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Select item 96452561.

LncRNA MINCR attenuates osteoarthritis progression via sponging miR-146a-5p to promote BMPR2 expression

Dongyun Li, Xiaoying Wang, Tengda Yi, Lin Zhang, Lirui Feng, Mingxing Zhang, Yongsheng He, Shunkui Gang

Cell Cycle. 2022; 21(22): 2417–2432. Published online 2022 Jul 18. doi: 10.1080/15384101.2022.2099191

PMCID:: PMC9645256

Abstract Article PDF–4.2M

Select item 92601242.

Single-cell RNA sequencing reveals that BMPR2 mutation regulates right ventricular function via ID genes

Mingxia Du, Haibin Jiang, Hongxian Liu, Xin Zhao, Yu Zhou, Fang Zhou, Chunmei Piao, Guoqiang Xu, Feng Ma, Jianan Wang, Frederic Perros, Nicholas W. Morrell, Hong Gu, Jun Yang

Eur Respir J. 2022 Jul; 60(1): 2100327. Published online 2022 Jul 7. doi: 10.1183/13993003.00327-2021

PMCID:: PMC9260124

Abstract Article PDF–2.0M

Select item 73489933.

The BMP Receptor 2 in Pulmonary Arterial Hypertension: When and Where the Animal Model Matches the Patient

Chris Happé, Kondababu Kurakula, Xiao-Qing Sun, Denielli da Silva Goncalves Bos, Nina Rol, Christophe Guignabert, Ly Tu, Ingrid Schalij, Karien C. Wiesmeijer, Olga Tura-Ceide, Anton Vonk Noordegraaf, Frances S. de Man, Harm Jan Bogaard, Marie-José Goumans

Cells. 2020 Jun; 9(6): 1422. Published online 2020 Jun 8. doi: 10.3390/cells9061422

PMCID:: PMC7348993

Abstract Article PDF–1.8M

Select item 70526664.

BMPR2 dysfunction impairs insulin signaling and glucose homeostasis in cardiomyocytes

Anna R. Hemnes, Joshua P. Fessel, Xinping Chen, Shijun Zhu, Niki L. Fortune, Christopher Jetter, Michael Freeman, John H. Newman, James D. West, Megha H. Talati

Am J Physiol Lung Cell Mol Physiol. 2020 Feb 1; 318(2): L429–L441. Published online 2019 Dec 18. doi: 10.1152/ajplung.00555.2018

PMCID:: PMC7052666

Abstract Article

Select item 68030525.

Phenotypically-Silent Bone Morphogenetic Protein Receptor 2 (Bmpr2) Mutations Predispose Rats to Inflammation-Induced Pulmonary Arterial Hypertension by Enhancing The Risk for Neointimal Transformation

Wen Tian, Xinguo Jiang, Yon K. Sung, Eric Shuffle, Ting-Hsuan Wu, Peter N. Kao, Allen B. Tu, Peter Dorfmüller, Aiqin Cao, Lingli Wang, Gongyong Peng, Yesl Kim, Patrick Zhang, James Chappell, Shravani Pasupneti, Petra Dahms, Peter Maguire, Hassan Chaib, Roham Zamanian, Marc Peters-Golden, Michael P. Snyder, Norbert F. Voelkel, Marc Humbert, Marlene Rabinovitch, Mark R. Nicolls

Circulation. Author manuscript; available in PMC 2020 Oct 22.

Published in final edited form as: Circulation. 2019 Oct 22; 140(17): 1409–1425. Published online 2019 Aug 29. doi: 10.1161/CIRCULATIONAHA.119.040629

PMCID:: PMC6803052

Abstract Article PDF–3.9M

Select item 58663416.

Network of MicroRNAs Mediate Translational Repression of Bone Morphogenetic Protein Receptor‐2: Involvement in HIV‐Associated Pulmonary Vascular Remodeling

Mahendran Chinnappan, Aradhana Mohan, Stuti Agarwal, Pranjali Dalvi, Navneet K. Dhillon

J Am Heart Assoc. 2018 Mar 6; 7(5): e008472. Published online 2018 Feb 25. doi: 10.1161/JAHA.117.008472

PMCID:: PMC5866341

Abstract Article PDF–1.6M

Select item 53032127.

Let-7a-transfected mesenchymal stem cells ameliorate monocrotaline-induced pulmonary hypertension by suppressing pulmonary artery smooth muscle cell growth through STAT3-BMPR2 signaling

Gesheng Cheng, Xingye Wang, Yongxin Li, Lu He

Stem Cell Res Ther. 2017; 8: 34. Published online 2017 Feb 10. doi: 10.1186/s13287-017-0480-y

PMCID:: PMC5303212

Abstract Article PDF–1.8M

Select item 49723978.

E-cadherin interactome complexity and robustness resolved by quantitative proteomics

Zhenhuan Guo, Lisa J Neilson, Hang Zhong, Paul S Murray, Megha Vaman Rao, Sara Zanivan, Ronen Zaidel-Bar

Sci Signal. Author manuscript; available in PMC 2016 Aug 3.

Published in final edited form as: Sci Signal. 2014 Dec 2; 7(354): rs7. Published online 2014 Dec 2. doi: 10.1126/scisignal.2005473

PMCID:: PMC4972397

Abstract Article PDF–3.1M

Select item 48386379.

Bone morphogenetic protein signalling in heritable versus idiopathic pulmonary hypertension

Laurence Dewachter, Serge Adnot, Christophe Guignabert, Ly Tu, Elisabeth Marcos, Elie Fadel, Marc Humbert, Philippe Dartevelle, Gérald Simonneau, Robert Naeije, Saadia Eddahibi

Eur Respir J. Author manuscript;

Published in final edited form as: Eur Respir J. 2009 Nov; 34(5): 1100–1110. Published online 2009 Mar 26. doi: 10.1183/09031936.00183008

PMCID:: PMC4838637

Abstract Article

Select item 475924110.

Evolving New Skeletal Traits by cis-Regulatory Changes in Bone Morphogenetic Proteins

Vahan B. Indjeian, Garrett A. Kingman, Felicity C. Jones, Catherine A. Guenther, Jane Grimwood, Jeremy Schmutz, Richard M. Myers, David M. Kingsley

Cell. Author manuscript; available in PMC 2017 Jan 14.

Published in final edited form as: Cell. 2016 Jan 14; 164(0): 45–56. Published online 2016 Jan 7. doi: 10.1016/j.cell.2015.12.007

PMCID:: PMC4759241

Abstract Article PDF–2.7M

Select item 473230311.

VE-cadherin facilitates BMP-induced endothelial cell permeability and signaling

Andreas Benn, Clara Bredow, Isabel Casanova, Slobodan Vukičević, Petra Knaus

J Cell Sci. 2016 Jan 1; 129(1): 206–218. doi: 10.1242/jcs.179960

PMCID:: PMC4732303

Abstract Article

Select item 449629512.

Selective enhancement of endothelial BMPR-II with BMP9 reverses pulmonary arterial hypertension

Lu Long, Mark L. Ormiston, Xudong Yang, Mark Southwood, Stefan Gräf, Rajiv D. Machado, Matthias Mueller, Bernd Kinzel, Lai Ming Yung, Janine M. Wilkinson, Stephen D. Moore, Kylie M. Drake, Micheala A. Aldred, Paul Yu, Paul D. Upton, Nicholas W. Morrell

Nat Med. Author manuscript; available in PMC 2016 Jan 1.

Published in final edited form as: Nat Med. 2015 Jul; 21(7): 777–785. Published online 2015 Jun 15. doi: 10.1038/nm.3877

PMCID:: PMC4496295

Abstract Article PDF–2.0M

Select item 425190013.

BMP4 Increases the Expression of TRPC and Basal [Ca²⁺]_i via the p38MAPK and ERK1/2 Pathways Independent of BMPRII in PASMCs

Yi Zhang, Yingfeng Wang, Kai Yang, Lichun Tian, Xin Fu, Yan Wang, Yueqian Sun, Qian Jiang, Wenju Lu, Jian Wang

PLoS One. 2014; 9(12): e112695. Published online 2014 Dec 2. doi: 10.1371/journal.pone.0112695

PMCID:: PMC4251900

Abstract Article PDF–1.3M

Select item 415476214.

Functional Changes in Pulmonary Arterial Endothelial Cells Associated with BMPR2 Mutations

Hu Wang, Ruirui Ji, Jie Meng, Qiqiong Cui, Wenxin Zou, Lei Li, Guoliang Wang, Li Sun, Zhaohui Li, Lei Huo, Yuxin Fan, Daniel J. Penny

PLoS One. 2014; 9(9): e106703. Published online 2014 Sep 4. doi: 10.1371/journal.pone.0106703

PMCID:: PMC4154762

Abstract Article PDF–1.3M

Select item 392083415.

Genetic ablation of the Bmpr2 gene in pulmonary endothelium is sufficient to predispose to pulmonary arterial hypertension

Kwon-Ho Hong, Young Jae Lee, Eunji Lee, Sung Ok Park, Chul Han, Hideyuki Beppu, En Li, Mohan Raizada, Kenneth D. Bloch, S. Paul Oh

Circulation. Author manuscript; available in PMC 2014 Feb 11.

Published in final edited form as: Circulation. 2008 Aug 12; 118(7): 722–730. Published online 2008 Jul 28. doi: 10.1161/CIRCULATIONAHA.107.736801

PMCID:: PMC3920834

Abstract Article PDF–1.9M

Select item 377655716.

MEGF8 is a modifier of BMP signaling in trigeminal sensory neurons

Caitlin Engelhard, Sarah Sarsfield, Janna Merte, Qiang Wang, Peng Li, Hideyuki Beppu, Alex L Kolodkin, Henry M Sucov, David D Ginty

eLife. 2013; 2: e01160. Published online 2013 Sep 17. doi: 10.7554/eLife.01160

PMCID:: PMC3776557

Abstract Article PDF–3.4M

Select item 372615317.

FK506 activates BMPR2, rescues endothelial dysfunction, and reverses pulmonary hypertension

Edda Spiekerkoetter, Xuefei Tian, Jie Cai, Rachel K. Hopper, Deepti Sudheendra, Caiyun G. Li, Nesrine El-Bizri, Hirofumi Sawada, Roxanna Haghighat, Roshelle Chan, Leila Haghighat, Vinicio de Jesus Perez, Lingli Wang, Sushma Reddy, Mingming Zhao, Daniel Bernstein, David E. Solow-Cordero, Philip A. Beachy, Thomas J. Wandless, Peter ten Dijke, Marlene Rabinovitch

J Clin Invest. 2013 Aug 1; 123(8): 3600–3613. Published online 2013 Jul 15. doi: 10.1172/JCI65592

PMCID:: PMC3726153

Abstract Article PDF–3.6M

Select item 366885118.

BMPR2 is required for postimplantation uterine function and pregnancy maintenance

Takashi Nagashima, Qinglei Li, Caterina Clementi, John P. Lydon, Francesco J. DeMayo, Martin M. Matzuk

J Clin Invest. 2013 Jun 3; 123(6): 2539–2550. Published online 2013 May 8. doi: 10.1172/JCI65710

PMCID:: PMC3668851

Abstract Article PDF–7.1M

Select item 362764819.

Rnf165/Ark2C Enhances BMP-Smad Signaling to Mediate Motor Axon Extension

Claire E. Kelly, Efstathia Thymiakou, James E. Dixon, Shinya Tanaka, Jonathan Godwin, Vasso Episkopou

PLoS Biol. 2013 Apr; 11(4): e1001538. Published online 2013 Apr 16. doi: 10.1371/journal.pbio.1001538

PMCID:: PMC3627648

Abstract Article PDF–3.1M

Select item 358712220.

Hereditary spastic paraplegia-causing mutations in atlastin-1 interfere with BMPRII trafficking

Jiali Zhao, Peter Hedera

Mol Cell Neurosci. Author manuscript; available in PMC 2014 Jan 1.

Published in final edited form as: Mol Cell Neurosci. 2013 Jan; 52: 87–96. Published online 2012 Oct 16. doi: 10.1016/j.mcn.2012.10.005

PMCID:: PMC3587122

Abstract Article PDF–3.9M

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