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Select item 109425761.

Delta-dependent Notch activation closes the early neuroblast temporal program to promote lineage progression and neurogenesis termination in Drosophila

Chhavi Sood, Md Ausrafuggaman Nahid, Kendall R Branham, Matt Pahl, Susan E Doyle, Sarah E Siegrist

eLife. 2024; 12: RP88565. Published online 2024 Feb 23. doi: 10.7554/eLife.88565

PMCID:: PMC10942576

Abstract Article PDF–7.0M

Select item 106219952.

A novel proneural function of Asense is integrated with the sequential actions of Delta-Notch, L’sc and Su(H) to promote the neuroepithelial to neuroblast transition

Mercedes Martin, Francisco Gutierrez-Avino, Mirja N. Shaikh, Francisco J. Tejedor

PLoS Genet. 2023 Oct; 19(10): e1010991. Published online 2023 Oct 23. doi: 10.1371/journal.pgen.1010991

PMCID:: PMC10621995

Abstract Article PDF–6.9M

Select item 104388403.

Growth deregulation and interaction with host hemocytes contribute to tumor progression in a Drosophila brain tumor model

Chrysanthi Voutyraki, Alexandros Choromidis, Anastasia Meligkounaki, Nikolaos Andreas Vlachopoulos, Vasiliki Theodorou, Sofia Grammenoudi, Emmanouil Athanasiadis, Sara Monticelli, Angela Giangrande, Christos Delidakis, Evanthia Zacharioudaki

Proc Natl Acad Sci U S A. 2023 Aug 15; 120(33): e2221601120. Published online 2023 Aug 7. doi: 10.1073/pnas.2221601120

PMCID:: PMC10438840

Abstract Article PDF–4.3M

Select item 103444264.

Low-level repressive histone marks fine-tune gene transcription in neural stem cells

Arjun Rajan, Lucas Anhezini, Noemi Rives-Quinto, Jay Y Chhabra, Megan C Neville, Elizabeth D Larson, Stephen F Goodwin, Melissa M Harrison, Cheng-Yu Lee

eLife. 2023; 12: e86127. Published online 2023 Jun 14. doi: 10.7554/eLife.86127

PMCID:: PMC10344426

Abstract Article PDF–13M

Select item 103232355.

A chromatin remodelling SWI/SNF subunit, Snr1, regulates neural stem cell determination and differentiation

Sophie E. Keegan, Julie Haskins, Andrew J. Simmonds, Sarah C. Hughes

Development. 2023 Jul 1; 150(13): dev201484. Published online 2023 Jun 30. doi: 10.1242/dev.201484

PMCID:: PMC10323235

Abstract Article

Select item 101057366.

Next-generation large-scale binary protein interaction network for Drosophila melanogaster

Hong-Wen Tang, Kerstin Spirohn, Yanhui Hu, Tong Hao, István A. Kovács, Yue Gao, Richard Binari, Donghui Yang-Zhou, Kenneth H. Wan, Joel S. Bader, Dawit Balcha, Wenting Bian, Benjamin W. Booth, Atina G. Coté, Steffi de Rouck, Alice Desbuleux, Kah Yong Goh, Dae-Kyum Kim, Jennifer J. Knapp, Wen Xing Lee, Irma Lemmens, Cathleen Li, Mian Li, Roujia Li, Hyobin Julianne Lim, Yifang Liu, Katja Luck, Dylan Markey, Carl Pollis, Sudharshan Rangarajan, Jonathan Rodiger, Sadie Schlabach, Yun Shen, Dayag Sheykhkarimli, Bridget TeeKing, Frederick P. Roth, Jan Tavernier, Michael A. Calderwood, David E. Hill, Susan E. Celniker, Marc Vidal, Norbert Perrimon, Stephanie E. Mohr

Nat Commun. 2023; 14: 2162. Published online 2023 Apr 15. doi: 10.1038/s41467-023-37876-0

PMCID:: PMC10105736

Abstract Article PDF–3.2M

Select item 94271157.

A Notch-dependent transcriptional mechanism controls expression of temporal patterning factors in Drosophila medulla

Alokananda Ray, Xin Li

eLife. 2022; 11: e75879. Published online 2022 Aug 30. doi: 10.7554/eLife.75879

PMCID:: PMC9427115

Abstract Article PDF–32M

Select item 89188098.

Notch signaling regulates neural stem cell quiescence entry and exit in Drosophila

Chhavi Sood, Virginia T. Justis, Susan E. Doyle, Sarah E. Siegrist

Development. 2022 Feb 15; 149(4): dev200275. Published online 2022 Feb 18. doi: 10.1242/dev.200275

PMCID:: PMC8918809

Abstract Article

Select item 88809539.

Mitochondrial fusion regulates proliferation and differentiation in the type II neuroblast lineage in Drosophila

Dnyanesh Dubal, Prachiti Moghe, Rahul Kumar Verma, Bhavin Uttekar, Richa Rikhy

PLoS Genet. 2022 Feb; 18(2): e1010055. Published online 2022 Feb 14. doi: 10.1371/journal.pgen.1010055

PMCID:: PMC8880953

Abstract Article PDF–5.2M

Select item 865749210.

Regulation of Neural Stem Cell Competency and Commitment during Indirect Neurogenesis

Arjun Rajan, Cyrina M. Ostgaard, Cheng-Yu Lee

Int J Mol Sci. 2021 Dec; 22(23): 12871. Published online 2021 Nov 28. doi: 10.3390/ijms222312871

PMCID:: PMC8657492

Abstract Article PDF–1.5M

Select item 849422811.

A single-cell atlas reveals unanticipated cell type complexity in Drosophila ovaries

Maija Slaidina, Selena Gupta, Torsten U. Banisch, Ruth Lehmann

Genome Res. 2021 Oct; 31(10): 1938–1951. doi: 10.1101/gr.274340.120

PMCID:: PMC8494228

Abstract Article PDF–15M

Select item 789538412.

Homeodomain protein Six4 prevents the generation of supernumerary Drosophila type II neuroblasts and premature differentiation of intermediate neural progenitors

Rui Chen, Yanjun Hou, Marisa Connell, Sijun Zhu

PLoS Genet. 2021 Feb; 17(2): e1009371. Published online 2021 Feb 8. doi: 10.1371/journal.pgen.1009371

PMCID:: PMC7895384

Abstract Article PDF–9.1M

Select item 776826213.

The Broad Transcription Factor Links Hormonal Signaling, Gene Expression, and Cellular Morphogenesis Events During Drosophila Imaginal Disc Development

Clinton Rice, Stuart J. Macdonald, Xiaochen Wang, Robert E. Ward

Genetics. 2020 Dec; 216(4): 1137–1152. Published online 2020 Oct 28. doi: 10.1534/genetics.120.303717

PMCID:: PMC7768262

Abstract Article PDF–1.5M

Select item 755019214.

Topology-driven protein-protein interaction network analysis detects genetic sub-networks regulating reproductive capacity

Tarun Kumar, Leo Blondel, Cassandra G Extavour

eLife. 2020; 9: e54082. Published online 2020 Sep 9. doi: 10.7554/eLife.54082

PMCID:: PMC7550192

Abstract Article PDF–2.8M

Select item 748597615.

Sequential activation of Notch and Grainyhead gives apoptotic competence to Abdominal-B expressing larval neuroblasts in Drosophila Central nervous system

Asif Bakshi, Rashmi Sipani, Neha Ghosh, Rohit Joshi

PLoS Genet. 2020 Aug; 16(8): e1008976. Published online 2020 Aug 31. doi: 10.1371/journal.pgen.1008976

PMCID:: PMC7485976

Abstract Article PDF–7.3M

Select item 747962016.

Single-cell transcriptome maps of myeloid blood cell lineages in Drosophila

Bumsik Cho, Sang-Ho Yoon, Daewon Lee, Ferdinand Koranteng, Sudhir Gopal Tattikota, Nuri Cha, Mingyu Shin, Hobin Do, Yanhui Hu, Sue Young Oh, Daehan Lee, A. Vipin Menon, Seok Jun Moon, Norbert Perrimon, Jin-Wu Nam, Jiwon Shim

Nat Commun. 2020; 11: 4483. Published online 2020 Sep 8. doi: 10.1038/s41467-020-18135-y