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Select item 75814291.

Patient-specific genomics and cross-species functional analysis implicate LRP2 in hypoplastic left heart syndrome

Jeanne L Theis, Georg Vogler, Maria A Missinato, Xing Li, Tanja Nielsen, Xin-Xin I Zeng, Almudena Martinez-Fernandez, Stanley M Walls, Anaïs Kervadec, James N Kezos, Katja Birker, Jared M Evans, Megan M O'Byrne, Zachary C Fogarty, André Terzic, Paul Grossfeld, Karen Ocorr, Timothy J Nelson, Timothy M Olson, Alexandre R Colas, Rolf Bodmer

eLife. 2020; 9: e59554. Published online 2020 Oct 2. doi: 10.7554/eLife.59554

PMCID:: PMC7581429

Abstract Article PDF–3.4M

Select item 65065392.

Tissue-specific (ts)CRISPR as an efficient strategy for in vivo screening in Drosophila

Hagar Meltzer, Efrat Marom, Idan Alyagor, Oded Mayseless, Victoria Berkun, Netta Segal-Gilboa, Tamar Unger, David Luginbuhl, Oren Schuldiner

Nat Commun. 2019; 10: 2113. Published online 2019 May 8. doi: 10.1038/s41467-019-10140-0

PMCID:: PMC6506539

Abstract Article PDF–6.5M

Select item 57078053.

Landscape and evolution of tissue-specific alternative polyadenylation across Drosophila species

Piero Sanfilippo, Jiayu Wen, Eric C. Lai

Genome Biol. 2017; 18: 229. Published online 2017 Nov 30. doi: 10.1186/s13059-017-1358-0

PMCID:: PMC5707805

Abstract Article PDF–3.2M

Select item 56890024.

Transcription elongation rate has a tissue-specific impact on alternative cleavage and polyadenylation in Drosophila melanogaster

Xiaochuan Liu, Jaime Freitas, Dinghai Zheng, Marta S. Oliveira, Mainul Hoque, Torcato Martins, Telmo Henriques, Bin Tian, Alexandra Moreira

RNA. 2017 Dec; 23(12): 1807–1816. doi: 10.1261/rna.062661.117

PMCID:: PMC5689002

Abstract Article PDF–4.0M

Select item 53120045.

Seizure control through genetic and pharmacological manipulation of Pumilio in Drosophila: a key component of neuronal homeostasis

Wei-Hsiang Lin, Carlo N. G. Giachello, Richard A. Baines

Dis Model Mech. 2017 Feb 1; 10(2): 141–150. doi: 10.1242/dmm.027045

PMCID:: PMC5312004

Abstract Article

Select item 45945436.

The effect of neurospecific knockdown of candidate genes for locomotor behavior and sound production in Drosophila melanogaster

Sergey A Fedotov, Julia V Bragina, Natalia G Besedina, Larisa V Danilenkova, Elena A Kamysheva, Anna A Panova, Nikolai G Kamyshev

Fly (Austin) 2014 Jul; 8(3): 176–187. Published online 2014 Dec 13. doi: 10.4161/19336934.2014.983389

PMCID:: PMC4594543

Abstract Article PDF–1.1M

Select item 45283307.

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders

Madeline A. Crosby, L. Sian Gramates, Gilberto dos Santos, Beverley B. Matthews, Susan E. St. Pierre, Pinglei Zhou, Andrew J. Schroeder, Kathleen Falls, David B. Emmert, Susan M. Russo, William M. Gelbart, the FlyBase Consortium

G3 (Bethesda) 2015 Aug; 5(8): 1737–1749. Published online 2015 Jun 24. doi: 10.1534/g3.115.018937

PMCID:: PMC4528330

Abstract Article PDF–2.2M

Select item 45283298.

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data

Beverley B. Matthews, Gilberto dos Santos, Madeline A. Crosby, David B. Emmert, Susan E. St. Pierre, L. Sian Gramates, Pinglei Zhou, Andrew J. Schroeder, Kathleen Falls, Victor Strelets, Susan M. Russo, William M. Gelbart, the FlyBase Consortium

G3 (Bethesda) 2015 Aug; 5(8): 1721–1736. Published online 2015 Jun 24. doi: 10.1534/g3.115.018929

PMCID:: PMC4528329

Abstract Article PDF–4.9M

Select item 44036679.

Transcription Factor Networks in Drosophila melanogaster

David Y. Rhee, Dong-Yeon Cho, Bo Zhai, Matthew Slattery, Lijia Ma, Julian Mintseris, Christina Y. Wong, Kevin P. White, Susan E. Celniker, Teresa M. Przytycka, Steven P. Gygi, Robert A. Obar, Spyros Artavanis-Tsakonas

Cell Rep. Author manuscript; available in PMC 2015 Apr 20.

Published in final edited form as: Cell Rep. 2014 Sep 25; 8(6): 2031–2043. Published online 2014 Sep 18. doi: 10.1016/j.celrep.2014.08.038

PMCID:: PMC4403667

Abstract Article PDF–1.3M

Select item 439805010.

The Genetic Basis for Variation in Olfactory Behavior in Drosophila melanogaster

Gunjan H. Arya, Michael M. Magwire, Wen Huang, Yazmin L. Serrano-Negron, Trudy F.C. Mackay, Robert R.H. Anholt

Chem Senses. 2015 May; 40(4): 233–243. Published online 2015 Feb 15. doi: 10.1093/chemse/bjv001

PMCID:: PMC4398050

Abstract Article PDF–8.9M

Select item 435288711.

The Release 6 reference sequence of the Drosophila melanogaster genome

Roger A. Hoskins, Joseph W. Carlson, Kenneth H. Wan, Soo Park, Ivonne Mendez, Samuel E. Galle, Benjamin W. Booth, Barret D. Pfeiffer, Reed A. George, Robert Svirskas, Martin Krzywinski, Jacqueline Schein, Maria Carmela Accardo, Elisabetta Damia, Giovanni Messina, María Méndez-Lago, Beatriz de Pablos, Olga V. Demakova, Evgeniya N. Andreyeva, Lidiya V. Boldyreva, Marco Marra, A. Bernardo Carvalho, Patrizio Dimitri, Alfredo Villasante, Igor F. Zhimulev, Gerald M. Rubin, Gary H. Karpen, Susan E. Celniker

Genome Res. 2015 Mar; 25(3): 445–458. doi: 10.1101/gr.185579.114

PMCID:: PMC4352887

Abstract Article PDF–1022K

Select item 384508712.

Stable pausing by RNA polymerase II provides an opportunity to target and integrate regulatory signals

Telmo Henriques, Daniel A. Gilchrist, Sergei Nechaev, Michael Bern, Ginger W. Muse, Adam Burkholder, David C. Fargo, Karen Adelman

Mol Cell. Author manuscript; available in PMC 2014 Nov 21.

Published in final edited form as: Mol Cell. 2013 Nov 21; 52(4): 10.1016/j.molcel.2013.10.001. Published online 2013 Oct 31. doi: 10.1016/j.molcel.2013.10.001

PMCID:: PMC3845087

Abstract Article PDF–4.4M

Select item 369674613.

Landscape of protein–protein interactions in Drosophila immune deficiency signaling during bacterial challenge

Hidehiro Fukuyama, Yann Verdier, Yongsheng Guan, Chieko Makino-Okamura, Victoria Shilova, Xi Liu, Elie Maksoud, Jun Matsubayashi, Iman Haddad, Kerstin Spirohn, Kenichiro Ono, Charles Hetru, Jean Rossier, Trey Ideker, Michael Boutros, Joëlle Vinh, Jules A. Hoffmann

Proc Natl Acad Sci U S A. 2013 Jun 25; 110(26): 10717–10722. Published online 2013 Jun 7. doi: 10.1073/pnas.1304380110

PMCID:: PMC3696746

Abstract Article PDF–903K

Select item 353067714.

High-fidelity promoter profiling reveals widespread alternative promoter usage and transposon-driven developmental gene expression

Philippe Batut, Alexander Dobin, Charles Plessy, Piero Carninci, Thomas R. Gingeras

Genome Res. 2013 Jan; 23(1): 169–180. doi: 10.1101/gr.139618.112

PMCID:: PMC3530677

Abstract Article PDF–1.5M

Select item 350471715.

Conservation of caspase substrates across metazoans suggests hierarchical importance of signaling pathways over specific targets and cleavage site motifs in apoptosis

E D Crawford, J E Seaman, A E Barber, II, D C David, P C Babbitt, A L Burlingame, J A Wells

Cell Death Differ. 2012 Dec; 19(12): 2040–2048. Published online 2012 Aug 24. doi: 10.1038/cdd.2012.99

PMCID:: PMC3504717

Abstract Article PDF–932K

Select item 346946716.

The Many Landscapes of Recombination in Drosophila melanogaster

Josep M. Comeron, Ramesh Ratnappan, Samuel Bailin

PLoS Genet. 2012 Oct; 8(10): e1002905. Published online 2012 Oct 11. doi: 10.1371/journal.pgen.1002905

PMCID:: PMC3469467

Abstract Article PDF–1.6M

Select item 331904817.

A Protein Complex Network of Drosophila melanogaster

K. G. Guruharsha, J. -F. Rual, B. Zhai, J. Mintseris, P. Vaidya, N. Vaidya, C. Beekman, C. Wong, D. Y. Rhee, O. Cenaj, E. McKillip, S. Shah, M. Stapleton, K. H. Wan, C. Yu, B. Parsa, J. W. Carlson, X. Chen, B. Kapadia, K. VijayRaghavan, S. P. Gygi, S. E. Celniker, R. A. Obar, S. Artavanis-Tsakonas

Cell. Author manuscript; available in PMC 2012 Oct 28.

Published in final edited form as: Cell. 2011 Oct 28; 147(3): 690–703. doi: 10.1016/j.cell.2011.08.047

PMCID:: PMC3319048

Abstract Article PDF–3.2M

Select item 330382518.

Genome Features of “Dark-Fly”, a Drosophila Line Reared Long-Term in a Dark Environment

Minako Izutsu, Jun Zhou, Yuzo Sugiyama, Osamu Nishimura, Tomoyuki Aizu, Atsushi Toyoda, Asao Fujiyama, Kiyokazu Agata, Naoyuki Fuse

PLoS One. 2012; 7(3): e33288. Published online 2012 Mar 14. doi: 10.1371/journal.pone.0033288

PMCID:: PMC3303825

Abstract Article PDF–688K

Select item 304921519.

Polyglutamine Atrophin provokes neurodegeneration in Drosophila by repressing fat

Francesco Napoletano, Simona Occhi, Piera Calamita, Vera Volpi, Eric Blanc, Bernard Charroux, Julien Royet, Manolis Fanto

EMBO J. 2011 Mar 2; 30(5): 945–958. Published online 2011 Jan 28. doi: 10.1038/emboj.2011.1

PMCID:: PMC3049215

Abstract Article PDF–3.2M

Select item 304044120.

A genome-wide Drosophila screen for heat nociception identifies α2δ3 as an evolutionary-conserved pain gene

G. Gregory Neely, Andreas Hess, Michael Costigan, Alex C. Keene, Spyros Goulas, Michiel Langeslag, Robert S Griffin, Inna Belfer, Feng Dai, Shad Smith, Luda Diatchenko, Vaijayanti Gupta, Cui-ping Xia, Sabina Amann, Silke Kreitz, Cornelia Heindl-Erdmann, Susanne Wolz, Cindy V. Ly, Suchir Arora, Rinku Sarangi, Debasis Dan, Maria Novatchkova, Mark Rosenzweig, Dustin Gibson, Darwin Truong, Daniel Schramek, Tamara Zoranovic, Shane J. F. Cronin, Belinda Angjeli, Kay Brune, Georg Dietzl, William Maixner, Arabella Meixner, Winston Thomas, J. Andrew Pospisilik, Mattias Alenius, Michaela Kress, Sai Subramaniam, Paul A. Garrity, Hugo J. Bellen, Clifford J. Woolf, Josef M. Penninger

Cell. Author manuscript; available in PMC 2011 Nov 12.

Published in final edited form as: Cell. 2010 Nov 12; 143(4): 628–638. doi: 10.1016/j.cell.2010.09.047

PMCID:: PMC3040441

Abstract Article PDF–2.0M

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