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Items: 1 to 20 of 69

1.
NDRG1 upregulation by ubiquitin proteasome system dysfunction aggravates neurodegeneration
Tomonori Hoshino, Atsushi Mukai, Hirofumi Yamashita, Hidemi Misawa, Makoto Urushitani, Yoshitaka Tashiro, Shu-ichi Matsuzawa, Ryosuke Takahashi
Mol Brain. 2024; 17: 77. Published online 2024 Oct 23. doi: 10.1186/s13041-024-01150-1
PMCID:
PMC11515609
AbstractArticlePDF–1.0M
2.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
3.
Identification of new ciliary signaling pathways in the brain and insights into neurological disorders
Abdelhalim Loukil, Emma Ebright, Akiyoshi Uezu, Yudong Gao, Scott H Soderling, Sarah C. Goetz
Version 1. bioRxiv. Preprint. 2023 Dec 21. doi: 10.1101/2023.12.20.572700
PMCID:
PMC10769350
AbstractArticlePDF–11M
4.
Loss of NDR1/2 kinases impairs endomembrane trafficking and autophagy leading to neurodegeneration
Flavia Roşianu, Simeon R Mihaylov, Noreen Eder, Antonie Martiniuc, Suzanne Claxton, Helen R Flynn, Shamsinar Jalal, Marie-Charlotte Domart, Lucy Collinson, Mark Skehel, Ambrosius P Snijders, Matthias Krause, Sharon A Tooze, Sila K Ultanir
Life Sci Alliance. 2023 Feb; 6(2): e202201712. Published online 2022 Nov 29. doi: 10.26508/lsa.202201712
PMCID:
PMC9711861
AbstractArticlePDF–10M
5.
NDRG1 is induced by antigen-receptor signaling but dispensable for B and T cell self-tolerance
Rose Hodgson, Xijin Xu, Consuelo Anzilotti, Mukta Deobagkar-Lele, Tanya L. Crockford, Jessica D. Kepple, Eleanor Cawthorne, Aneesha Bhandari, Alberto Cebrian-Serrano, Martin J. Wilcock, Benjamin Davies, Richard J. Cornall, Katherine R. Bull
Commun Biol. 2022; 5: 1216. Published online 2022 Nov 10. doi: 10.1038/s42003-022-04118-w
PMCID:
PMC9649591
AbstractArticlePDF–2.7M
6.
The Deubiquitinating Enzyme USP48 Interacts with the Retinal Degeneration-Associated Proteins UNC119a and ARL3
Laura Sánchez-Bellver, Andrea Férriz-Gordillo, Marc Carrillo-Pz, Laura Rabanal, Francesc R. Garcia-Gonzalo, Gemma Marfany
Int J Mol Sci. 2022 Oct; 23(20): 12527. Published online 2022 Oct 19. doi: 10.3390/ijms232012527
PMCID:
PMC9603860
AbstractArticlePDF–3.4M
7.
Aberrant Neuregulin 1/ErbB Signaling in Charcot-Marie-Tooth Type 4D Disease
Li-Ting Jiang, Yu-Hui Chen, Jie-Hong Huang, Wei-Fang Tong, Ling-Jing Jin, Li-Xi Li
Mol Cell Biol. 2022 Jul; 42(7): e00559-21. Published online 2022 Jun 16. doi: 10.1128/mcb.00559-21
PMCID:
PMC9302083
AbstractArticlePDF–5.7M
8.
Urinary FABP1 is a biomarker for impaired proximal tubular protein reabsorption and is synergistically enhanced by concurrent liver injury
Ryo Kawakami, Miki Matsui, Ayumu Konno, Ryosuke Kaneko, Shreya Shrestha, Suman Shrestha, Hiroaki Sunaga, Hirofumi Hanaoka, Sawako Goto, Michihiro Hosojima, Hideyuki Kabasawa, Masaru Obokata, Norimichi Koitabashi, Hiroki Matsui, Tsutomu Sasaki, Akihiko Saito, Motoko Yanagita, Hirokazu Hirai, Masahiko Kurabayashi, Tatsuya Iso
J Pathol. 2021 Dec; 255(4): 362–373. Published online 2021 Sep 1. doi: 10.1002/path.5775
PMCID:
PMC9292749
AbstractArticlePDF–23M
9.
Targeting Wnt/tenascin C-mediated cross talk between pancreatic cancer cells and stellate cells via activation of the metastasis suppressor NDRG1
Bekesho Geleta, Faten S. Tout, Syer Choon Lim, Sumit Sahni, Patric J. Jansson, Minoti V. Apte, Des R. Richardson, Žaklina Kovačević
J Biol Chem. 2022 Mar; 298(3): 101608. Published online 2022 Jan 20. doi: 10.1016/j.jbc.2022.101608
PMCID:
PMC8881656
AbstractArticlePDF–5.5M
10.
N-myc downstream regulated gene 1 suppresses osteoblast differentiation through inactivating Wnt/β-catenin signaling
Xiaoli Shi, Yunzhu Cen, Liying Shan, Lijie Tian, Endong Zhu, Hairui Yuan, Xiaoxia Li, Ying Liu, Baoli Wang
Stem Cell Res Ther. 2022; 13: 53. Published online 2022 Feb 4. doi: 10.1186/s13287-022-02714-5
PMCID:
PMC8817551
AbstractArticlePDF–14M
11.
N-myc downstream regulated family member 1 (NDRG1) is enriched in myelinating oligodendrocytes and impacts myelin degradation in response to demyelination.
Damien Marechal, David K. Dansu, Kamilah Castro, Julia Patzig, Laura Magri, Benjamin Inbar, Mar Gacias, Sarah Moyon, Patrizia Casaccia
Glia. Author manuscript; available in PMC 2023 Feb 1.
Published in final edited form as: Glia. 2022 Feb; 70(2): 321–336. Published online 2021 Oct 23. doi: 10.1002/glia.24108
PMCID:
PMC8753715
AbstractArticlePDF–2.3M
12.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
13.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
14.
Characterization of an eutherian gene cluster generated after transposon domestication identifies Bex3 as relevant for advanced neurological functions
Enrique Navas-Pérez, Cristina Vicente-García, Serena Mirra, Demian Burguera, Noèlia Fernàndez-Castillo, José Luis Ferrán, Macarena López-Mayorga, Marta Alaiz-Noya, Irene Suárez-Pereira, Ester Antón-Galindo, Fausto Ulloa, Carlos Herrera-Úbeda, Pol Cuscó, Rafael Falcón-Moya, Antonio Rodríguez-Moreno, Salvatore D’Aniello, Bru Cormand, Gemma Marfany, Eduardo Soriano, Ángel M. Carrión, Jaime J. Carvajal, Jordi Garcia-Fernàndez
Genome Biol. 2020; 21: 267. Published online 2020 Oct 26. doi: 10.1186/s13059-020-02172-3
PMCID:
PMC7586669
AbstractArticlePDF–1.8M
15.
Inflammatory Signals Induce AT2 Cell-Derived Damage-Associated Transient Progenitors that Mediate Alveolar Regeneration
Jinwook Choi, Jong-Eun Park, Georgia Tsagkogeorga, Motoko Yanagita, Bon-Kyoung Koo, Namshik Han, Joo-Hyeon Lee
Cell Stem Cell. 2020 Sep 3; 27(3): 366–382.e7. doi: 10.1016/j.stem.2020.06.020
PMCID:
PMC7487779
AbstractArticle
16.
NDRG1 activates VEGF-A-induced angiogenesis through PLCγ1/ERK signaling in mouse vascular endothelial cells
Kosuke Watari, Tomohiro Shibata, Hideaki Fujita, Ai Shinoda, Yuichi Murakami, Hideyuki Abe, Akihiko Kawahara, Hiroshi Ito, Jun Akiba, Shigeo Yoshida, Michihiko Kuwano, Mayumi Ono
Commun Biol. 2020; 3: 107. Published online 2020 Mar 6. doi: 10.1038/s42003-020-0829-0
PMCID:
PMC7060337
AbstractArticlePDF–3.3M
17.
Protein O-GlcNAcylation Is Essential for the Maintenance of Renal Energy Homeostasis and Function via Lipolysis during Fasting and Diabetes
Sho Sugahara, Shinji Kume, Masami Chin-Kanasaki, Issei Tomita, Mako Yasuda-Yamahara, Kosuke Yamahara, Naoko Takeda, Norihisa Osawa, Motoko Yanagita, Shin-ichi Araki, Hiroshi Maegawa
J Am Soc Nephrol. 2019 Jun; 30(6): 962–978. Published online 2019 May 1. doi: 10.1681/ASN.2018090950
PMCID:
PMC6551777
AbstractArticle
18.
Transformation of the Transcriptomic Profile of Mouse Periocular Mesenchyme During Formation of the Embryonic Cornea
Justin Ma, Peter Lwigale
Invest Ophthalmol Vis Sci. 2019 Feb; 60(2): 661–676. doi: 10.1167/iovs.18-26018
PMCID:
PMC6383728
AbstractArticlePDF–2.1M
19.
Single-cell transcriptomic analysis of mouse neocortical development
Lipin Loo, Jeremy M. Simon, Lei Xing, Eric S. McCoy, Jesse K. Niehaus, Jiami Guo, E. S. Anton, Mark J. Zylka
Nat Commun. 2019; 10: 134. Published online 2019 Jan 11. doi: 10.1038/s41467-018-08079-9
PMCID:
PMC6329831
AbstractArticlePDF–3.6M
20.
Circulating FABP4 is eliminated by the kidney via glomerular filtration followed by megalin-mediated reabsorption
Suman Shrestha, Hiroaki Sunaga, Hirofumi Hanaoka, Aiko Yamaguchi, Shoji Kuwahara, Yogi Umbarawan, Kiyomi Nakajima, Tetsuo Machida, Masami Murakami, Akihiko Saito, Yoshito Tsushima, Masahiko Kurabayashi, Tatsuya Iso
Sci Rep. 2018; 8: 16451. Published online 2018 Nov 6. doi: 10.1038/s41598-018-34902-w
PMCID:
PMC6219568
AbstractArticlePDF–1.4M

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