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Items: 1 to 20 of 49

1.
Cullin 3 Exon 9 Deletion in Familial Hyperkalemic Hypertension Impairs Cullin3-Ring-E3 Ligase (CRL3) Dynamic Regulation and Cycling
Ilektra Kouranti, Waed Abdel Khalek, Stephani Mazurkiewicz, Irmine Loisel-Ferreira, Alexis M. Gautreau, Lionel Pintard, Xavier Jeunemaitre, Eric Clauser
Int J Mol Sci. 2022 May; 23(9): 5151. Published online 2022 May 5. doi: 10.3390/ijms23095151
PMCID:
PMC9105235
AbstractArticlePDF–5.8M
2.
Loss of USP28 and SPINT2 expression promotes cancer cell survival after whole genome doubling
Sara Vanessa Bernhard, Katarzyna Seget-Trzensiok, Christian Kuffer, Dragomir B. Krastev, Lisa-Marie Stautmeister, Mirko Theis, Kristina Keuper, Jan-Eric Boekenkamp, Maik Kschischo, Frank Buchholz, Zuzana Storchova
Cell Oncol (Dordr) 2022; 45(1): 103–119. Published online 2021 Dec 28. doi: 10.1007/s13402-021-00654-5
PMCID:
PMC8881269
AbstractArticlePDF–3.4M
3.
SARS‐CoV‐2–host proteome interactions for antiviral drug discovery
Xiaonan Liu, Sini Huuskonen, Tuomo Laitinen, Taras Redchuk, Mariia Bogacheva, Kari Salokas, Ina Pöhner, Tiina Öhman, Arun Kumar Tonduru, Antti Hassinen, Lisa Gawriyski, Salla Keskitalo, Maria K Vartiainen, Vilja Pietiäinen, Antti Poso, Markku Varjosalo
Mol Syst Biol. 2021 Nov; 17(11): e10396. Published online 2021 Oct 28. doi: 10.15252/msb.202110396
PMCID:
PMC8552907
AbstractArticlePDF–3.9M
4.
An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity
Yuehui Zhang, Limin Shang, Jing Zhang, Yuchen Liu, Chaozhi Jin, Yanan Zhao, Xiaobo Lei, Wenjing Wang, Xia Xiao, Xiuyuan Zhang, Yujiao Liu, Linlin Liu, Meng-Wei Zhuang, Qingkun Mi, Chunyan Tian, Jianwei Wang, Fuchu He, Pei-Hui Wang, Jian Wang
Cell Chem Biol. 2022 Jan 20; 29(1): 5–18.e6. Published online 2021 Oct 20. doi: 10.1016/j.chembiol.2021.10.008
PMCID:
PMC8527578
AbstractArticlePDF–4.5M
5.
The proximal proteome of 17 SARS-CoV-2 proteins links to disrupted antiviral signaling and host translation
Jordan M. Meyers, Muthukumar Ramanathan, Ronald L. Shanderson, Aimee Beck, Laura Donohue, Ian Ferguson, Margaret G. Guo, Deepti S. Rao, Weili Miao, David Reynolds, Xue Yang, Yang Zhao, Yen-Yu Yang, Catherine Blish, Yinsheng Wang, Paul A. Khavari
PLoS Pathog. 2021 Oct; 17(10): e1009412. Published online 2021 Oct 1. doi: 10.1371/journal.ppat.1009412
PMCID:
PMC8513853
AbstractArticlePDF–4.1M
6.
Targeted HAI-2 deletion causes excessive proteolysis with prolonged active prostasin and depletion of HAI-1 monomer in intestinal but not epidermal epithelial cells
Robert B Barndt, Mon-Juan Lee, Nanxi Huang, Dajun D Lu, See-Chi Lee, Po-Wen Du, Chun-Chia Chang, Ping-Feng B Tsai, Yu-Siou K Huang, Hao-Ming Chang, Jehng-Kang Wang, Chih-Hsin Lai, Michael D Johnson, Chen-Yong Lin
Hum Mol Genet. 2021 Oct 1; 30(19): 1833–1850. Published online 2021 Jun 4. doi: 10.1093/hmg/ddab150
PMCID:
PMC8444455
AbstractArticlePDF–1.4M
7.
Comprehensive Analysis of the Expression and Prognostic Value of SPINT1/2 in Breast Carcinoma
Qiulin Wu, Guobing Yin, Jing Luo, Yingzi Zhang, Tiantian Ai, Jiao Tian, Yudi Jin, Jinwei Lei, Shengchun Liu
Front Endocrinol (Lausanne) 2021; 12: 665666. Published online 2021 Jul 26. doi: 10.3389/fendo.2021.665666
PMCID:
PMC8351597
AbstractArticlePDF–18M
8.
The Physiological TMPRSS2 Inhibitor HAI-2 Alleviates SARS-CoV-2 Infection
Yuriko Tomita, Shutoku Matsuyama, Hideo Fukuhara, Katsumi Maenaka, Hiroaki Kataoka, Takao Hashiguchi, Makoto Takeda
J Virol. 2021 Jun; 95(12): e00434-21. Prepublished online 2021 Mar 31. Published online 2021 May 24. doi: 10.1128/JVI.00434-21
PMCID:
PMC8315915
ArticlePDF–301K
9.
Elevated Circulating and Placental SPINT2 Is Associated with Placental Dysfunction
Ciara N. Murphy, Susan P. Walker, Teresa M. MacDonald, Emerson Keenan, Natalie J. Hannan, Mary E. Wlodek, Jenny Myers, Jessica F. Briffa, Tania Romano, Alexandra Roddy Mitchell, Carole-Anne Whigham, Ping Cannon, Tuong-Vi Nguyen, Manju Kandel, Natasha Pritchard, Stephen Tong, Tu’uhevaha J. Kaitu’u-Lino
Int J Mol Sci. 2021 Jul; 22(14): 7467. Published online 2021 Jul 12. doi: 10.3390/ijms22147467
PMCID:
PMC8305184
AbstractArticlePDF–2.0M
10.
The endogenous cellular protease inhibitor SPINT2 controls SARS-CoV-2 viral infection and is associated to disease severity
Carlos Ramirez Alvarez, Carmon Kee, Ashwini Kumar Sharma, Leonie Thomas, Florian I. Schmidt, Megan L. Stanifer, Steeve Boulant, Carl Herrmann
PLoS Pathog. 2021 Jun; 17(6): e1009687. Published online 2021 Jun 28. doi: 10.1371/journal.ppat.1009687
PMCID:
PMC8270430
AbstractArticlePDF–3.1M
11.
Comparative Host Interactomes of the SARS-CoV-2 Nonstructural Protein 3 and Human Coronavirus Homologs
Katherine M. Almasy, Jonathan P. Davies, Lars Plate
Mol Cell Proteomics. 2021; 20: 100120. Published online 2021 Jun 27. doi: 10.1016/j.mcpro.2021.100120
PMCID:
PMC8236078
AbstractArticlePDF–4.6M
12.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
13.
Quantitative Proteomics Links the LRRC59 Interactome to mRNA Translation on the ER Membrane
Molly M. Hannigan, Alyson M. Hoffman, J. Will Thompson, Tianli Zheng, Christopher V. Nicchitta
Mol Cell Proteomics. 2020 Nov; 19(11): 1826–1849. Published online 2020 Aug 10. doi: 10.1074/mcp.RA120.002228
PMCID:
PMC7664120
AbstractArticlePDF–4.8M
14.
LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling
Jin Huk Choi, Xue Zhong, William McAlpine, Tzu-Chieh Liao, Duanwu Zhang, Beibei Fang, Jamie Russell, Sara Ludwig, Evan Nair-Gill, Zhao Zhang, Kuan-wen Wang, Takuma Misawa, Xiaoming Zhan, Mihwa Choi, Tao Wang, Xiaohong Li, Miao Tang, Qihua Sun, Liyang Yu, Anne R. Murray, Eva Marie Y. Moresco, Bruce Beutler
Science. Author manuscript; available in PMC 2020 May 8.
Published in final edited form as: Science. 2019 May 10; 364(6440): eaau0812. doi: 10.1126/science.aau0812
PMCID:
PMC7206793
AbstractArticlePDF–2.2M
15.
SPINT2 inhibits proteases involved in activation of both influenza viruses and metapneumoviruses
Marco R. Straus, Jonathan T. Kinder, Michal Segall, Rebecca Ellis Dutch, Gary R. Whittaker
Virology. 2020 Apr; 543: 43–53. Published online 2020 Jan 7. doi: 10.1016/j.virol.2020.01.004
PMCID:
PMC7112099
AbstractArticlePDF–1.5M
16.
PTPRA Phosphatase Regulates GDNF-Dependent RET Signaling and Inhibits the RET Mutant MEN2A Oncogenic Potential
Leena Yadav, Elina Pietilä, Tiina Öhman, Xiaonan Liu, Arun K. Mahato, Yulia Sidorova, Kaisa Lehti, Mart Saarma, Markku Varjosalo
iScience. 2020 Feb 21; 23(2): 100871. Published online 2020 Jan 31. doi: 10.1016/j.isci.2020.100871
PMCID:
PMC7021549
AbstractArticlePDF–8.1M
17.
Case of Syndromic Tufting Enteropathy Harbors SPINT2 Mutation seen in Congenital Sodium Diarrhea
Mamata Sivagnanam, Andreas R. Janecke, Thomas Müller, Peter Heinz-Erian, Sharon Taylor, Lynne M. Bird
Clin Dysmorphol. Author manuscript; available in PMC 2019 Aug 26.
Published in final edited form as: Clin Dysmorphol. 2010 Jan; 19(1): 48. doi: 10.1097/MCD.0b013e328331de38
PMCID:
PMC6709868
ArticlePDF–31K
18.
HAI-2 as a novel inhibitor of plasmin represses lung cancer cell invasion and metastasis
Shang-Ru Wu, Chia-Hao Lin, Han-Po Shih, Chun-Jung Ko, Hsin-Ying Lin, Shao-Wei Lan, Hsin-Hsien Lin, Hsin-Fang Tu, Chao-Chi Ho, Hsiang-Po Huang, Ming-Shyue Lee
Br J Cancer. 2019 Mar 5; 120(5): 499–511. Published online 2019 Feb 15. doi: 10.1038/s41416-019-0400-2
PMCID:
PMC6461989
AbstractArticlePDF–4.2M
19.
Up‐regulation of SPINT2/HAI‐2 by Azacytidine in bone marrow mesenchymal stromal cells affects leukemic stem cell survival and adhesion
Fernanda Marconi Roversi, Nathalia Moreno Cury, Matheus Rodrigues Lopes, Karla Priscila Ferro, João Agostinho Machado‐Neto, Marisa Claudia Alvarez, Gabriela Pereira dos Santos, Renata Giardini Rosa, Ana Leda Longhini, Adriana da Silva Santos Duarte, Fernando Vieira Pericole, Patricia Favaro, José Andres Yunes, Sara Teresinha Olalla Saad
J Cell Mol Med. 2019 Feb; 23(2): 1562–1571. Published online 2018 Nov 28. doi: 10.1111/jcmm.14066
PMCID:
PMC6349149
AbstractArticlePDF–869K
20.
The Shieldin complex mediates 53BP1-dependent DNA repair
Sylvie M. Noordermeer, Salomé Adam, Dheva Setiaputra, Marco Barazas, Stephen J. Pettitt, Alexanda K. Ling, Michele Olivieri, Alejandro Álvarez-Quilón, Nathalie Moatti, Michal Zimmermann, Stefano Annunziato, Dragomir B. Krastev, Feifei Song, Inger Brandsma, Jessica Frankum, Rachel Brough, Alana Sherker, Sébastien Landry, Rachel K. Szilard, Meagan M. Munro, Andrea McEwan, Théo Goullet de Rugy, Zhen-Yuan Lin, Traver Hart, Jason Moffat, Anne-Claude Gingras, Alberto Martin, Haico van Attikum, Jos Jonkers, Christopher J. Lord, Sven Rottenberg, Daniel Durocher
Nature. Author manuscript; available in PMC 2019 Jan 18.
Published in final edited form as: Nature. 2018 Aug; 560(7716): 117–121. Published online 2018 Jul 18. doi: 10.1038/s41586-018-0340-7
PMCID:
PMC6141009
AbstractArticlePDF–5.1M

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