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Select item 103943311.

Tripartite motif 38 alleviates the pathological process of NAFLD–NASH by promoting TAB2 degradation

Xinxin Yao, Ruixiang Dong, Sha Hu, Zhen Liu, Jie Cui, Fengjiao Hu, Xu Cheng, Xiaoming Wang, Tengfei Ma, Song Tian, Xiao-Jing Zhang, Yufeng Hu, Lan Bai, Hongliang Li, Peng Zhang

J Lipid Res. 2023 Jul; 64(7): 100382. Published online 2023 Apr 26. doi: 10.1016/j.jlr.2023.100382

PMCID:: PMC10394331

Abstract Article PDF–3.1M

Select item 100704382.

E3 ligase RNF99 negatively regulates TLR-mediated inflammatory immune response via K48-linked ubiquitination of TAB2

Jie Zhang, Lei Cao, Amy Gao, Ruiqing Ren, Liwen Yu, Qian Li, Yapeng Liu, Wenqian Qi, Yonghao Hou, Wenhai Sui, Guohai Su, Yun Zhang, Cheng Zhang, Meng Zhang

Cell Death Differ. 2023 Apr; 30(4): 966–978. Published online 2023 Jan 21. doi: 10.1038/s41418-023-01115-2

PMCID:: PMC10070438

Abstract Article PDF–11M

Select item 88944633.

TRIM45 causes neuronal damage by aggravating microglia-mediated neuroinflammation upon cerebral ischemia and reperfusion injury

Qian Xia, Gaofeng Zhan, Meng Mao, Yin Zhao, Xing Li

Exp Mol Med. 2022 Feb; 54(2): 180–193. Published online 2022 Feb 25. doi: 10.1038/s12276-022-00734-y

PMCID:: PMC8894463

Abstract Article PDF–6.1M

Select item 88437074.

TAB2 deficiency induces dilated cardiomyopathy by promoting RIPK1-dependent apoptosis and necroptosis

Haifeng Yin, Xiaoyun Guo, Yi Chen, Yachang Zeng, Xiaoliang Mo, Siqi Hong, Hui He, Jing Li, Rachel Steinmetz, Qinghang Liu

J Clin Invest. 2022 Feb 15; 132(4): e152297. Published online 2022 Feb 15. doi: 10.1172/JCI152297

PMCID:: PMC8843707

Abstract Article PDF–2.7M

Select item 83220765.

The SUMOylation of TAB2 mediated by TRIM60 inhibits MAPK/NF-κB activation and the innate immune response

Zhiwen Gu, Xueying Chen, Wenyong Yang, Yu Qi, Hui Yu, Xiaomeng Wang, Yanqiu Gong, Qianqian Chen, Bo Zhong, Lunzhi Dai, Shiqian Qi, Zhiqiang Zhang, Huiyuan Zhang, Hongbo Hu

Cell Mol Immunol. 2021 Aug; 18(8): 1981–1994. Published online 2020 Nov 12. doi: 10.1038/s41423-020-00564-w

PMCID:: PMC8322076

Abstract Article PDF–1.7M

Select item 80988146.

The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis

Shalini Menon, Dennis Goldfarb, Chris T. Ho, Erica W. Cloer, Nicholas P. Boyer, Christopher Hardie, Andrew J. Bock, Emma C. Johnson, Joel Anil, M. Ben Major, Stephanie L. Gupton

Mol Biol Cell. 2021 Feb 15; 32(4): 314–330. doi: 10.1091/mbc.E20-10-0622

PMCID:: PMC8098814

Abstract Article PDF–7.7M

Select item 63334607.

ATG5 is required for B cell polarization and presentation of particulate antigens

Florent Arbogast, Johan Arnold, Philippe Hammann, Lauriane Kuhn, Johana Chicher, Diane Murera, Justine Weishaar, Sylviane Muller, Jean-Daniel Fauny, Frédéric Gros

Autophagy. 2019; 15(2): 280–294. Published online 2018 Sep 22. doi: 10.1080/15548627.2018.1516327

PMCID:: PMC6333460

Abstract Article PDF–2.7M

Select item 55588308.

Identification of a role for TRIM29 in the control of innate immunity in the respiratory tract

Junji Xing, Leiyun Weng, Bin Yuan, Zhuo Wang, Li Jia, Rui Jin, Hongbo Lu, Xian Chang Li, Yong-Jun Liu, Zhiqiang Zhang

Nat Immunol. Author manuscript; available in PMC 2017 Aug 16.

Published in final edited form as: Nat Immunol. 2016 Dec; 17(12): 1373–1380. Published online 2016 Oct 3. doi: 10.1038/ni.3580

Correction in:: Nat Immunol. 2016 Nov 16; 17(12): 1479.

PMCID:: PMC5558830

Abstract Article PDF–2.0M

Select item 47477689.

The LMO2 oncogene regulates DNA replication in hematopoietic cells

Marie-Claude Sincennes, Magali Humbert, Benoît Grondin, Véronique Lisi, Diogo F. T. Veiga, André Haman, Christophe Cazaux, Nazar Mashtalir, EL Bachir Affar, Alain Verreault, Trang Hoang

Proc Natl Acad Sci U S A. 2016 Feb 2; 113(5): 1393–1398. Published online 2016 Jan 13. doi: 10.1073/pnas.1515071113

PMCID:: PMC4747768

Abstract Article PDF–1.0M

Select item 439637710.

Glycogen synthase kinase 3β ubiquitination by TRAF6 regulates TLR3-mediated pro-inflammatory cytokine production

Ryeojin Ko, Jin Hee Park, Hyunil Ha, Yongwon Choi, Soo Young Lee

Nat Commun. 2015 Apr 1; 6: 6765. Published online 2015 Apr 1. doi: 10.1038/ncomms7765

PMCID:: PMC4396377

Abstract Article PDF–1.1M

Select item 398822911.

Activated Macrophage Survival Is Coordinated by TAK1 Binding Proteins

September R. Mihaly, Sho Morioka, Jun Ninomiya-Tsuji, Giichi Takaesu

PLoS One. 2014; 9(4): e94982. Published online 2014 Apr 15. doi: 10.1371/journal.pone.0094982

PMCID:: PMC3988229

Abstract Article PDF–2.9M

Select item 398114612.

USP10 inhibits genotoxic NF-κB activation by MCPIP1-facilitated deubiquitination of NEMO

Jixiao Niu, Yuling Shi, Jingyan Xue, Ruidong Miao, Shengping Huang, Tianyi Wang, Jiong Wu, Mingui Fu, Zhao-Hui Wu

EMBO J. 2013 Dec 11; 32(24): 3206–3219. Published online 2013 Nov 22. doi: 10.1038/emboj.2013.247

PMCID:: PMC3981146

Abstract Article PDF–1.3M

Select item 392696413.

TAK1 kinase switches cell fate from apoptosis to necrosis following TNF stimulation

Sho Morioka, Peter Broglie, Emily Omori, Yuka Ikeda, Giichi Takaesu, Kunihiro Matsumoto, Jun Ninomiya-Tsuji

J Cell Biol. 2014 Feb 17; 204(4): 607–623. doi: 10.1083/jcb.201305070

PMCID:: PMC3926964

Abstract Article PDF–3.6M

Select item 391219814.

TAK1 Binding Protein 2 Is Essential for Liver Protection from Stressors

Yuka Ikeda, Sho Morioka, Kunihiro Matsumoto, Jun Ninomiya-Tsuji

PLoS One. 2014; 9(2): e88037. Published online 2014 Feb 3. doi: 10.1371/journal.pone.0088037

PMCID:: PMC3912198

Abstract Article PDF–1.9M

Select item 363087715.

miR-155 Regulates Immune Modulatory Properties of Mesenchymal Stem Cells by Targeting TAK1-binding Protein 2

Chunliang Xu, Guangwen Ren, Gang Cao, Qing Chen, Peishun Shou, Chunxing Zheng, Liming Du, Xiaoyan Han, Menghui Jiang, Qian Yang, Liangyu Lin, Guan Wang, Pengfei Yu, Xin Zhang, Wei Cao, Gary Brewer, Ying Wang, Yufang Shi

J Biol Chem. 2013 Apr 19; 288(16): 11074–11079. Published online 2013 Feb 28. doi: 10.1074/jbc.M112.414862

PMCID:: PMC3630877

Abstract Article PDF–1.3M

Select item 351136916.

TAK1 (MAP3K7) Signaling Regulates Hematopoietic Stem Cells through TNF-Dependent and -Independent Mechanisms

Giichi Takaesu, Maiko Inagaki, Keiyo Takubo, Yuji Mishina, Paul R. Hess, Gregg A. Dean, Akihiko Yoshimura, Kunihiro Matsumoto, Toshio Suda, Jun Ninomiya-Tsuji

PLoS One. 2012; 7(11): e51073. Published online 2012 Nov 30. doi: 10.1371/journal.pone.0051073