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Select item 79387701.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 77904152.

Loss of endocytosis-associated RabGEF1 causes aberrant morphogenesis and altered autophagy in photoreceptors leading to retinal degeneration

Passley Hargrove-Grimes, Anupam K. Mondal, Jessica Gumerson, Jacob Nellissery, Angel M. Aponte, Linn Gieser, Haohua Qian, Robert N. Fariss, Juan S. Bonifacino, Tiansen Li, Anand Swaroop

PLoS Genet. 2020 Dec; 16(12): e1009259. Published online 2020 Dec 23. doi: 10.1371/journal.pgen.1009259

PMCID:: PMC7790415

Abstract Article PDF–4.4M

Select item 74159913.

BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)

Kou Motani, Hidetaka Kosako

J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323

PMCID:: PMC7415991

Abstract Article PDF–2.0M

Select item 61938724.

Rearrangement of the Protein Phosphatase 1 Interactome during Heart Failure Progression

David Y. Chiang, Katherina M. Alsina, Eleonora Corradini, Martin Fitzpatrick, Li Ni, Satadru K. Lahiri, Julia Reynolds, Xiaolu Pan, Larry Scott, Jr, Albert J.R. Heck, Xander H.T. Wehrens

Circulation. Author manuscript; available in PMC 2019 Oct 9.

Published in final edited form as: Circulation. 2018 Oct 9; 138(15): 1569–1581. doi: 10.1161/CIRCULATIONAHA.118.034361

PMCID:: PMC6193872

Abstract Article PDF–2.4M

Select item 57800415.

Endosomal Rab cycles regulate Parkin-mediated mitophagy

Koji Yamano, Chunxin Wang, Shireen A Sarraf, Christian Münch, Reika Kikuchi, Nobuo N Noda, Yohei Hizukuri, Masato T Kanemaki, Wade Harper, Keiji Tanaka, Noriyuki Matsuda, Richard J Youle

eLife. 2018; 7: e31326. Published online 2018 Jan 23. doi: 10.7554/eLife.31326

PMCID:: PMC5780041

Abstract Article PDF–11M

Select item 56450826.

Spatio-temporal profile of postynaptic interactomes integrates components of complex brain disorders

Jing Li, Wangshu Zhang, Hui Yang, Daniel P. Howrigan, Brent Wilkinson, Tade Souaiaia, Oleg V. Evgrafov, Giulio Genovese, Veronica A. Clementel, Jennifer C. Tudor, Ted Abel, James A. Knowles, Benjamin M. Neale, Kai Wang, Fengzhu Sun, Marcelo P. Coba

Nat Neurosci. Author manuscript; available in PMC 2018 Aug 1.

Published in final edited form as: Nat Neurosci. 2017 Aug; 20(8): 1150–1161. Published online 2017 Jun 26. doi: 10.1038/nn.4594

PMCID:: PMC5645082

Abstract Article PDF–2.3M

Select item 51348937.

Variants of Rab GTPase-effector binding protein-2 cause variation in the collateral circulation and severity of stroke

Jennifer L. Lucitti, Robert Sealock, Brian K. Buckley, Hua Zhang, Lin Xiao, Andrew C. Dudley, James E. Faber

Stroke. Author manuscript; available in PMC 2017 Dec 1.

Published in final edited form as: Stroke. 2016 Dec; 47(12): 3022–3031. Published online 2016 Nov 3. doi: 10.1161/STROKEAHA.116.014160

PMCID:: PMC5134893

Abstract Article PDF–1.0M

Select item 51276798.

Guanine nucleotide exchange factor RABGEF1 regulates keratinocyte-intrinsic signaling to maintain skin homeostasis

Thomas Marichal, Nicolas Gaudenzio, Sophie El Abbas, Riccardo Sibilano, Oliwia Zurek, Philipp Starkl, Laurent L. Reber, Dimitri Pirottin, Jinah Kim, Pierre Chambon, Axel Roers, Nadine Antoine, Yuko Kawakami, Toshiaki Kawakami, Fabrice Bureau, See-Ying Tam, Mindy Tsai, Stephen J. Galli

J Clin Invest. 2016 Dec 1; 126(12): 4497–4515. Published online 2016 Nov 7. doi: 10.1172/JCI86359

PMCID:: PMC5127679

Abstract Article PDF–6.9M

Select item 50358839.

Rabex-5 is a lenalidomide target molecule that negatively regulates TLR-induced type 1 IFN production

David Millrine, Mami Tei, Yohannes Gemechu, Tadamitsu Kishimoto

Proc Natl Acad Sci U S A. 2016 Sep 20; 113(38): 10625–10630. Published online 2016 Sep 6. doi: 10.1073/pnas.1611751113

PMCID:: PMC5035883

Abstract Article PDF–1020K

Select item 494415810.

AP-1/σ1A and AP-1/σ1B adaptor-proteins differentially regulate neuronal early endosome maturation via the Rab5/Vps34-pathway

Ermes Candiello, Manuel Kratzke, Dirk Wenzel, Dan Cassel, Peter Schu

Sci Rep. 2016; 6: 29950. Published online 2016 Jul 14. doi: 10.1038/srep29950

PMCID:: PMC4944158

Abstract Article PDF–1.4M

Select item 424522611.

RABEX-5 Is Upregulated and Plays an Oncogenic Role in Gastric Cancer Development by Activating the VEGF Signaling Pathway

Shuang Wang, Aixia Lu, Xiangming Chen, Lin Wei, Jiqiang Ding

PLoS One. 2014; 9(11): e113891. Published online 2014 Nov 26. doi: 10.1371/journal.pone.0113891

PMCID:: PMC4245226

Abstract Article PDF–12M

Select item 413857912.

Rab5 Activity Regulates GLUT4 Sorting Into Insulin-Responsive and Non-Insulin-Responsive Endosomal Compartments: A Potential Mechanism for Development of Insulin Resistance

Kandice L. Tessneer, Robert M. Jackson, Beth A. Griesel, Ann Louise Olson

Endocrinology. 2014 Sep; 155(9): 3315–3328. Published online 2014 Jun 16. doi: 10.1210/en.2013-2148

PMCID:: PMC4138579

Abstract Article

Select item 369762013.

Regulation of Rab5 Function during Phagocytosis of Live Pseudomonas aeruginosa in Macrophages

Sushmita Mustafi, Nathalie Rivero, Joan C. Olson, Philip D. Stahl, M. Alejandro Barbieri

Infect Immun. 2013 Jul; 81(7): 2426–2436. doi: 10.1128/IAI.00387-13

PMCID:: PMC3697620

Abstract Article PDF–1.1M

Select item 362739914.

Klf5 controls bone marrow homing of stem cells and progenitors through Rab5-mediated ß1/ß2-integrin trafficking

E. Taniguchi Ishikawa, K.H. Chang, R. Nayak, H.A Olsson, A. Ficker, S.K. Dunn, M. Madhu, A. Sengupta, J.A. Whitsett, H.L. Grimes, J.A. Cancelas

Nat Commun. Author manuscript; available in PMC 2013 Oct 3.

Published in final edited form as: Nat Commun. 2013; 4: 1660. doi: 10.1038/ncomms2645

PMCID:: PMC3627399

Abstract Article PDF–1.1M

Select item 361728415.

Rabex-5 Protein Regulates Dendritic Localization of Small GTPase Rab17 and Neurite Morphogenesis in Hippocampal Neurons

Yasunori Mori, Takahide Matsui, Mitsunori Fukuda

J Biol Chem. 2013 Apr 5; 288(14): 9835–9847. Published online 2013 Feb 19. doi: 10.1074/jbc.M112.427591

PMCID:: PMC3617284

Abstract Article PDF–3.1M

Select item 346331016.

Rabex-5 Protein Regulates the Endocytic Trafficking Pathway of Ubiquitinated Neural Cell Adhesion Molecule L1

Yoshikatsu Aikawa

J Biol Chem. 2012 Sep 21; 287(39): 32312–32323. Published online 2012 Jul 30. doi: 10.1074/jbc.M112.374322

PMCID:: PMC3463310

Abstract Article PDF–2.6M

Select item 317805917.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 296679918.

Thymic Stromal Lymphopoietin Contributes to Myeloid Hyperplasia and Increased Immunoglobulins, But Not Epidermal Hyperplasia, in RabGEF1-Deficient Mice

Mindy Tsai, Ching-Cheng Chen, Kaori Mukai, Chang Ho Song, Lucas J. Thompson, Steven F. Ziegler, See-Ying Tam, Stephen J. Galli

Am J Pathol. 2010 Nov; 177(5): 2411–2420. doi: 10.2353/ajpath.2010.100181

PMCID:: PMC2966799

Abstract Article PDF–1.4M

Select item 282191619.

Delayed Onset of Positive Feedback Activation of Rab5 by Rabex-5 and Rabaptin-5 in Endocytosis

Huaiping Zhu, Hong Qian, Guangpu Li

PLoS One. 2010; 5(2): e9226. Published online 2010 Feb 16. doi: 10.1371/journal.pone.0009226

PMCID:: PMC2821916

Abstract Article PDF–709K

Select item 277710220.

Rabex-5 Is a Rab22 Effector and Mediates a Rab22-Rab5 Signaling Cascade in Endocytosis

Huaiping Zhu, Zhimin Liang, Guangpu Li

Mol Biol Cell. 2009 Nov 15; 20(22): 4720–4729. doi: 10.1091/mbc.E09-06-0453

PMCID:: PMC2777102

Abstract Article PDF–1.4M

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