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Select item 115160521.

Platelet‐Derived Growth Factor C Facilitates Malignant Behavior of Pancreatic Ductal Adenocarcinoma by Regulating SREBP1 Mediated Lipid Metabolism

Yin‐Hao Shi, Zhi‐De Liu, Ming‐Jian Ma, Guang‐Yin Zhao, Ying‐Qin Zhu, Jie‐Qin Wang, Yang‐Yin‐Hui Yu, Xi‐Tai Huang, Jing‐Yuan Ye, Fu‐Xi Li, Xi‐Yu Wang, Qiong‐Cong Xu, Xiao‐Yu Yin

Adv Sci (Weinh) 2024 Oct; 11(40): 2407069. Published online 2024 Sep 3. doi: 10.1002/advs.202407069

PMCID:: PMC11516052

Abstract Article PDF–24M

Select item 108805552.

MicroRNA-29a inhibits glioblastoma stem cells and tumor growth by regulating the PDGF pathway

Yanzhi Yang, Samantha Dodbele, Thomas Park, Rainer Glass, Krishna Bhat, Erik P. Sulman, Ying Zhang, Roger Abounader

J Neurooncol. Author manuscript; available in PMC 2024 Feb 21.

Published in final edited form as: J Neurooncol. 2019 Oct; 145(1): 23–34. Published online 2019 Sep 3. doi: 10.1007/s11060-019-03275-z

PMCID:: PMC10880555

Abstract Article PDF–1.3M

Select item 100030653.

Impact of Acute High Glucose on Mitochondrial Function in a Model of Endothelial Cells: Role of PDGF-C

Adriana Grismaldo Rodríguez, Jairo Zamudio Rodríguez, Alfonso Barreto, Sandra Sanabria-Barrera, José Iglesias, Ludis Morales

Int J Mol Sci. 2023 Mar; 24(5): 4394. Published online 2023 Feb 23. doi: 10.3390/ijms24054394

PMCID:: PMC10003065

Abstract Article PDF–2.6M

Select item 91714114.

Physical and functional interactome atlas of human receptor tyrosine kinases

Kari Salokas, Xiaonan Liu, Tiina Öhman, Iftekhar Chowdhury, Lisa Gawriyski, Salla Keskitalo, Markku Varjosalo

EMBO Rep. 2022 Jun; 23(6): e54041. Published online 2022 Apr 5. doi: 10.15252/embr.202154041

PMCID:: PMC9171411

Abstract Article PDF–1.9M

Select item 91065775.

RNA N6-methyladenosine demethylase FTO promotes pancreatic cancer progression by inducing the autocrine activity of PDGFC in an m⁶A-YTHDF2-dependent manner

Zhen Tan, Si Shi, Jin Xu, Xiaomeng Liu, Yubin Lei, Bo Zhang, Jie Hua, Qingcai Meng, Wei Wang, Xianjun Yu, Chen Liang

Oncogene. 2022; 41(20): 2860–2872. Published online 2022 Apr 14. doi: 10.1038/s41388-022-02306-w

PMCID:: PMC9106577

Abstract Article PDF–5.5M

Select item 86337836.

Expression and function of PDGF-C in development and stem cells

Yi Tian, Ying Zhan, Qin Jiang, Weisi Lu, Xuri Li

Open Biol. 2021 Dec; 11(12): 210268. Published online December 1, 2021. doi: 10.1098/rsob.210268

PMCID:: PMC8633783

Abstract Article PDF–982K

Select item 81650307.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 79795408.

Cancer-associated fibroblast secretion of PDGFC promotes gastrointestinal stromal tumor growth and metastasis

Hyunho Yoon, Chih-Min Tang, Sudeep Banerjee, Mayra Yebra, Sangkyu Noh, Adam M. Burgoyne, Jorge De la Torre, Martina De Siena, Mengyuan Liu, Lillian R. Klug, Yoon Young Choi, Mojgan Hosseini, Antonio L. Delgado, Zhiyong Wang, Randall P. French, Andrew Lowy, Ronald P. DeMatteo, Michael C. Heinrich, Alfredo A. Molinolo, J. Silvio Gutkind, Olivier Harismendy, Jason K. Sicklick

Oncogene. 2021; 40(11): 1957–1973. Published online 2021 Feb 18. doi: 10.1038/s41388-021-01685-w

PMCID:: PMC7979540

Abstract Article PDF–7.2M

Select item 68729469.

An oncogenic activity of PDGF-C and its splice variant in human breast cancer

Alyssa Bottrell, Yong Hong Meng, Abdo J. Najy, Newton Hurst, Jr., Seongho Kim, Chong Jai Kim, Eun-Sook Kim, Aree Moon, Eun Joo Kim, So Yeon Park, Hyeong-Reh Choi Kim

Growth Factors. Author manuscript; available in PMC 2020 Sep 23.

Published in final edited form as: Growth Factors. 2019 Aug; 37(3-4): 131–145. Published online 2019 Sep 23. doi: 10.1080/08977194.2019.1662415

PMCID:: PMC6872946

Abstract Article PDF–1.5M

Select item 672814110.

PDGFs and their receptors

Andrius Kazlauskas

Gene. Author manuscript; available in PMC 2019 Sep 5.

Published in final edited form as: Gene. 2017 May 30; 614: 1–7. Published online 2017 Mar 4. doi: 10.1016/j.gene.2017.03.003

PMCID:: PMC6728141

Abstract Article PDF–715K

Select item 594574611.

The PDGF pathway in breast cancer is linked to tumour aggressiveness, triple-negative subtype and early recurrence

Sara Jansson, Kristina Aaltonen, Pär-Ola Bendahl, Anna-Karin Falck, Maria Karlsson, Kristian Pietras, Lisa Rydén

Breast Cancer Res Treat. 2018; 169(2): 231–241. Published online 2018 Jan 29. doi: 10.1007/s10549-018-4664-7

PMCID:: PMC5945746

Abstract Article PDF–1.2M

Select item 589672912.

Microenvironmental control of breast cancer subtype elicited by paracrine platelet derived growth factor-CC signaling

Pernilla Roswall, Matteo Bocci, Michael Bartoschek, Hong Li, Glen Kristiansen, Sara Jansson, Sophie Lehn, Jonas Sjölund, Steven Reid, Christer Larsson, Pontus Eriksson, Charlotte Anderberg, Eliane Cortez, Lao H Saal, Christina Orsmark-Pietras, Eugenia Cordero, B Kristian Haller, Jari Häkkinen, Ingrid JG Burvenich, Elgene Lim, Akira Orimo, Mattias Höglund, Lisa Rydén, Holger Moch, Andrew M Scott, Ulf Eriksson, Kristian Pietras

Nat Med. Author manuscript; available in PMC 2018 Sep 12.

Published in final edited form as: Nat Med. 2018 May; 24(4): 463–473. Published online 2018 Mar 12. doi: 10.1038/nm.4494

PMCID:: PMC5896729

Abstract Article PDF–2.7M

Select item 586483213.

An AP-MS- and BioID-compatible MAC-tag enables comprehensive mapping of protein interactions and subcellular localizations

Xiaonan Liu, Kari Salokas, Fitsum Tamene, Yaming Jiu, Rigbe G. Weldatsadik, Tiina Öhman, Markku Varjosalo

Nat Commun. 2018; 9: 1188. Published online 2018 Mar 22. doi: 10.1038/s41467-018-03523-2

PMCID:: PMC5864832

Abstract Article PDF–4.5M

Select item 553161114.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 537310115.

Genetic Variants in MicroRNA Biosynthesis Pathways and Binding Sites Modify Ovarian Cancer Risk, Survival, and Treatment Response

Dong Liang, Larissa Meyer, David W. Chang, Jie Lin, Xia Pu, Yuanqing Ye, Jian Gu, Xifeng Wu, Karen Lu

Cancer Res. Author manuscript; available in PMC 2017 Mar 30.

Published in final edited form as: Cancer Res. 2010 Dec 1; 70(23): 9765–9776. Published online 2010 Nov 30. doi: 10.1158/0008-5472.CAN-10-0130

PMCID:: PMC5373101

Abstract Article PDF–549K

Select item 498044816.

Endothelial PDGF-CC regulates angiogenesis-dependent thermogenesis in beige fat

Takahiro Seki, Kayoko Hosaka, Sharon Lim, Carina Fischer, Jennifer Honek, Yunlong Yang, Patrik Andersson, Masaki Nakamura, Erik Näslund, Seppo Ylä-Herttuala, Meili Sun, Hideki Iwamoto, Xuri Li, Yizhi Liu, Nilesh J. Samani, Yihai Cao

Nat Commun. 2016; 7: 12152. Published online 2016 Aug 5. doi: 10.1038/ncomms12152

PMCID:: PMC4980448

Abstract Article PDF–4.0M

Select item 483916817.

Presymptomatic activation of the PDGF-CC pathway accelerates onset of ALS neurodegeneration

Sebastian A. Lewandowski, Ingrid Nilsson, Linda Fredriksson, Peter Lönnerberg, Lars Muhl, Manuel Zeitelhofer, Milena Z. Adzemovic, Susanne Nichterwitz, Daniel A. Lawrence, Eva Hedlund, Ulf Eriksson

Acta Neuropathol. Author manuscript; available in PMC 2017 Mar 1.

Published in final edited form as: Acta Neuropathol. 2016 Mar; 131(3): 453–464. Published online 2015 Dec 19. doi: 10.1007/s00401-015-1520-2

PMCID:: PMC4839168

Abstract Article PDF–903K

Select item 481488718.

High glucose induces platelet‐derived growth factor‐C via carbohydrate response element‐binding protein in glomerular mesangial cells

Hiroya Kitsunai, Yuichi Makino, Hidemitsu Sakagami, Katsutoshi Mizumoto, Tsuyoshi Yanagimachi, Kuralay Atageldiyeva, Yasutaka Takeda, Yukihiro Fujita, Atsuko Abiko, Yumi Takiyama, Masakazu Haneda

Physiol Rep. 2016 Mar; 4(6): e12730. Published online 2016 Mar 31. doi: 10.14814/phy2.12730

PMCID:: PMC4814887

Abstract Article PDF–2.3M

Select item 461721119.

The BioPlex Network: A Systematic Exploration of the Human Interactome

Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2016 Jul 16.

Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043

PMCID:: PMC4617211

Abstract Article PDF–2.2M

Select item 426416820.

Post-Transcriptional Up-Regulation of PDGF-C by HuR in Advanced and Stressed Breast Cancer

Nian-An Luo, Ya-Qi Qu, Guo-Dong Yang, Tao Wang, Ren-Li Li, Lin-Tao Jia, Rui Dong

Int J Mol Sci. 2014 Nov; 15(11): 20306–20320. Published online 2014 Nov 6. doi: 10.3390/ijms151120306

PMCID:: PMC4264168

Abstract Article PDF–1.8M

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