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Items: 1 to 20 of 49

1.
Genetic and molecular analysis of the synaptotagmin family
B. Adolfsen, J.T. Littleton
Cell Mol Life Sci. 2001 Mar; 58(3): 393–402. doi: 10.1007/PL00000865
PMCID:
PMC11337341
ArticlePDF–180K
2.
The effects of methylphenidate and atomoxetine on Drosophila brain at single-cell resolution and potential drug repurposing for ADHD treatment
Susu Qu, Xiangyu Zhou, Zhicheng Wang, Yi Wei, Han Zhou, Xinshuang Zhang, Qingjie Zhu, Yanmin Wang, Quanjun Yang, Likun Jiang, Yuan Ma, Yuan Gao, Lei Kong, Li Zhang
Mol Psychiatry. 2024; 29(1): 165–185. Published online 2023 Nov 13. doi: 10.1038/s41380-023-02314-6
PMCID:
PMC11078728
ArticlePDF–4.8M
3.
Fourth Chromosome Resource Project: a comprehensive resource for genetic analysis in Drosophila that includes humanized stocks
Michael J Stinchfield, Brandon P Weasner, Bonnie M Weasner, David Zhitomersky, Justin P Kumar, Michael B O’Connor, Stuart J Newfeld
Genetics. 2024 Feb; 226(2): iyad201. Published online 2023 Nov 20. doi: 10.1093/genetics/iyad201
PMCID:
PMC10847715
ArticlePDF–1.2M
4.
The disease-associated proteins Drosophila Nab2 and Ataxin-2 interact with shared RNAs and coregulate neuronal morphology
J Christopher Rounds, Edwin B Corgiat, Changtian Ye, Joseph A Behnke, Seth M Kelly, Anita H Corbett, Kenneth H Moberg
Genetics. 2022 Jan; 220(1): iyab175. Published online 2022 Jan 3. doi: 10.1093/genetics/iyab175
PMCID:
PMC8733473
ArticlePDF–2.4M
5.
The decoy SNARE Tomosyn sets tonic versus phasic release properties and is required for homeostatic synaptic plasticity
Chad W Sauvola, Yulia Akbergenova, Karen L Cunningham, Nicole A Aponte-Santiago, J Troy Littleton
eLife. 2021; 10: e72841. Published online 2021 Oct 29. doi: 10.7554/eLife.72841
PMCID:
PMC8612732
ArticlePDF–5.9M
6.
Transcriptional Correlates of Chronic Alcohol Neuroadaptation in Drosophila Larvae
Amanda Anqueira-González, Jenny P. Acevedo-Gonzalez, Airined Montes-Mercado, Claudia Irizarry-Hernández, Nicolás L. Fuenzalida-Uribe, Alfredo Ghezzi
Front Behav Neurosci. 2021; 15: 768694. Published online 2021 Nov 4. doi: 10.3389/fnbeh.2021.768694
PMCID:
PMC8599819
ArticlePDF–1.0M
7.
Function of Drosophila Synaptotagmins in membrane trafficking at synapses
Mónica C. Quiñones-Frías, J. Troy Littleton
Cell Mol Life Sci. 2021 May; 78(9): 4335–4364. Published online 2021 Feb 22. doi: 10.1007/s00018-021-03788-9
PMCID:
PMC8164606
ArticlePDF–2.7M
8.
Downregulation of glial genes involved in synaptic function mitigates Huntington's disease pathogenesis
Tarik Seref Onur, Andrew Laitman, He Zhao, Ryan Keyho, Hyemin Kim, Jennifer Wang, Megan Mair, Huilan Wang, Lifang Li, Alma Perez, Maria de Haro, Ying-Wooi Wan, Genevera Allen, Boxun Lu, Ismael Al-Ramahi, Zhandong Liu, Juan Botas
eLife. 2021; 10: e64564. Published online 2021 Apr 19. doi: 10.7554/eLife.64564
PMCID:
PMC8149125
ArticlePDF–3.5M
9.
Comprehensive Identification and Alternative Splicing of Microexons in Drosophila
Ting-Lin Pang, Zhan Ding, Shao-Bo Liang, Liang Li, Bei Zhang, Yu Zhang, Yu-Jie Fan, Yong-Zhen Xu
Front Genet. 2021; 12: 642602. Published online 2021 Mar 30. doi: 10.3389/fgene.2021.642602
PMCID:
PMC8042270
ArticlePDF–3.6M
10.
Synaptotagmin 7 switches short-term synaptic plasticity from depression to facilitation by suppressing synaptic transmission
Takaaki Fujii, Akira Sakurai, J. Troy Littleton, Motojiro Yoshihara
Sci Rep. 2021; 11: 4059. Published online 2021 Feb 18. doi: 10.1038/s41598-021-83397-5
PMCID:
PMC7892890
ArticlePDF–1.3M
11.
Transcriptomic and proteomic profiling of glial versus neuronal Dube3a overexpression reveals common molecular changes in gliopathic epilepsies
Kevin A. Hope, Daniel Johnson, P. Winston Miller, Daniel Lopez-Ferrer, David Kakhniashvili, Lawrence T. Reiter
Neurobiol Dis. Author manuscript; available in PMC 2021 Jul 1.
Published in final edited form as: Neurobiol Dis. 2020 Jul; 141: 104879. Published online 2020 Apr 25. doi: 10.1016/j.nbd.2020.104879
PMCID:
PMC7311295
ArticlePDF–1.3M
12.
Drosophila Synaptotagmin 7 negatively regulates synaptic vesicle release and replenishment in a dosage-dependent manner
Zhuo Guan, Monica C Quiñones-Frías, Yulia Akbergenova, J Troy Littleton
eLife. 2020; 9: e55443. Published online 2020 Apr 28. doi: 10.7554/eLife.55443
PMCID:
PMC7224696
ArticlePDF–5.6M
13.
CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans
Ping Wei, Wen Xue, Yun Zhao, Guang Ning, Jiwu Wang
Genome Res. 2020 Jan; 30(1): 95–106. doi: 10.1101/gr.250811.119
PMCID:
PMC6961578
ArticlePDF–3.6M
14.
Molecular and genetic organization of bands and interbands in the dot chromosome of Drosophila melanogaster
Darya S. Sidorenko, Ivan A. Sidorenko, Tatyana Yu. Zykova, Fedor P. Goncharov, Jan Larsson, Igor F. Zhimulev
Chromosoma. 2019; 128(2): 97–117. Published online 2019 Apr 30. doi: 10.1007/s00412-019-00703-x
PMCID:
PMC6536484
ArticlePDF–8.1M
15.
Complexin cooperates with Bruchpilot to tether synaptic vesicles to the active zone cytomatrix
Nicole Scholz, Nadine Ehmann, Divya Sachidanandan, Cordelia Imig, Benjamin H. Cooper, Olaf Jahn, Kerstin Reim, Nils Brose, Jutta Meyer, Marius Lamberty, Steffen Altrichter, Anne Bormann, Stefan Hallermann, Martin Pauli, Manfred Heckmann, Christian Stigloher, Tobias Langenhan, Robert J. Kittel
J Cell Biol. 2019 Mar 4; 218(3): 1011–1026. doi: 10.1083/jcb.201806155
PMCID:
PMC6400551
ArticlePDF–2.9M
16.
Bub1 Facilitates Virus Entry through Endocytosis in a Model of Drosophila Pathogenesis
Shuo Yang, Junjing Yu, Zhiqin Fan, Si-tang Gong, Hong Tang, Lei Pan
J Virol. 2018 Sep 15; 92(18): e00254-18. Prepublished online 2018 Jul 5. Published online 2018 Aug 29. doi: 10.1128/JVI.00254-18
PMCID:
PMC6146689
ArticlePDF–405K
17.
Landscape and evolution of tissue-specific alternative polyadenylation across Drosophila species
Piero Sanfilippo, Jiayu Wen, Eric C. Lai
Genome Biol. 2017; 18: 229. Published online 2017 Nov 30. doi: 10.1186/s13059-017-1358-0
PMCID:
PMC5707805
ArticlePDF–3.2M
18.
Transcription elongation rate has a tissue-specific impact on alternative cleavage and polyadenylation in Drosophila melanogaster
Xiaochuan Liu, Jaime Freitas, Dinghai Zheng, Marta S. Oliveira, Mainul Hoque, Torcato Martins, Telmo Henriques, Bin Tian, Alexandra Moreira
RNA. 2017 Dec; 23(12): 1807–1816. doi: 10.1261/rna.062661.117
PMCID:
PMC5689002
ArticlePDF–4.0M
19.
The Insect Prothoracic Gland as a Model for Steroid Hormone Biosynthesis and Regulation
Qiuxiang Ou, Jie Zeng, Naoki Yamanaka, Christina Brakken-Thal, Michael B. O’Connor, Kirst King-Jones
Cell Rep. Author manuscript; available in PMC 2017 Mar 2.
Published in final edited form as: Cell Rep. 2016 Jun 28; 16(1): 247–262. Published online 2016 Jun 16. doi: 10.1016/j.celrep.2016.05.053
PMCID:
PMC5333552
ArticlePDF–2.7M
20.
Vesicle-Mediated Steroid Hormone Secretion in Drosophila melanogaster
Naoki Yamanaka, Guillermo Marqués, Michael B. O’Connor
Cell. Author manuscript; available in PMC 2016 Nov 5.
Published in final edited form as: Cell. 2015 Nov 5; 163(4): 907–919. doi: 10.1016/j.cell.2015.10.022
PMCID:
PMC4636736
ArticlePDF–2.3M

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