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Select item 105938101.

Phase separation of BuGZ regulates gut regeneration and aging through interaction with m⁶A regulators

Qiaoqiao Zhang, Kai Deng, Mengyou Liu, Shengye Yang, Wei Xu, Tong Feng, Minwen Jie, Zhiming Liu, Xiao Sheng, Haiyang Chen, Hao Jiang

Nat Commun. 2023; 14: 6700. Published online 2023 Oct 23. doi: 10.1038/s41467-023-42474-1

PMCID:: PMC10593810

Abstract Article PDF–3.5M

Select item 101923612.

Indel driven rapid evolution of core nuclear pore protein gene promoters

David W. J. McQuarrie, Adam M. Read, Frannie H. S. Stephens, Alberto Civetta, Matthias Soller

Sci Rep. 2023; 13: 8035. Published online 2023 May 17. doi: 10.1038/s41598-023-34985-0

PMCID:: PMC10192361

Abstract Article PDF–2.2M

Select item 86644863.

Genome-wide phenotypic RNAi screen in the Drosophila wing: phenotypic description of functional classes

Ana López-Varea, Patricia Vega-Cuesta, Ana Ruiz-Gómez, Cristina M Ostalé, Cristina Molnar, Covadonga F Hevia, Mercedes Martín, Maria F Organista, Jesus de Celis, Joaquín Culí, Nuria Esteban, Jose F de Celis

G3 (Bethesda) 2021 Dec; 11(12): jkab349. Published online 2021 Oct 2. doi: 10.1093/g3journal/jkab349

PMCID:: PMC8664486

Abstract Article PDF–3.1M

Select item 85846704.

A behavioral screen for mediators of age-dependent TDP-43 neurodegeneration identifies SF2/SRSF1 among a group of potent suppressors in both neurons and glia

Jorge Azpurua, Enas Gad El-Karim, Marvel Tranquille, Josh Dubnau

PLoS Genet. 2021 Nov; 17(11): e1009882. Published online 2021 Nov 1. doi: 10.1371/journal.pgen.1009882

PMCID:: PMC8584670

Abstract Article PDF–1.4M

Select item 84460435.

Hecw controls oogenesis and neuronal homeostasis by promoting the liquid state of ribonucleoprotein particles

Valentina Fajner, Fabio Giavazzi, Simona Sala, Amanda Oldani, Emanuele Martini, Francesco Napoletano, Dario Parazzoli, Giuliana Cesare, Roberto Cerbino, Elena Maspero, Thomas Vaccari, Simona Polo

Nat Commun. 2021; 12: 5488. Published online 2021 Sep 16. doi: 10.1038/s41467-021-25809-8

PMCID:: PMC8446043

Abstract Article PDF–9.4M

Select item 82137276.

Hakai is required for stabilization of core components of the m⁶A mRNA methylation machinery

Praveen Bawankar, Tina Lence, Chiara Paolantoni, Irmgard U. Haussmann, Migle Kazlauskiene, Dominik Jacob, Jan B. Heidelberger, Florian M. Richter, Mohanakarthik P. Nallasivan, Violeta Morin, Nastasja Kreim, Petra Beli, Mark Helm, Martin Jinek, Matthias Soller, Jean-Yves Roignant

Nat Commun. 2021; 12: 3778. Published online 2021 Jun 18. doi: 10.1038/s41467-021-23892-5

PMCID:: PMC8213727

Abstract Article PDF–5.4M

Select item 82018547.

Genetic basis of variation in cocaine and methamphetamine consumption in outbred populations of Drosophila melanogaster

Brandon M. Baker, Mary Anna Carbone, Wen Huang, Robert R. H. Anholt, Trudy F. C. Mackay

Proc Natl Acad Sci U S A. 2021 Jun 8; 118(23): e2104131118. Published online 2021 May 31. doi: 10.1073/pnas.2104131118

PMCID:: PMC8201854

Abstract Article PDF–1.3M

Select item 80418518.

Role of Hakai in m⁶A modification pathway in Drosophila

Yanhua Wang, Lifeng Zhang, Hang Ren, Lijuan Ma, Jian Guo, Decai Mao, Zhongwen Lu, Lijun Lu, Dong Yan

Nat Commun. 2021; 12: 2159. Published online 2021 Apr 12. doi: 10.1038/s41467-021-22424-5

PMCID:: PMC8041851

Abstract Article PDF–3.1M

Select item 79584009.

mTORC1-chaperonin CCT signaling regulates m⁶A RNA methylation to suppress autophagy

Hong-Wen Tang, Jui-Hsia Weng, Wen Xing Lee, Yanhui Hu, Lei Gu, Sungyun Cho, Gina Lee, Richard Binari, Cathleen Li, Min En Cheng, Ah-Ram Kim, Jun Xu, Zhangfei Shen, Chiwei Xu, John M. Asara, John Blenis, Norbert Perrimon

Proc Natl Acad Sci U S A. 2021 Mar 9; 118(10): e2021945118. Published online 2021 Mar 1. doi: 10.1073/pnas.2021945118

PMCID:: PMC7958400

Abstract Article PDF–1.8M

Select item 696157810.

CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans

Ping Wei, Wen Xue, Yun Zhao, Guang Ning, Jiwu Wang

Genome Res. 2020 Jan; 30(1): 95–106. doi: 10.1101/gr.250811.119

PMCID:: PMC6961578

Abstract Article PDF–3.6M

Select item 693289011.

Identification of novel genes associated with longevity in Drosophila melanogaster - a computational approach

Bethany S. Hall, Yvonne A. Barnett, Jonathan J. Crofts, Nadia Chuzhanova

Aging (Albany NY) 2019 Dec 15; 11(23): 11244–11267. Published online 2019 Dec 3. doi: 10.18632/aging.102527

PMCID:: PMC6932890

Abstract Article PDF–1.2M

Select item 667935712.

Proximity labeling reveals novel interactomes in live Drosophila tissue

Katelynn M. Mannix, Rebecca M. Starble, Ronit S. Kaufman, Lynn Cooley

Development. 2019 Jul 15; 146(14): dev176644. Published online 2019 Jul 18. doi: 10.1242/dev.176644

PMCID:: PMC6679357

Abstract Article

Select item 650653913.

Tissue-specific (ts)CRISPR as an efficient strategy for in vivo screening in Drosophila

Hagar Meltzer, Efrat Marom, Idan Alyagor, Oded Mayseless, Victoria Berkun, Netta Segal-Gilboa, Tamar Unger, David Luginbuhl, Oren Schuldiner

Nat Commun. 2019; 10: 2113. Published online 2019 May 8. doi: 10.1038/s41467-019-10140-0

PMCID:: PMC6506539

Abstract Article PDF–6.5M

Select item 615500014.

Discovering human diabetes-risk gene function with genetics and physiological assays

Heshan Peiris, Sangbin Park, Shreya Louis, Xueying Gu, Jonathan Y. Lam, Olof Asplund, Gregory C. Ippolito, Rita Bottino, Leif Groop, Haley Tucker, Seung K. Kim

Nat Commun. 2018; 9: 3855. Published online 2018 Sep 21. doi: 10.1038/s41467-018-06249-3

PMCID:: PMC6155000

Abstract Article PDF–2.2M

Select item 590890715.

The Emerging Field of Epitranscriptomics in Neurodevelopmental and Neuronal Disorders

Margarita T. Angelova, Dilyana G. Dimitrova, Nadja Dinges, Tina Lence, Lina Worpenberg, Clément Carré, Jean-Yves Roignant

Front Bioeng Biotechnol. 2018; 6: 46. Published online 2018 Apr 13. doi: 10.3389/fbioe.2018.00046

PMCID:: PMC5908907

Abstract Article PDF–1.2M

Select item 590071416.

Zc3h13/Flacc is required for adenosine methylation by bridging the mRNA-binding factor Rbm15/Spenito to the m⁶A machinery component Wtap/Fl(2)d

Philip Knuckles, Tina Lence, Irmgard U. Haussmann, Dominik Jacob, Nastasja Kreim, Sarah H. Carl, Irene Masiello, Tina Hares, Rodrigo Villaseñor, Daniel Hess, Miguel A. Andrade-Navarro, Marco Biggiogera, Mark Helm, Matthias Soller, Marc Bühler, Jean-Yves Roignant

Genes Dev. 2018 Mar 1; 32(5-6): 415–429. doi: 10.1101/gad.309146.117