PMC Links for GEO Profiles (Select 22375348) - PMC

Select item 91226081.

SCF ubiquitin E3 ligase regulates DNA double-strand breaks in early meiotic recombination

Yongjuan Guan, Huijuan Lin, N Adrian Leu, Gordon Ruthel, Serge Y Fuchs, Luca Busino, Mengcheng Luo, P Jeremy Wang

Nucleic Acids Res. 2022 May 20; 50(9): 5129–5144. Published online 2022 Apr 30. doi: 10.1093/nar/gkac304

PMCID:: PMC9122608

Abstract Article PDF–13M

Select item 77080772.

The ssDNA-binding protein MEIOB acts as a dosage-sensitive regulator of meiotic recombination

Rui Guo, Yang Xu, N Adrian Leu, Lei Zhang, Serge Y Fuchs, Lan Ye, P Jeremy Wang

Nucleic Acids Res. 2020 Dec 2; 48(21): 12219–12233. Published online 2020 Nov 9. doi: 10.1093/nar/gkaa1016

PMCID:: PMC7708077

Abstract Article PDF–6.7M

Select item 75236923.

A cell-based high-content screen identifies isocotoin as a small molecule inhibitor of the meiosis-specific MEIOB–SPATA22 complex

Yang Xu, Rong Liu, N Adrian Leu, Lei Zhang, Ilsiya Ibragmova, David C Schultz, P Jeremy Wang

Biol Reprod. 2020 Aug; 103(2): 333–342. Published online 2020 Apr 25. doi: 10.1093/biolre/ioaa062

PMCID:: PMC7523692

Abstract Article PDF–4.9M

Select item 71888234.

The BRCA2-MEILB2-BRME1 complex governs meiotic recombination and impairs the mitotic BRCA2-RAD51 function in cancer cells

Jingjing Zhang, Manickam Gurusaran, Yasuhiro Fujiwara, Kexin Zhang, Meriem Echbarthi, Egor Vorontsov, Rui Guo, Devon F. Pendlebury, Intekhab Alam, Gabriel Livera, Martini Emmanuelle, P. Jeremy Wang, Jayakrishnan Nandakumar, Owen R. Davies, Hiroki Shibuya

Nat Commun. 2020; 11: 2055. Published online 2020 Apr 28. doi: 10.1038/s41467-020-15954-x

PMCID:: PMC7188823

Abstract Article PDF–4.0M

Select item 63551045.

Meiosis-specific proteins MEIOB and SPATA22 cooperatively associate with the single-stranded DNA-binding replication protein A complex and DNA double-strand breaks

Yang Xu, Roger A. Greenberg, Ernst Schonbrunn, P. Jeremy Wang

Biol Reprod. 2017 May; 96(5): 1096–1104. Published online 2017 Apr 27. doi: 10.1093/biolre/iox040

PMCID:: PMC6355104

Abstract Article PDF–1.6M

Select item 57850336.

MORC2B is essential for meiotic progression and fertility

Baolu Shi, Jiangyang Xue, Jian Zhou, Seth D. Kasowitz, Yuanwei Zhang, Guanxiang Liang, Yongjuan Guan, Qinghua Shi, Mingxi Liu, Jiahao Sha, Xiaoyan Huang, P. Jeremy Wang

PLoS Genet. 2018 Jan; 14(1): e1007175. Published online 2018 Jan 12. doi: 10.1371/journal.pgen.1007175

PMCID:: PMC5785033

Abstract Article PDF–19M

Select item 47299027.

Implementation of meiosis prophase I programme requires a conserved retinoid-independent stabilizer of meiotic transcripts

Emilie Abby, Sophie Tourpin, Jonathan Ribeiro, Katrin Daniel, Sébastien Messiaen, Delphine Moison, Justine Guerquin, Jean-Charles Gaillard, Jean Armengaud, Francina Langa, Attila Toth, Emmanuelle Martini, Gabriel Livera

Nat Commun. 2016; 7: 10324. Published online 2016 Jan 8. doi: 10.1038/ncomms10324

PMCID:: PMC4729902

Abstract Article PDF–4.0M

Select item 38918318.

MEIOB exhibits single-stranded DNA-binding and exonuclease activities and is essential for meiotic recombination

Mengcheng Luo, Fang Yang, N. Adrian Leu, Jessica Landaiche, Mary Ann Handel, Ricardo Benavente, Sophie La Salle, P. Jeremy Wang

Nat Commun. Author manuscript; available in PMC 2014 May 18.

Published in final edited form as: Nat Commun. 2013; 4: 2788. doi: 10.1038/ncomms3788

PMCID:: PMC3891831

Abstract Article PDF–4.4M

Select item 37780099.

MEIOB Targets Single-Strand DNA and Is Necessary for Meiotic Recombination

Benoit Souquet, Emilie Abby, Roxane Hervé, Friederike Finsterbusch, Sophie Tourpin, Ronan Le Bouffant, Clotilde Duquenne, Sébastien Messiaen, Emmanuelle Martini, Jacqueline Bernardino-Sgherri, Attila Toth, René Habert, Gabriel Livera

PLoS Genet. 2013 Sep; 9(9): e1003784. Published online 2013 Sep 19. doi: 10.1371/journal.pgen.1003784

PMCID:: PMC3778009

Abstract Article PDF–14M

Select item 357241010.

A conditional knockout resource for the genome–wide study of mouse gene function

William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley

Nature. Author manuscript; available in PMC 2013 Feb 14.

Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163

PMCID:: PMC3572410

Abstract Article PDF–1.1M

Select item 317805911.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 31099212.

RIKEN Integrated Sequence Analysis (RISA) System—384-Format Sequencing Pipeline with 384 Multicapillary Sequencer

Kazuhiro Shibata, Masayoshi Itoh, Katsunori Aizawa, Sumiharu Nagaoka, Nobuya Sasaki, Piero Carninci, Hideaki Konno, Junichi Akiyama, Katsuo Nishi, Tokuji Kitsunai, Hideo Tashiro, Mari Itoh, Noriko Sumi, Yoshiyuki Ishii, Shin Nakamura, Makoto Hazama, Tsutomu Nishine, Akira Harada, Rintaro Yamamoto, Hiroyuki Matsumoto, Sumito Sakaguchi, Takashi Ikegami, Katsuya Kashiwagi, Syuji Fujiwake, Kouji Inoue, Yoshiyuki Togawa, Masaki Izawa, Eiji Ohara, Masanori Watahiki, Yuko Yoneda, Tomokazu Ishikawa, Kaori Ozawa, Takumi Tanaka, Shuji Matsuura, Jun Kawai, Yasushi Okazaki, Masami Muramatsu, Yorinao Inoue, Akira Kira, Yoshihide Hayashizaki

Genome Res. 2000 Nov; 10(11): 1757–1771. doi: 10.1101/gr.152600

PMCID:: PMC310992

Abstract Article PDF–3.4M

Select item 31098013.

Normalization and Subtraction of Cap-Trapper-Selected cDNAs to Prepare Full-Length cDNA Libraries for Rapid Discovery of New Genes

Piero Carninci, Yuko Shibata, Norihito Hayatsu, Yuichi Sugahara, Kazuhiro Shibata, Masayoshi Itoh, Hideaki Konno, Yasushi Okazaki, Masami Muramatsu, Yoshihide Hayashizaki

Genome Res. 2000 Oct; 10(10): 1617–1630. doi: 10.1101/gr.145100

PMCID:: PMC310980

Abstract Article PDF–1.4M

Select item 28355414.

Wnk1 kinase deficiency lowers blood pressure in mice: A gene-trap screen to identify potential targets for therapeutic intervention

Brian P. Zambrowicz, Alejandro Abuin, Ramiro Ramirez-Solis, Lizabeth J. Richter, James Piggott, Hector BeltrandelRio, Eric C. Buxton, Joel Edwards, Rick A. Finch, Carl J. Friddle, Anupma Gupta, Gwenn Hansen, Yi Hu, Wenhu Huang, Crystal Jaing, Billie Wayne Key, Jr., Peter Kipp, Buckley Kohlhauff, Zhi-Qing Ma, Diane Markesich, Robert Payne, David G. Potter, Ny Qian, Joseph Shaw, Jeff Schrick, Zheng-Zheng Shi, Mary Jean Sparks, Isaac Van Sligtenhorst, Peter Vogel, Wade Walke, Nianhua Xu, Qichao Zhu, Christophe Person, Arthur T. Sands

Proc Natl Acad Sci U S A. 2003 Nov 25; 100(24): 14109–14114. Published online 2003 Nov 10. doi: 10.1073/pnas.2336103100

Correction in:: Proc Natl Acad Sci U S A. 2004 Mar 23; 101(12): 4332.

PMCID:: PMC283554

Abstract Article PDF–481K

Select item 13924115.

Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences

Mammalian Gene Collection (MGC) Program Team

Proc Natl Acad Sci U S A. 2002 Dec 24; 99(26): 16899–16903. Published online 2002 Dec 11. doi: 10.1073/pnas.242603899

PMCID:: PMC139241

Abstract Article PDF–118K

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