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Select item 108446331.

Eosinophils preserve bone homeostasis by inhibiting excessive osteoclast formation and activity via eosinophil peroxidase

Darja Andreev, Katerina Kachler, Mengdan Liu, Zhu Chen, Brenda Krishnacoumar, Mark Ringer, Silke Frey, Gerhard Krönke, David Voehringer, Georg Schett, Aline Bozec

Nat Commun. 2024; 15: 1067. Published online 2024 Feb 5. doi: 10.1038/s41467-024-45261-8

PMCID:: PMC10844633

Abstract Article PDF–8.3M

Select item 81650302.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 55316113.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 50709114.

Eosinophil peroxidase activates cells by HER2 receptor engagement and β1-integrin clustering with downstream MAPK cell signaling

Kerrie Hennigan, Paul J. Conroy, Marie-Therese Walsh, Mohamed Amin, Richard O'Kennedy, Patmapriya Ramasamy, Gerald J. Gleich, Zeshan Siddiqui, Senan Glynn, Olive McCabe, Catherine Mooney, Brian J. Harvey, Richard W. Costello, Jean McBryan

Clin Immunol. 2016 Oct; 171: 1–11. doi: 10.1016/j.clim.2016.08.009

PMCID:: PMC5070911

Abstract Article PDF–1.7M

Select item 50639945.

Eosinophil Peroxidase Catalyzed Protein Carbamylation Participates in Asthma

Zeneng Wang, Joseph A. DiDonato, Jennifer Buffa, Suzy A. Comhair, Mark A. Aronica, Raed A. Dweik, Nancy A. Lee, James J. Lee, Mary Jane Thomassen, Mani Kavuru, Serpil C. Erzurum, Stanley L. Hazen

J Biol Chem. 2016 Oct 14; 291(42): 22118–22135. Published online 2016 Sep 1. doi: 10.1074/jbc.M116.750034

PMCID:: PMC5063994

Abstract Article PDF–3.1M

Select item 48035146.

Nasal and Pharyngeal Eosinophil Peroxidase Levels in Adults with Poorly Controlled Asthma Correlate with Sputum Eosinophilia

Matthew A Rank, Sergei I. Ochkur, John C Lewis, Harry G Teaford, III, Lewis J. Wesselius, Richard A. Helmers, Nancy A. Lee, Parameswaran Nair, James J Lee

Allergy. Author manuscript; available in PMC 2017 Apr 1.

Published in final edited form as: Allergy. 2016 Apr; 71(4): 567–570. Published online 2015 Dec 24. doi: 10.1111/all.12817

PMCID:: PMC4803514

Abstract Article PDF–240K

Select item 46172117.

The BioPlex Network: A Systematic Exploration of the Human Interactome

Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2016 Jul 16.

Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043

PMCID:: PMC4617211

Abstract Article PDF–2.2M

Select item 46041558.

Kelch Domain of Gigaxonin Interacts with Intermediate Filament Proteins Affected in Giant Axonal Neuropathy

Bethany L. Johnson-Kerner, Alejandro Garcia Diaz, Sean Ekins, Hynek Wichterle

PLoS One. 2015; 10(10): e0140157. Published online 2015 Oct 13. doi: 10.1371/journal.pone.0140157

PMCID:: PMC4604155

Abstract Article PDF–2.9M

Select item 37880819.

Eosinophil Peroxidase in Sputum Represents a Unique Biomarker of Airway Eosinophilia

Parameswaran Nair, Sergei I. Ochkur, Cheryl Protheroe, Katherine Radford, Ann Efthimiadis, Nancy A. Lee, James J. Lee

Allergy. Author manuscript; available in PMC 2014 Sep 1.

Published in final edited form as: Allergy. 2013 Sep; 68(9): 1177–1184. Published online 2013 Aug 9. doi: 10.1111/all.12206

PMCID:: PMC3788081

Abstract Article PDF–1.3M

Select item 377350510.

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

Simona Principe, E. Ellen Jones, Yunee Kim, Ankit Sinha, Julius O. Nyalwidhe, Jasmin Brooks, O. John Semmes, Dean A. Troyer, Raymond S. Lance, Thomas Kislinger, Richard R. Drake

Proteomics. Author manuscript; available in PMC 2014 May 1.

Published in final edited form as: Proteomics. 2013 May; 13(0): 1667–1671. Published online 2013 Apr 23. doi: 10.1002/pmic.201200561

PMCID:: PMC3773505

Abstract Article PDF–630K

Select item 350863511.

Eosinophil associated genes in the inflammatory bowel disease 4 region: Correlation to inflammatory bowel disease revealed

Kristin Blom, Jenny Rubin, Jonas Halfvarson, Leif Törkvist, Anders Rönnblom, Per Sangfelt, Mikael Lördal, Ulla-Britt Jönsson, Urban Sjöqvist, Lena Douhan Håkansson, Per Venge, Marie Carlson

World J Gastroenterol. 2012 Nov 28; 18(44): 6409–6419. Published online 2012 Nov 28. doi: 10.3748/wjg.v18.i44.6409

PMCID:: PMC3508635

Abstract Article PDF–1012K

Select item 343265612.

A Sensitive High Throughput ELISA for Human Eosinophil Peroxidase: A Specific Assay to Quantify Eosinophil Degranulation from Patient-derived Sources

Sergei I. Ochkur, John Dongil Kim, Cheryl A. Protheroe, Dana Colbert, Rachel M. Condjella, Sophie Bersoux, Richard A. Helmers, Redwan Moqbel, Paige Lacy, Elizabeth A. Kelly, Nizar N. Jarjour, Robert Kern, Anju Peters, Robert P. Schleimer, Glenn T. Furuta, Parameswaran Nair, James J. Lee, Nancy A. Lee

J Immunol Methods. Author manuscript; available in PMC 2013 Oct 31.

Published in final edited form as: J Immunol Methods. 2012 Oct 31; 384(1-2): 10–20. Published online 2012 Jun 28. doi: 10.1016/j.jim.2012.06.011

PMCID:: PMC3432656

Abstract Article PDF–3.9M

Select item 317805913.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 291128214.

Protein Radical Formation Resulting from Eosinophil Peroxidase-catalyzed Oxidation of Sulfite

Kalina Ranguelova, Saurabh Chatterjee, Marilyn Ehrenshaft, Dario C. Ramirez, Fiona A. Summers, Maria B. Kadiiska, Ronald P. Mason

J Biol Chem. 2010 Jul 30; 285(31): 24195–24205. Published online 2010 May 25. doi: 10.1074/jbc.M109.069054

PMCID:: PMC2911282

Abstract Article PDF–2.7M

Select item 289380015.

A Large-scale genetic association study of esophageal adenocarcinoma risk

Chen-yu Liu, Michael C. Wu, Feng Chen, Monica Ter-Minassian, Kofi Asomaning, Rihong Zhai, Zhaoxi Wang, Li Su, Rebecca S. Heist, Matthew H. Kulke, Xihong Lin, Geoffrey Liu, David C. Christiani

Carcinogenesis. 2010 Jul; 31(7): 1259–1263. Published online 2010 May 7. doi: 10.1093/carcin/bgq092

PMCID:: PMC2893800

Abstract Article PDF–84K

Select item 266141216.

Post-translational Tyrosine Nitration of Eosinophil Granule Toxins Mediated by Eosinophil Peroxidase

Martina Ulrich, Alina Petre, Nikolay Youhnovski, Franziska Prömm, Markus Schirle, Michael Schumm, Ralph S. Pero, Alfred Doyle, James Checkel, Hirohito Kita, Nethaji Thiyagarajan, K. Ravi Acharya, Peter Schmid-Grendelmeier, Hans-Uwe Simon, Heinz Schwarz, Masato Tsutsui, Hiroaki Shimokawa, Gabriel Bellon, James J. Lee, Michael Przybylski, Gerd Döring

J Biol Chem. 2008 Oct 17; 283(42): 28629–28640. doi: 10.1074/jbc.M801196200