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Items: 1 to 20 of 74

1.
CD3ζ ITAMs enable ligand discrimination and antagonism by inhibiting TCR signaling in response to low-affinity peptides
Guillaume Gaud, Sooraj Achar, François X. P. Bourassa, John Davies, Teri Hatzihristidis, Seeyoung Choi, Taisuke Kondo, Selamawit Gossa, Jan Lee, Paul Juneau, Naomi Taylor, Christian S. Hinrichs, Dorian B. McGavern, Paul François, Grégoire Altan-Bonnet, Paul E. Love
Nat Immunol. Author manuscript; available in PMC 2024 Oct 16.
Published in final edited form as: Nat Immunol. 2023 Dec; 24(12): 2121–2134. Published online 2023 Nov 9. doi: 10.1038/s41590-023-01663-2
Correction in:
Nat Immunol. 2023 Dec 6
PMCID:
PMC11482260
AbstractArticlePDF–6.1M
2.
CD3ζ-Mediated Signaling Protects Retinal Ganglion Cells in Glutamate Excitotoxicity of the Retina
Rui Du, Ping Wang, Ning Tian
Cells. 2024 Jun; 13(12): 1006. Published online 2024 Jun 8. doi: 10.3390/cells13121006
PMCID:
PMC11201742
AbstractArticlePDF–25M
3.
A set point in the selection of the αβTCR T cell repertoire imposed by pre-TCR signaling strength
Elena R. Bovolenta, Eva M. García-Cuesta, Lydia Horndler, Julia Ponomarenko, Wolfgang W. Schamel, Mario Mellado, Mario Castro, David Abia, Hisse M. van Santen
Proc Natl Acad Sci U S A. 2022 May 31; 119(22): e2201907119. Published online 2022 May 26. doi: 10.1073/pnas.2201907119
PMCID:
PMC9295770
AbstractArticlePDF–1.6M
4.
Reduction of Cell Surface T-Cell Receptor by Non-Mitogenic CD3 Antibody to Mitigate Murine Lupus
Masashi Morita, Masayuki Mizui, Satoshi Masuyama, George C. Tsokos, Yoshitaka Isaka
Front Immunol. 2022; 13: 855812. Published online 2022 Mar 28. doi: 10.3389/fimmu.2022.855812
PMCID:
PMC8995471
AbstractArticlePDF–4.6M
5.
The CD3ζ adaptor structure determines functional differences between human and mouse CD16 Fc receptor signaling
Oscar A. Aguilar, Lam-Kiu Fong, Kenichi Ishiyama, William F. DeGrado, Lewis L. Lanier
J Exp Med. 2022 May 2; 219(5): e20220022. Published online 2022 Mar 23. doi: 10.1084/jem.20220022
PMCID:
PMC8953085
AbstractArticlePDF–6.1M
6.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
7.
Impaired Spatial Memory in Mice Lacking CD3ζ Is Associated with Altered NMDA and AMPA Receptors Signaling Independent of T-Cell Deficiency
Antoine Louveau, Julie Angibaud, Fabienne Haspot, Maria Cecilia Opazo, Reynald Thinard, Virginie Thepenier, Stéphane J. Baudouin, Laurent Lescaudron, Philippe Hulin, Claudia A. Riedel, Hélène Boudin
J Neurosci. 2013 Nov 20; 33(47): 18672–18685. doi: 10.1523/JNEUROSCI.3028-13.2013
PMCID:
PMC6618807
AbstractArticlePDF–2.8M
8.
Interleukin-17 producing γδ T cells originate from SOX13+ progenitors that are independent of γδTCR signaling
Nicholas A Spidale, Katelyn Sylvia, Kavitha Narayan, Bing Miu, Michela Frascoli, Heather J Melichar, Wu Zhihao, Jan Kisielow, Amy Palin, Thomas Serwold, Paul Love, Michihiro Kobayashi, Momoko Yoshimoto, Nitya Jain, Joonsoo Kang
Immunity. Author manuscript; available in PMC 2019 Nov 20.
Published in final edited form as: Immunity. 2018 Nov 20; 49(5): 857–872.e5. Published online 2018 Nov 6. doi: 10.1016/j.immuni.2018.09.010
PMCID:
PMC6249057
AbstractArticlePDF–1.5M
9.
SOX4 controls invariant NKT cell differentiation by tuning TCR signaling
Nidhi Malhotra, Yilin Qi, Nicholas A. Spidale, Michela Frascoli, Bing Miu, Okhyun Cho, Katelyn Sylvia, Joonsoo Kang
J Exp Med. 2018 Nov 5; 215(11): 2887–2900. doi: 10.1084/jem.20172021
PMCID:
PMC6219734
AbstractArticlePDF–2.7M
10.
Interferon-α Up-Regulates the Expression of PD-L1 Molecules on Immune Cells Through STAT3 and p38 Signaling
Alexandr V. Bazhin, Katharina von Ahn, Jasmin Fritz, Jens Werner, Svetlana Karakhanova
Front Immunol. 2018; 9: 2129. Published online 2018 Sep 27. doi: 10.3389/fimmu.2018.02129
PMCID:
PMC6190899
AbstractArticlePDF–1.8M
11.
NK cell receptor NKG2D sets activation threshold for the NCR1 receptor early in NK cell development
Vedrana Jelenčić, Marko Šestan, Inga Kavazović, Maja Lenartić, Sonja Marinović, Tim D. Holmes, Michaela Prchal-Murphy, Berislav Lisnić, Veronika Sexl, Yenan T. Bryceson, Felix M. Wensveen, Bojan Polić
Nat Immunol. Author manuscript; available in PMC 2019 Mar 17.
Published in final edited form as: Nat Immunol. 2018 Oct; 19(10): 1083–1092. Published online 2018 Sep 17. doi: 10.1038/s41590-018-0209-9
PMCID:
PMC6166863
AbstractArticlePDF–1.6M
12.
Downregulation of CD3ζ in Natural Killer Cells from Systemic Lupus Erythematosus Patients Confers a Pro-Inflammatory Phenotype
Abel Suárez-Fueyo, Sean J. Bradley, Takayuki Katsuyama, Sarah Solomon, Eri Katsuyama, Vasileios C. Kyttaris, Vaishali R. Moulton, George C. Tsokos
J Immunol. Author manuscript; available in PMC 2019 May 1.
Published in final edited form as: J Immunol. 2018 May 1; 200(9): 3077–3086. Published online 2018 Mar 30. doi: 10.4049/jimmunol.1700588
PMCID:
PMC6048443
AbstractArticlePDF–935K
13.
CD3 ITAM diversity is required for optimal T cell receptor signaling and thymocyte development
Matthew L. Bettini, Po-Chein Chou, Clifford Guy, Thomas Lee, Kate M. Vignali, Dario A.A. Vignali
J Immunol. Author manuscript; available in PMC 2018 Sep 1.
Published in final edited form as: J Immunol. 2017 Sep 1; 199(5): 1555–1560. Published online 2017 Jul 21. doi: 10.4049/jimmunol.1700069
PMCID:
PMC5568475
AbstractArticlePDF–674K
14.
The effects of immune protein CD3ζ development and degeneration of retinal neurons after optic nerve injury
Tao He, Xavier Mortensen, Ping Wang, Ning Tian
PLoS One. 2017; 12(4): e0175522. Published online 2017 Apr 25. doi: 10.1371/journal.pone.0175522
Correction in:
PLoS One. 2018; 13(6): e0198770.
PMCID:
PMC5404868
AbstractArticlePDF–7.5M
15.
Comprehensive Survey of miRNA-mRNA Interactions Reveals That Ccr7 and Cd247 (CD3 zeta) are Posttranscriptionally Controlled in Pancreas Infiltrating T Lymphocytes of Non-Obese Diabetic (NOD) Mice
Thais A. Fornari, Paula B. Donate, Amanda F. Assis, Claudia Macedo, Elza T. Sakamoto-Hojo, Eduardo A. Donadi, Geraldo A. Passos
PLoS One. 2015; 10(11): e0142688. Published online 2015 Nov 25. doi: 10.1371/journal.pone.0142688
PMCID:
PMC4659659
AbstractArticlePDF–2.9M
16.
Ligand engaged TCR is triggered by Lck not associated with CD8 coreceptor
Javier Casas, Joanna Brzostek, Veronika I. Zarnitsyna, Jin-sung Hong, Qianru Wei, John A.H. Hoerter, Guo Fu, Jeanette Ampudia, Rose Zamoyska, Cheng Zhu, Nicholas R.J. Gascoigne
Nat Commun. Author manuscript; available in PMC 2015 May 27.
Published in final edited form as: Nat Commun. 2014; 5: 5624. Published online 2014 Nov 27. doi: 10.1038/ncomms6624
PMCID:
PMC4248239
AbstractArticlePDF–2.1M
17.
T Cell CD3ζ Deficiency Enables Multiorgan Tissue Inflammation
Guo-Min Deng, Jessica Beltran, Chen Chen, Cox Terhorst, George C. Tsokos
J Immunol. Author manuscript; available in PMC 2014 Jun 25.
Published in final edited form as: J Immunol. 2013 Oct 1; 191(7): 3563–3567. Published online 2013 Aug 26. doi: 10.4049/jimmunol.1300634
PMCID:
PMC4070291
AbstractArticlePDF–772K
18.
Membrane association of the CD3ε signaling domain is required for optimal T cell development and function
Matthew L. Bettini, Clifford Guy, Pradyot Dash, Kate M. Vignali, David E. Hamm, Jessica Dobbins, Etienne Gagnon, Paul G. Thomas, Kai W. Wucherpfennig, Dario A.A. Vignali
J Immunol. Author manuscript; available in PMC 2015 Jul 1.
Published in final edited form as: J Immunol. 2014 Jul 1; 193(1): 258–267. Published online 2014 Jun 4. doi: 10.4049/jimmunol.1400322
PMCID:
PMC4065803
AbstractArticlePDF–1.4M
19.
Quantitative proteomic analysis of signalosome dynamics in primary T cells identifies the CD6 surface receptor as a Lat-independent TCR signaling hub
Romain Roncagalli, Simon Hauri, Fréderic Fiore, Yinming Liang, Zhi Chen, Amandine Sansoni, Kartiek Kanduri, Rachel Joly, Aurélie Malzac, Harri Lähdesmäki, Riitta Lahesmaa, Sho Yamasaki, Takashi Saito, Marie Malissen, Ruedi Aebersold, Matthias Gstaiger, Bernard Malissen
Nat Immunol. Author manuscript; available in PMC 2014 Oct 1.
Published in final edited form as: Nat Immunol. 2014 Apr; 15(4): 384–392. Published online 2014 Mar 2. doi: 10.1038/ni.2843
PMCID:
PMC4037560
AbstractArticlePDF–3.1M
20.
The Vertebrate Genome Annotation browser 10 years on
Jennifer L. Harrow, Charles A. Steward, Adam Frankish, James G. Gilbert, Jose M. Gonzalez, Jane E. Loveland, Jonathan Mudge, Dan Sheppard, Mark Thomas, Stephen Trevanion, Laurens G. Wilming
Nucleic Acids Res. 2014 Jan 1; 42(Database issue): D771–D779. Published online 2013 Dec 6. doi: 10.1093/nar/gkt1241
PMCID:
PMC3964964
AbstractArticlePDF–11M

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