano, Elena Ziviani
Cell Death Differ. 2024 Feb; 31(2): 217–238. Published online 2024 Jan 18. doi: 10.1038/s41418-023-01251-9
PMCID:
PMC10850161
AbstractArticlePDF–19M
3.
Systematic analysis of the Frazzled receptor interactome establishes previously unreported regulators of axon guidance
Yixin Zang, Greg J. Bashaw
Development. 2023 Aug 1; 150(15): dev201636. Published online 2023 Aug 1. doi: 10.1242/dev.201636
PMCID:
PMC10445734
AbstractArticle
4.
The calcineurin regulator Sarah enables distinct forms of homeostatic plasticity at the Drosophila neuromuscular junction
Noah S. Armstrong, C. Andrew Frank
Front Synaptic Neurosci. 2022; 14: 1033743. Published online 2023 Jan 4. doi: 10.3389/fnsyn.2022.1033743
PMCID:
PMC9846150
AbstractArticlePDF–9.4M
5.
CBP-Mediated Acetylation of Importin α Mediates Calcium-Dependent Nucleocytoplasmic Transport of Selective Proteins in Drosophila Neurons
Jae Ho Cho, Min Gu Jo, Eun Seon Kim, Na Yoon Lee, Soon Ha Kim, Chang Geon Chung, Jeong Hyang Park, Sung Bae Lee
Mol Cells. 2022 Nov 30; 45(11): 855–867. Published online 2022 Sep 28. doi: 10.14348/molcells.2022.0104
PMCID:
PMC9676984
AbstractArticlePDF–2.2M
6.
Identification of Therapeutic Targets for Amyotrophic Lateral Sclerosis Using PandaOmics – An AI-Enabled Biological Target Discovery Platform
Frank W. Pun, Bonnie Hei Man Liu, Xi Long, Hoi Wing Leung, Geoffrey Ho Duen Leung, Quinlan T. Mewborne, Junli Gao, Anastasia Shneyderman, Ivan V. Ozerov, Ju Wang, Feng Ren, Alexander Aliper, Evelyne Bischof, Evgeny Izumchenko, Xiaoming Guan, Ke Zhang, Bai Lu, Jeffrey D. Rothstein, Merit E. Cudkowicz, Alex Zhavoronkov
Front Aging Neurosci. 2022; 14: 914017. Published online 2022 Jun 28. doi: 10.3389/fnagi.2022.914017
PMCID:
PMC9273868
AbstractArticlePDF–3.6M
7.
Transgenic Drosophila lines for LexA-dependent gene and growth regulation
Kathleen R Chang, Deborah D Tsao, Celine Bennett, Elaine Wang, Jax F Floyd, Ashley S Y Tay, Emily Greenwald, Ella S Kim, Catherine Griffin, Elizabeth Morse, Townley Chisholm, Anne E Rankin, Luis Alberto Baena-Lopez, Nicole Lantz, Elizabeth Fox, Lutz Kockel, Seung K Kim, Sangbin Park
G3 (Bethesda) 2022 Mar; 12(3): jkac018. Published online 2022 Jan 19. doi: 10.1093/g3journal/jkac018
PMCID:
PMC8895989
AbstractArticlePDF–1.0M
8.
Genome-wide phenotypic RNAi screen in the Drosophila wing: phenotypic description of functional classes
Ana López-Varea, Patricia Vega-Cuesta, Ana Ruiz-Gómez, Cristina M Ostalé, Cristina Molnar, Covadonga F Hevia, Mercedes Martín, Maria F Organista, Jesus de Celis, Joaquín Culí, Nuria Esteban, Jose F de Celis
G3 (Bethesda) 2021 Dec; 11(12): jkab349. Published online 2021 Oct 2. doi: 10.1093/g3journal/jkab349
PMCID:
PMC8664486
AbstractArticlePDF–3.1M
9.
Cytosolic calcium regulates cytoplasmic accumulation of TDP-43 through Calpain-A and Importin α3
Jeong Hyang Park, Chang Geon Chung, Sung Soon Park, Davin Lee, Kyung Min Kim, Yeonjin Jeong, Eun Seon Kim, Jae Ho Cho, Yu-Mi Jeon, C-K James Shen, Hyung-Jun Kim, Daehee Hwang, Sung Bae Lee
eLife. 2020; 9: e60132. Published online 2020 Dec 11. doi: 10.7554/eLife.60132
PMCID:
PMC7748415
AbstractArticlePDF–6.2M
10.
Overlapping activities of ELAV/Hu family RNA binding proteins specify the extended neuronal 3’ UTR landscape in Drosophila
Lu Wei, Seungjae Lee, Sonali Majumdar, Binglong Zhang, Piero Sanfilippo, Brian Joseph, Pedro Miura, Matthias Soller, Eric C. Lai
Mol Cell. Author manuscript; available in PMC 2021 Oct 1.
Published in final edited form as: Mol Cell. 2020 Oct 1; 80(1): 140–155.e6. doi: 10.1016/j.molcel.2020.09.007
PMCID:
PMC7546445
AbstractArticlePDF–3.8M
11.
Adar RNA editing-dependent and -independent effects are required for brain and innate immune functions in Drosophila
Patricia Deng, Anzer Khan, Dionna Jacobson, Nagraj Sambrani, Leeanne McGurk, Xianghua Li, Aswathy Jayasree, Jan Hejatko, Galit Shohat-Ophir, Mary A. O’Connell, Jin Billy Li, Liam P. Keegan
Nat Commun. 2020; 11: 1580. Published online 2020 Mar 27. doi: 10.1038/s41467-020-15435-1
PMCID:
PMC7101428
AbstractArticlePDF–1.6M
12.
Calcineurin and Its Regulator Sra/DSCR1 Are Essential for Sleep in Drosophila
Yasuhiro Nakai, Junjiro Horiuchi, Manabu Tsuda, Satomi Takeo, Shin Akahori, Takashi Matsuo, Kazuhiko Kume, Toshiro Aigaki
J Neurosci. 2011 Sep 7; 31(36): 12759–12766. doi: 10.1523/JNEUROSCI.1337-11.2011
PMCID:
PMC6623415
AbstractArticlePDF–1.8M
13.
Pan-Neuronal Knockdown of Calcineurin Reduces Sleep in the Fruit Fly, Drosophila melanogaster
Jun Tomita, Madoka Mitsuyoshi, Taro Ueno, Yoshinori Aso, Hiromu Tanimoto, Yasuhiro Nakai, Toshiro Aigaki, Shoen Kume, Kazuhiko Kume
J Neurosci. 2011 Sep 14; 31(37): 13137–13146. doi: 10.1523/JNEUROSCI.5860-10.2011
PMCID:
PMC6623252
AbstractArticlePDF–3.3M
14.
Glial Ca2+signaling links endocytosis to K+ buffering around neuronal somas to regulate excitability
Shirley Weiss, Jan E Melom, Kiel G Ormerod, Yao V Zhang, J Troy Littleton
eLife. 2019; 8: e44186. Published online 2019 Apr 26. doi: 10.7554/eLife.44186
PMCID:
PMC6510531
AbstractArticlePDF–5.3M
15.
High-Amplitude Circadian Rhythms in Drosophila Driven by Calcineurin-Mediated Post-translational Control of sarah
Sin Ho Kweon, Jongbin Lee, Chunghun Lim, Joonho Choe
Genetics. 2018 Jul; 209(3): 815–828. Published online 2018 May 3. doi: 10.1534/genetics.118.300808
PMCID:
PMC6028259
AbstractArticlePDF–2.1M
16.
An RNAi-mediated screen identifies novel targets for next-generation antiepileptic drugs based on increased expression of the homeostatic regulator pumilio
Wei-Hsiang Lin, Miaomiao He, Yuen Ngan Fan, Richard A. Baines
J Neurogenet. 2018; 32(2): 106–117. Published online 2018 May 2. doi: 10.1080/01677063.2018.1465570
PMCID:
PMC5989157
AbstractArticlePDF–1.5M
17.
Landscape and evolution of tissue-specific alternative polyadenylation across Drosophila species
Piero Sanfilippo, Jiayu Wen, Eric C. Lai
Genome Biol. 2017; 18: 229. Published online 2017 Nov 30. doi: 10.1186/s13059-017-1358-0
PMCID:
PMC5707805
AbstractArticlePDF–3.2M
18.
Transcription elongation rate has a tissue-specific impact on alternative cleavage and polyadenylation in Drosophila melanogaster
Xiaochuan Liu, Jaime Freitas, Dinghai Zheng, Marta S. Oliveira, Mainul Hoque, Torcato Martins, Telmo Henriques, Bin Tian, Alexandra Moreira
RNA. 2017 Dec; 23(12): 1807–1816. doi: 10.1261/rna.062661.117
PMCID:
PMC5689002
AbstractArticlePDF–4.0M
19.
Reduced Cardiac Calcineurin Expression Mimics Long-Term Hypoxia-Induced Heart Defects in Drosophila
Rachel Zarndt, Stanley M. Walls, Karen Ocorr, Rolf Bodmer
Circ Cardiovasc Genet. Author manuscript; available in PMC 2018 Oct 1.
Published in final edited form as: Circ Cardiovasc Genet. 2017 Oct; 10(5): e001706. doi: 10.1161/CIRCGENETICS.117.001706
PMCID:
PMC5669044
AbstractArticlePDF–1.4M
20.
High-content behavioral profiling reveals neuronal genetic network modulating Drosophila larval locomotor program
Boanerges Aleman-Meza, Mario Loeza-Cabrera, Omar Peña-Ramos, Michael Stern, Weiwei Zhong
BMC Genet. 2017; 18: 40. Published online 2017 May 12. doi: 10.1186/s12863-017-0513-7
PMCID:
PMC5429570
AbstractArticlePDF–919K

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