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Select item 108242741.

Impaired hemostatic activity of healthy transfused platelets in inherited and acquired platelet disorders: mechanisms and implications

Robert H. Lee, Raymond Piatt, Ankita Dhenge, María L. Lozano, Verónica Palma-Barqueros, José Rivera, Wolfgang Bergmeier

Sci Transl Med. Author manuscript; available in PMC 2024 Jan 29.

Published in final edited form as: Sci Transl Med. 2019 Dec 11; 11(522): eaay0203. doi: 10.1126/scitranslmed.aay0203

PMCID:: PMC10824274

Abstract Article PDF–1.6M

Select item 104451242.

Megakaryocyte NLRP3 hyperactivation induces mild anemia and potentiates inflammatory response in mice

Joshua H. Bourne, Joana Campos, Sophie J. Hopkin, Katharine Whitworth, James Palis, Yotis A. Senis, Julie Rayes, Asif J. Iqbal, Alexander Brill

Front Immunol. 2023; 14: 1226196. Published online 2023 Aug 9. doi: 10.3389/fimmu.2023.1226196

PMCID:: PMC10445124

Abstract Article PDF–1.6M

Select item 89342723.

Platelet glycoprotein Ibα provides radiation protection

Adam Corken, Sanchita P. Ghosh, Ruofei Du, Marjan Boerma, Jerry Ware, Rupak Pathak

Radiother Oncol. Author manuscript; available in PMC 2023 Feb 1.

Published in final edited form as: Radiother Oncol. 2022 Feb; 167: 143–148. Published online 2021 Dec 28. doi: 10.1016/j.radonc.2021.12.030

PMCID:: PMC8934272

Abstract Article PDF–1.1M

Select item 81582494.

Calcium ion chelation preserves platelet function during cold storage

Binggang Xiang, Guoying Zhang, Yan Zhang, Congqing Wu, Smita Joshi, Andrew J. Morris, Jerry Ware, Susan S. Smyth, Sidney W. Whiteheart, Zhenyu Li

Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2022 Jan 1.

Published in final edited form as: Arterioscler Thromb Vasc Biol. 2021 Jan; 41(1): 234–249. Published online 2020 Nov 12. doi: 10.1161/ATVBAHA.120.314879

PMCID:: PMC8158249

Abstract Article PDF–2.8M

Select item 79387705.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 77762456.

Desialylation of O-glycans on glycoprotein Ibα drives receptor signaling and platelet clearance

Yingchun Wang, Wenchun Chen, Wei Zhang, Melissa M. Lee-Sundlov, Caterina Casari, Michael C. Berndt, Francois Lanza, Wolfgang Bergmeier, Karin M. Hoffmeister, X. Frank Zhang, Renhao Li

Haematologica. 2021 Jan 1; 106(1): 220–229. Published online 2020 Jan 23. doi: 10.3324/haematol.2019.240440

PMCID:: PMC7776245

Abstract Article PDF–3.9M

Select item 74799537.

von Willebrand factor variant D1472H has no effect in mice with humanized VWF-platelet interactions

Hannah K. Lohmeier, Tricia L. Slobodianuk, Sachiko Kanaji, Sandra L. Haberichter, Robert R. Montgomery, Veronica H. Flood

Blood Adv. 2020 Sep 8; 4(17): 4065–4068. Published online 2020 Aug 31. doi: 10.1182/bloodadvances.2020002629

PMCID:: PMC7479953

Abstract Article PDF–698K

Select item 70661728.

Red blood cell-derived semaphorin 7A promotes thrombo-inflammation in myocardial ischemia-reperfusion injury through platelet GPIb

David Köhler, Tiago Granja, Julia Volz, Michael Koeppen, Harald F. Langer, Georg Hansmann, Ekaterina Legchenko, Tobias Geisler, Tamam Bakchoul, Claudia Eggstein, Helene A. Häberle, Bernhard Nieswandt, Peter Rosenberger

Nat Commun. 2020; 11: 1315. Published online 2020 Mar 11. doi: 10.1038/s41467-020-14958-x

PMCID:: PMC7066172

Abstract Article PDF–2.0M

Select item 64844579.

The Gp1ba-Cre transgenic mouse: a new model to delineate platelet and leukocyte functions

Zoltan Nagy, Timo Vögtle, Mitchell J. Geer, Jun Mori, Silke Heising, Giada Di Nunzio, Ralph Gareus, Alexander Tarakhovsky, Arthur Weiss, Benjamin G. Neel, Guillaume E. Desanti, Alexandra Mazharian, Yotis A. Senis

Blood. 2019 Jan 24; 133(4): 331–343. Prepublished online 2018 Nov 14. doi: 10.1182/blood-2018-09-877787

PMCID:: PMC6484457

Abstract Article

Select item 646438910.

Platelet Protein Disulfide Isomerase Promotes Glycoprotein Ibα-Mediated Platelet-Neutrophil Interactions Under Thromboinflammatory Conditions

Jing Li, Kyungho Kim, Si-Yeon Jeong, Joyce Chiu, Bei Xiong, Pavel A. Petukhov, Xiangrong Dai, Xiaoyi Li, Robert K. Andrews, Xiaoping Du, Philip J. Hogg, Jaehyung Cho

Circulation. Author manuscript; available in PMC 2020 Mar 5.

Published in final edited form as: Circulation. 2019 Mar 5; 139(10): 1300–1319. doi: 10.1161/CIRCULATIONAHA.118.036323

Correction in:: Circulation. 2019 Mar 5; 139(10): e529.

PMCID:: PMC6464389

Abstract Article PDF–2.6M

Select item 637375511.

Synthetic glycopolymers and natural fucoidans cause human platelet aggregation via PEAR1 and GPIbα

Caroline Kardeby, Knut Fälker, Elizabeth J. Haining, Maarten Criel, Madelene Lindkvist, Ruben Barroso, Peter Påhlsson, Liza U. Ljungberg, Mattias Tengdelius, G. Ed Rainger, Stephanie Watson, Johannes A. Eble, Marc F. Hoylaerts, Jonas Emsley, Peter Konradsson, Steve P. Watson, Yi Sun, Magnus Grenegård

Blood Adv. 2019 Feb 12; 3(3): 275–287. Published online 2019 Jan 30. doi: 10.1182/bloodadvances.2018024950

PMCID:: PMC6373755

Abstract Article PDF–1.9M

Select item 632243112.

Synergistic Activation of the Mc2r Promoter by FOXL2 and NR5A1 in Mice

Wei-Hsiung Yang, Ninoska M. Gutierrez, Lizhong Wang, Buffy S. Ellsworth, Chiung-Min Wang

Biol Reprod. 2010 Nov 1; 83(5): 842–851. doi: 10.1095/biolreprod.110.085621

PMCID:: PMC6322431

Abstract Article PDF–411K

Select item 620224413.

A Functional Relevance of the Anaphylatoxin Receptor C3aR for Platelet Function and Arterial Thrombus Formation Marks an Intersection Point Between Innate Immunity and Thrombosis

Reinhard J. Sauter, Manuela Sauter, Edimara S. Reis, Frederic N. Emschermann, Henry Nording, Sonja Ebenhöch, Peter Kraft, Patrick Münzer, Maximilian Mauler, Johannes Rheinlaender, Johannes Madlung, Frank Edlich, Tilman E. Schäffer, Sven G. Meuth, Daniel Dürschmied, Tobias Geisler, Oliver Borst, Meinrad Gawaz, Christoph Kleinschnitz, John D. Lambris, Harald F. Langer

Circulation. Author manuscript; available in PMC 2019 Oct 16.

Published in final edited form as: Circulation. 2018 Oct 16; 138(16): 1720–1735. doi: 10.1161/CIRCULATIONAHA.118.034600

Correction in:: Circulation. 2019 Jan 15; 139(3): e8.

PMCID:: PMC6202244

Abstract Article PDF–1.1M

Select item 555357414.

The disulfide isomerase ERp72 supports arterial thrombosis in mice

Junsong Zhou, Yi Wu, Fengwu Chen, Lu Wang, Lubica Rauova, Vincent M. Hayes, Mortimer Poncz, Hong Li, Tong Liu, Junling Liu, David W. Essex

Blood. 2017 Aug 10; 130(6): 817–828. Prepublished online 2017 Jun 2. doi: 10.1182/blood-2016-12-755587

PMCID:: PMC5553574

Abstract Article

Select item 548174215.

A Cdc42/RhoA regulatory circuit downstream of glycoprotein Ib guides transendothelial platelet biogenesis

Sebastian Dütting, Frederique Gaits-Iacovoni, David Stegner, Michael Popp, Adrien Antkowiak, Judith M.M. van Eeuwijk, Paquita Nurden, Simon Stritt, Tobias Heib, Katja Aurbach, Oguzhan Angay, Deya Cherpokova, Niels Heinz, Ayesha A. Baig, Maximilian G. Gorelashvili, Frank Gerner, Katrin G. Heinze, Jerry Ware, Georg Krohne, Zaverio M. Ruggeri, Alan T. Nurden, Harald Schulze, Ute Modlich, Irina Pleines, Cord Brakebusch, Bernhard Nieswandt

Nat Commun. 2017; 8: 15838. Published online 2017 Jun 15. doi: 10.1038/ncomms15838

PMCID:: PMC5481742

Abstract Article PDF–5.8M

Select item 547751916.

Leukocyte integrin Mac-1 regulates thrombosis via interaction with platelet GPIbα

Yunmei Wang, Huiyun Gao, Can Shi, Paul W. Erhardt, Alexander Pavlovsky, Dmitry A. Soloviev, Kamila Bledzka, Valentin Ustinov, Liang Zhu, Jun Qin, Adam D. Munday, Jose Lopez, Edward Plow, Daniel I. Simon

Nat Commun. 2017; 8: 15559. Published online 2017 May 30. doi: 10.1038/ncomms15559

Correction in:: Nat Commun. 2017; 8: 16124.

PMCID:: PMC5477519

Abstract Article PDF–1.2M

Select item 540906917.

Megakaryocytes compensate for Kit insufficiency in murine arthritis

Pierre Cunin, Loka R. Penke, Jonathan N. Thon, Paul A. Monach, Tatiana Jones, Margaret H. Chang, Mary M. Chen, Imene Melki, Steve Lacroix, Yoichiro Iwakura, Jerry Ware, Michael F. Gurish, Joseph E. Italiano, Eric Boilard, Peter A. Nigrovic

J Clin Invest. 2017 May 1; 127(5): 1714–1724. Published online 2017 Apr 4. doi: 10.1172/JCI84598

PMCID:: PMC5409069

Abstract Article PDF–1.8M

Select item 492914818.

Defective association of the platelet glycoprotein Ib-IX complex with the glycosphingolipid-enriched membrane domain inhibits murine thrombus and atheroma formation

Hao Zhou, Yali Ran, Qi Da, Tanner S. Shaw, Dan Shang, Anilkumar K. Reddy, José A. López, Christie M. Ballantyne, Jerry Ware, Huaizhu Wu, Yuandong Peng

J Immunol. Author manuscript; available in PMC 2017 Jul 1.

Published in final edited form as: J Immunol. 2016 Jul 1; 197(1): 288–295. Published online 2016 May 20. doi: 10.4049/jimmunol.1501946

PMCID:: PMC4929148

Abstract Article PDF–2.2M

Select item 482825119.

Allosterism-based Simultaneous, Dual Anticoagulant and Antiplatelet Action. Allosteric Inhibitor Targeting the Glycoprotein Ibα and Heparin-Binding Site of Thrombin

Akul Y. Mehta, Bassem M. Mohammed, Erika J. Martin, Donald F. Brophy, David Gailani, Umesh R. Desai

J Thromb Haemost. Author manuscript; available in PMC 2017 Apr 1.

Published in final edited form as: J Thromb Haemost. 2016 Apr; 14(4): 828–838. Published online 2016 Feb 16. doi: 10.1111/jth.13254

PMCID:: PMC4828251

Abstract Article PDF–906K

Select item 457387120.

Platelets induce apoptosis via membrane-bound FasL

Rebecca I. Schleicher, Frank Reichenbach, Peter Kraft, Anil Kumar, Mario Lescan, Franziska Todt, Kerstin Göbel, Ingo Hilgendorf, Tobias Geisler, Axel Bauer, Marcus Olbrich, Martin Schaller, Sebastian Wesselborg, Lorraine O’Reilly, Sven G. Meuth, Klaus Schulze-Osthoff, Meinrad Gawaz, Xuri Li, Christoph Kleinschnitz, Frank Edlich, Harald F. Langer

Blood. 2015 Sep 17; 126(12): 1483–1493. Prepublished online 2015 Jul 31. doi: 10.1182/blood-2013-12-544445

Correction in:: Blood. 2016 Jan 14; 127(2): 270.

PMCID:: PMC4573871

Abstract Article

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