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Items: 1 to 20 of 412

1.
Single-cell RNA transcriptomics in mice reveals embryonic origin of fibrosis due to maternal obesity
Md Nazmul Hossain, Yao Gao, Xinrui Li, Liang Zhao, Xiangdong Liu, Jeanene Marie de Avila, Mei-Jun Zhu, Min Du
eBioMedicine. 2024 Nov; 109: 105421. Published online 2024 Oct 30. doi: 10.1016/j.ebiom.2024.105421
PMCID:
PMC11565040
ArticlePDF–4.9M
2.
Hydrogen sulfide inhibits skeletal muscle ageing by up‐regulating autophagy through promoting deubiquitination of adenosine 5’‐monophosphate (AMP)‐activated protein kinase α1 via ubiquitin specific peptidase 5
Jia‐He Yang, Jun Gao, Ya‐Qi E, Li‐Jie Jiao, Ren Wu, Qiu‐Yi Yan, Zi‐Yi Wei, Guo‐Liang Yan, Jin‐Long Liang, Hong‐Zhu Li
J Cachexia Sarcopenia Muscle. 2024 Oct; 15(5): 2118–2133. Published online 2024 Aug 27. doi: 10.1002/jcsm.13560
PMCID:
PMC11446701
ArticlePDF–12M
3.
AMPK targets PDZD8 to trigger carbon source shift from glucose to glutamine
Mengqi Li, Yu Wang, Xiaoyan Wei, Wei-Feng Cai, Jianfeng Wu, Mingxia Zhu, Yongliang Wang, Yan-Hui Liu, Jinye Xiong, Qi Qu, Yan Chen, Xiao Tian, Luming Yao, Renxiang Xie, Xiaomin Li, Siwei Chen, Xi Huang, Cixiong Zhang, Changchuan Xie, Yaying Wu, Zheni Xu, Baoding Zhang, Bin Jiang, Zhi-Chao Wang, Qinxi Li, Gang Li, Shu-Yong Lin, Li Yu, Hai-Long Piao, Xianming Deng, Jiahuai Han, Chen-Song Zhang, Sheng-Cai Lin
Cell Res. 2024 Oct; 34(10): 683–706. Published online 2024 Jun 19. doi: 10.1038/s41422-024-00985-6
PMCID:
PMC11442470
ArticlePDF–6.2M
4.
Skeletal muscle-specific inducible AMPKα1/α2 knockout mice develop muscle weakness, glycogen depletion, and fibrosis that persists during disuse atrophy
Jonathan J. Petrocelli, Jingtong Liu, Elena M. Yee, Patrick J. Ferrara, Paul-Emile Bourrant, Naomi M. M. P. de Hart, Sean M. Tatum, William J. Holland, Katsuhiko Funai, Micah J. Drummond
Am J Physiol Endocrinol Metab. 2024 Jan 1; 326(1): E50–E60. Published online 2023 Nov 29. doi: 10.1152/ajpendo.00261.2023
PMCID:
PMC11193510
Article
5.
Apaf1-deficient cortical neurons exhibit defects in axonal outgrowth
Daniela De Zio, Francesca Molinari, Salvatore Rizza, Lucia Gatta, Maria Teresa Ciotti, Anna Maria Salvatore, Søs Grønbæk Mathiassen, Andrzej W. Cwetsch, Giuseppe Filomeni, Giuseppe Rosano, Elisabetta Ferraro
Cell Mol Life Sci. 2015 Nov; 72(21): 4173–4191. Published online 2015 May 15. doi: 10.1007/s00018-015-1927-x
PMCID:
PMC11113842
ArticlePDF–1.8M
6.
A novel AMPK-dependent FoxO3A-SIRT3 intramitochondrial complex sensing glucose levels
Alessia Peserico, Fulvio Chiacchiera, Valentina Grossi, Antonio Matrone, Dominga Latorre, Marta Simonatto, Aurora Fusella, James G. Ryall, Lydia W. S. Finley, Marcia C. Haigis, Gaetano Villani, Pier Lorenzo Puri, Vittorio Sartorelli, Cristiano Simone
Cell Mol Life Sci. 2013 Jun; 70(11): 2015–2029. Published online 2013 Jan 3. doi: 10.1007/s00018-012-1244-6
PMCID:
PMC11113715
ArticlePDF–1.3M
7.
SLC7A11-ROS/αKG-AMPK axis regulates liver inflammation through mitophagy and impairs liver fibrosis and NASH progression
Tingting Lv, Xiude Fan, Chang He, Suwei Zhu, Xiaofeng Xiong, Wei Yan, Mei Liu, Hongwei Xu, Ruihua Shi, Qin He
Redox Biol. 2024 Jun; 72: 103159. Published online 2024 Apr 16. doi: 10.1016/j.redox.2024.103159
PMCID:
PMC11047786
ArticlePDF–22M
8.
Loss of AMPK activity induces organelle dysfunction and oxidative stress during oocyte aging
Lin-Lin Hu, Mei-Hua Liao, Ya-Xi Liu, Chun-Hua Xing, Lan-Lan Nong, Feng-Lian Yang, Shao-Chen Sun
Biol Direct. 2024; 19: 29. Published online 2024 Apr 23. doi: 10.1186/s13062-024-00471-4
PMCID:
PMC11036640
ArticlePDF–11M
9.
The AMPK-related kinase NUAK1 controls cortical axons branching by locally modulating mitochondrial metabolic functions
Marine Lanfranchi, Sozerko Yandiev, Géraldine Meyer-Dilhet, Salma Ellouze, Martijn Kerkhofs, Raphael Dos Reis, Audrey Garcia, Camille Blondet, Alizée Amar, Anita Kneppers, Hélène Polvèche, Damien Plassard, Marc Foretz, Benoit Viollet, Kei Sakamoto, Rémi Mounier, Cyril F. Bourgeois, Olivier Raineteau, Evelyne Goillot, Julien Courchet
Nat Commun. 2024; 15: 2487. Published online 2024 Mar 21. doi: 10.1038/s41467-024-46146-6
PMCID:
PMC10958033
ArticlePDF–5.0M
10.
Activity-dependent compartmentalization of dendritic mitochondria morphology through local regulation of fusion-fission balance in neurons in vivo
Daniel M. Virga, Stevie Hamilton, Bertha Osei, Abigail Morgan, Parker Kneis, Emiliano Zamponi, Natalie J. Park, Victoria L. Hewitt, David Zhang, Kevin C. Gonzalez, Fiona M. Russell, D. Grahame Hardie, Julien Prudent, Erik Bloss, Attila Losonczy, Franck Polleux, Tommy L. Lewis, Jr
Nat Commun. 2024; 15: 2142. Published online 2024 Mar 8. doi: 10.1038/s41467-024-46463-w
PMCID:
PMC10923867
ArticlePDF–7.3M
11.
Endothelial H2S-AMPK dysfunction upregulates the angiocrine factor PAI-1 and contributes to lung fibrosis
Xiangqi Chen, Han Wang, Chuan Wu, Xiaoyan Li, Xiaojuan Huang, Yafeng Ren, Qiang Pu, Zhongwei Cao, Xiaoqiang Tang, Bi-Sen Ding
Redox Biol. 2024 Apr; 70: 103038. Published online 2024 Jan 11. doi: 10.1016/j.redox.2024.103038
PMCID:
PMC10811458
ArticlePDF–14M
12.
AMPKα1 negatively regulates osteoclastogenesis and mitigates pathological bone loss
Mariana S.P. Ribeiro, Lucas G.R. Venturini, Cesar A. Speck-Hernandez, Paulo V.G. Alabarse, Thais Xavier, Thaise M. Taira, Letícia F. Duffles, Fernando Q. Cunha, Sandra Y. Fukada
J Biol Chem. 2023 Dec; 299(12): 105379. Published online 2023 Oct 21. doi: 10.1016/j.jbc.2023.105379
PMCID:
PMC10692901
ArticlePDF–2.5M
13.
Metabolic orchestration of cell death by AMPK-mediated phosphorylation of RIPK1
Tao Zhang, Daichao Xu, Elijah Trefts, Mingming Lv, Hiroyuki Inuzuka, Guobin Song, Min Liu, Jianlin Lu, Jianping Liu, Chen Chu, Min Wang, Huibing Wang, Huyan Meng, Hui Liu, Yuan Zhuang, Xingxing Xie, Fabin Dang, Dongxian Guan, Yuqin Men, Shuwen Jiang, Cong Jiang, Xiaoming Dai, Jing Liu, Zhen Wang, Peiqiang Yan, Jingchao Wang, Zhenbo Tu, Mrigya Babuta, Emily Erickson, Alissandra L. Hillis, Christian C. Dibble, John M. Asara, Gyongy Szabo, Piotr Sicinski, Ji Miao, Yu-Ru Lee, Lifeng Pan, Reuben J. Shaw, Junying Yuan, Wenyi Wei
Science. Author manuscript; available in PMC 2023 Oct 31.
Published in final edited form as: Science. 2023 Jun 30; 380(6652): 1372–1380. Published online 2023 Jun 29. doi: 10.1126/science.abn1725
PMCID:
PMC10617018
ArticlePDF–2.3M
14.
Constitutively activated AMPKα1 protects against skeletal aging in mice by promoting bone‐derived IGF‐1 secretion
Yiqi Yang, Kai Yuan, Yihao Liu, Qishan Wang, Yixuan Lin, Shengbing Yang, Kai Huang, Tianyou Kan, Yuxin Zhang, Mingming Xu, Zhifeng Yu, Qiming Fan, Yugang Wang, Hanjun Li, Tingting Tang
Cell Prolif. 2023 Oct; 56(10): e13476. Published online 2023 Apr 11. doi: 10.1111/cpr.13476
PMCID:
PMC10542616
ArticlePDF–15M
15.
NLRP14 Safeguards Calcium Homeostasis via Regulating the K27 Ubiquitination of Nclx in Oocyte‐to‐Embryo Transition
Tie‐Gang Meng, Jia‐Ni Guo, Liu Zhu, Yike Yin, Feng Wang, Zhi‐Ming Han, Lei Lei, Xue‐Shan Ma, Yue Xue, Wei Yue, Xiao‐Qing Nie, Zheng‐Hui Zhao, Hong‐Yong Zhang, Si‐Min Sun, Ying‐Chun Ouyang, Yi Hou, Heide Schatten, Zhenyu Ju, Xiang‐Hong Ou, Zhen‐Bo Wang, Catherine C. L. Wong, Zhonghan Li, Qing‐Yuan Sun
Adv Sci (Weinh) 2023 Sep; 10(27): 2301940. Published online 2023 Jul 26. doi: 10.1002/advs.202301940
PMCID:
PMC10520637
ArticlePDF–6.6M
16.
KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility
Juan Gu, Pingyang Ke, Haokun Guo, Jing Liu, Yan Liu, Xin Tian, Zhuo Huang, Xin Xu, Demei Xu, Yuanlin Ma, Xuefeng Wang, Fei Xiao
Cell Death Differ. 2023 Jul; 30(7): 1726–1741. Published online 2023 May 4. doi: 10.1038/s41418-023-01174-5
PMCID:
PMC10307852
ArticlePDF–8.8M
17.
Downregulation of hepatic ceruloplasmin ameliorates NAFLD via SCO1-AMPK-LKB1 complex
Liping Xie, Yanmei Yuan, Simiao Xu, Sijia Lu, Jinyang Gu, Yanping Wang, Yibing Wang, Xianjing Zhang, Suzhen Chen, Jian Li, Junxi Lu, Honglin Sun, Ruixiang Hu, Hailong Piao, Wen Wang, Cunchuan Wang, Jing Wang, Na Li, Morris F. White, Liu Han, Weiping Jia, Ji Miao, Junli Liu
Cell Rep. Author manuscript; available in PMC 2023 May 2.
Published in final edited form as: Cell Rep. 2022 Oct 18; 41(3): 111498. doi: 10.1016/j.celrep.2022.111498
PMCID:
PMC10153649
ArticlePDF–1.6M
18.
Alpha-SNAP (M105I) mutation promotes neuronal differentiation of neural stem/progenitor cells through overactivation of AMPK
Felipe A. Bustamante-Barrientos, Maxs Méndez-Ruette, Luis Molina, Tania Koning, Pamela Ehrenfeld, Carlos B. González, Ursula Wyneken, Roberto Henzi, Luis Federico Bátiz
Front Cell Dev Biol. 2023; 11: 1061777. Published online 2023 Apr 11. doi: 10.3389/fcell.2023.1061777
PMCID:
PMC10127105
ArticlePDF–4.2M
19.
Monocytes re-enter the bone marrow during fasting and alter the host response to infection
Henrike Janssen, Florian Kahles, Dan Liu, Jeffrey Downey, Laura Koekkoek, Vladimir Roudko, Darwin D’Souza, Cameron S. McAlpine, Lennard Halle, Wolfram C. Poller, Christopher T. Chan, Shun He, John E. Mindur, Mate Kiss, Sumnima Singh, Atsushi Anzai, Yoshiko Iwamoto, Rainer H. Kohler, Kashish Chetal, Ruslan I. Sadreyev, Ralph Weissleder, Seunghee Kim-Schulze, Miriam Merad, Matthias Nahrendorf, Filip K. Swirski
Immunity. Author manuscript; available in PMC 2024 Apr 11.
Published in final edited form as: Immunity. 2023 Apr 11; 56(4): 783–796.e7. Published online 2023 Feb 23. doi: 10.1016/j.immuni.2023.01.024
PMCID:
PMC10101885
ArticlePDF–2.5M
20.
Ssu72 phosphatase is essential for thermogenic adaptation by regulating cytosolic translation
Eun-Ji Park, Hyun-Soo Kim, Do-Hyoung Lee, Su-Min Kim, Joon-Sup Yoon, Ji-Min Lee, Se Jin Im, Ho Lee, Min-Woo Lee, Chang-Woo Lee
Nat Commun. 2023; 14: 1097. Published online 2023 Feb 25. doi: 10.1038/s41467-023-36836-y
PMCID:
PMC9968297
ArticlePDF–4.4M

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