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Select item 114113391.

In vitro differentiation of mouse pluripotent stem cells into corticosteroid-producing adrenocortical cells

Ioannis Oikonomakos, Melina Tedesco, Fariba Jian Motamedi, Mirko Peitzsch, Serge Nef, Stefan R. Bornstein, Andreas Schedl, Charlotte Steenblock, Yasmine Neirijnck

Stem Cell Reports. 2024 Sep 10; 19(9): 1289–1303. Published online 2024 Aug 22. doi: 10.1016/j.stemcr.2024.07.010

PMCID:: PMC11411339

Abstract Article PDF–5.7M

Select item 112508432.

Single-cell multiomics reveals ENL mutation perturbs kidney developmental trajectory by rewiring gene regulatory landscape

Lele Song, Qinglan Li, Lingbo Xia, Arushi Eesha Sahay, Qi Qiu, Yuanyuan Li, Haitao Li, Kotaro Sasaki, Katalin Susztak, Hao Wu, Liling Wan

Nat Commun. 2024; 15: 5937. Published online 2024 Jul 15. doi: 10.1038/s41467-024-50171-w

PMCID:: PMC11250843

Abstract Article PDF–12M

Select item 110684083.

Wnt signaling regulates ion channel expression to promote smooth muscle and cartilage formation in developing mouse trachea

Nicholas X. Russell, Kaulini Burra, Ronak M. Shah, Natalia Bottasso-Arias, Megha Mohanakrishnan, John Snowball, Harshavardhana H. Ediga, Satish K. Madala, Debora Sinner

Am J Physiol Lung Cell Mol Physiol. 2023 Dec 1; 325(6): L788–L802. Published online 2023 Oct 24. doi: 10.1152/ajplung.00024.2023

PMCID:: PMC11068408

Abstract Article

Select item 109858384.

MAP3K1 regulates female reproductive tract development

Eiki Kimura, Maureen Mongan, Bo Xiao, Antonius Christianto, Jingjing Wang, Vinicius S. Carreira, Brad Bolon, Xiang Zhang, Katherine A. Burns, Jacek Biesiada, Mario Medvedovic, Alvaro Puga, Ying Xia

Dis Model Mech. 2024 Mar 1; 17(3): dmm050669. Published online 2024 Mar 28. doi: 10.1242/dmm.050669

PMCID:: PMC10985838

Abstract Article

Select item 109427715.

Origin, specification and differentiation of a rare supporting-like lineage in the developing mouse gonad

Chloé Mayère, Violaine Regard, Aitana Perea-Gomez, Corey Bunce, Yasmine Neirijnck, Cyril Djari, Natividad Bellido-Carreras, Pauline Sararols, Richard Reeves, Simon Greenaway, Michelle Simon, Pam Siggers, Diana Condrea, Françoise Kühne, Ivana Gantar, Furong Tang, Isabelle Stévant, Laura Batti, Norbert B. Ghyselinck, Dagmar Wilhelm, Andy Greenfield, Blanche Capel, Marie-Christine Chaboissier, Serge Nef

Sci Adv. 2022 May; 8(21): eabm0972. Published online 2022 May 25. doi: 10.1126/sciadv.abm0972

PMCID:: PMC10942771

Abstract Article PDF–6.7M

Select item 108767036.

TEA domain transcription factor 1 (TEAD1) induces cardiac fibroblasts cells remodeling through BRD4/Wnt4 pathway

Shuai Song, Xiaokai Zhang, Zihang Huang, Yongchao Zhao, Shuyang Lu, Linqi Zeng, Fengze Cai, Tongyao Wang, Zhiqiang Pei, Xinyu Weng, Wei Luo, Hao Lu, Zilun Wei, Jian Wu, Peng Yu, Li Shen, Xiaochun Zhang, Aijun Sun, Junbo Ge

Signal Transduct Target Ther. 2024; 9: 45. Published online 2024 Feb 19. doi: 10.1038/s41392-023-01732-w

PMCID:: PMC10876703

Abstract Article PDF–6.0M

Select item 108614707.

A common allele increases endometrial Wnt4 expression, with antagonistic implications for pregnancy, reproductive cancers, and endometriosis

Mihaela Pavličev, Caitlin E. McDonough-Goldstein, Andreja Moset Zupan, Lisa Muglia, Yueh-Chiang Hu, Fansheng Kong, Nagendra Monangi, Gülay Dagdas, Nina Zupančič, Jamie Maziarz, Debora Sinner, Ge Zhang, Günter Wagner, Louis Muglia

Nat Commun. 2024; 15: 1152. Published online 2024 Feb 12. doi: 10.1038/s41467-024-45338-4

PMCID:: PMC10861470

Abstract Article PDF–2.8M

Select item 107535878.

Loss of NR5A1 in mouse Sertoli cells after sex determination changes cellular identity and induces cell death by anoikis

Sirine Souali-Crespo, Diana Condrea, Nadège Vernet, Betty Féret, Muriel Klopfenstein, Erwan Grandgirard, Violaine Alunni, Marie Cerciat, Matthieu Jung, Chloé Mayere, Serge Nef, Manuel Mark, Frédéric Chalmel, Norbert B. Ghyselinck

Development. 2023 Dec 15; 150(24): dev201710. Published online 2023 Dec 11. doi: 10.1242/dev.201710

PMCID:: PMC10753587

Abstract Article

Select item 106763609.

Acetyl-CoA is a key molecule for nephron progenitor cell pool maintenance

Fabiola Diniz, Nguyen Yen Nhi Ngo, Mariel Colon-Leyva, Francesca Edgington-Giordano, Sylvia Hilliard, Kevin Zwezdaryk, Jiao Liu, Samir S. El-Dahr, Giovane G. Tortelote

Nat Commun. 2023; 14: 7733. Published online 2023 Nov 25. doi: 10.1038/s41467-023-43513-7

PMCID:: PMC10676360

Abstract Article PDF–12M

Select item 1057727810.

Rhox8 homeobox gene ablation leads to rete testis abnormality and male subfertility in mice

Yeongseok Oh, Maho Kasu, Constence J Bottoms, Jenna C Douglas, Nikola Sekulovski, Kanako Hayashi, James A MacLean II

Biol Reprod. 2023 Oct; 109(4): 520–532. Published online 2023 Jul 20. doi: 10.1093/biolre/ioad077

PMCID:: PMC10577278

Abstract Article PDF–1.9M

Select item 1054730011.

Crk and Crkl Are Required in the Endocardial Lineage for Heart Valve Development

Bingruo Wu, Brian Wu, Sonia Benkaci, Lijie Shi, Pengfei Lu, Taeju Park, Bernice E. Morrow, Yidong Wang, Bin Zhou

J Am Heart Assoc. 2023 Sep 19; 12(18): e029683. Published online 2023 Sep 13. doi: 10.1161/JAHA.123.029683

PMCID:: PMC10547300

Abstract Article PDF–41M

Select item 1050641312.

Smarca4 deficiency induces Pttg1 oncogene upregulation and hyperproliferation of tubular and interstitial cells during kidney development

Jinshu Xu, Xianxiao Zhou, Ting Zhang, Bin Zhang, Pin-Xian Xu

Front Cell Dev Biol. 2023; 11: 1233317. Published online 2023 Sep 4. doi: 10.3389/fcell.2023.1233317

PMCID:: PMC10506413

Abstract Article PDF–7.2M

Select item 1048238713.

A WNT4- and DKK3-driven canonical to noncanonical Wnt signaling switch controls multiciliogenesis

Riley A. Cooney, Maxwell L. Saal, Kara P. Geraci, Caitlin Maynard, Ondine Cleaver, Oanh N. Hoang, Todd T. Moore, Rosa F. Hwang, Jeffrey D. Axelrod, Eszter K. Vladar

J Cell Sci. 2023 Aug 15; 136(16): jcs260807. Published online 2023 Aug 29. doi: 10.1242/jcs.260807

PMCID:: PMC10482387

Abstract Article

Select item 1047875414.

CHARGE syndrome-associated CHD7 acts at ISL1-regulated enhancers to modulate second heart field gene expression

Athanasia Stathopoulou, Ping Wang, Charlotte Thellier, Robert G Kelly, Deyou Zheng, Peter J Scambler

Cardiovasc Res. 2023 Aug; 119(11): 2089–2105. Published online 2023 Apr 13. doi: 10.1093/cvr/cvad059

Correction in:: Cardiovasc Res. 2024 Jan; 120(1): 120.

PMCID:: PMC10478754

Abstract Article PDF–21M

Select item 1039049215.

Three-dimensional molecular architecture of mouse organogenesis

Fangfang Qu, Wenjia Li, Jian Xu, Ruifang Zhang, Jincan Ke, Xiaodie Ren, Xiaogao Meng, Lexin Qin, Jingna Zhang, Fangru Lu, Xin Zhou, Xi Luo, Zhen Zhang, Minhan Wang, Guangming Wu, Duanqing Pei, Jiekai Chen, Guizhong Cui, Shengbao Suo, Guangdun Peng

Nat Commun. 2023; 14: 4599. Published online 2023 Jul 31. doi: 10.1038/s41467-023-40155-7

PMCID:: PMC10390492

Abstract Article PDF–13M

Select item 1029215716.

A Wnt-Bmp Feedback Circuit Controls Intertissue Signaling Dynamics in Tooth Organogenesis

Daniel J. O’Connell, Joshua W. K. Ho, Tadanori Mammoto, Annick Turbe-Doan, Joyce T. O’Connell, Psalm S. Haseley, Samuel Koo, Nobuhiro Kamiya, Donald E. Ingber, Peter J. Park, Richard L. Maas

Sci Signal. Author manuscript; available in PMC 2023 Jun 26.

Published in final edited form as: Sci Signal. 2012 Jan 10; 5(206): ra4. Published online 2012 Jan 10. doi: 10.1126/scisignal.2002414

PMCID:: PMC10292157

Abstract Article PDF–1.0M

Select item 1028175117.

SOX7 deficiency causes ventricular septal defects through its effects on endocardial-to-mesenchymal transition and the expression of Wnt4 and Bmp2

Andrés Hernández-García, Katherine E Pendleton, Sangbae Kim, Yumei Li, Bum J Kim, Hitisha P Zaveri, Valerie K Jordan, Aliska M Berry, M Cecilia Ljungberg, Rui Chen, Rainer B Lanz, Daryl A Scott

Hum Mol Genet. 2023 Jul 1; 32(13): 2152–2161. Published online 2023 Mar 31. doi: 10.1093/hmg/ddad050

PMCID:: PMC10281751

Abstract Article PDF–1.6M

Select item 1019393718.

CDYL reinforces male gonadal sex determination through epigenetically repressing Wnt4 transcription in mice

Naoki Okashita, Ryo Maeda, Makoto Tachibana

Proc Natl Acad Sci U S A. 2023 May 16; 120(20): e2221499120. Published online 2023 May 8. doi: 10.1073/pnas.2221499120

PMCID:: PMC10193937

Abstract Article PDF–1.9M

Select item 1013407319.

Graded BMP Signaling Within Intestinal Crypt Architecture Directs Self-organization of the Wnt-secreting Stem Cell Niche

Judith Kraiczy, Neil McCarthy, Ermanno Malagola, Guodong Tie, Shariq Madha, Dario Boffelli, Daniel E. Wagner, Timothy C. Wang, Ramesh A. Shivdasani

Cell Stem Cell. Author manuscript; available in PMC 2024 Apr 6.

Published in final edited form as: Cell Stem Cell. 2023 Apr 6; 30(4): 433–449.e8. doi: 10.1016/j.stem.2023.03.004

PMCID:: PMC10134073

Abstract Article PDF–5.1M

Select item 1011292320.

Loss of WNT4 in the gubernaculum causes unilateral cryptorchidism and fertility defects

Abhishek Seth, Juan C. Bournat, Olga Medina-Martinez, Armando Rivera, Joshua Moore, Hunter Flores, Jill A. Rosenfeld, Liya Hu, Carolina J. Jorgez

Development. 2022 Dec 1; 149(23): dev201093. Published online 2022 Nov 30. doi: 10.1242/dev.201093

PMCID:: PMC10112923

Abstract Article

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