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Select item 99815351.

A large-scale RNAi screen reveals that mitochondrial function is important for meiotic chromosome organization in oocytes

Karen Jule Nieken, Kathryn O’Brien, Alexander McDonnell, Liudmila Zhaunova, Hiroyuki Ohkura

Chromosoma. 2023; 132(1): 1–18. Published online 2023 Jan 17. doi: 10.1007/s00412-023-00784-9

PMCID:: PMC9981535

Abstract Article PDF–3.4M

Select item 92396802.

An expanded toolkit for Drosophila gene tagging using synthesized homology donor constructs for CRISPR-mediated homologous recombination

Oguz Kanca, Jonathan Zirin, Yanhui Hu, Burak Tepe, Debdeep Dutta, Wen-Wen Lin, Liwen Ma, Ming Ge, Zhongyuan Zuo, Lu-Ping Liu, Robert W Levis, Norbert Perrimon, Hugo J Bellen

eLife. 2022; 11: e76077. Published online 2022 Jun 20. doi: 10.7554/eLife.76077

PMCID:: PMC9239680

Abstract Article PDF–1.2M

Select item 86644863.

Genome-wide phenotypic RNAi screen in the Drosophila wing: phenotypic description of functional classes

Ana López-Varea, Patricia Vega-Cuesta, Ana Ruiz-Gómez, Cristina M Ostalé, Cristina Molnar, Covadonga F Hevia, Mercedes Martín, Maria F Organista, Jesus de Celis, Joaquín Culí, Nuria Esteban, Jose F de Celis

G3 (Bethesda) 2021 Dec; 11(12): jkab349. Published online 2021 Oct 2. doi: 10.1093/g3journal/jkab349

PMCID:: PMC8664486

Abstract Article PDF–3.1M

Select item 86644554.

Functional requirements of protein kinases and phosphatases in the development of the Drosophila melanogaster wing

Cristina M Ostalé, Nuria Esteban, Ana López-Varea, Jose F de Celis

G3 (Bethesda) 2021 Dec; 11(12): jkab348. Published online 2021 Oct 2. doi: 10.1093/g3journal/jkab348

PMCID:: PMC8664455

Abstract Article PDF–2.9M

Select item 80229465.

An RNAi screen of the kinome in epithelial follicle cells of the Drosophila melanogaster ovary reveals genes required for proper germline death and clearance

Diane P V Lebo, Alice Chirn, Jeffrey D Taylor, Andre Levan, Valentina Doerre Torres, Emily Agreda, Sandy B Serizier, Allison K Lord, Victoria K Jenkins, Kimberly McCall

G3 (Bethesda) 2021 Feb; 11(2): jkaa066. Published online 2021 Mar 6. doi: 10.1093/g3journal/jkaa066

PMCID:: PMC8022946

Abstract Article PDF–1.3M

Select item 69615786.

CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans

Ping Wei, Wen Xue, Yun Zhao, Guang Ning, Jiwu Wang

Genome Res. 2020 Jan; 30(1): 95–106. doi: 10.1101/gr.250811.119

PMCID:: PMC6961578

Abstract Article PDF–3.6M

Select item 65482277.

Cross-species genetic screens to identify kinase targets for APP reduction in Alzheimer's disease

Claudia H Huichalaf, Ismael Al-Ramahi, Kyung-Won Park, Stacy D Grunke, Nan Lu, Maria de Haro, Karla El-Zein, Tatiana Gallego-Flores, Alma M Perez, Sung Yun Jung, Juan Botas, Huda Y Zoghbi, Joanna L Jankowsky

Hum Mol Genet. 2019 Jun 15; 28(12): 2014–2029. Published online 2019 Feb 12. doi: 10.1093/hmg/ddz034

PMCID:: PMC6548227

Abstract Article PDF–24M

Select item 59313698.

A Whole Animal Platform to Advance A Clinical Kinase Inhibitor Into New Disease Space

Masahiro Sonoshita, Alex P. Scopton, Peter M-U. Ung, Matthew A. Murray, Lisa Silber, Andres Y. Maldonado, Alexander Real, Avner Schlessinger, Ross L. Cagan, Arvin C. Dar

Nat Chem Biol. Author manuscript; available in PMC 2018 Jul 22.

Published in final edited form as: Nat Chem Biol. 2018 Mar; 14(3): 291–298. Published online 2018 Jan 22. doi: 10.1038/nchembio.2556

PMCID:: PMC5931369

Abstract Article PDF–2.9M

Select item 57078059.

Landscape and evolution of tissue-specific alternative polyadenylation across Drosophila species

Piero Sanfilippo, Jiayu Wen, Eric C. Lai

Genome Biol. 2017; 18: 229. Published online 2017 Nov 30. doi: 10.1186/s13059-017-1358-0

PMCID:: PMC5707805

Abstract Article PDF–3.2M

Select item 568900210.

Transcription elongation rate has a tissue-specific impact on alternative cleavage and polyadenylation in Drosophila melanogaster

Xiaochuan Liu, Jaime Freitas, Dinghai Zheng, Marta S. Oliveira, Mainul Hoque, Torcato Martins, Telmo Henriques, Bin Tian, Alexandra Moreira

RNA. 2017 Dec; 23(12): 1807–1816. doi: 10.1261/rna.062661.117

PMCID:: PMC5689002

Abstract Article PDF–4.0M

Select item 520424611.

Developmental inhibition of miR-iab8-3p disrupts mushroom body neuron structure and adult learning ability

Germain U. Busto, Tugba Guven-Ozkan, Molee Chakraborty, Ronald L. Davis

Dev Biol. Author manuscript; available in PMC 2017 Jan 2.

Published in final edited form as: Dev Biol. 2016 Nov 15; 419(2): 237–249. Published online 2016 Sep 12. doi: 10.1016/j.ydbio.2016.09.010

PMCID:: PMC5204246

Abstract Article PDF–1.7M

Select item 488965812.

mRNA-Associated Processes and Their Influence on Exon-Intron Structure in Drosophila melanogaster

Gildas Lepennetier, Francesco Catania

G3 (Bethesda) 2016 Jun; 6(6): 1617–1626. Published online 2016 Mar 28. doi: 10.1534/g3.116.029231

PMCID:: PMC4889658

Abstract Article PDF–1.5M

Select item 476647613.

Cdk12 Is A Gene-Selective RNA Polymerase II Kinase That Regulates a Subset of the Transcriptome, Including Nrf2 Target Genes

Xuan Li, Nirmalya Chatterjee, Kerstin Spirohn, Michael Boutros, Dirk Bohmann

Sci Rep. 2016; 6: 21455. Published online 2016 Feb 25. doi: 10.1038/srep21455

PMCID:: PMC4766476

Abstract Article PDF–1.5M

Select item 473800514.

Proteome-wide dataset supporting the study of ancient metazoan macromolecular complexes

Sadhna Phanse, Cuihong Wan, Blake Borgeson, Fan Tu, Kevin Drew, Greg Clark, Xuejian Xiong, Olga Kagan, Julian Kwan, Alexandr Bezginov, Kyle Chessman, Swati Pal, Graham Cromar, Ophelia Papoulas, Zuyao Ni, Daniel R. Boutz, Snejana Stoilova, Pierre C. Havugimana, Xinghua Guo, Ramy H. Malty, Mihail Sarov, Jack Greenblatt, Mohan Babu, W. Brent Derry, Elisabeth R. Tillier, John B. Wallingford, John Parkinson, Edward M. Marcotte, Andrew Emili

Data Brief. 2016 Mar; 6: 715–721. Published online 2015 Dec 12. doi: 10.1016/j.dib.2015.11.062

PMCID:: PMC4738005

Abstract Article PDF–205K

Select item 473615915.

The novel tumour suppressor Madm regulates stem cell competition in the Drosophila testis

Shree Ram Singh, Ying Liu, Jiangsha Zhao, Xiankun Zeng, Steven X. Hou

Nat Commun. 2016; 7: 10473. Published online 2016 Jan 21. doi: 10.1038/ncomms10473

PMCID:: PMC4736159

Abstract Article PDF–3.7M

Select item 465324316.

Bunched and Madm Function Downstream of Tuberous Sclerosis Complex to Regulate the Growth of Intestinal Stem Cells in Drosophila

Yingchao Nie, Qi Li, Alla Amcheslavsky, Juan Carlos Duhart, Alexey Veraksa, Hugo Stocker, Laurel A. Raftery, Y. Tony Ip

Stem Cell Rev. 2015; 11(6): 813–825. Published online 2015 Sep 2. doi: 10.1007/s12015-015-9617-5

PMCID:: PMC4653243

Abstract Article PDF–1.7M

Select item 461527917.

Drosophila Symplekin localizes dynamically to the histone locus body and tricellular junctions

Deirdre C Tatomer, Lindsay F Rizzardi, Kaitlin P Curry, Alison M Witkowski, William F Marzluff, Robert J Duronio

Nucleus. 2014; 5(6): 613–625. Published online 2014 Dec 10. doi: 10.4161/19491034.2014.990860

PMCID:: PMC4615279

Abstract Article PDF–1.1M

Select item 457069718.

Putative synaptic genes defined from a Drosophila whole body developmental transcriptome by a machine learning approach

Flavio Pazos Obregón, Cecilia Papalardo, Sebastián Castro, Gustavo Guerberoff, Rafael Cantera

BMC Genomics. 2015; 16(1): 694. Published online 2015 Sep 15. doi: 10.1186/s12864-015-1888-3

PMCID:: PMC4570697

Abstract Article PDF–2.0M

Select item 452833019.

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders

Madeline A. Crosby, L. Sian Gramates, Gilberto dos Santos, Beverley B. Matthews, Susan E. St. Pierre, Pinglei Zhou, Andrew J. Schroeder, Kathleen Falls, David B. Emmert, Susan M. Russo, William M. Gelbart, the FlyBase Consortium

G3 (Bethesda) 2015 Aug; 5(8): 1737–1749. Published online 2015 Jun 24. doi: 10.1534/g3.115.018937

PMCID:: PMC4528330

Abstract Article PDF–2.2M

Select item 452832920.

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data

Beverley B. Matthews, Gilberto dos Santos, Madeline A. Crosby, David B. Emmert, Susan E. St. Pierre, L. Sian Gramates, Pinglei Zhou, Andrew J. Schroeder, Kathleen Falls, Victor Strelets, Susan M. Russo, William M. Gelbart, the FlyBase Consortium

G3 (Bethesda) 2015 Aug; 5(8): 1721–1736. Published online 2015 Jun 24. doi: 10.1534/g3.115.018929

PMCID:: PMC4528329

Abstract Article PDF–4.9M

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