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Select item 110314271.

Oncostatin M signaling drives cancer-associated skeletal muscle wasting

Aylin Domaniku-Waraich, Samet Agca, Batu Toledo, Melis Sucuoglu, Sevgi Döndü Özen, Sevval Nur Bilgic, Dilsad Hilal Arabaci, Aynur Erkin Kashgari, Serkan Kir

Cell Rep Med. 2024 Apr 16; 5(4): 101498. Published online 2024 Apr 4. doi: 10.1016/j.xcrm.2024.101498

PMCID:: PMC11031427

Abstract Article PDF–4.2M

Select item 109176602.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 109122913.

Oncostatin M: Dual Regulator of the Skeletal and Hematopoietic Systems

Natalie A. Sims, Jean-Pierre Lévesque

Curr Osteoporos Rep. 2024; 22(1): 80–95. Published online 2024 Jan 10. doi: 10.1007/s11914-023-00837-z

PMCID:: PMC10912291

Abstract Article PDF–2.1M

Select item 108612124.

Network‐based cytokine inference implicates Oncostatin M as a driver of an inflammation phenotype in knee osteoarthritis

Hirotaka Iijima, Fan Zhang, Fabrisia Ambrosio, Yusuke Matsui

Aging Cell. 2024 Feb; 23(2): e14043. Published online 2023 Dec 18. doi: 10.1111/acel.14043

PMCID:: PMC10861212

Abstract Article PDF–20M

Select item 107778765.

Oncostatin M Reduces Pathological Neovascularization in the Retina Through Müller Cell Activation

Julian Rapp, Alban Hospach, Paula Liang, Melanie Schwämmle, Lisa Renz, Hansjürgen Agostini, Günther Schlunck, Felicitas Bucher

Invest Ophthalmol Vis Sci. 2024 Jan; 65(1): 22. Published online 2024 Jan 8. doi: 10.1167/iovs.65.1.22

PMCID:: PMC10777876

Abstract Article PDF–5.8M

Select item 89706786.

Stromal oncostatin M cytokine promotes breast cancer progression by reprogramming the tumor microenvironment

Angela M. Araujo, Andrea Abaurrea, Peio Azcoaga, Joanna I. López-Velazco, Sara Manzano, Javier Rodriguez, Ricardo Rezola, Leire Egia-Mendikute, Fátima Valdés-Mora, Juana M. Flores, Liam Jenkins, Laura Pulido, Iñaki Osorio-Querejeta, Patricia Fernández-Nogueira, Nicola Ferrari, Cristina Viera, Natalia Martín-Martín, Alexandar Tzankov, Serenella Eppenberger-Castori, Isabel Alvarez-Lopez, Ander Urruticoechea, Paloma Bragado, Nicholas Coleman, Asís Palazón, Arkaitz Carracedo, David Gallego-Ortega, Fernando Calvo, Clare M. Isacke, María M. Caffarel, Charles H. Lawrie

J Clin Invest. 2022 Apr 1; 132(7): e148667. Published online 2022 Apr 1. doi: 10.1172/JCI148667

Correction in:: J Clin Invest. 2022 Oct 3; 132(19): e165107.

PMCID:: PMC8970678

Abstract Article PDF–13M

Select item 89532537.

Stimulation of Osteoclast Formation by Oncostatin M and the Role of WNT16 as a Negative Feedback Regulator

Pedro P. C. de Souza, Petra Henning, Ulf H. Lerner

Int J Mol Sci. 2022 Mar; 23(6): 3287. Published online 2022 Mar 18. doi: 10.3390/ijms23063287

PMCID:: PMC8953253

Abstract Article PDF–2.0M

Select item 87455628.

Concomitant Activation of OSM and LIF Receptor by a Dual-Specific hlOSM Variant Confers Cardioprotection after Myocardial Infarction in Mice

Holger Lörchner, Juan M. Adrian-Segarra, Christian Waechter, Roxanne Wagner, Maria Elisa Góes, Nathalie Brachmann, Krishnamoorthy Sreenivasan, Astrid Wietelmann, Stefan Günther, Nicolas Doll, Thomas Braun, Jochen Pöling

Int J Mol Sci. 2022 Jan; 23(1): 353. Published online 2021 Dec 29. doi: 10.3390/ijms23010353

PMCID:: PMC8745562

Abstract Article PDF–4.3M

Select item 86834369.

Heterocellular OSM-OSMR signalling reprograms fibroblasts to promote pancreatic cancer growth and metastasis

Brian Y. Lee, Elizabeth K. J. Hogg, Christopher R. Below, Alexander Kononov, Adrian Blanco-Gomez, Felix Heider, Jingshu Xu, Colin Hutton, Xiaohong Zhang, Tamara Scheidt, Kenneth Beattie, Angela Lamarca, Mairéad McNamara, Juan W. Valle, Claus Jørgensen

Nat Commun. 2021; 12: 7336. Published online 2021 Dec 17. doi: 10.1038/s41467-021-27607-8

PMCID:: PMC8683436

Abstract Article PDF–6.4M

Select item 858422110.

Murine Oncostatin M Has Opposing Effects on the Proliferation of OP9 Bone Marrow Stromal Cells and NIH/3T3 Fibroblasts Signaling through the OSMR

Lena Jakob, Tony Andreas Müller, Michael Rassner, Helen Kleinfelder, Pia Veratti, Jan Mitschke, Cornelius Miething, Robert A. J. Oostendorp, Dietmar Pfeifer, Miguel Waterhouse, Justus Duyster

Int J Mol Sci. 2021 Nov; 22(21): 11649. Published online 2021 Oct 28. doi: 10.3390/ijms222111649

PMCID:: PMC8584221

Abstract Article PDF–1.5M

Select item 850277511.

Oncostatin M suppresses browning of white adipocytes via gp130-STAT3 signaling

Pim P. van Krieken, Timothy S. Odermatt, Marcela Borsigova, Matthias Blüher, Stephan Wueest, Daniel Konrad

Mol Metab. 2021 Dec; 54: 101341. Published online 2021 Sep 20. doi: 10.1016/j.molmet.2021.101341

PMCID:: PMC8502775

Abstract Article PDF–1.0M

Select item 809096112.

Neutrophil-Derived Oncostatin M Triggers Diverse Signaling Pathways during Pneumonia

Katrina E. Traber, Ernest L. Dimbo, Anukul T. Shenoy, Elise M. Symer, Eri Allen, Joseph P. Mizgerd, Lee J. Quinton

Infect Immun. 2021 Apr; 89(4): e00655-20. Prepublished online 2021 Feb 1. Published online 2021 Mar 17. doi: 10.1128/IAI.00655-20

PMCID:: PMC8090961

Abstract Article PDF–1.5M

Select item 734935013.

RELMα Is Induced in Airway Epithelial Cells by Oncostatin M without Requirement of STAT6 or IL-6 in Mouse Lungs In Vivo

Lilian Ho, Ashley Yip, Francis Lao, Fernando Botelho, Carl D. Richards

Cells. 2020 Jun; 9(6): 1338. Published online 2020 May 27. doi: 10.3390/cells9061338

PMCID:: PMC7349350

Abstract Article PDF–6.1M

Select item 679361514.

Loss of Leukemia Inhibitory Factor Receptor β or Cardiotrophin-1 Causes Similar Deficits in Preganglionic Sympathetic Neurons and Adrenal Medulla

Stephan Oberle, Andreas Schober, Verena Meyer, Bettina Holtmann, Christopher Henderson, Michael Sendtner, Klaus Unsicker

J Neurosci. 2006 Feb 8; 26(6): 1823–1832. doi: 10.1523/JNEUROSCI.4127-05.2006

PMCID:: PMC6793615

Abstract Article PDF–741K

Select item 673041315.

Essential Function of Oncostatin M in Nociceptive Neurons of Dorsal Root Ganglia

Yoshihiro Morikawa, Shinobu Tamura, Ken-ichi Minehata, Peter J. Donovan, Atsushi Miyajima, Emiko Senba

J Neurosci. 2004 Feb 25; 24(8): 1941–1947. doi: 10.1523/JNEUROSCI.4975-03.2004

PMCID:: PMC6730413

Abstract Article PDF–534K

Select item 671338616.

Oncostatin M reduces atherosclerosis development in APOE*3Leiden.CETP mice and is associated with increased survival probability in humans

Danielle van Keulen, Marianne G. Pouwer, Valur Emilsson, Ljubica Perisic Matic, Elsbet J. Pieterman, Ulf Hedin, Vilmundur Gudnason, Lori L. Jennings, Kim Holmstrøm, Boye Schnack Nielsen, Gerard Pasterkamp, Jan H. N. Lindeman, Alain J. van Gool, Maarten D. Sollewijn Gelpke, Hans M. G. Princen, Dennie Tempel

PLoS One. 2019; 14(8): e0221477. Published online 2019 Aug 28. doi: 10.1371/journal.pone.0221477

PMCID:: PMC6713386

Abstract Article PDF–4.2M

Select item 659778817.

Macrophage hypoxia signaling regulates cardiac fibrosis via Oncostatin M

Hajime Abe, Norihiko Takeda, Takayuki Isagawa, Hiroaki Semba, Satoshi Nishimura, Masaki Suimye Morioka, Yu Nakagama, Tatsuyuki Sato, Katsura Soma, Katsuhiro Koyama, Masaki Wake, Manami Katoh, Masataka Asagiri, Michael L. Neugent, Jung-whan Kim, Christian Stockmann, Tomo Yonezawa, Ryo Inuzuka, Yasushi Hirota, Koji Maemura, Takeshi Yamashita, Kinya Otsu, Ichiro Manabe, Ryozo Nagai, Issei Komuro

Nat Commun. 2019; 10: 2824. Published online 2019 Jun 27. doi: 10.1038/s41467-019-10859-w

PMCID:: PMC6597788

Abstract Article PDF–1.0M

Select item 640670018.

Extracellular Matrix and Fibrocyte Accumulation in BALB/c Mouse Lung upon Transient Overexpression of Oncostatin M

Fernando M. Botelho, Rebecca Rodrigues, Jessica Guerette, Steven Wong, Dominik K. Fritz, Carl D. Richards

Cells. 2019 Feb; 8(2): 126. Published online 2019 Feb 5. doi: 10.3390/cells8020126

PMCID:: PMC6406700

Abstract Article PDF–2.0M

Select item 634119119.

Endothelial signaling by neutrophil-released oncostatin M enhances P-selectin–dependent inflammation and thrombosis

Hendra Setiadi, Tadayuki Yago, Zhenghui Liu, Rodger P. McEver

Blood Adv. 2019 Jan 22; 3(2): 168–183. Published online 2019 Jan 22. doi: 10.1182/bloodadvances.2018026294

PMCID:: PMC6341191

Abstract Article PDF–2.0M

Select item 631152020.

The AB loop of oncostatin M (OSM) determines species-specific signaling in humans and mice

Juan M. Adrian-Segarra, Krishnamoorthy Sreenivasan, Praveen Gajawada, Holger Lörchner, Thomas Braun, Jochen Pöling

J Biol Chem. 2018 Dec 28; 293(52): 20181–20199. Published online 2018 Oct 29. doi: 10.1074/jbc.RA118.004375

PMCID:: PMC6311520

Abstract Article PDF–6.9M

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